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The map label for this gene is glcD [H]

Identifier: 83592635

GI number: 83592635

Start: 1532308

End: 1533678

Strand: Direct

Name: glcD [H]

Synonym: Rru_A1299

Alternate gene names: 83592635

Gene position: 1532308-1533678 (Clockwise)

Preceding gene: 83592634

Following gene: 83592639

Centisome position: 35.2

GC content: 66.59

Gene sequence:

>1371_bases
ATGTCCCTGTCCGCTGCCGCCCTGTCTGATCTGTCCGCCCTATTGGGAGAGCGGCTGGTGCTGTCACAGGCGGTGCGCGA
CCACCACGGTCATGGCGAGTCCTGGCATGGCGTTCAGGCGCCCGAGGCCGTCGCCTTTCTGAAAACCGCTGAGGAAGCCC
AGGCGGTGGTGGCGCTGTGCGCCGCCCATGGCGTGCCGATGGTGCCCTTTGGCGCCGGGTCTTCGATGGAGGGGCAGGTT
CAGGCCACGGCCGGTGGCTTGTGCCTGGATATGAGCGCGATGACGGCGATCCTGGCGGTGCGCCCCGAGGATATGGATTG
CACCGTCCAGCCCGGGGTGACGCGCCAGCAATTGAACGAGCATCTGCGGGCTCAAGGGTTGTTCTTCCCCATCGATCCCG
GGGCCGAGGCGACCCTGGGCGGCATGGCGTCGACCCGGGCCTCGGGCACCAATGCCGTGCGCTACGGCACCATGCGCGAC
GTGGTGCTGGCGCTTGAGGTGGTGTTGGCCGATGGCCGGCGTCTTCGCACCGGCAGCCGGGCGCGCAAATCGGCGGCCGG
TTATGATCTGACCCGGCTGATGATCGGCGCCGAGGGAACCCTGGGGCTGATCACCGAACTGACCCTGCGGCTGTTCCCGA
TCCCGGAAAAACAGGCTGCGGCCATTTGTTCGTTTCCCAGCCTGGAGCAGGCGGTGGCCTGCGTCGTGGCGACCGCGCAA
TGCGGGGTGGGGATGTCGCGGATTGAATTCGCCGATCGTTTGCAGATGCGGGCGATCAACGCCTATTCCCACACCAACTT
TCCCGAAAGCCCGATGCTGTTCCTGGAATTCGCCGGATCGGCGGCGGCCGTCGAGGCCGAGATCGCCACCGTGCGCGCCT
TGGCCGATGAGCATGGCGGCGGTGGCTTCGCCTGGGCCGAAAGCGAAGAGGACCGCCGCGCCCTGTGGAAGGCCCGCCAC
AGCGCCGCTTATGCCGCGCTTGCCCTGCGTCCGGGGTGCAAGGGGCTGGCGACCGATGTCTGCGTGCCGATTTCTCGCCT
GGTCGACTGCTTGGTCGAAACCCAGAAGGATCTGGCGACCAGCCCCTTGCCGGCGCCGATCGCCGGCCATGTCGGCGATG
GCAATTTCCATCTGATGATCGTTTTTGATCCCGCCGATCCGGCCGAGGTGGCCGAAGCCAAACGCCTCGACGATGCCCTT
GGTCGCCGCGCCCTGGCGATGGAGGGGACCTGCACCGGCGAACATGGCATCGGCCTGGGCAAACGCGGCCTGTTGGCCCT
TGAGGCTGGCGAGGGCGTCGATGTCATGCGTCAGATCAAGGCGGCGCTTGATCCAAAGGGCCTGATGAACCCGGGAAAGA
TTTTCCTGTAA

Upstream 100 bases:

>100_bases
CGCGCGCCGTCTTCCACGAAAGCCCCGAACCCCGCCTGCGCCAGTTCCTTCAGACCTACCATGAGCGCAATAGTTTTTAA
GCTTTTCAAGGTTTTATTCC

Downstream 100 bases:

>100_bases
CCCTTTTAGGGCCGCCACGCGATCAGTTGGTCCAGCAGGCGGTGGAGCAGCGGGCGCAGGCGATCGGCGCGCTCGGGCAG
ATAGGCGTAGCTTTCCTCGT

Product: FAD linked oxidase-like

Products: pyruvate; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSLSAAALSDLSALLGERLVLSQAVRDHHGHGESWHGVQAPEAVAFLKTAEEAQAVVALCAAHGVPMVPFGAGSSMEGQV
QATAGGLCLDMSAMTAILAVRPEDMDCTVQPGVTRQQLNEHLRAQGLFFPIDPGAEATLGGMASTRASGTNAVRYGTMRD
VVLALEVVLADGRRLRTGSRARKSAAGYDLTRLMIGAEGTLGLITELTLRLFPIPEKQAAAICSFPSLEQAVACVVATAQ
CGVGMSRIEFADRLQMRAINAYSHTNFPESPMLFLEFAGSAAAVEAEIATVRALADEHGGGGFAWAESEEDRRALWKARH
SAAYAALALRPGCKGLATDVCVPISRLVDCLVETQKDLATSPLPAPIAGHVGDGNFHLMIVFDPADPAEVAEAKRLDDAL
GRRALAMEGTCTGEHGIGLGKRGLLALEAGEGVDVMRQIKAALDPKGLMNPGKIFL

Sequences:

>Translated_456_residues
MSLSAAALSDLSALLGERLVLSQAVRDHHGHGESWHGVQAPEAVAFLKTAEEAQAVVALCAAHGVPMVPFGAGSSMEGQV
QATAGGLCLDMSAMTAILAVRPEDMDCTVQPGVTRQQLNEHLRAQGLFFPIDPGAEATLGGMASTRASGTNAVRYGTMRD
VVLALEVVLADGRRLRTGSRARKSAAGYDLTRLMIGAEGTLGLITELTLRLFPIPEKQAAAICSFPSLEQAVACVVATAQ
CGVGMSRIEFADRLQMRAINAYSHTNFPESPMLFLEFAGSAAAVEAEIATVRALADEHGGGGFAWAESEEDRRALWKARH
SAAYAALALRPGCKGLATDVCVPISRLVDCLVETQKDLATSPLPAPIAGHVGDGNFHLMIVFDPADPAEVAEAKRLDDAL
GRRALAMEGTCTGEHGIGLGKRGLLALEAGEGVDVMRQIKAALDPKGLMNPGKIFL
>Mature_455_residues
SLSAAALSDLSALLGERLVLSQAVRDHHGHGESWHGVQAPEAVAFLKTAEEAQAVVALCAAHGVPMVPFGAGSSMEGQVQ
ATAGGLCLDMSAMTAILAVRPEDMDCTVQPGVTRQQLNEHLRAQGLFFPIDPGAEATLGGMASTRASGTNAVRYGTMRDV
VLALEVVLADGRRLRTGSRARKSAAGYDLTRLMIGAEGTLGLITELTLRLFPIPEKQAAAICSFPSLEQAVACVVATAQC
GVGMSRIEFADRLQMRAINAYSHTNFPESPMLFLEFAGSAAAVEAEIATVRALADEHGGGGFAWAESEEDRRALWKARHS
AAYAALALRPGCKGLATDVCVPISRLVDCLVETQKDLATSPLPAPIAGHVGDGNFHLMIVFDPADPAEVAEAKRLDDALG
RRALAMEGTCTGEHGIGLGKRGLLALEAGEGVDVMRQIKAALDPKGLMNPGKIFL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=444, Percent_Identity=53.6036036036036, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI37595754, Length=467, Percent_Identity=50.9635974304068, Blast_Score=464, Evalue=1e-131,
Organism=Homo sapiens, GI119964728, Length=428, Percent_Identity=28.0373831775701, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4501993, Length=454, Percent_Identity=24.4493392070485, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1789351, Length=423, Percent_Identity=30.2600472813239, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787977, Length=497, Percent_Identity=27.364185110664, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI48994907, Length=232, Percent_Identity=34.051724137931, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994914, Length=133, Percent_Identity=33.8345864661654, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71992373, Length=456, Percent_Identity=44.9561403508772, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71992381, Length=456, Percent_Identity=44.078947368421, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71992392, Length=379, Percent_Identity=47.2295514511873, Blast_Score=358, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17556096, Length=481, Percent_Identity=23.7006237006237, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17534361, Length=464, Percent_Identity=26.0775862068966, Blast_Score=112, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320027, Length=467, Percent_Identity=37.9014989293362, Blast_Score=319, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6320023, Length=475, Percent_Identity=26.9473684210526, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320764, Length=468, Percent_Identity=25.2136752136752, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI18921117, Length=479, Percent_Identity=26.3048016701461, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24639277, Length=479, Percent_Identity=26.3048016701461, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24639275, Length=479, Percent_Identity=26.3048016701461, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653753, Length=206, Percent_Identity=33.9805825242718, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.2.4

