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The map label for this gene is ftsA [H]

Identifier: 83592281

GI number: 83592281

Start: 1127986

End: 1129308

Strand: Reverse

Name: ftsA [H]

Synonym: Rru_A0945

Alternate gene names: 83592281

Gene position: 1129308-1127986 (Counterclockwise)

Preceding gene: 83592282

Following gene: 83592280

Centisome position: 25.94

GC content: 67.95

Gene sequence:

>1323_bases
ATGCCTAGAGACGCCATCAGCAAAGACACCCCCACCGCGGCCCGGACGCGGCGGAAGGATCACAGGGCGGCCCCGCCCCG
ACGCCAGCGCGGCGGGTTGATCACCGCCCTTGACGTGGGAACCACCAAGATCGCCTGCTTCATCGCCCGCGAGGAAGAGG
ACGGCGCGTTGCGCGTGCTCGGCGTCGGCCATCACCGGTCGCGCGGCATGCGCAACGGTCAGGTGGCCAATATGGACGAG
GTCGAGCTGTCGGTTCGCGCCGCCGTCGACGCCGCCGAGCAGATGGCCAACGAGCGCATCTCCAGCGTCGTCGTCAACGT
CAGCGGCGGCCAGCCCCATTCGACCCGGGTCGAGGTCGAGATGTCGATCGCCGGCCACGAGGTGCGCGGCAATGACGTGC
GCCGCATCCAGGCCTATGGCCGGGGCCTGCATACCTCGGCCGACCGCGAGTTGGTCCACTGCATTCCGGTGTCCTACGCC
ATCGACGGCACCGAGGGCGTGCTCGACCCGCGCGGCATGTTCGGCCAGAGCCTGGGGGTGTCGATCCATCTGGTATCGGC
CGCCGCCGGACCGTTGCGCAATCTGTCGACCGTTGTCGAGCGCTGCCACCTCGATATCGAGGACAAGGTGGTCAGCCCCT
ATGCCTCGGGTCTCGCCTGTCTGGTCGAGGACGAGAAGCAGATGGGGGTGACGGTCATCGACCTCGGCGGCGGCACCACC
TCGATCGCCGTTTTCCACGAGGGCCATGTCGTCCACACCGAGATGATCCCGGTGGGCGGACTGCATGTGACCAACGATAT
CGCCAAGGGCTTGACGACCCCGGTCGCCAATGCCGAACGGCTCAAGACCATTCATGGCAGTTGCTCGGTCTCGCCCGCCG
ACACCCGCGAGATCCTGCGGGTGCCGCTGGTCGGCGAGGACGACGAGGCGACCGCCAACGAAGTGCCCCGCTCCATGTTG
GTGCAGATCATCCGCCCGCGCATCGAAGAGACCTTCGAACTGGTGCGCGGCCGCCTGGAAGCCAGCGGCTTCGACAAGGT
CGGCGGACGGCTGGTCGTGCTGACCGGGGGGGGAAGTCAATTGCAGGGGGTTCGCGAGCTGGCCGAGGTCATCCTCGACC
GCCAGGTGCGCCCCGGTCGGCCGCAACGGATCCGGGGGCTGGCCGACAGCACCTCGGGACCGGCTTTCGCGACCTGCGCC
GGGATGCTGCGCTATGCGGTTCAGCATCAGGTCGAAACCCCCGATACCGATCCGACCGCCGATGAGACGGTCGCGACAGG
AGCCCTGGGCCGGTTCGCCCGCTGGTGGAAGGACAACTTCTAA

Upstream 100 bases:

>100_bases
GTCGATCCCGAGGCCGAGATCGCCGGCGGCAAGCCGGCGCGCGGCGCCCCCGCCGGGGGACAAAAACCCCCACCGATAGT
TCGAAAGAGCGAGGGACGGG

Downstream 100 bases:

>100_bases
CGGTGGCGTCCAGGGCGCCGTAAGAGCGGTGCCGTCGATCCTCGGGAGCGGTGAGACGGTATCGATTTCGTGACTAGGGA
GCATGGGCTCCTCCCCGGCT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVLGVGHHRSRGMRNGQVANMDE
VELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVEMSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYA
IDGTEGVLDPRGMFGQSLGVSIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTT
SIAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILRVPLVGEDDEATANEVPRSML
VQIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQLQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCA
GMLRYAVQHQVETPDTDPTADETVATGALGRFARWWKDNF

Sequences:

>Translated_440_residues
MPRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVLGVGHHRSRGMRNGQVANMDE
VELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVEMSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYA
IDGTEGVLDPRGMFGQSLGVSIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTT
SIAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILRVPLVGEDDEATANEVPRSML
VQIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQLQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCA
GMLRYAVQHQVETPDTDPTADETVATGALGRFARWWKDNF
>Mature_439_residues
PRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVLGVGHHRSRGMRNGQVANMDEV
ELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVEMSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYAI
DGTEGVLDPRGMFGQSLGVSIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTTS
IAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILRVPLVGEDDEATANEVPRSMLV
QIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQLQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCAG
MLRYAVQHQVETPDTDPTADETVATGALGRFARWWKDNF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=421, Percent_Identity=33.0166270783848, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 47325; Mature: 47194

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVL
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCEEEEEECCCEEEEEEEEEECCCCCEEEE
GVGHHRSRGMRNGQVANMDEVELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVE
ECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEE
MSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYAIDGTEGVLDPRGMFGQSLGV
EEECCCEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHCCCCCCC
SIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTT
EEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCHHHCCEEEEEECCCCCCEEEEEECCCCE
SIAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILR
EEEEEECCEEEEEEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHEE
VPLVGEDDEATANEVPRSMLVQIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQ
ECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHH
LQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCAGMLRYAVQHQVETPDTDPTA
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DETVATGALGRFARWWKDNF
CHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVL
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCEEEEEECCCEEEEEEEEEECCCCCEEEE
GVGHHRSRGMRNGQVANMDEVELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVE
ECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEE
MSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYAIDGTEGVLDPRGMFGQSLGV
EEECCCEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHCCCCCCC
SIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTT
EEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCHHHCCEEEEEECCCCCCEEEEEECCCCE
SIAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILR
EEEEEECCEEEEEEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHEE
VPLVGEDDEATANEVPRSMLVQIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQ
ECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHH
LQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCAGMLRYAVQHQVETPDTDPTA
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DETVATGALGRFARWWKDNF
CHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]