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The map label for this gene is wecB [H]

Identifier: 83592829

GI number: 83592829

Start: 1763172

End: 1764326

Strand: Reverse

Name: wecB [H]

Synonym: Rru_A1493

Alternate gene names: 83592829

Gene position: 1764326-1763172 (Counterclockwise)

Preceding gene: 83592834

Following gene: 83592828

Centisome position: 40.53

GC content: 68.74

Gene sequence:

>1155_bases
GTGTCGCTCTTATCAAAAAAAAAACAGCCTACCGGTGCCCCCCTTCTGGTCGTCATCGGAACACGACCCGAAGCCATCAA
ACTCGCCCCCGTGGTTCTGGCCCTGCGCCGGAACGCCCGGGTGCCGGTCAAGGTCTGCCTCAGCGGTCAGCACCGTGACC
TGCTGACCCAGGGGCTCTCGGCCTTCGATCTGACCATCGACCATAGCCTGGACCTGATGACCCCCGATCAGCGCCCAAGC
GATCTGGTGGCGCGGGTCATCACCGGCCTGACCCCGGTCATCGAAGCCACCGCTCCGGCTTGGCTGGTGGTTCAGGGCGA
CACGACAACGGCGCTGGGCGCCGCCCTGGCCGGCTTCCACGCCCGGCTCGACGTCGCCCATGTCGAAGCCGGCCTGCGCA
GCGGCGATCGCGCCGCCCCCTGGCCCGAGGAGATGAACCGCCGGCTGATCGGCCAGATCGCGGCGCTGCATTTCGCCCCG
ACCGAGCGCGCCCGGGCCAATCTTCTGGCCGAAGGCGTGGCCGAGGGCGCTATCGAGGTCACCGGCAACACGGTGATCGA
CGCCCTGCATCTGGCCCTGGCCCGCATCAAGGACACCCCCCGGGTCATCGAGGCCGCCGCGCCGATCCTGGCCACGGCGG
GCGAACGCGCCCTGGTCCTGGTCACCATCCACCGCCGCGAAAGCCTGGGCGAGGCCTTGCCGCGCTTGGCCGAGGCGCTT
CTTGGGCTGGCCAAGGCCGAGGAGCGGTTGATCGTTCTGCCCATTCATCCCAATCCGCGCCTCGCCCCGCTGATCGAGGC
GCTGAGCGGTCATCCCGGCATCTTGCTGACCCCGGCGCTTGATTATCTGCCCTTCGTCGCCCTGCTCCATCGCGCCGATC
TGATCCTGACCGATTCCGGGGGCATCCAGGAAGAGGCCTCGGCGCTTGGCAAACCGGTTCTGGTGCTGCGCGACACCACC
GAGCGCCCCGAACTGGTCGCCGGCGGCAACGGCTTGGTGGTCGGCACCCGGACCGCCCGGATTCTCGACCATGCCCTGCC
GCTGCTGACCGACCCGGCCGCCCGCGCCGCTTTGGCCCAAACCCATGACGGTTTCGGCGATGGCCATGCCGCCGAGCGCA
TCGCCCAAACCCTCGAAAATCGGATTGCCCCATGA

Upstream 100 bases:

>100_bases
TCCCGCATCGTTTCGTGGTCTTCCCCTAAAACTGTCCGCATCACGGTTTCTTACACGCCCGCCGCAGTATAAAACAGAAG
CCTGTGTTTGGAGGGTTCGC

Downstream 100 bases:

>100_bases
CGCTCAGCGCCAATGACCTGATTTTCCGCGCCCTGCTCGCCCTTGTCGTTCTAGCGCCCTTGCCTTTGGGGGCCAATCGG
CCGGCGGCCTGGAGCGCGCT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSLLSKKKQPTGAPLLVVIGTRPEAIKLAPVVLALRRNARVPVKVCLSGQHRDLLTQGLSAFDLTIDHSLDLMTPDQRPS
DLVARVITGLTPVIEATAPAWLVVQGDTTTALGAALAGFHARLDVAHVEAGLRSGDRAAPWPEEMNRRLIGQIAALHFAP
TERARANLLAEGVAEGAIEVTGNTVIDALHLALARIKDTPRVIEAAAPILATAGERALVLVTIHRRESLGEALPRLAEAL
LGLAKAEERLIVLPIHPNPRLAPLIEALSGHPGILLTPALDYLPFVALLHRADLILTDSGGIQEEASALGKPVLVLRDTT
ERPELVAGGNGLVVGTRTARILDHALPLLTDPAARAALAQTHDGFGDGHAAERIAQTLENRIAP

Sequences:

>Translated_384_residues
MSLLSKKKQPTGAPLLVVIGTRPEAIKLAPVVLALRRNARVPVKVCLSGQHRDLLTQGLSAFDLTIDHSLDLMTPDQRPS
DLVARVITGLTPVIEATAPAWLVVQGDTTTALGAALAGFHARLDVAHVEAGLRSGDRAAPWPEEMNRRLIGQIAALHFAP
TERARANLLAEGVAEGAIEVTGNTVIDALHLALARIKDTPRVIEAAAPILATAGERALVLVTIHRRESLGEALPRLAEAL
LGLAKAEERLIVLPIHPNPRLAPLIEALSGHPGILLTPALDYLPFVALLHRADLILTDSGGIQEEASALGKPVLVLRDTT
ERPELVAGGNGLVVGTRTARILDHALPLLTDPAARAALAQTHDGFGDGHAAERIAQTLENRIAP
>Mature_383_residues
SLLSKKKQPTGAPLLVVIGTRPEAIKLAPVVLALRRNARVPVKVCLSGQHRDLLTQGLSAFDLTIDHSLDLMTPDQRPSD
LVARVITGLTPVIEATAPAWLVVQGDTTTALGAALAGFHARLDVAHVEAGLRSGDRAAPWPEEMNRRLIGQIAALHFAPT
ERARANLLAEGVAEGAIEVTGNTVIDALHLALARIKDTPRVIEAAAPILATAGERALVLVTIHRRESLGEALPRLAEALL
GLAKAEERLIVLPIHPNPRLAPLIEALSGHPGILLTPALDYLPFVALLHRADLILTDSGGIQEEASALGKPVLVLRDTTE
RPELVAGGNGLVVGTRTARILDHALPLLTDPAARAALAQTHDGFGDGHAAERIAQTLENRIAP

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=45.2574525745258, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40586; Mature: 40454

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSKKKQPTGAPLLVVIGTRPEAIKLAPVVLALRRNARVPVKVCLSGQHRDLLTQGLS
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCC
AFDLTIDHSLDLMTPDQRPSDLVARVITGLTPVIEATAPAWLVVQGDTTTALGAALAGFH
CEEEEEECCEECCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
ARLDVAHVEAGLRSGDRAAPWPEEMNRRLIGQIAALHFAPTERARANLLAEGVAEGAIEV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
TGNTVIDALHLALARIKDTPRVIEAAAPILATAGERALVLVTIHRRESLGEALPRLAEAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHH
LGLAKAEERLIVLPIHPNPRLAPLIEALSGHPGILLTPALDYLPFVALLHRADLILTDSG
HHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCEEEECCC
GIQEEASALGKPVLVLRDTTERPELVAGGNGLVVGTRTARILDHALPLLTDPAARAALAQ
CCHHHHHHCCCCEEEEECCCCCCCEEECCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHH
THDGFGDGHAAERIAQTLENRIAP
CCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLLSKKKQPTGAPLLVVIGTRPEAIKLAPVVLALRRNARVPVKVCLSGQHRDLLTQGLS
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCC
AFDLTIDHSLDLMTPDQRPSDLVARVITGLTPVIEATAPAWLVVQGDTTTALGAALAGFH
CEEEEEECCEECCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
ARLDVAHVEAGLRSGDRAAPWPEEMNRRLIGQIAALHFAPTERARANLLAEGVAEGAIEV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEE
TGNTVIDALHLALARIKDTPRVIEAAAPILATAGERALVLVTIHRRESLGEALPRLAEAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHH
LGLAKAEERLIVLPIHPNPRLAPLIEALSGHPGILLTPALDYLPFVALLHRADLILTDSG
HHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCEEEECCC
GIQEEASALGKPVLVLRDTTERPELVAGGNGLVVGTRTARILDHALPLLTDPAARAALAQ
CCHHHHHHCCCCEEEEECCCCCCCEEECCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHH
THDGFGDGHAAERIAQTLENRIAP
CCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]