Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 83593200

GI number: 83593200

Start: 2161583

End: 2162464

Strand: Reverse

Name: dapA [H]

Synonym: Rru_A1865

Alternate gene names: 83593200

Gene position: 2162464-2161583 (Counterclockwise)

Preceding gene: 83593202

Following gene: 83593199

Centisome position: 49.68

GC content: 66.33

Gene sequence:

>882_bases
ATGTTGCAGGGCTCCATCACCGCCCTCGTCACCCCGTTCCGCGACGGAGCGGTCGACCAGCGCGCCTTCCAGGATTTCGT
GGCCTGGCAGATCGCCGAAGGCACCCAGGGCCTGGTGCCCGTGGGCACCACCGGAGAATCGCCGACGCTGAGCCATGACG
AGCACAAACGGGTGGTGGAACTTTGCGTCGAGGTCGCCAAAGGCAAGGTGCCGGTGATCGCCGGGGCTGGATCGAATTCC
ACGGCCGAGGCGGTTGATTTCACCCGTCACGCGGTGAAGACCGGGGCCGACGCGGTTCTGGTGGTGACCCCCTATTATAA
CAAGCCCACCCAGGAAGGGCTCTATCAGCACTTCAAGGCCGTGGCCGGTGCCGCCGGTGATCTGCCGGTGATCATCTATA
ACATCCCCGGTCGCTCGATCGTCGACATGAGCGTCGAGACCATGGCCCGTCTGGCCCACGACCTGCCCAATATCAAAGGG
GTGAAGGACGCGACCGCCGATCTGGCCCGGCCGCTCAAGACCCGGGTGGTTCTGGGGCCCGAGTTCATCCAGCTGTCGGG
CGAGGACGCCACGGCGACCGCCTTCCTCGCCCAGGGCGGGGTGGGCTGTATCTCGGTCACCTCGAACGTCGCCCCCCGCC
TGTGCGCCGAGATGCAGCGCAGCTGGCGCGAGGGCGATCTGGCGACCTGCTTTGCCATCCGCGACAAGCTGATGCCGCTG
CATGACGCCATGTTCTGCGAGACCAGCCCGGGCCCGGTGAAATACGCCGTCAGCCTGCTTGGCAAGGGCTCGGCCGAAAC
CCGCCTGCCGATGGTGCCGATTTCCGAGGCCTCGCGTAAAAAGGTCGAAGAGGCCCTGCGGGCGACCGGTCTGCTCGCCT
GA

Upstream 100 bases:

>100_bases
CCTGCCTATAGGTTCTTGCCGGGGAACACCACTGTGCTAAAACACAAGCTTTCGCACTCGCGGCGTCCGCCTAAAATGAA
GTGATATTATGGAGAACACC

Downstream 100 bases:

>100_bases
CAGAGCGCCCCCCTTTCTTTTATTCGGAGATCATTGGACCGGCATGGCACGCGCTGGCAATAGCCTGATATCCCACGGAC
GGGTGGCGGAAAACCGCCGG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLQGSITALVTPFRDGAVDQRAFQDFVAWQIAEGTQGLVPVGTTGESPTLSHDEHKRVVELCVEVAKGKVPVIAGAGSNS
TAEAVDFTRHAVKTGADAVLVVTPYYNKPTQEGLYQHFKAVAGAAGDLPVIIYNIPGRSIVDMSVETMARLAHDLPNIKG
VKDATADLARPLKTRVVLGPEFIQLSGEDATATAFLAQGGVGCISVTSNVAPRLCAEMQRSWREGDLATCFAIRDKLMPL
HDAMFCETSPGPVKYAVSLLGKGSAETRLPMVPISEASRKKVEEALRATGLLA

Sequences:

>Translated_293_residues
MLQGSITALVTPFRDGAVDQRAFQDFVAWQIAEGTQGLVPVGTTGESPTLSHDEHKRVVELCVEVAKGKVPVIAGAGSNS
TAEAVDFTRHAVKTGADAVLVVTPYYNKPTQEGLYQHFKAVAGAAGDLPVIIYNIPGRSIVDMSVETMARLAHDLPNIKG
VKDATADLARPLKTRVVLGPEFIQLSGEDATATAFLAQGGVGCISVTSNVAPRLCAEMQRSWREGDLATCFAIRDKLMPL
HDAMFCETSPGPVKYAVSLLGKGSAETRLPMVPISEASRKKVEEALRATGLLA
>Mature_293_residues
MLQGSITALVTPFRDGAVDQRAFQDFVAWQIAEGTQGLVPVGTTGESPTLSHDEHKRVVELCVEVAKGKVPVIAGAGSNS
TAEAVDFTRHAVKTGADAVLVVTPYYNKPTQEGLYQHFKAVAGAAGDLPVIIYNIPGRSIVDMSVETMARLAHDLPNIKG
VKDATADLARPLKTRVVLGPEFIQLSGEDATATAFLAQGGVGCISVTSNVAPRLCAEMQRSWREGDLATCFAIRDKLMPL
HDAMFCETSPGPVKYAVSLLGKGSAETRLPMVPISEASRKKVEEALRATGLLA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=302, Percent_Identity=26.8211920529801, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI31543060, Length=255, Percent_Identity=27.843137254902, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1788823, Length=294, Percent_Identity=46.9387755102041, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI87082415, Length=286, Percent_Identity=34.6153846153846, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786463, Length=276, Percent_Identity=29.7101449275362, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789620, Length=229, Percent_Identity=32.7510917030568, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31083; Mature: 31083

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQGSITALVTPFRDGAVDQRAFQDFVAWQIAEGTQGLVPVGTTGESPTLSHDEHKRVVE
CCCCCEEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCCHHHHHHHH
LCVEVAKGKVPVIAGAGSNSTAEAVDFTRHAVKTGADAVLVVTPYYNKPTQEGLYQHFKA
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
VAGAAGDLPVIIYNIPGRSIVDMSVETMARLAHDLPNIKGVKDATADLARPLKTRVVLGP
HHCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECC
EFIQLSGEDATATAFLAQGGVGCISVTSNVAPRLCAEMQRSWREGDLATCFAIRDKLMPL
CEEEECCCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
HDAMFCETSPGPVKYAVSLLGKGSAETRLPMVPISEASRKKVEEALRATGLLA
HHHHEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQGSITALVTPFRDGAVDQRAFQDFVAWQIAEGTQGLVPVGTTGESPTLSHDEHKRVVE
CCCCCEEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCCHHHHHHHH
LCVEVAKGKVPVIAGAGSNSTAEAVDFTRHAVKTGADAVLVVTPYYNKPTQEGLYQHFKA
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
VAGAAGDLPVIIYNIPGRSIVDMSVETMARLAHDLPNIKGVKDATADLARPLKTRVVLGP
HHCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECC
EFIQLSGEDATATAFLAQGGVGCISVTSNVAPRLCAEMQRSWREGDLATCFAIRDKLMPL
CEEEECCCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
HDAMFCETSPGPVKYAVSLLGKGSAETRLPMVPISEASRKKVEEALRATGLLA
HHHHEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA