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The map label for this gene is yegE [H]

Identifier: 83592608

GI number: 83592608

Start: 1495736

End: 1497634

Strand: Direct

Name: yegE [H]

Synonym: Rru_A1272

Alternate gene names: 83592608

Gene position: 1495736-1497634 (Clockwise)

Preceding gene: 83592605

Following gene: 83592613

Centisome position: 34.36

GC content: 61.93

Gene sequence:

>1899_bases
ATGAAACGCGTTCCATGGGTGGTCGGTGGCCTGATCCTGATCATGGCATATAATGCGGCGCTCGGGACCTTGGCTTATTG
GCAGCGGCGCGACATTATCGATGAATCCTTGCGGGAAGCGGTTGTCGTCGCCGATATTCTTGTCCGCGAGGTCGAAGCCA
ACCTGGATCGGATTGATCGTACTTTATCGGGGCTGACCGAGGTCTTGCGGGCTTATCCGAGCGCGATCGATGTCCATGAT
CCGTTTACCCACCGCCTGCTGTTGCGTCGTCACGCCATCACGCCGTCTTTGGCGGCGCTGTTTCTGATCGGTGGCGACGG
CAGGCTGCGCAACGCCTCGCTGACGGATAAGGTCTCGGAAATCGATGTGTCGGGCGAAGATTATTTCGCCTTCCATCTGT
CCAATGTGGACGATGAGTTTTTCATCGGCGCGGTCACCACCAATCGTCTCGATAAAAGCTGGGTCATCCCGGTGAGCCGG
GCGGTGAGGGATTCCTTTGGTCGGCTGACCGGGGTGGTCGCCGCGACGATCACCACCGATTCCATCGATCAGATGATCCA
CTCCCATCAGCTTTCCGAAGGTTTCGCGGTGACGATCACCCAGCGCGACGCCGGGATGATCGGCTGCCTTGGCTTTACGC
GGTGTTGGGGCGAGGGCGCGCCGCACAGGGGCGACGAGGGGCTTGCTGAAAGCGGAGGCAGCGGCGAGGAGGTCCATTAC
CTGCCCAATGGGCCGGGAGTCGGCGCCTTCCTTCGGGGTCCGACTTACGGCGTCGAGGTGACCGTTCAGGCCAGCGATCG
GACGCTTCTTCAGCCTTGGCGGGAAAAACTGGCCTTTATCCTGGTGCTGCAGGTCTTTGGCACCCTCGGCCTCGGGTTCG
GCATCACCTCGCTTTATTATCAGATGCATCATCGCCGCGTATCGCTGTTGGATCTGGAACGCGCCAATGCGTCGCTGGAA
AGCAAGGTGGCCGAGCGCACGCGGCAATTGGCCGAAGGCGAGGAGCGGATGCGCGGCTTCATCATGGCGGCCCGCGACGC
CGTGGTCATCATCGATCAAAAGGGCATCATCAGCGAATTCAACCCCTCGGCGACCGAACTATTCGGCTATGACGTCGAGG
AGGTGCGCGGTCAAAGCGTCAATATGCTGATGCCCGCGACCTACGCGCGCGATCACGACGGCCACCTGCGCAAGGGCAAG
CCCTCCGGCCAGCGCGCCATTGGGCGGGGGCGCGAAATGATCGGCCGACGCAAGAACGGCAGCGAATTTCCGATCGAATT
GACGGTCGGCACCCAGTCCTTCGATGGAACCCGGGTTCATATCGGGGTGATCCGCGATATCACCGAACGCAAGGCCACCG
AGGAAACCCTGCGGCGGCTGGCCAATATCGACGGTTTGACGGGGGTGCTCAATCGCCGCTCCTTCACCGAGGAAAGCGAA
TTATTGTTGTCGCTGGCCAACCGCCATGGCCGCCGTCTGTCGATGATGATCGTCGATGCCGATCACTTCAAAGGGGTCAA
CGATACCTATGGTCACGACGCCGGCGACAGGGTGCTGAAGGCCCTGACCGGGGAAATCGCCGGCGTCTTGCGCAAAACCG
ATCTGCTGGGACGCATCGGCGGCGAGGAATTCGCCATCCTGCTGCCCGAAACCGACCAGGAGGGCGCCGAGGGACTGGCT
TGGCGGGTGGTTCTAGCCATTCGCGCCCTGGAGGTTCCCTTGCCCGAGGGCGGGGTGTTGAAGGTCACCGTCAGCGTGGG
GGTCAGTTGCCGGAACACCGAGGCGGCGACCTTCGATTGGATGCTCAAGGAGGCCGACACGGCCCTGTACGCCGCCAAGC
ATGGCGGCCGGGATCGCGTGGCCTGCTTTGGGCAAACCCAATCGGTGGCCAGATCCTGA

Upstream 100 bases:

>100_bases
AGAAAAAGATGGTCGCCCCCCTCTCCTTATTGTCCAGTTTTCGGCTCTCCGGCGAGGGTGGTTTGGAAGGTCTCGGTGGT
CAGTGGCCGTCGGAGGTGGA

Downstream 100 bases:

>100_bases
AGGAGGAAGGGCGGGCTGGAGCGGCTTTCAGGCGGCGAAGGGGCGCAGGCGGTGGAGGGCTTCAAGCACGGCGTCGGGCC
GTTCGTCCATCACCATGTGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MKRVPWVVGGLILIMAYNAALGTLAYWQRRDIIDESLREAVVVADILVREVEANLDRIDRTLSGLTEVLRAYPSAIDVHD
PFTHRLLLRRHAITPSLAALFLIGGDGRLRNASLTDKVSEIDVSGEDYFAFHLSNVDDEFFIGAVTTNRLDKSWVIPVSR
AVRDSFGRLTGVVAATITTDSIDQMIHSHQLSEGFAVTITQRDAGMIGCLGFTRCWGEGAPHRGDEGLAESGGSGEEVHY
LPNGPGVGAFLRGPTYGVEVTVQASDRTLLQPWREKLAFILVLQVFGTLGLGFGITSLYYQMHHRRVSLLDLERANASLE
SKVAERTRQLAEGEERMRGFIMAARDAVVIIDQKGIISEFNPSATELFGYDVEEVRGQSVNMLMPATYARDHDGHLRKGK
PSGQRAIGRGREMIGRRKNGSEFPIELTVGTQSFDGTRVHIGVIRDITERKATEETLRRLANIDGLTGVLNRRSFTEESE
LLLSLANRHGRRLSMMIVDADHFKGVNDTYGHDAGDRVLKALTGEIAGVLRKTDLLGRIGGEEFAILLPETDQEGAEGLA
WRVVLAIRALEVPLPEGGVLKVTVSVGVSCRNTEAATFDWMLKEADTALYAAKHGGRDRVACFGQTQSVARS

Sequences:

>Translated_632_residues
MKRVPWVVGGLILIMAYNAALGTLAYWQRRDIIDESLREAVVVADILVREVEANLDRIDRTLSGLTEVLRAYPSAIDVHD
PFTHRLLLRRHAITPSLAALFLIGGDGRLRNASLTDKVSEIDVSGEDYFAFHLSNVDDEFFIGAVTTNRLDKSWVIPVSR
AVRDSFGRLTGVVAATITTDSIDQMIHSHQLSEGFAVTITQRDAGMIGCLGFTRCWGEGAPHRGDEGLAESGGSGEEVHY
LPNGPGVGAFLRGPTYGVEVTVQASDRTLLQPWREKLAFILVLQVFGTLGLGFGITSLYYQMHHRRVSLLDLERANASLE
SKVAERTRQLAEGEERMRGFIMAARDAVVIIDQKGIISEFNPSATELFGYDVEEVRGQSVNMLMPATYARDHDGHLRKGK
PSGQRAIGRGREMIGRRKNGSEFPIELTVGTQSFDGTRVHIGVIRDITERKATEETLRRLANIDGLTGVLNRRSFTEESE
LLLSLANRHGRRLSMMIVDADHFKGVNDTYGHDAGDRVLKALTGEIAGVLRKTDLLGRIGGEEFAILLPETDQEGAEGLA
WRVVLAIRALEVPLPEGGVLKVTVSVGVSCRNTEAATFDWMLKEADTALYAAKHGGRDRVACFGQTQSVARS
>Mature_632_residues
MKRVPWVVGGLILIMAYNAALGTLAYWQRRDIIDESLREAVVVADILVREVEANLDRIDRTLSGLTEVLRAYPSAIDVHD
PFTHRLLLRRHAITPSLAALFLIGGDGRLRNASLTDKVSEIDVSGEDYFAFHLSNVDDEFFIGAVTTNRLDKSWVIPVSR
AVRDSFGRLTGVVAATITTDSIDQMIHSHQLSEGFAVTITQRDAGMIGCLGFTRCWGEGAPHRGDEGLAESGGSGEEVHY
LPNGPGVGAFLRGPTYGVEVTVQASDRTLLQPWREKLAFILVLQVFGTLGLGFGITSLYYQMHHRRVSLLDLERANASLE
SKVAERTRQLAEGEERMRGFIMAARDAVVIIDQKGIISEFNPSATELFGYDVEEVRGQSVNMLMPATYARDHDGHLRKGK
PSGQRAIGRGREMIGRRKNGSEFPIELTVGTQSFDGTRVHIGVIRDITERKATEETLRRLANIDGLTGVLNRRSFTEESE
LLLSLANRHGRRLSMMIVDADHFKGVNDTYGHDAGDRVLKALTGEIAGVLRKTDLLGRIGGEEFAILLPETDQEGAEGLA
WRVVLAIRALEVPLPEGGVLKVTVSVGVSCRNTEAATFDWMLKEADTALYAAKHGGRDRVACFGQTQSVARS

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=318, Percent_Identity=30.5031446540881, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081881, Length=294, Percent_Identity=31.9727891156463, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=39.2638036809816, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787541, Length=333, Percent_Identity=28.8288288288288, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=39.3939393939394, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=36.1581920903955, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=32.7586206896552, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=32.7272727272727, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=185, Percent_Identity=33.5135135135135, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=180, Percent_Identity=29.4444444444444, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=33.5329341317365, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 69414; Mature: 69414

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVPWVVGGLILIMAYNAALGTLAYWQRRDIIDESLREAVVVADILVREVEANLDRIDR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSGLTEVLRAYPSAIDVHDPFTHRLLLRRHAITPSLAALFLIGGDGRLRNASLTDKVSE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHCCHHH
IDVSGEDYFAFHLSNVDDEFFIGAVTTNRLDKSWVIPVSRAVRDSFGRLTGVVAATITTD
EECCCCCEEEEEECCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHEEEEEEHH
SIDQMIHSHQLSEGFAVTITQRDAGMIGCLGFTRCWGEGAPHRGDEGLAESGGSGEEVHY
HHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEE
LPNGPGVGAFLRGPTYGVEVTVQASDRTLLQPWREKLAFILVLQVFGTLGLGFGITSLYY
CCCCCCCCCEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMHHRRVSLLDLERANASLESKVAERTRQLAEGEERMRGFIMAARDAVVIIDQKGIISEF
HHHHCEEHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCC
NPSATELFGYDVEEVRGQSVNMLMPATYARDHDGHLRKGKPSGQRAIGRGREMIGRRKNG
CCCHHHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCC
SEFPIELTVGTQSFDGTRVHIGVIRDITERKATEETLRRLANIDGLTGVLNRRSFTEESE
CCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
LLLSLANRHGRRLSMMIVDADHFKGVNDTYGHDAGDRVLKALTGEIAGVLRKTDLLGRIG
HHHHHHHCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEFAILLPETDQEGAEGLAWRVVLAIRALEVPLPEGGVLKVTVSVGVSCRNTEAATFDW
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEECCCCCCHHHH
MLKEADTALYAAKHGGRDRVACFGQTQSVARS
HHHHHHHHHEEHHCCCCCCEEEECCCHHHHCC
>Mature Secondary Structure
MKRVPWVVGGLILIMAYNAALGTLAYWQRRDIIDESLREAVVVADILVREVEANLDRIDR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSGLTEVLRAYPSAIDVHDPFTHRLLLRRHAITPSLAALFLIGGDGRLRNASLTDKVSE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHCCHHH
IDVSGEDYFAFHLSNVDDEFFIGAVTTNRLDKSWVIPVSRAVRDSFGRLTGVVAATITTD
EECCCCCEEEEEECCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHEEEEEEHH
SIDQMIHSHQLSEGFAVTITQRDAGMIGCLGFTRCWGEGAPHRGDEGLAESGGSGEEVHY
HHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEE
LPNGPGVGAFLRGPTYGVEVTVQASDRTLLQPWREKLAFILVLQVFGTLGLGFGITSLYY
CCCCCCCCCEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMHHRRVSLLDLERANASLESKVAERTRQLAEGEERMRGFIMAARDAVVIIDQKGIISEF
HHHHCEEHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCC
NPSATELFGYDVEEVRGQSVNMLMPATYARDHDGHLRKGKPSGQRAIGRGREMIGRRKNG
CCCHHHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCC
SEFPIELTVGTQSFDGTRVHIGVIRDITERKATEETLRRLANIDGLTGVLNRRSFTEESE
CCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
LLLSLANRHGRRLSMMIVDADHFKGVNDTYGHDAGDRVLKALTGEIAGVLRKTDLLGRIG
HHHHHHHCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEFAILLPETDQEGAEGLAWRVVLAIRALEVPLPEGGVLKVTVSVGVSCRNTEAATFDW
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEECCCCCCHHHH
MLKEADTALYAAKHGGRDRVACFGQTQSVARS
HHHHHHHHHEEHHCCCCCCEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]