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The map label for this gene is rpfC [H]

Identifier: 83592613

GI number: 83592613

Start: 1502001

End: 1504436

Strand: Direct

Name: rpfC [H]

Synonym: Rru_A1277

Alternate gene names: 83592613

Gene position: 1502001-1504436 (Clockwise)

Preceding gene: 83592608

Following gene: 83592614

Centisome position: 34.51

GC content: 66.17

Gene sequence:

>2436_bases
ATGATTGCGCTTGAAAAATTGCTGCGCGAGAACGAGGACTGGCTGGTTCGCCGTGTCATCGACTACGCCCGGGAGCAGGG
GTATATGGCTTATACCTCGACTCTGGAAGAGGCGTGGCGGGCGGGGATGGTCGGGTTGATCGACGCCTTCCTGGCCGCCG
AGGCCGATGGCACGCCGGCCGCGCCGCCGCGGGCGTCGCTTTCCTATACGGAAGATCCCGTCGCCGGCTATGGCATCGAG
ACCGCCAATCGTCACCGCGCCCGGGGGATCCCGCTGGCGCTGTTTCTCGGCCTGCTGAAATACAACCGTCGCGCCCTGCT
TGATCTGGCGGCGCGCGATCCCCGCCCGGCGGCTGATCAGGCCGAGATCAAGAACCGGATCGACAATTACTTCGACCGGG
TGGAGCTGGGGTTGTGCGCGGCGTGGTCGCGTTTCGAGCGCGAGCAGGAGGTGGGAAAGCTGCGCGAGCGTAATCGCGAT
CTGGTCAATGAAAAGAACAAATATCTGACGGCTTTCGAAAGCCTGACCGATCCGGTTTTCCTGATCAACGACGCGGGCGG
CCTGGAAAACCTCAATCGCAGCGCCGGAATTCTGATCGGCTTTGGTCCCAGCCCCGGTGCGGGCTATTACGGCAGCGGCA
TTCCCCCCAGCGCCCAACGTCTGGTTGACGATCTGCTGGCGCGGTTTGCCCAGAAAGCCGCCGAGGCCGAAGGCGCCGAG
AGCGATCGCATCGATTACCGGATGGACACGGTCGAGGGCCCGCGCGACTTCGAGGTGCGCCGTCAGGCCATGCTCGATGT
CAGCGAGCGCTACAGCGGGCAGGTGCTGATCTTTTCCGATATCACCGCCTATAAGCGGGCCTCCGACCGCGCCGAGGAGG
CCAATCAGGCCAAATCGACCTTTCTGGCGACGATGAGCCACGAGATCCGCACGCCGATCAACGGCATCCTCGGCCTTTCG
ACCCTGATGCGCGACGAGTTGCGCGACGAGCGCCTGCGCCACCACGCCGACGCCATCGCCCTGTCGGCCGAGATGCTGCT
GTCGATGGTCAACGACGTGCTCGATTTCACCAAGATCGAGGCCGGCATCTTGGATCTCGATCCGGTCGATTTCTCGGTCG
AGGAATTGCTCAACGGCGTCTTCGCCCTGGTCGCCCCCTCGGCCCACCGCAAGGGGCTAGAGGTCTATCGCAGCGTTTCG
CCCGCCGTTCCCGAGCGGTTGCACGGCGATCTGGCCAAGCTGCGTCAGGTGCTGCTGAATTTGTTCTCCAACGCCGTGAA
GTTCACCCATGCCGGGGCGCTGTCGATCCATATCGACCGCCTTGCCGAGGCGCCCGAGGGCAAGGTGATCCTTCATATCA
CCGTCGATGATACGGGCATCGGCATCGCGCCCTCGGCGCTCAAGGCGATTTTCGAGCCCTTCGCCCAGGCCGACGGATCG
ATCTCGCGGCGCTTTGGCGGCACCGGCATGGGCTTGGCGATCAATCGCCGGCTGGCCGAGGTCATGGGCGGCGAAGTCTG
GGCCGAAAGCCGCGAGGGCGAGGGCAGCCGCTTTCACGTCACCGCCCTGCTTGAAGCGGCACGCCTGCCGCCGCCGCCGC
CCGATACGGCCAATGGCCAGCCCCCGGCGTTTTTGGCCGATCGGCCGCTTTCGGTGCTGGTCGTCGATGACAACGACGTC
AACCTGATGGTGGCCGAGGGGTTCCTGAAACGCTTCGGCCATGACGTCGTCTTGGCGCGCAATGGTCGCGAGGCCCGCGC
CCTGCTTGAACACCGGCGCTTCGACGCCGCCTTGCTTGATATCAATCTTCCCGATGCCAACGGCCTGGATCTGCTGGCCG
AGGTGCGGCGCCACGAGGCGGCGGTCGGTTTGCGTTCCATGCCGATCATCGTGCTGTCGGCCCATGTGATGCAGGCCGAT
ATCGCCCGCTCGGCCCGTTTGGACGTGCGGTTCTTGGGCAAACCCTTCAACCCGGAGCGCCTGCGCCGCATGCTGCGCGA
CCTGACCCGTCAGGACGACGACCCGAGGGCGGGGGAGGGCGACGGCGAGGGGCCGGTCGCCGAGGATTTCACCGCCGGAC
CGGTGCTGGTCGATCCCGCCGTGCTGCGCGGCCATGTGGAGATGCTGGGGGCGACGGCGGCGGGCAAGATCCTGGCCGCC
TTCCACGGCTCGGCGCCGCGCACCCTGGCCACGCTGTGCTCCCATGTCGAGGCCGGCCGGATCGCCGAGGCGGAGGACGA
CGCCCATCGCCTGAAAAGCGCATCGGCCAATCTTGGCCTGGAGTGCCTGCGTCGGCGGGCGGCCGAACTGGAAGCCGCCT
GCGGCCAGGGCGAAAGCGCCGCGGTCGGCGTGCTGGTCGAGCATCTGCCGACGCTGTTTGACTCGTCGCTGCGCGATCTT
GATCGGCTGTGGGACGAGATCACCGCCAAGGGGTGA

Upstream 100 bases:

>100_bases
GCTCTGACCGCTATGGGAAGTCAAGCGGCCATCGGTCGACGCTGGTGCGCCGGGGGCGTATGGCTGCTAAGCTGGGCTTT
GGCCCGCAAAGGATTTCGCC

Downstream 100 bases:

>100_bases
CGAGCGATGACTGATTTTGGTAAGGGCATGATCAGGCGGCGAACTGGGGGGCGGACCCCTCGATGCCGTACCGGAAGCGG
CCTTGGGGGACGCCGCTTAG

Product: Hpt sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MIALEKLLRENEDWLVRRVIDYAREQGYMAYTSTLEEAWRAGMVGLIDAFLAAEADGTPAAPPRASLSYTEDPVAGYGIE
TANRHRARGIPLALFLGLLKYNRRALLDLAARDPRPAADQAEIKNRIDNYFDRVELGLCAAWSRFEREQEVGKLRERNRD
LVNEKNKYLTAFESLTDPVFLINDAGGLENLNRSAGILIGFGPSPGAGYYGSGIPPSAQRLVDDLLARFAQKAAEAEGAE
SDRIDYRMDTVEGPRDFEVRRQAMLDVSERYSGQVLIFSDITAYKRASDRAEEANQAKSTFLATMSHEIRTPINGILGLS
TLMRDELRDERLRHHADAIALSAEMLLSMVNDVLDFTKIEAGILDLDPVDFSVEELLNGVFALVAPSAHRKGLEVYRSVS
PAVPERLHGDLAKLRQVLLNLFSNAVKFTHAGALSIHIDRLAEAPEGKVILHITVDDTGIGIAPSALKAIFEPFAQADGS
ISRRFGGTGMGLAINRRLAEVMGGEVWAESREGEGSRFHVTALLEAARLPPPPPDTANGQPPAFLADRPLSVLVVDDNDV
NLMVAEGFLKRFGHDVVLARNGREARALLEHRRFDAALLDINLPDANGLDLLAEVRRHEAAVGLRSMPIIVLSAHVMQAD
IARSARLDVRFLGKPFNPERLRRMLRDLTRQDDDPRAGEGDGEGPVAEDFTAGPVLVDPAVLRGHVEMLGATAAGKILAA
FHGSAPRTLATLCSHVEAGRIAEAEDDAHRLKSASANLGLECLRRRAAELEAACGQGESAAVGVLVEHLPTLFDSSLRDL
DRLWDEITAKG

Sequences:

