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The map label for this gene is kipI [H]

Identifier: 83592842

GI number: 83592842

Start: 1779986

End: 1780717

Strand: Reverse

Name: kipI [H]

Synonym: Rru_A1506

Alternate gene names: 83592842

Gene position: 1780717-1779986 (Counterclockwise)

Preceding gene: 83592843

Following gene: 83592841

Centisome position: 40.91

GC content: 71.04

Gene sequence:

>732_bases
GTGACCGACACGCTGACCCTGGTCAGCGCCGGCGATTGCGCCTTCGGCGTGGTCTTTGGCGAAACGATCACGCCGGCGGT
CAATGCCCGGGTCCAGGCCCTGCATCGGCGGCTTCGCGCCCAGGCCGCCGAGTTTCCCGGGCTGATCGAAAGCGTGCCGG
GCTTTACCACCTTGCTGATCCATTACGATCCGCTGCTGACCGGGCGGGCCGAGCTTGAGCCGCGCCTGCGCGCCCTGCTT
GCCGAGGCGTCGGTCGAACCGGCGCAAGGCCGGGCGTGGCGGCTGCCGGTCTGTTACCAGGGCTCCCCCGATCTTGACGC
CGTCGCCCGCGCCACGGGGTTGTCGGCGGCCGAGGTGACCGCCCGGCATGAACAGGGGCGCTATGTCGTTTATGTGCTGG
GCTTCCTGCCGGGCTTTGCCTATCTCGGCGATCTGGACCCGGCGCTCGCCCTGCCGCGCCGGGCCGAGCCCCGGCTGACG
GTGCCGGCGGGATCCCTGGCGATCGCCGAGCGCCTGACCGCCGTCTATCCCTGGGAAAGCCCCGGCGGCTGGCATCTGAT
CGGCCATTGCCCGGTGCCGCTGTTCAACGCGTCCCAGGCCAGCCCGGCCCTGCTGGCGCCGGGCGATCAGCTTCGTTTCT
TCGCCGTCAACCGGGCCGAGCATGAGGCCTGGGTCCGCCGCGTCGCCGAGCCGGGCTTCGATCCCGCTGATTTGATCGAC
GGCGCGCCATGA

Upstream 100 bases:

>100_bases
ATGGCCGCCAAATAGCACGGCAAACCGTCGGCCGGAATTGCCCCCCGGCCAGGGTCCGGGGTAGCCTGGGGCGTCACGGC
GATGGGAAAGGAATAAACCG

Downstream 100 bases:

>100_bases
ACACGCCCCATCTGCGGGTCATCACCCCGGGTCTGCTGACGACGCTCCAGGACCTCGGTCGCTGGGGCTTTCAAGATCGC
GGGGTACCGGTGGCCGGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTDTLTLVSAGDCAFGVVFGETITPAVNARVQALHRRLRAQAAEFPGLIESVPGFTTLLIHYDPLLTGRAELEPRLRALL
AEASVEPAQGRAWRLPVCYQGSPDLDAVARATGLSAAEVTARHEQGRYVVYVLGFLPGFAYLGDLDPALALPRRAEPRLT
VPAGSLAIAERLTAVYPWESPGGWHLIGHCPVPLFNASQASPALLAPGDQLRFFAVNRAEHEAWVRRVAEPGFDPADLID
GAP

Sequences:

>Translated_243_residues
MTDTLTLVSAGDCAFGVVFGETITPAVNARVQALHRRLRAQAAEFPGLIESVPGFTTLLIHYDPLLTGRAELEPRLRALL
AEASVEPAQGRAWRLPVCYQGSPDLDAVARATGLSAAEVTARHEQGRYVVYVLGFLPGFAYLGDLDPALALPRRAEPRLT
VPAGSLAIAERLTAVYPWESPGGWHLIGHCPVPLFNASQASPALLAPGDQLRFFAVNRAEHEAWVRRVAEPGFDPADLID
GAP
>Mature_242_residues
TDTLTLVSAGDCAFGVVFGETITPAVNARVQALHRRLRAQAAEFPGLIESVPGFTTLLIHYDPLLTGRAELEPRLRALLA
EASVEPAQGRAWRLPVCYQGSPDLDAVARATGLSAAEVTARHEQGRYVVYVLGFLPGFAYLGDLDPALALPRRAEPRLTV
PAGSLAIAERLTAVYPWESPGGWHLIGHCPVPLFNASQASPALLAPGDQLRFFAVNRAEHEAWVRRVAEPGFDPADLIDG
AP

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=206, Percent_Identity=40.2912621359223, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 26089; Mature: 25958

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTLTLVSAGDCAFGVVFGETITPAVNARVQALHRRLRAQAAEFPGLIESVPGFTTLLI
CCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEE
HYDPLLTGRAELEPRLRALLAEASVEPAQGRAWRLPVCYQGSPDLDAVARATGLSAAEVT
EECCCCCCCHHCCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCHHHHHHHHCCCHHHHH
ARHEQGRYVVYVLGFLPGFAYLGDLDPALALPRRAEPRLTVPAGSLAIAERLTAVYPWES
HHHCCCCEEEEEEHHHCHHHHHCCCCHHHCCCCCCCCCEECCCCHHHHHHHHHEECCCCC
PGGWHLIGHCPVPLFNASQASPALLAPGDQLRFFAVNRAEHEAWVRRVAEPGFDPADLID
CCCEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHCC
GAP
CCC
>Mature Secondary Structure 
TDTLTLVSAGDCAFGVVFGETITPAVNARVQALHRRLRAQAAEFPGLIESVPGFTTLLI
CCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEE
HYDPLLTGRAELEPRLRALLAEASVEPAQGRAWRLPVCYQGSPDLDAVARATGLSAAEVT
EECCCCCCCHHCCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCHHHHHHHHCCCHHHHH
ARHEQGRYVVYVLGFLPGFAYLGDLDPALALPRRAEPRLTVPAGSLAIAERLTAVYPWES
HHHCCCCEEEEEEHHHCHHHHHCCCCHHHCCCCCCCCCEECCCCHHHHHHHHHEECCCCC
PGGWHLIGHCPVPLFNASQASPALLAPGDQLRFFAVNRAEHEAWVRRVAEPGFDPADLID
CCCEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHCC
GAP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]