Molecular weight: Translated: 47809; Mature: 47678

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSAAALSDLSALLGERLVLSQAVRDHHGHGESWHGVQAPEAVAFLKTAEEAQAVVALC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AAHGVPMVPFGAGSSMEGQVQATAGGLCLDMSAMTAILAVRPEDMDCTVQPGVTRQQLNE
HHCCCCEEECCCCCCCCCEEEECCCCEEEEHHHHHHHHEECCCCCCEEECCCCCHHHHHH
HLRAQGLFFPIDPGAEATLGGMASTRASGTNAVRYGTMRDVVLALEVVLADGRRLRTGSR
HHHHCCCEEECCCCCCCHHCCCHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEECCCCH
ARKSAAGYDLTRLMIGAEGTLGLITELTLRLFPIPEKQAAAICSFPSLEQAVACVVATAQ
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHH
CGVGMSRIEFADRLQMRAINAYSHTNFPESPMLFLEFAGSAAAVEAEIATVRALADEHGG
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
GGFAWAESEEDRRALWKARHSAAYAALALRPGCKGLATDVCVPISRLVDCLVETQKDLAT
CCEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SPLPAPIAGHVGDGNFHLMIVFDPADPAEVAEAKRLDDALGRRALAMEGTCTGEHGIGLG
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
KRGLLALEAGEGVDVMRQIKAALDPKGLMNPGKIFL
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLSAAALSDLSALLGERLVLSQAVRDHHGHGESWHGVQAPEAVAFLKTAEEAQAVVALC
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AAHGVPMVPFGAGSSMEGQVQATAGGLCLDMSAMTAILAVRPEDMDCTVQPGVTRQQLNE
HHCCCCEEECCCCCCCCCEEEECCCCEEEEHHHHHHHHEECCCCCCEEECCCCCHHHHHH
HLRAQGLFFPIDPGAEATLGGMASTRASGTNAVRYGTMRDVVLALEVVLADGRRLRTGSR
HHHHCCCEEECCCCCCCHHCCCHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEECCCCH
ARKSAAGYDLTRLMIGAEGTLGLITELTLRLFPIPEKQAAAICSFPSLEQAVACVVATAQ
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHH
CGVGMSRIEFADRLQMRAINAYSHTNFPESPMLFLEFAGSAAAVEAEIATVRALADEHGG
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
GGFAWAESEEDRRALWKARHSAAYAALALRPGCKGLATDVCVPISRLVDCLVETQKDLAT
CCEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SPLPAPIAGHVGDGNFHLMIVFDPADPAEVAEAKRLDDALGRRALAMEGTCTGEHGIGLG
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
KRGLLALEAGEGVDVMRQIKAALDPKGLMNPGKIFL
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-lactate; ferricytochrome c

Specific reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]