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The map label for this gene is hutI

Identifier: 83592639

GI number: 83592639

Start: 1537507

End: 1538751

Strand: Direct

Name: hutI

Synonym: Rru_A1303

Alternate gene names: 83592639

Gene position: 1537507-1538751 (Clockwise)

Preceding gene: 83592635

Following gene: 83592640

Centisome position: 35.32

GC content: 70.12

Gene sequence:

>1245_bases
ATGGCGCAAGCACCCTGGGACAGCCTGTGGCTCAACGGCTCGCTGGCCACCATGGCCGCAGGCGGGGCGGCCTATGGCGC
GATCGAGGATGGCGCCATCGCCGTGGCCGACGGGCGCCTGGTTTTCGTCGGCCGCCGCGCCGATCTGCCCCCGGGCGCCG
AGGATCGGGCCGCCAGCCTTCACGATTTGGGGGGGCGCTGGGTCACTCCGGGACTGATCGATTGCCATACCCACCTTGTT
TACGCCGGCAGCCGCGCCCGTGAGTTCGAGCTTCGGCTGCAAGGCGCCAGCTATGAGGAGATCGCCCGCGCCGGCGGCGG
CATCGTCTCCACCGTCGGCGCGACGCGGGCCGCCAGCCTTGACCAACTGATCGCCAGCGCCTTGCCCCGGCTTGACGCCC
TGCTGGCCGAAGGGGTGACGACGCTCGAGATCAAATCGGGCTATGGGCTGACGATTGAAAGCGAACGGCGCCTGTTGCAG
GCCGCCCGCGCGCTGGGTCGGCGGCGCCCCGTTGATGTGGTGACGACCTTTCTTGGCGCCCATGCCCTGCCGCCGGAATT
TTCCGGGGATGGCAATGGCTATATCGATCACCTCTGCGCGTCGATGCTGCCCGCCCTGGCGGCCGAGGGGCTGGTCGACG
CCGTCGATGTCTTTTGCGAGACCATCGCCTTTTCCCTTGCCCAGGCCACCCGGGTTTTTGAAGCGGCGCGGGGCTTGGGC
CTGCCGGTCAAGGTCCATGCCGAACAGCTTGGCCTGCTGGGCGGGGCGGCGCTGGCGGCGGGCTTTGGCGCGCTGTCGGC
CGATCATGTCGAATACCTCGACGAGGCCGGGGTGCGGGCCCTGGCGGCGGCGGGAACGGTGGCGGTGCTGCTGCCCGGCG
CCTTTCATATGCTGCGCGAAACCCAAAGGCCGCCGGTCGACGCCCTGCGCCGCTTCGGCGTGGCGATCGCCATCGCCACC
GATTGCAACCCCGGCACCTCGCCCGTCACCTCGCCGCTGCTCATGCTCAACATGGCCTGCGTGCTCTTCCGCCTGACCCC
CGAGGAGGCCCTGGCCGGGCTGACCCGCAATGGCGCCAAGGCGCTGGGCTTAAGCGATCGCGGCGTGCTGGCCCCCGGTT
TGCGCGCCGATTTCGCCCTGTGGGATATCGGCCATCCCGCTGAACTGGCCTATGCGCTGGGGCTCAACCCCTGTCATGCC
GTGGTGCGGGCCGGCGAACCACGGCCGCCGCGCGCCCCCTTTTGA

Upstream 100 bases:

>100_bases
CCGGCCCCTCTTATTATAGACAAGCTTATACAAGATTAGGCAACCTGCCGAAAGCCTGAAAAACCGAGCCTTCGCGGGCT
CTGATCGGAGCGGGGACGCG

Downstream 100 bases:

>100_bases
TCCTCACCCCAAGGAGCTGAGCCTTCGCCATGTCCGATCGTCTCGACAATCAGCGCGTGGTGCGCGCCCCCCGTGGCCCC
GAGATCACTTGCAAAAGCTG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MAQAPWDSLWLNGSLATMAAGGAAYGAIEDGAIAVADGRLVFVGRRADLPPGAEDRAASLHDLGGRWVTPGLIDCHTHLV
YAGSRAREFELRLQGASYEEIARAGGGIVSTVGATRAASLDQLIASALPRLDALLAEGVTTLEIKSGYGLTIESERRLLQ
AARALGRRRPVDVVTTFLGAHALPPEFSGDGNGYIDHLCASMLPALAAEGLVDAVDVFCETIAFSLAQATRVFEAARGLG
LPVKVHAEQLGLLGGAALAAGFGALSADHVEYLDEAGVRALAAAGTVAVLLPGAFHMLRETQRPPVDALRRFGVAIAIAT
DCNPGTSPVTSPLLMLNMACVLFRLTPEEALAGLTRNGAKALGLSDRGVLAPGLRADFALWDIGHPAELAYALGLNPCHA
VVRAGEPRPPRAPF

Sequences:

