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The map label for this gene is atpA

Identifier: 83592560

GI number: 83592560

Start: 1445201

End: 1446733

Strand: Direct

Name: atpA

Synonym: Rru_A1224

Alternate gene names: 83592560

Gene position: 1445201-1446733 (Clockwise)

Preceding gene: 83592559

Following gene: 83592561

Centisome position: 33.2

GC content: 63.14

Gene sequence:

>1533_bases
ATGGAAATCCGCGCTGCGGAGATCTCCGCGATCCTCAAGGAGCAGATCGCGAATTTCGGAACCGAGGCCGAATCCGCCGA
GGTGGGTCAGGTCCTGTCGGTCGGCGACGGCATTGCCCGCGTTTACGGGCTGGACAACGTCCAGGCCGGTGAAATGGTCG
AGTTCGCCAACGGCGTCAAGGGCATGGCCCTTAACCTCGAAAGCGACAACGTCGGTATCGTGATCTTCGGCGAAGATCGC
GGCATCAAGGAAGGCGATGTCGTCAAGCGCACTCAGACGATCGTCGACGTGCCGGTGGGCAAGGGCCTGCTTGGCCGCGT
GGTCGATGGCCTGGGCAATCCGATCGACGGCAAGGGCGATTTGGTCGACGTCGAGCGCAAGCGCGCCGAGGTCAAGGCGC
CGGGCATCATCCCGCGCAAGTCGGTGCACGAGCCGGTGCAGACCGGTATCAAGGCCATCGACAGCCTGATCCCGATCGGC
CGTGGCCAGCGCGAGCTGATCATCGGTGACCGTCAGACCGGCAAGACCGCCGTCATCCTCGACACGATCCTCAATCAGAA
GGCCGTCAACGACAAGGCGAAGGACGATAGCGAGAAGCTGTTCTGCGTCTATGTCGCCGTCGGTCAGAAGCGCTCGACCG
TGGCCCAGGTCGTCAAGGTCCTGGCCGATCACGGCGCGCTGGATTACACCATCGTCGTCGCCGCCACCGCGTCCGAACCC
GCTCCCTTGCAGTTCCTGGCTCCCTATACCGGCTGCACGATGGGCGAGTTCTTCCGCGACAACGGCATGCACGCGGTGAT
CTTCTATGACGATCTGACCAAGCAGGCCGTGGCCTACCGTCAGATGTCGCTGCTGCTGCGCCGCCCGCCCGGGCGCGAAG
CCTTCCCCGGCGACGTGTTCTATCTCCACTCCCGTTTGCTCGAACGCGCCGCCAAGCTCAATGACGACAACGGCGCCGGC
TCCCTGACCGCCCTGCCGGTCATCGAGACCCAGGCGAACGACGTGTCGGCCTATATTCCGACCAACGTGATTTCGATCAC
CGACGGCCAGATCTTTCTGGAAACCGACCTGTTCTTCAAGGGCATCCGCCCGGCGGTGAACGTCGGCCTGTCGGTGTCGC
GCGTTGGCTCATCGGCCCAGATCAAGGCGATGAAGCAGGTTGCCGGCTCGATCAAGCTGGAACTCGCCCAGTACCGTGAA
ATGGCCGCCTTCGCCCAGTTCGCCTCCGACCTCGATCCCGCCACCCAGAAGCTTCTGGCCCGCGGCGCGCGGTTGACCGA
ATTGCTCAAGCAGGCCCAGTACTCGCCGCTCGCCGTCGAGGAACAGGTTTGCGTGATCTATGCCGGTACGCGCGGCTATC
TGGACAAGCTCAAGACCACCGATGTGGTGCGTTACGAGGCTTCGCTGCTCGGCGCTTTGCGCACCTCGGGCGCCGATCTT
CTCGAATCGATCCGCACCGGCAAGGCTCTGTCCAAGGAAATCGAGCAGAAGCTGGTCAAGTTCCTGGACGATTTCGGCAA
GAAGTTTGCCTGA

Upstream 100 bases:

>100_bases
TTCTGGGCGGGATGGTCGTGCGCGTTGGATCGCGTATGGTCGACAGTTCCCTCAGCACAAAGCTCAAACGGTTGCAACTC
GCCATGAAAGGGGTTGGGTG

Downstream 100 bases:

>100_bases
TTTCGCTCACGGATTGACTCCAGAGGGACCAGGGAAGGGCTCCGAGAACCATGGCCAGCCTTAAAGACCTCAGAAGCCGG
ATCACCTCGGTCAAATCGAC

Product: ATP synthase F1, subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVKGMALNLESDNVGIVIFGEDR
GIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGDLVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAVILDTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEP
APLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLNDDNGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYRE
MAAFAQFASDLDPATQKLLARGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADL
LESIRTGKALSKEIEQKLVKFLDDFGKKFA

Sequences:

>Translated_510_residues
MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVKGMALNLESDNVGIVIFGEDR
GIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGDLVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAVILDTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEP
APLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLNDDNGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYRE
MAAFAQFASDLDPATQKLLARGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADL
LESIRTGKALSKEIEQKLVKFLDDFGKKFA
>Mature_510_residues
MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVKGMALNLESDNVGIVIFGEDR
GIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGDLVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAVILDTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEP
APLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLNDDNGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYRE
MAAFAQFASDLDPATQKLLARGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADL
LESIRTGKALSKEIEQKLVKFLDDFGKKFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=500, Percent_Identity=70.4, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=500, Percent_Identity=70.4, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=296, Percent_Identity=29.7297297297297, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913426, Length=296, Percent_Identity=29.0540540540541, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI32189394, Length=409, Percent_Identity=23.4718826405868, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI19913424, Length=331, Percent_Identity=23.5649546827795, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=56.5891472868217, Blast_Score=568, Evalue=1e-163,
Organism=Escherichia coli, GI1790170, Length=432, Percent_Identity=25.2314814814815, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788251, Length=351, Percent_Identity=26.7806267806268, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=71.031746031746, Blast_Score=733, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=71.031746031746, Blast_Score=731, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=65.8730158730159, Blast_Score=665, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=293, Percent_Identity=28.3276450511945, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=324, Percent_Identity=26.5432098765432, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=59.2105263157895, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=302, Percent_Identity=25.4966887417219, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=68, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=68.986083499006, Blast_Score=711, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=328, Percent_Identity=28.6585365853659, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=419, Percent_Identity=25.5369928400955, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=69.5652173913043, Blast_Score=721, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=336, Percent_Identity=27.0833333333333, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24646341, Length=336, Percent_Identity=27.0833333333333, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17136796, Length=336, Percent_Identity=27.0833333333333, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24638766, Length=410, Percent_Identity=25.1219512195122, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574560, Length=410, Percent_Identity=25.3658536585366, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583992, Length=344, Percent_Identity=23.8372093023256, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583988, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583986, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583984, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_RHORT (Q2RV20)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426312.1
- ProteinModelPortal:   Q2RV20
- SMR:   Q2RV20
- STRING:   Q2RV20
- GeneID:   3833722
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1224
- NMPDR:   fig|1085.1.peg.3142
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q2RV20
- BioCyc:   RRUB269796:RRU_A1224-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55027; Mature: 55027

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVK
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHCCCC
GMALNLESDNVGIVIFGEDRGIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGD
CEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHHCCCCCCCCCC
LVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAVIL
EEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEP
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
APLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVF
CCEEEECCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDDNGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFK
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLA
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADL
CCHHHHHHHHHCCCCCCEECCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCCCHHH
LESIRTGKALSKEIEQKLVKFLDDFGKKFA
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVK
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHCCCC
GMALNLESDNVGIVIFGEDRGIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGD
CEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHHCCCCCCCCCC
LVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAVIL
EEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEP
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
APLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVF
CCEEEECCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDDNGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFK
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLA
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADL
CCHHHHHHHHHCCCCCCEECCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCCCHHH
LESIRTGKALSKEIEQKLVKFLDDFGKKFA
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA