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The map label for this gene is purE [H]

Identifier: 83592386

GI number: 83592386

Start: 1243289

End: 1243792

Strand: Direct

Name: purE [H]

Synonym: Rru_A1050

Alternate gene names: 83592386

Gene position: 1243289-1243792 (Clockwise)

Preceding gene: 83592384

Following gene: 83592387

Centisome position: 28.56

GC content: 68.65

Gene sequence:

>504_bases
ATGCATACCCCCTCGGAGGCGCCGCTGGTCGGCGTCATCATGGGCAGCCAGTCGGACTGGGCTACCCTGCGCCATGCCTG
GGACATCCTGGAGATGCTGGGCGTTCCGGCGGAAAAGCGCATTATTTCCGCCCATCGGACCCCGGCGCGGCTGGTTGATT
ACGCGACGACGGCGCGGGCGCGCGGCCTAAGGGCGATCGTCGCCGGCGCCGGCGGCGCGGCCCATCTACCGGGCATGGTG
GCGGCGATGACCACCTTGCCGGTCTTTGGGGTTCCGGTTGAAAGCAAGGCGCTTTCGGGAATGGACAGCCTGCTGTCGAT
CGTGCAGATGCCGGGCGGCGTGCCGGTGGGAACCCTGGCCATCGGCAAGGCCGGGGCGATCAACGCCGGGCTGATCGCCG
CCTCGGTGGTCGCGCTGTCGCGACCCGATATCGAGGCGAAGCTGATCTCCTGGCGCGACCGCCAGACGGCCGAGGTCGCC
GAAGAACCGGTGGATGAGGGTTAA

Upstream 100 bases:

>100_bases
CGGCGCGCCCCGTCATCATGCCGGCCGGCGCCGCTTGCCAGAGGGGGCCGGGCTCGCCATACTCCGCCGCTTTCCGCAAT
CGGGGCAAAGGGAACCAGCC

Downstream 100 bases:

>100_bases
GTGATGGCCATGGTTGGACGGCTGGCGGCCTTGGGGCCTGTGGGGCCGGGCGCGCGATTGGGAATTCTGGGCGGTGGCCA
GCTTGGCCGGATGACGGCGC

Product: phosphoribosylaminoimidazole carboxylase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MHTPSEAPLVGVIMGSQSDWATLRHAWDILEMLGVPAEKRIISAHRTPARLVDYATTARARGLRAIVAGAGGAAHLPGMV
AAMTTLPVFGVPVESKALSGMDSLLSIVQMPGGVPVGTLAIGKAGAINAGLIAASVVALSRPDIEAKLISWRDRQTAEVA
EEPVDEG

Sequences:

>Translated_167_residues
MHTPSEAPLVGVIMGSQSDWATLRHAWDILEMLGVPAEKRIISAHRTPARLVDYATTARARGLRAIVAGAGGAAHLPGMV
AAMTTLPVFGVPVESKALSGMDSLLSIVQMPGGVPVGTLAIGKAGAINAGLIAASVVALSRPDIEAKLISWRDRQTAEVA
EEPVDEG
>Mature_167_residues
MHTPSEAPLVGVIMGSQSDWATLRHAWDILEMLGVPAEKRIISAHRTPARLVDYATTARARGLRAIVAGAGGAAHLPGMV
AAMTTLPVFGVPVESKALSGMDSLLSIVQMPGGVPVGTLAIGKAGAINAGLIAASVVALSRPDIEAKLISWRDRQTAEVA
EEPVDEG

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=158, Percent_Identity=56.9620253164557, Blast_Score=154, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324702, Length=152, Percent_Identity=52.6315789473684, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17248; Mature: 17248

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPSEAPLVGVIMGSQSDWATLRHAWDILEMLGVPAEKRIISAHRTPARLVDYATTARA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
RGLRAIVAGAGGAAHLPGMVAAMTTLPVFGVPVESKALSGMDSLLSIVQMPGGVPVGTLA
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IGKAGAINAGLIAASVVALSRPDIEAKLISWRDRQTAEVAEEPVDEG
CCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MHTPSEAPLVGVIMGSQSDWATLRHAWDILEMLGVPAEKRIISAHRTPARLVDYATTARA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
RGLRAIVAGAGGAAHLPGMVAAMTTLPVFGVPVESKALSGMDSLLSIVQMPGGVPVGTLA
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IGKAGAINAGLIAASVVALSRPDIEAKLISWRDRQTAEVAEEPVDEG
CCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]