>Translated_414_residues
MAQAPWDSLWLNGSLATMAAGGAAYGAIEDGAIAVADGRLVFVGRRADLPPGAEDRAASLHDLGGRWVTPGLIDCHTHLV
YAGSRAREFELRLQGASYEEIARAGGGIVSTVGATRAASLDQLIASALPRLDALLAEGVTTLEIKSGYGLTIESERRLLQ
AARALGRRRPVDVVTTFLGAHALPPEFSGDGNGYIDHLCASMLPALAAEGLVDAVDVFCETIAFSLAQATRVFEAARGLG
LPVKVHAEQLGLLGGAALAAGFGALSADHVEYLDEAGVRALAAAGTVAVLLPGAFHMLRETQRPPVDALRRFGVAIAIAT
DCNPGTSPVTSPLLMLNMACVLFRLTPEEALAGLTRNGAKALGLSDRGVLAPGLRADFALWDIGHPAELAYALGLNPCHA
VVRAGEPRPPRAPF
>Mature_413_residues
AQAPWDSLWLNGSLATMAAGGAAYGAIEDGAIAVADGRLVFVGRRADLPPGAEDRAASLHDLGGRWVTPGLIDCHTHLVY
AGSRAREFELRLQGASYEEIARAGGGIVSTVGATRAASLDQLIASALPRLDALLAEGVTTLEIKSGYGLTIESERRLLQA
ARALGRRRPVDVVTTFLGAHALPPEFSGDGNGYIDHLCASMLPALAAEGLVDAVDVFCETIAFSLAQATRVFEAARGLGL
PVKVHAEQLGLLGGAALAAGFGALSADHVEYLDEAGVRALAAAGTVAVLLPGAFHMLRETQRPPVDALRRFGVAIAIATD
CNPGTSPVTSPLLMLNMACVLFRLTPEEALAGLTRNGAKALGLSDRGVLAPGLRADFALWDIGHPAELAYALGLNPCHAV
VRAGEPRPPRAPF

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=339, Percent_Identity=35.9882005899705, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17555004, Length=365, Percent_Identity=33.6986301369863, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_RHORT (Q2RUU1)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426391.1
- HSSP:   Q8U8Z6
- ProteinModelPortal:   Q2RUU1
- SMR:   Q2RUU1
- STRING:   Q2RUU1
- GeneID:   3833611
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1303
- NMPDR:   fig|1085.1.peg.3063
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   RRUB269796:RRU_A1303-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 42975; Mature: 42844

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: BINDING 85-85 BINDING 98-98 BINDING 148-148 BINDING 181-181 BINDING 249-249

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAPWDSLWLNGSLATMAAGGAAYGAIEDGAIAVADGRLVFVGRRADLPPGAEDRAASL
CCCCCCCCEEECCCHHHHHCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCHHHHHH
HDLGGRWVTPGLIDCHTHLVYAGSRAREFELRLQGASYEEIARAGGGIVSTVGATRAASL
HHCCCCCCCCCHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHCCCCEEEHHCCHHHHHH
DQLIASALPRLDALLAEGVTTLEIKSGYGLTIESERRLLQAARALGRRRPVDVVTTFLGA
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHC
HALPPEFSGDGNGYIDHLCASMLPALAAEGLVDAVDVFCETIAFSLAQATRVFEAARGLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVKVHAEQLGLLGGAALAAGFGALSADHVEYLDEAGVRALAAAGTVAVLLPGAFHMLRE
CCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHEEHHHHHHHHHHH
TQRPPVDALRRFGVAIAIATDCNPGTSPVTSPLLMLNMACVLFRLTPEEALAGLTRNGAK
CCCCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
ALGLSDRGVLAPGLRADFALWDIGHPAELAYALGLNPCHAVVRAGEPRPPRAPF
EECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AQAPWDSLWLNGSLATMAAGGAAYGAIEDGAIAVADGRLVFVGRRADLPPGAEDRAASL
CCCCCCCEEECCCHHHHHCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCHHHHHH
HDLGGRWVTPGLIDCHTHLVYAGSRAREFELRLQGASYEEIARAGGGIVSTVGATRAASL
HHCCCCCCCCCHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHCCCCEEEHHCCHHHHHH
DQLIASALPRLDALLAEGVTTLEIKSGYGLTIESERRLLQAARALGRRRPVDVVTTFLGA
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHC
HALPPEFSGDGNGYIDHLCASMLPALAAEGLVDAVDVFCETIAFSLAQATRVFEAARGLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVKVHAEQLGLLGGAALAAGFGALSADHVEYLDEAGVRALAAAGTVAVLLPGAFHMLRE
CCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHEEHHHHHHHHHHH
TQRPPVDALRRFGVAIAIATDCNPGTSPVTSPLLMLNMACVLFRLTPEEALAGLTRNGAK
CCCCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
ALGLSDRGVLAPGLRADFALWDIGHPAELAYALGLNPCHAVVRAGEPRPPRAPF
EECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA