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The map label for this gene is fusA [C]

Identifier: 83592476

GI number: 83592476

Start: 1344652

End: 1346667

Strand: Direct

Name: fusA [C]

Synonym: Rru_A1140

Alternate gene names: 83592476

Gene position: 1344652-1346667 (Clockwise)

Preceding gene: 83592475

Following gene: 83592480

Centisome position: 30.89

GC content: 65.38

Gene sequence:

>2016_bases
ATGCCCGACAGAGCGTCCGCGCCGCGTGTGGCGGCGATCGTTGGGCCTTACGCCAGTGGCAAGACCAGTCTTTTGGAAAG
CCTGCTGCTGGCGACCGAGGCCATCCACCGCAAGGGAACGATCCAAGACCACAATACCGTCGGCGATTCCTCTCCCGAAG
CCCGCGACCGAGAAATGGGCGTCGAGGTCAATCTGGCCGAAACCACCTATCTTGGCGGACAATGGACCTTTCTCGACTGT
CCGGGATCGGTCGAGTTCATGCAAGACACCTATAACGCGCTGACCGTCTGCGATGTCGCCGTCGTCGTCTGCGAACCCGA
TCCCGCCCGCGCCGTGATGCTGACGCCGCTGTTGAAATTCCTCGATAGCCGCGCCATCCCCCATATGATCTTCATCAACA
AGATCGAAACCACCGAAACCCACCTGCGCGACATGATCGAGGCCCTGCAGATGGTCTCGACCAAGCCGCTGGTCGCCCGC
GAGATTCCCATCCGCGAAGACGGCAAGGTGGTTGGCTATCTCGATCTGGTCAGCGAGCGCGCCTATCGCTACAAGCCGGG
CGAGGCCAGCGATCTGATCTCGATCCCCGAGGATCTGAAAGACCGCCACGTCAACGAACGCCAGGAGCTTTTGGAAAATC
TGGCCGATTACGACGACGCCCTGCTCGAGGGGCTGTTGTCGGACGTGGTGCCGCCCAAGGGCGCGGTCTATGACTCCCTG
GCCCGCGATCTGGCCGAGGATCTGGTGGTGCCGGTGTTCTTTGGCGGCGCCCTGGCCGATAACGGCATCCGCCGCCTGCT
CAAGGCGCTCCGCCACGAAAGCCCGACGCTGGAGGAGACCCGCGCCCGCCTGGGCATCGAAGGCAAGGGGCCGGTCATCC
AGGTCTTCAAGACCCAGCACGCCGAGCATATGGGCAAGCTGTCGTTGGCCCGGCTATGGAACGGCACCTTGAAGGATGGT
CAGGCGCTGAACGGCGATCGCGCCACCGGGCTTTTCAGCTTCCCGGCCGGCCAGCAAGCCAAGGTCGATAGTGTCGGCGC
CGGGGCGGTCGTGGGCATCGGCAAGCTGGAAAAGCTGTCGACCGGCGCCCTGGTTGGCGGCGACAGCGCCGCCGACGACC
CGCCGGTCCTGGGACCGCTGTTCGCCCTTGCCCTGCATGCCCGCAAACAGGGCGACGATGTCAAGCTGACCGGCGCCCTG
GCCAAGCTGTGCGAGGAGGATCCCTCGCTGCGCGTCGAAAACAATCCCGACACCGCCGAGCTGCTGCTGTGGGGGCAGGG
CGATATCCATCTGCAGATCGCCGTGCGCCGGCTGGCCCGCCAGTTCCACGTCGAGGTCGAGGCCCATCGTCCGCAGGTGC
CCTATAAGGAGACCATCCGCAAGGCGACCAGCCGCCAGGGCCGCTTCAAGCGCCAGACCGGCGGCCACGGCCAATTCGGC
GATGTGCATCTCGATATCAAGCCGCTGTCGCGCGGCGAAGGCTTCGTCTTCACCGACAGCATCACCGGCGGCGTGGTCCC
CCGGCAGTATATTCCGGCGGTCGAACAGGGGATCCGCGAGTTCCTGCCGCGCGGCCCCTTGGGCTTCCCGGTGGTCGATG
TCGGCGTCACCTTGACCGATGGCAGCTATCACGTGGTCGACAGCTCGGAACAGGCCTTCAAATCGGCCGCCCAGCTGGCG
ATGCGCGAGGGCATGCCGGCCTGCGAGCCGGTGCTGCTTGAACCGATCCTGCGCGTCGAGATCAGCGTGCCGACCGACGC
CACCAGCCGGGCCCAGCGCGCCCTGACCACACGGCGCGGCCAGATCCTCGGCTATACGCCCAAAGAGGGGTGGAGCGGCT
GGGACGTGGTCGAGGGCTATCTGCCCCAATCCGAAATGCACGATCTGATCACCGATCTGCGCTCGGCGACCATGGGCGTG
GGCACCTTCGCCTGGAGCTTCGACCACCTGCAAGAGGTCATCGGCAAACAGGCCGACGAGGTGGTCACCGCCCGCAAACT
GGTTTTGGCCGGCTAA

Upstream 100 bases:

>100_bases
GCGTCGCGACCCGGCTCTGGGGTATCGGGGGGCGTTGCCGCAGGTCGCCGGGTTCGGTCCGCGCCCCCATCAATGAAGAA
TGATCAGGGGAGTGAAGCCC

Downstream 100 bases:

>100_bases
CGGCGCGCGCCCTCATCCAAAGCGGGAGGCCCCCAAAGCGGGCCTCCCAGTCCGTGATCGGAAGATCGCATGGAGCGATC
GGACGATTAGACTTTATGTT

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPDRASAPRVAAIVGPYASGKTSLLESLLLATEAIHRKGTIQDHNTVGDSSPEARDREMGVEVNLAETTYLGGQWTFLDC
PGSVEFMQDTYNALTVCDVAVVVCEPDPARAVMLTPLLKFLDSRAIPHMIFINKIETTETHLRDMIEALQMVSTKPLVAR
EIPIREDGKVVGYLDLVSERAYRYKPGEASDLISIPEDLKDRHVNERQELLENLADYDDALLEGLLSDVVPPKGAVYDSL
ARDLAEDLVVPVFFGGALADNGIRRLLKALRHESPTLEETRARLGIEGKGPVIQVFKTQHAEHMGKLSLARLWNGTLKDG
QALNGDRATGLFSFPAGQQAKVDSVGAGAVVGIGKLEKLSTGALVGGDSAADDPPVLGPLFALALHARKQGDDVKLTGAL
AKLCEEDPSLRVENNPDTAELLLWGQGDIHLQIAVRRLARQFHVEVEAHRPQVPYKETIRKATSRQGRFKRQTGGHGQFG
DVHLDIKPLSRGEGFVFTDSITGGVVPRQYIPAVEQGIREFLPRGPLGFPVVDVGVTLTDGSYHVVDSSEQAFKSAAQLA
MREGMPACEPVLLEPILRVEISVPTDATSRAQRALTTRRGQILGYTPKEGWSGWDVVEGYLPQSEMHDLITDLRSATMGV
GTFAWSFDHLQEVIGKQADEVVTARKLVLAG

Sequences:

>Translated_671_residues
MPDRASAPRVAAIVGPYASGKTSLLESLLLATEAIHRKGTIQDHNTVGDSSPEARDREMGVEVNLAETTYLGGQWTFLDC
PGSVEFMQDTYNALTVCDVAVVVCEPDPARAVMLTPLLKFLDSRAIPHMIFINKIETTETHLRDMIEALQMVSTKPLVAR
EIPIREDGKVVGYLDLVSERAYRYKPGEASDLISIPEDLKDRHVNERQELLENLADYDDALLEGLLSDVVPPKGAVYDSL
ARDLAEDLVVPVFFGGALADNGIRRLLKALRHESPTLEETRARLGIEGKGPVIQVFKTQHAEHMGKLSLARLWNGTLKDG
QALNGDRATGLFSFPAGQQAKVDSVGAGAVVGIGKLEKLSTGALVGGDSAADDPPVLGPLFALALHARKQGDDVKLTGAL
AKLCEEDPSLRVENNPDTAELLLWGQGDIHLQIAVRRLARQFHVEVEAHRPQVPYKETIRKATSRQGRFKRQTGGHGQFG
DVHLDIKPLSRGEGFVFTDSITGGVVPRQYIPAVEQGIREFLPRGPLGFPVVDVGVTLTDGSYHVVDSSEQAFKSAAQLA
MREGMPACEPVLLEPILRVEISVPTDATSRAQRALTTRRGQILGYTPKEGWSGWDVVEGYLPQSEMHDLITDLRSATMGV
GTFAWSFDHLQEVIGKQADEVVTARKLVLAG
>Mature_670_residues
PDRASAPRVAAIVGPYASGKTSLLESLLLATEAIHRKGTIQDHNTVGDSSPEARDREMGVEVNLAETTYLGGQWTFLDCP
GSVEFMQDTYNALTVCDVAVVVCEPDPARAVMLTPLLKFLDSRAIPHMIFINKIETTETHLRDMIEALQMVSTKPLVARE
IPIREDGKVVGYLDLVSERAYRYKPGEASDLISIPEDLKDRHVNERQELLENLADYDDALLEGLLSDVVPPKGAVYDSLA
RDLAEDLVVPVFFGGALADNGIRRLLKALRHESPTLEETRARLGIEGKGPVIQVFKTQHAEHMGKLSLARLWNGTLKDGQ
ALNGDRATGLFSFPAGQQAKVDSVGAGAVVGIGKLEKLSTGALVGGDSAADDPPVLGPLFALALHARKQGDDVKLTGALA
KLCEEDPSLRVENNPDTAELLLWGQGDIHLQIAVRRLARQFHVEVEAHRPQVPYKETIRKATSRQGRFKRQTGGHGQFGD
VHLDIKPLSRGEGFVFTDSITGGVVPRQYIPAVEQGIREFLPRGPLGFPVVDVGVTLTDGSYHVVDSSEQAFKSAAQLAM
REGMPACEPVLLEPILRVEISVPTDATSRAQRALTTRRGQILGYTPKEGWSGWDVVEGYLPQSEMHDLITDLRSATMGVG
TFAWSFDHLQEVIGKQADEVVTARKLVLAG

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=688, Percent_Identity=25.4360465116279, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI19923640, Length=669, Percent_Identity=25.2615844544096, Blast_Score=169, Evalue=9e-42,
Organism=Homo sapiens, GI25306287, Length=639, Percent_Identity=25.1956181533646, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI25306283, Length=333, Percent_Identity=26.7267267267267, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789738, Length=692, Percent_Identity=29.4797687861272, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI1790835, Length=494, Percent_Identity=22.2672064777328, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17533571, Length=665, Percent_Identity=27.0676691729323, Blast_Score=230, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17556745, Length=714, Percent_Identity=21.0084033613445, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323098, Length=683, Percent_Identity=28.2576866764275, Blast_Score=248, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6322359, Length=694, Percent_Identity=21.9020172910663, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24582462, Length=684, Percent_Identity=27.046783625731, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI221458488, Length=699, Percent_Identity=23.4620886981402, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 73045; Mature: 72914

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRASAPRVAAIVGPYASGKTSLLESLLLATEAIHRKGTIQDHNTVGDSSPEARDREMG
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCC
VEVNLAETTYLGGQWTFLDCPGSVEFMQDTYNALTVCDVAVVVCEPDPARAVMLTPLLKF
EEEEEEHEEEECCEEEEEECCCCHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHH
LDSRAIPHMIFINKIETTETHLRDMIEALQMVSTKPLVAREIPIREDGKVVGYLDLVSER
HHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEHHHHHHHH
AYRYKPGEASDLISIPEDLKDRHVNERQELLENLADYDDALLEGLLSDVVPPKGAVYDSL
HHCCCCCCCCHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARDLAEDLVVPVFFGGALADNGIRRLLKALRHESPTLEETRARLGIEGKGPVIQVFKTQH
HHHHHHHCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEHHHH
AEHMGKLSLARLWNGTLKDGQALNGDRATGLFSFPAGQQAKVDSVGAGAVVGIGKLEKLS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCHHHHC
TGALVGGDSAADDPPVLGPLFALALHARKQGDDVKLTGALAKLCEEDPSLRVENNPDTAE
CCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCEEECCCCCCEE
LLLWGQGDIHLQIAVRRLARQFHVEVEAHRPQVPYKETIRKATSRQGRFKRQTGGHGQFG
EEEECCCCEEHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
DVHLDIKPLSRGEGFVFTDSITGGVVPRQYIPAVEQGIREFLPRGPLGFPVVDVGVTLTD
EEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
GSYHVVDSSEQAFKSAAQLAMREGMPACEPVLLEPILRVEISVPTDATSRAQRALTTRRG
CCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHCHHHEEEEECCCCHHHHHHHHHHHHCC
QILGYTPKEGWSGWDVVEGYLPQSEMHDLITDLRSATMGVGTFAWSFDHLQEVIGKQADE
CEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
VVTARKLVLAG
HHHHHHHHCCC
>Mature Secondary Structure 
PDRASAPRVAAIVGPYASGKTSLLESLLLATEAIHRKGTIQDHNTVGDSSPEARDREMG
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCC
VEVNLAETTYLGGQWTFLDCPGSVEFMQDTYNALTVCDVAVVVCEPDPARAVMLTPLLKF
EEEEEEHEEEECCEEEEEECCCCHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHH
LDSRAIPHMIFINKIETTETHLRDMIEALQMVSTKPLVAREIPIREDGKVVGYLDLVSER
HHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEHHHHHHHH
AYRYKPGEASDLISIPEDLKDRHVNERQELLENLADYDDALLEGLLSDVVPPKGAVYDSL
HHCCCCCCCCHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARDLAEDLVVPVFFGGALADNGIRRLLKALRHESPTLEETRARLGIEGKGPVIQVFKTQH
HHHHHHHCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEHHHH
AEHMGKLSLARLWNGTLKDGQALNGDRATGLFSFPAGQQAKVDSVGAGAVVGIGKLEKLS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCHHHHC
TGALVGGDSAADDPPVLGPLFALALHARKQGDDVKLTGALAKLCEEDPSLRVENNPDTAE
CCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCEEECCCCCCEE
LLLWGQGDIHLQIAVRRLARQFHVEVEAHRPQVPYKETIRKATSRQGRFKRQTGGHGQFG
EEEECCCCEEHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
DVHLDIKPLSRGEGFVFTDSITGGVVPRQYIPAVEQGIREFLPRGPLGFPVVDVGVTLTD
EEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
GSYHVVDSSEQAFKSAAQLAMREGMPACEPVLLEPILRVEISVPTDATSRAQRALTTRRG
CCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHCHHHEEEEECCCCHHHHHHHHHHHHCC
QILGYTPKEGWSGWDVVEGYLPQSEMHDLITDLRSATMGVGTFAWSFDHLQEVIGKQADE
CEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
VVTARKLVLAG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]