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The map label for this gene is cat1 [H]

Identifier: 83593262

GI number: 83593262

Start: 2231609

End: 2233114

Strand: Reverse

Name: cat1 [H]

Synonym: Rru_A1927

Alternate gene names: 83593262

Gene position: 2233114-2231609 (Counterclockwise)

Preceding gene: 83593264

Following gene: 83593260

Centisome position: 51.3

GC content: 62.42

Gene sequence:

>1506_bases
ATGTATCGGGACCGTATCCGTCACCCCTCCTTGTTTGGCAAGGTGGTCAGCGCCGAAGAAGCCGCTAGCCTGATCAAAGA
TGGGATGACCGTTGGCATGAGCGGTTTCACCCGTTCGGGTGAGGCCAAGGCCGTCCCCTTTGCTTTGGCCGAACGGGCCA
AGACCGATCCTCTCAAGATTACCCTGTTGACCGGCGCCTCGCTCGGCAACGATCTGGACAAGACCCTGGTCGAGGCCGGT
GTTCTGGCCCGCCGCCTGCCGTTTCAGGCCGATCCGGCCCTGCGCAAGGCCATCAACCGGGGCGAGGTGATGTTCATCGA
TCAGCATCTCTCGGAAACCGTCGAGATGCTGCGTACCCGCCAGCTTGGCCCCATCGATGTCGCGGTGGTGGAAGCGGTGG
CGATCACCGAGGACGGCGGCATCATCCCCACGACCTCGGTCGGCAATTCGGCGACCTTCGCCATCCTCGCCGAAAAGGTC
ATCATCGAGATCAATCTGTCCCAGCCCGTCGAGCTTGAAGGGCTGCACGACATCTATATTCCGACGCGCCGCCCCTTCCG
CGAGCCGATTCCCATCGTGGCTTGCGAAAGCCGGGTCGGCCTGCCGTTCATCCCCATCGATCCGAGCAAGATCGCCGCGA
TCGTCGTCACCGAAAAGAAAGACAGCGCCGCCACCGTGGCGCCGCCCGATGCCGATACCCGCGCCATCGCCGGCCATCTG
ATCGAGTTCCTGCGCCACGAGGTCAGCCTGGGGCGCCTCAGCAATACCTTGCAGCCGCTGCAGGCGGGCATCGGGTCGAT
CGCCAACGCCGTGCTGCACGGCCTGATCGAGTCGCCCTTCCACAGCCTGAAGATGTATTCGGAAGTGCTGCAAGACAGCA
CCTTCGATCTGTTCGATGCCGGCAAGCTGCTGTTCGCCTCGGGCTCGTCGATCACGCTGTCGGAGGAAAAATACCGGGCG
GTCCTACCCAATCTCCCCAGCTACAAGAACCGCATCTTGTTGCGGCCCCAGGAGATCAGCAACCACCCCGAGATCATCCG
CCGCCTTGGCCTGATCGGCATTAATACCGCTCTGGAATTCGACCTTTACGGCAATGTCAATTCCACCCATGTCGGCGGCA
CGATGATGATGAACGGCATCGGCGGATCGGGAGACTTCGCGCGCAACTGCTATCTGTCGGTGTTCGTCACCAAGTCGATC
GCCAAGAACGGGGCGATTTCCAGCGTGGTGCCGATGGTCAGCCATGTCGATCATACCGAGCATGACGTGGATATCCTGAT
CACCGAAATCGGTCTGGCCGATCTGCGCGGTCTGGCGCCGCGCGAGCGGGCCAAGGTGGTGATCGATAACTGCGTCCACC
CGGCCTATCGCGATCAACTGGCCGATTACTATCGCCGGGCCCTGACCCGGGGCGGCCATACCCCCCATCTGATCGAAGAG
GCCTTCTCGTGGCATGTGCGGGCGGCCAAGACCGGTTCGATGCGCGAAGCCGTGGCCGCCGACTGA

Upstream 100 bases:

>100_bases
TTCTCATCACAAGGCTGGTTGCGATTGCAGCCAAGGGGGCGCATCGTTACCGTTCCCGTCAAGCTCCCCGCAGTGTGGAT
GCAACAACCAGGGAAATGCC

Downstream 100 bases:

>100_bases
CAAACGCCTTGTCGGCGGGGCCTTCCGGCATGGGGGGCCCCGCCGGAATTATCAGGGGGCGGGATGGCGGGCGCGCAGGC
GCTTGACCGAGTCCGGCAAA

Product: acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MYRDRIRHPSLFGKVVSAEEAASLIKDGMTVGMSGFTRSGEAKAVPFALAERAKTDPLKITLLTGASLGNDLDKTLVEAG
VLARRLPFQADPALRKAINRGEVMFIDQHLSETVEMLRTRQLGPIDVAVVEAVAITEDGGIIPTTSVGNSATFAILAEKV
IIEINLSQPVELEGLHDIYIPTRRPFREPIPIVACESRVGLPFIPIDPSKIAAIVVTEKKDSAATVAPPDADTRAIAGHL
IEFLRHEVSLGRLSNTLQPLQAGIGSIANAVLHGLIESPFHSLKMYSEVLQDSTFDLFDAGKLLFASGSSITLSEEKYRA
VLPNLPSYKNRILLRPQEISNHPEIIRRLGLIGINTALEFDLYGNVNSTHVGGTMMMNGIGGSGDFARNCYLSVFVTKSI
AKNGAISSVVPMVSHVDHTEHDVDILITEIGLADLRGLAPRERAKVVIDNCVHPAYRDQLADYYRRALTRGGHTPHLIEE
AFSWHVRAAKTGSMREAVAAD

Sequences:

>Translated_501_residues
MYRDRIRHPSLFGKVVSAEEAASLIKDGMTVGMSGFTRSGEAKAVPFALAERAKTDPLKITLLTGASLGNDLDKTLVEAG
VLARRLPFQADPALRKAINRGEVMFIDQHLSETVEMLRTRQLGPIDVAVVEAVAITEDGGIIPTTSVGNSATFAILAEKV
IIEINLSQPVELEGLHDIYIPTRRPFREPIPIVACESRVGLPFIPIDPSKIAAIVVTEKKDSAATVAPPDADTRAIAGHL
IEFLRHEVSLGRLSNTLQPLQAGIGSIANAVLHGLIESPFHSLKMYSEVLQDSTFDLFDAGKLLFASGSSITLSEEKYRA
VLPNLPSYKNRILLRPQEISNHPEIIRRLGLIGINTALEFDLYGNVNSTHVGGTMMMNGIGGSGDFARNCYLSVFVTKSI
AKNGAISSVVPMVSHVDHTEHDVDILITEIGLADLRGLAPRERAKVVIDNCVHPAYRDQLADYYRRALTRGGHTPHLIEE
AFSWHVRAAKTGSMREAVAAD
>Mature_501_residues
MYRDRIRHPSLFGKVVSAEEAASLIKDGMTVGMSGFTRSGEAKAVPFALAERAKTDPLKITLLTGASLGNDLDKTLVEAG
VLARRLPFQADPALRKAINRGEVMFIDQHLSETVEMLRTRQLGPIDVAVVEAVAITEDGGIIPTTSVGNSATFAILAEKV
IIEINLSQPVELEGLHDIYIPTRRPFREPIPIVACESRVGLPFIPIDPSKIAAIVVTEKKDSAATVAPPDADTRAIAGHL
IEFLRHEVSLGRLSNTLQPLQAGIGSIANAVLHGLIESPFHSLKMYSEVLQDSTFDLFDAGKLLFASGSSITLSEEKYRA
VLPNLPSYKNRILLRPQEISNHPEIIRRLGLIGINTALEFDLYGNVNSTHVGGTMMMNGIGGSGDFARNCYLSVFVTKSI
AKNGAISSVVPMVSHVDHTEHDVDILITEIGLADLRGLAPRERAKVVIDNCVHPAYRDQLADYYRRALTRGGHTPHLIEE
AFSWHVRAAKTGSMREAVAAD

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=47.0103092783505, Blast_Score=427, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6319456, Length=515, Percent_Identity=43.3009708737864, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54394; Mature: 54394

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDRIRHPSLFGKVVSAEEAASLIKDGMTVGMSGFTRSGEAKAVPFALAERAKTDPLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLLTGASLGNDLDKTLVEAGVLARRLPFQADPALRKAINRGEVMFIDQHLSETVEMLRTR
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHC
QLGPIDVAVVEAVAITEDGGIIPTTSVGNSATFAILAEKVIIEINLSQPVELEGLHDIYI
CCCCCHHHHHEEEEEECCCCEECCCCCCCCEEHEEEEEEEEEEEECCCCCCCCCCCEEEC
PTRRPFREPIPIVACESRVGLPFIPIDPSKIAAIVVTEKKDSAATVAPPDADTRAIAGHL
CCCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEEEECCCCCCEECCCCCCHHHHHHHH
IEFLRHEVSLGRLSNTLQPLQAGIGSIANAVLHGLIESPFHSLKMYSEVLQDSTFDLFDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCC
GKLLFASGSSITLSEEKYRAVLPNLPSYKNRILLRPQEISNHPEIIRRLGLIGINTALEF
CCEEEECCCEEEECHHHHHHHCCCCCCCCCEEEECHHHHCCCHHHHHHHCCEEECCEEEE
DLYGNVNSTHVGGTMMMNGIGGSGDFARNCYLSVFVTKSIAKNGAISSVVPMVSHVDHTE
EEECCCCCCCCCCEEEEECCCCCCCHHHHEEEEEEEEHHHHCCCCHHHHHHHHHHCCCCC
HDVDILITEIGLADLRGLAPRERAKVVIDNCVHPAYRDQLADYYRRALTRGGHTPHLIEE
CCCEEEEEHHCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AFSWHVRAAKTGSMREAVAAD
HHHHEEEECCCCCHHHHHCCC
>Mature Secondary Structure
MYRDRIRHPSLFGKVVSAEEAASLIKDGMTVGMSGFTRSGEAKAVPFALAERAKTDPLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLLTGASLGNDLDKTLVEAGVLARRLPFQADPALRKAINRGEVMFIDQHLSETVEMLRTR
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHC
QLGPIDVAVVEAVAITEDGGIIPTTSVGNSATFAILAEKVIIEINLSQPVELEGLHDIYI
CCCCCHHHHHEEEEEECCCCEECCCCCCCCEEHEEEEEEEEEEEECCCCCCCCCCCEEEC
PTRRPFREPIPIVACESRVGLPFIPIDPSKIAAIVVTEKKDSAATVAPPDADTRAIAGHL
CCCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEEEECCCCCCEECCCCCCHHHHHHHH
IEFLRHEVSLGRLSNTLQPLQAGIGSIANAVLHGLIESPFHSLKMYSEVLQDSTFDLFDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCC
GKLLFASGSSITLSEEKYRAVLPNLPSYKNRILLRPQEISNHPEIIRRLGLIGINTALEF
CCEEEECCCEEEECHHHHHHHCCCCCCCCCEEEECHHHHCCCHHHHHHHCCEEECCEEEE
DLYGNVNSTHVGGTMMMNGIGGSGDFARNCYLSVFVTKSIAKNGAISSVVPMVSHVDHTE
EEECCCCCCCCCCEEEEECCCCCCCHHHHEEEEEEEEHHHHCCCCHHHHHHHHHHCCCCC
HDVDILITEIGLADLRGLAPRERAKVVIDNCVHPAYRDQLADYYRRALTRGGHTPHLIEE
CCCEEEEEHHCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AFSWHVRAAKTGSMREAVAAD
HHHHEEEECCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]