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The map label for this gene is rppH

Identifier: 83592566

GI number: 83592566

Start: 1452170

End: 1452667

Strand: Reverse

Name: rppH

Synonym: Rru_A1230

Alternate gene names: 83592566

Gene position: 1452667-1452170 (Counterclockwise)

Preceding gene: 83592567

Following gene: 83592565

Centisome position: 33.37

GC content: 68.47

Gene sequence:

>498_bases
ATGACCCCACAACCGCCCCTGTCCGCCGCTGGCCTGCCCTATCGCCAGGGGGTGGGGATCATGCTGATCAACGCCCGGGG
TCAGGTTTTCGTCGCCCGCCGCCTTGACAGTCCCGAGGCTTGGCAGATGCCCCAAGGCGGAATCGACGCCGGCGAGGACC
CCGAGACCGCCGCTTGGCGCGAGATGGAAGAGGAAATCGGCACCCGCAACGCCCTGCTGCTCGGCGAAACCGCCGGCTGG
CTGGGCTATGACCTGCCCGAAGAGCTGCGCGGCCGCCTGTGGGGGGGACGCTTCCAGGGGCAGCGGCAGAAGTGGTTCGC
CTTCCGCTTCACCGGTCAGGACGCCGACATCAACCTCGCCACCGCCCATCCCGAATTCGACGCCTGGCGCTGGGTCGATG
TCGACACCCTGGTGGCGTTGATCGTGCCGTTCAAACGCCCGGTCTATGAGCAGGTGGTGGCCGAACTCGCCGGCTTCGCC
GTTCCCCAGCCGGCCTGA

Upstream 100 bases:

>100_bases
TCTACCGCCTCAATCGCTGGCTGGGGGGACTGGAGGGCGAGGGTCTGGTGCTGGCGCCAGCTTCGGCGGTGATGGTGACC
GGCGAACGGAGAGCCACCCA

Downstream 100 bases:

>100_bases
CCAAGGCCCCTTCCGCGCCCGAAAACGTCATAGGATCATCAAAAACCCCGACCCTCGGCTTTGCTACCCTGCGCGGTCTT
TTTCCACCACAGGGGGTATC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTPQPPLSAAGLPYRQGVGIMLINARGQVFVARRLDSPEAWQMPQGGIDAGEDPETAAWREMEEEIGTRNALLLGETAGW
LGYDLPEELRGRLWGGRFQGQRQKWFAFRFTGQDADINLATAHPEFDAWRWVDVDTLVALIVPFKRPVYEQVVAELAGFA
VPQPA

Sequences:

>Translated_165_residues
MTPQPPLSAAGLPYRQGVGIMLINARGQVFVARRLDSPEAWQMPQGGIDAGEDPETAAWREMEEEIGTRNALLLGETAGW
LGYDLPEELRGRLWGGRFQGQRQKWFAFRFTGQDADINLATAHPEFDAWRWVDVDTLVALIVPFKRPVYEQVVAELAGFA
VPQPA
>Mature_164_residues
TPQPPLSAAGLPYRQGVGIMLINARGQVFVARRLDSPEAWQMPQGGIDAGEDPETAAWREMEEEIGTRNALLLGETAGWL
GYDLPEELRGRLWGGRFQGQRQKWFAFRFTGQDADINLATAHPEFDAWRWVDVDTLVALIVPFKRPVYEQVVAELAGFAV
PQPA

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=153, Percent_Identity=43.1372549019608, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_RHORT (Q2RV14)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426318.1
- ProteinModelPortal:   Q2RV14
- SMR:   Q2RV14
- STRING:   Q2RV14
- GeneID:   3833728
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1230
- NMPDR:   fig|1085.1.peg.3136
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- PhylomeDB:   Q2RV14
- BioCyc:   RRUB269796:RRU_A1230-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18406; Mature: 18275

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQPPLSAAGLPYRQGVGIMLINARGQVFVARRLDSPEAWQMPQGGIDAGEDPETAAWR
CCCCCCCCCCCCCHHCCCCEEEECCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCHHHHH
EMEEEIGTRNALLLGETAGWLGYDLPEELRGRLWGGRFQGQRQKWFAFRFTGQDADINLA
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEE
TAHPEFDAWRWVDVDTLVALIVPFKRPVYEQVVAELAGFAVPQPA
ECCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPQPPLSAAGLPYRQGVGIMLINARGQVFVARRLDSPEAWQMPQGGIDAGEDPETAAWR
CCCCCCCCCCCCHHCCCCEEEECCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCHHHHH
EMEEEIGTRNALLLGETAGWLGYDLPEELRGRLWGGRFQGQRQKWFAFRFTGQDADINLA
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEE
TAHPEFDAWRWVDVDTLVALIVPFKRPVYEQVVAELAGFAVPQPA
ECCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA