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The map label for this gene is queC

Identifier: 83593292

GI number: 83593292

Start: 2265645

End: 2266370

Strand: Direct

Name: queC

Synonym: Rru_A1957

Alternate gene names: 83593292

Gene position: 2265645-2266370 (Clockwise)

Preceding gene: 83593291

Following gene: 83593293

Centisome position: 52.05

GC content: 66.67

Gene sequence:

>726_bases
ATGCCCCACTCCCCAACGCAGCGCCGCGCCATCGTCTTGGTCAGCGGTGGCCTTGATTCCACCACCACCCTGGCCATCGC
CCAGGCCGAGGGCTTCACGGTCAACGCGCTTAGCTTCAGCTACGGCCAGCGCCATGCCGTGGAACTCGAGGCCGCCCGCC
GGGTCACCCAGGCCTTCGCGGTGGAGCGCCATGTCATCGCCACCATCGATCTCCGCCAGTTCGGCGGCTCGGCCCTGACC
GACAGCATCGGCGTTCCCAAGCAGCGGTCGCTGGAAACCATGGGCGCGGGCATCCCCGTCACCTATGTGCCCGCCCGCAA
CACCGTGTTCTTGTCCTTCGCCCTCGCCTGGGCCGAGGTGCTGGAGGCCAACGACGTGTTCATCGGCGTCAATGCCCTCG
ATTACAGCGGCTATCCCGATTGCCGGCCCGAATATATCAGCGCCTTCCAGACCATGGCCAATCTGGCGACCAAACGCGGC
GTCGAGGGAACGGGGGTTCTGACGATCCACACGCCGTTGATCGCCCTGACCAAAGGCCAGATCATCCGGCGCGGCCTTGA
TCTGGGGGTCGATTACGCGCTCACCCACAGCTGTTACGACCCCTCGGCCGAGGGTGAGGCCTGCGGCACCTGTGATTCCT
GCCTGCTGCGCTTGAAGGGCTTCGCCGAGAACGGCCTGGAGGATCCGGTGCGCTATGTCGGGGCGCGGTCACGGGCGGCG
GGGTGA

Upstream 100 bases:

>100_bases
GACAGCCTGACCCAATTGCTCGCCCGGCTTTATCCGCCCTCCCCCCTCGCCTCCCACGCTCCGTAATTCCCTCCGTTCTC
TGTCGCCAAGGAGTCCCCCC

Downstream 100 bases:

>100_bases
GCGCGATGATCGAGGGATTGCGCAGCGGCCTCAGCTTCGACGACGTGCTGCTGGTTCCCGGGCGGACCCGGGCGCGCAGC
CGCGCCGATATCACCCTTGC

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFAVERHVIATIDLRQFGGSALT
DSIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEVLEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRG
VEGTGVLTIHTPLIALTKGQIIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAA
G

Sequences:

>Translated_241_residues
MPHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFAVERHVIATIDLRQFGGSALT
DSIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEVLEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRG
VEGTGVLTIHTPLIALTKGQIIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAA
G
>Mature_240_residues
PHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFAVERHVIATIDLRQFGGSALTD
SIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEVLEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRGV
EGTGVLTIHTPLIALTKGQIIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAAG

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=229, Percent_Identity=34.9344978165939, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_RHORT (Q2RSY8)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427044.1
- ProteinModelPortal:   Q2RSY8
- SMR:   Q2RSY8
- STRING:   Q2RSY8
- GeneID:   3835381
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1957
- NMPDR:   fig|1085.1.peg.2531
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2RSY8
- ProtClustDB:   CLSK2773235
- BioCyc:   RRUB269796:RRU_A1957-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25738; Mature: 25607

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFA
CCCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCEEEHHHHHHHHHHHHH
VERHVIATIDLRQFGGSALTDSIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEV
HHHHEEEEEEHHHCCCCHHHHCCCCCCHHHHHHHCCCCCEEEECCCCEEEHHHHHHHHHH
LEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRGVEGTGVLTIHTPLIALTKGQ
HCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEHHHH
IIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAA
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
G
C
>Mature Secondary Structure 
PHSPTQRRAIVLVSGGLDSTTTLAIAQAEGFTVNALSFSYGQRHAVELEAARRVTQAFA
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCEEEHHHHHHHHHHHHH
VERHVIATIDLRQFGGSALTDSIGVPKQRSLETMGAGIPVTYVPARNTVFLSFALAWAEV
HHHHEEEEEEHHHCCCCHHHHCCCCCCHHHHHHHCCCCCEEEECCCCEEEHHHHHHHHHH
LEANDVFIGVNALDYSGYPDCRPEYISAFQTMANLATKRGVEGTGVLTIHTPLIALTKGQ
HCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEHHHH
IIRRGLDLGVDYALTHSCYDPSAEGEACGTCDSCLLRLKGFAENGLEDPVRYVGARSRAA
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA