Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 83592471

GI number: 83592471

Start: 1339162

End: 1340364

Strand: Direct

Name: aatA [H]

Synonym: Rru_A1135

Alternate gene names: 83592471

Gene position: 1339162-1340364 (Clockwise)

Preceding gene: 83592470

Following gene: 83592472

Centisome position: 30.77

GC content: 64.67

Gene sequence:

>1203_bases
ATGTCGATCGTCGCCGAGCGTCTGTCCGCCATCAAACCGTCGCCGACCCTGGCGGTTACCACCAAGGCCGCCGAACTCAA
GGCCGCCGGCCGTGACATTATCGGTCTGGGCGCGGGCGAACCCGACTTCGATACCCCCGATCACATCAAACAGGCGGCGA
TCGCCGCCATCGAGCGCGGCGAGACCAAATACACCGCCGTTCCCGGCACCGCCGCCCTGCGCAAGGCGATCTGCGCCAAG
CTCAAGCGCGAGAACGATCTTGAGTACACGATCGAAGAGATCAGCGTCGGCTGCGGTGGCAAGCAGACCATCTACAACGC
CCTGATGGCGACGCTGAACCCGGGCGAGGAGGTGATCATCCCCGCGCCTTATTGGGTCAGCTATCCCGATATCGCCCTGT
TGGCCGGCGGCGTGCCGGTGTTCGTTCCCAGCGGCCCCGAGGTCGGCTTCAAGCTGCAGCCCGCCGATCTGGAGCGCGCC
ATCACGCCCAAGACCAAATGGCTGATCCTCAACAGCCCGTCCAATCCGACGGGCGTGGCCTATTCGGCCGCCGATCTCAA
GGCCCTGGCCGAGGTTCTGCTCAAGCATCCCCATGTCTGGGTGATGACCGACGATATGTACGAGCACCTCGTCTATGACG
GCTTCAAGTTCGCCACCATCGCCCAGGTCGAGCCCAAGCTGAAGGACCGCACCCTGACGCTGAACGGCGTTTCCAAGTCG
TTCGCCATGACCGGCTGGCGCGTCGGCTATGCCGCCGGCCCGGTGGCGGTGATCAAGGCGATCAACAAGATCCAAAGCCA
GTCGACCACCCACACCAGCTCGATCAGTCAGGCCGCCGCCCTTGCCGCCCTTGAAGGGCCGATGGACTTCCTGATCGAAC
GCAACGCCATCTTCAAGGAACGCCGCGATCTGGTCGTGCGCATGATCAATGATTGCCCGGGCCTGTCGGTCGGCACGCCG
GAAGGCGCCTTCTATGTCTATCCGTCCTGCGCCGGGGTGATCGGCAAGACGACGCCCGAGGGCAAGCTGCTGGAAACCGA
CAGCGATTTCGTCGCCGCCCTGCTCGAAAGCGAAGGGGTCGCCGCCGTTCAGGGCGTGGCCTTCGGCCTGTCGCCCTATT
TCCGCATCAGCTACGCCACGGCGACCGCCACCCTGGAGGACGCCTGCCAGCGCATCCGCCGCTTCTGCGAAAGCCTGCGT
TGA

Upstream 100 bases:

>100_bases
TAGCTTTTTCCCCCGGTCCCGCCAAGAGAGCCCCCGTCGTCAGGGGCGGCGCGGCCACTCGCCCCCTCCCAACCGACACA
ACCAATCCTCGAGGATTTCC

Downstream 100 bases:

>100_bases
CTTCTCTCCACCGCGCAAGCCGGATCTGATGGAAAGGGCGCCCTTCGCGGGGCGCCCTTTTTTTCGTCTGGGGGCTTGGC
GCGGTCATATAGGAACCTTG

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSIVAERLSAIKPSPTLAVTTKAAELKAAGRDIIGLGAGEPDFDTPDHIKQAAIAAIERGETKYTAVPGTAALRKAICAK
LKRENDLEYTIEEISVGCGGKQTIYNALMATLNPGEEVIIPAPYWVSYPDIALLAGGVPVFVPSGPEVGFKLQPADLERA
ITPKTKWLILNSPSNPTGVAYSAADLKALAEVLLKHPHVWVMTDDMYEHLVYDGFKFATIAQVEPKLKDRTLTLNGVSKS
FAMTGWRVGYAAGPVAVIKAINKIQSQSTTHTSSISQAAALAALEGPMDFLIERNAIFKERRDLVVRMINDCPGLSVGTP
EGAFYVYPSCAGVIGKTTPEGKLLETDSDFVAALLESEGVAAVQGVAFGLSPYFRISYATATATLEDACQRIRRFCESLR

Sequences:

>Translated_400_residues
MSIVAERLSAIKPSPTLAVTTKAAELKAAGRDIIGLGAGEPDFDTPDHIKQAAIAAIERGETKYTAVPGTAALRKAICAK
LKRENDLEYTIEEISVGCGGKQTIYNALMATLNPGEEVIIPAPYWVSYPDIALLAGGVPVFVPSGPEVGFKLQPADLERA
ITPKTKWLILNSPSNPTGVAYSAADLKALAEVLLKHPHVWVMTDDMYEHLVYDGFKFATIAQVEPKLKDRTLTLNGVSKS
FAMTGWRVGYAAGPVAVIKAINKIQSQSTTHTSSISQAAALAALEGPMDFLIERNAIFKERRDLVVRMINDCPGLSVGTP
EGAFYVYPSCAGVIGKTTPEGKLLETDSDFVAALLESEGVAAVQGVAFGLSPYFRISYATATATLEDACQRIRRFCESLR
>Mature_399_residues
SIVAERLSAIKPSPTLAVTTKAAELKAAGRDIIGLGAGEPDFDTPDHIKQAAIAAIERGETKYTAVPGTAALRKAICAKL
KRENDLEYTIEEISVGCGGKQTIYNALMATLNPGEEVIIPAPYWVSYPDIALLAGGVPVFVPSGPEVGFKLQPADLERAI
TPKTKWLILNSPSNPTGVAYSAADLKALAEVLLKHPHVWVMTDDMYEHLVYDGFKFATIAQVEPKLKDRTLTLNGVSKSF
AMTGWRVGYAAGPVAVIKAINKIQSQSTTHTSSISQAAALAALEGPMDFLIERNAIFKERRDLVVRMINDCPGLSVGTPE
GAFYVYPSCAGVIGKTTPEGKLLETDSDFVAALLESEGVAAVQGVAFGLSPYFRISYATATATLEDACQRIRRFCESLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=428, Percent_Identity=28.5046728971963, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI169881279, Length=428, Percent_Identity=28.5046728971963, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI56713256, Length=396, Percent_Identity=28.2828282828283, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=28.2828282828283, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881281, Length=421, Percent_Identity=26.603325415677, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4507369, Length=398, Percent_Identity=24.8743718592965, Blast_Score=102, Evalue=9e-22,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=27.0053475935829, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788722, Length=357, Percent_Identity=33.0532212885154, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=27.4358974358974, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790797, Length=270, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=292, Percent_Identity=30.8219178082192, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=292, Percent_Identity=30.8219178082192, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=25.5874673629243, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=259, Percent_Identity=25.8687258687259, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=23.7837837837838, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=400, Percent_Identity=28.75, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=348, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573069, Length=395, Percent_Identity=26.3291139240506, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646114, Length=395, Percent_Identity=26.3291139240506, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573067, Length=395, Percent_Identity=26.3291139240506, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573065, Length=395, Percent_Identity=26.3291139240506, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=24.21875, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42864; Mature: 42732

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVAERLSAIKPSPTLAVTTKAAELKAAGRDIIGLGAGEPDFDTPDHIKQAAIAAIERG
CCHHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
ETKYTAVPGTAALRKAICAKLKRENDLEYTIEEISVGCGGKQTIYNALMATLNPGEEVII
CCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCHHHHHHHHHHHCCCCCEEEE
PAPYWVSYPDIALLAGGVPVFVPSGPEVGFKLQPADLERAITPKTKWLILNSPSNPTGVA
CCCCCCCCCCHHEEECCCEEEECCCCCCCEEECCHHHHHCCCCCEEEEEEECCCCCCCEE
YSAADLKALAEVLLKHPHVWVMTDDMYEHLVYDGFKFATIAQVEPKLKDRTLTLNGVSKS
ECHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHH
FAMTGWRVGYAAGPVAVIKAINKIQSQSTTHTSSISQAAALAALEGPMDFLIERNAIFKE
HHHCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
RRDLVVRMINDCPGLSVGTPEGAFYVYPSCAGVIGKTTPEGKLLETDSDFVAALLESEGV
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCC
AAVQGVAFGLSPYFRISYATATATLEDACQRIRRFCESLR
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIVAERLSAIKPSPTLAVTTKAAELKAAGRDIIGLGAGEPDFDTPDHIKQAAIAAIERG
CHHHHHHHHCCCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
ETKYTAVPGTAALRKAICAKLKRENDLEYTIEEISVGCGGKQTIYNALMATLNPGEEVII
CCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCHHHHHHHHHHHCCCCCEEEE
PAPYWVSYPDIALLAGGVPVFVPSGPEVGFKLQPADLERAITPKTKWLILNSPSNPTGVA
CCCCCCCCCCHHEEECCCEEEECCCCCCCEEECCHHHHHCCCCCEEEEEEECCCCCCCEE
YSAADLKALAEVLLKHPHVWVMTDDMYEHLVYDGFKFATIAQVEPKLKDRTLTLNGVSKS
ECHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHH
FAMTGWRVGYAAGPVAVIKAINKIQSQSTTHTSSISQAAALAALEGPMDFLIERNAIFKE
HHHCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
RRDLVVRMINDCPGLSVGTPEGAFYVYPSCAGVIGKTTPEGKLLETDSDFVAALLESEGV
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCC
AAVQGVAFGLSPYFRISYATATATLEDACQRIRRFCESLR
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]