>Translated_811_residues
MIALEKLLRENEDWLVRRVIDYAREQGYMAYTSTLEEAWRAGMVGLIDAFLAAEADGTPAAPPRASLSYTEDPVAGYGIE
TANRHRARGIPLALFLGLLKYNRRALLDLAARDPRPAADQAEIKNRIDNYFDRVELGLCAAWSRFEREQEVGKLRERNRD
LVNEKNKYLTAFESLTDPVFLINDAGGLENLNRSAGILIGFGPSPGAGYYGSGIPPSAQRLVDDLLARFAQKAAEAEGAE
SDRIDYRMDTVEGPRDFEVRRQAMLDVSERYSGQVLIFSDITAYKRASDRAEEANQAKSTFLATMSHEIRTPINGILGLS
TLMRDELRDERLRHHADAIALSAEMLLSMVNDVLDFTKIEAGILDLDPVDFSVEELLNGVFALVAPSAHRKGLEVYRSVS
PAVPERLHGDLAKLRQVLLNLFSNAVKFTHAGALSIHIDRLAEAPEGKVILHITVDDTGIGIAPSALKAIFEPFAQADGS
ISRRFGGTGMGLAINRRLAEVMGGEVWAESREGEGSRFHVTALLEAARLPPPPPDTANGQPPAFLADRPLSVLVVDDNDV
NLMVAEGFLKRFGHDVVLARNGREARALLEHRRFDAALLDINLPDANGLDLLAEVRRHEAAVGLRSMPIIVLSAHVMQAD
IARSARLDVRFLGKPFNPERLRRMLRDLTRQDDDPRAGEGDGEGPVAEDFTAGPVLVDPAVLRGHVEMLGATAAGKILAA
FHGSAPRTLATLCSHVEAGRIAEAEDDAHRLKSASANLGLECLRRRAAELEAACGQGESAAVGVLVEHLPTLFDSSLRDL
DRLWDEITAKG
>Mature_811_residues
MIALEKLLRENEDWLVRRVIDYAREQGYMAYTSTLEEAWRAGMVGLIDAFLAAEADGTPAAPPRASLSYTEDPVAGYGIE
TANRHRARGIPLALFLGLLKYNRRALLDLAARDPRPAADQAEIKNRIDNYFDRVELGLCAAWSRFEREQEVGKLRERNRD
LVNEKNKYLTAFESLTDPVFLINDAGGLENLNRSAGILIGFGPSPGAGYYGSGIPPSAQRLVDDLLARFAQKAAEAEGAE
SDRIDYRMDTVEGPRDFEVRRQAMLDVSERYSGQVLIFSDITAYKRASDRAEEANQAKSTFLATMSHEIRTPINGILGLS
TLMRDELRDERLRHHADAIALSAEMLLSMVNDVLDFTKIEAGILDLDPVDFSVEELLNGVFALVAPSAHRKGLEVYRSVS
PAVPERLHGDLAKLRQVLLNLFSNAVKFTHAGALSIHIDRLAEAPEGKVILHITVDDTGIGIAPSALKAIFEPFAQADGS
ISRRFGGTGMGLAINRRLAEVMGGEVWAESREGEGSRFHVTALLEAARLPPPPPDTANGQPPAFLADRPLSVLVVDDNDV
NLMVAEGFLKRFGHDVVLARNGREARALLEHRRFDAALLDINLPDANGLDLLAEVRRHEAAVGLRSMPIIVLSAHVMQAD
IARSARLDVRFLGKPFNPERLRRMLRDLTRQDDDPRAGEGDGEGPVAEDFTAGPVLVDPAVLRGHVEMLGATAAGKILAA
FHGSAPRTLATLCSHVEAGRIAEAEDDAHRLKSASANLGLECLRRRAAELEAACGQGESAAVGVLVEHLPTLFDSSLRDL
DRLWDEITAKG

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=658, Percent_Identity=29.483282674772, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789149, Length=285, Percent_Identity=40, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI87081816, Length=500, Percent_Identity=31.4, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=36.5942028985507, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=29.5918367346939, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=30.0813008130081, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=31.651376146789, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=27.0916334661355, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=368, Percent_Identity=25.5434782608696, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=29.7674418604651, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=26.6129032258064, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=27.7056277056277, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788545, Length=190, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=8e-11,
Organism=Escherichia coli, GI1790300, Length=354, Percent_Identity=24.5762711864407, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=92, Percent_Identity=44.5652173913043, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88630; Mature: 88630

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALEKLLRENEDWLVRRVIDYAREQGYMAYTSTLEEAWRAGMVGLIDAFLAAEADGTPA
CCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
APPRASLSYTEDPVAGYGIETANRHRARGIPLALFLGLLKYNRRALLDLAARDPRPAADQ
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCHH
AEIKNRIDNYFDRVELGLCAAWSRFEREQEVGKLRERNRDLVNEKNKYLTAFESLTDPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LINDAGGLENLNRSAGILIGFGPSPGAGYYGSGIPPSAQRLVDDLLARFAQKAAEAEGAE
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
SDRIDYRMDTVEGPRDFEVRRQAMLDVSERYSGQVLIFSDITAYKRASDRAEEANQAKST
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
FLATMSHEIRTPINGILGLSTLMRDELRDERLRHHADAIALSAEMLLSMVNDVLDFTKIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGILDLDPVDFSVEELLNGVFALVAPSAHRKGLEVYRSVSPAVPERLHGDLAKLRQVLLN
CCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LFSNAVKFTHAGALSIHIDRLAEAPEGKVILHITVDDTGIGIAPSALKAIFEPFAQADGS
HHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
ISRRFGGTGMGLAINRRLAEVMGGEVWAESREGEGSRFHVTALLEAARLPPPPPDTANGQ
HHHHCCCCCCCHHHHHHHHHHHCCHHEECCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCC
PPAFLADRPLSVLVVDDNDVNLMVAEGFLKRFGHDVVLARNGREARALLEHRRFDAALLD
CCCEECCCCEEEEEECCCCCEEEEHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEEEE
INLPDANGLDLLAEVRRHEAAVGLRSMPIIVLSAHVMQADIARSARLDVRFLGKPFNPER
EECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHH
LRRMLRDLTRQDDDPRAGEGDGEGPVAEDFTAGPVLVDPAVLRGHVEMLGATAAGKILAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FHGSAPRTLATLCSHVEAGRIAEAEDDAHRLKSASANLGLECLRRRAAELEAACGQGESA
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCH
AVGVLVEHLPTLFDSSLRDLDRLWDEITAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIALEKLLRENEDWLVRRVIDYAREQGYMAYTSTLEEAWRAGMVGLIDAFLAAEADGTPA
CCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
APPRASLSYTEDPVAGYGIETANRHRARGIPLALFLGLLKYNRRALLDLAARDPRPAADQ
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCHH
AEIKNRIDNYFDRVELGLCAAWSRFEREQEVGKLRERNRDLVNEKNKYLTAFESLTDPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LINDAGGLENLNRSAGILIGFGPSPGAGYYGSGIPPSAQRLVDDLLARFAQKAAEAEGAE
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
SDRIDYRMDTVEGPRDFEVRRQAMLDVSERYSGQVLIFSDITAYKRASDRAEEANQAKST
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
FLATMSHEIRTPINGILGLSTLMRDELRDERLRHHADAIALSAEMLLSMVNDVLDFTKIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGILDLDPVDFSVEELLNGVFALVAPSAHRKGLEVYRSVSPAVPERLHGDLAKLRQVLLN
CCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LFSNAVKFTHAGALSIHIDRLAEAPEGKVILHITVDDTGIGIAPSALKAIFEPFAQADGS
HHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
ISRRFGGTGMGLAINRRLAEVMGGEVWAESREGEGSRFHVTALLEAARLPPPPPDTANGQ
HHHHCCCCCCCHHHHHHHHHHHCCHHEECCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCC
PPAFLADRPLSVLVVDDNDVNLMVAEGFLKRFGHDVVLARNGREARALLEHRRFDAALLD
CCCEECCCCEEEEEECCCCCEEEEHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEEEE
INLPDANGLDLLAEVRRHEAAVGLRSMPIIVLSAHVMQADIARSARLDVRFLGKPFNPER
EECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHH
LRRMLRDLTRQDDDPRAGEGDGEGPVAEDFTAGPVLVDPAVLRGHVEMLGATAAGKILAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FHGSAPRTLATLCSHVEAGRIAEAEDDAHRLKSASANLGLECLRRRAAELEAACGQGESA
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCH
AVGVLVEHLPTLFDSSLRDLDRLWDEITAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]