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The map label for this gene is gltC [H]

Identifier: 83592143

GI number: 83592143

Start: 959326

End: 960291

Strand: Reverse

Name: gltC [H]

Synonym: Rru_A0804

Alternate gene names: 83592143

Gene position: 960291-959326 (Counterclockwise)

Preceding gene: 83592144

Following gene: 83592137

Centisome position: 22.06

GC content: 60.56

Gene sequence:

>966_bases
ATGGGTATCCGGGTTTCGACGATCAGCCGCTGCATCGGGCATCTGGAGGATGAGATCGGCGTCGCTCTGTTCCTCCGCCG
CCCCAATGGCGTGACACTCACCTTCGCCGGCGAGCAGTTCCTGGTTCGGGCGCGTCGAGCGATGACGGAAGTCAGGCATG
CGATCTGCGAGGCCGGAATTGCGGGCACAGGGCGGAACGGGTTCGTCCGCCTCGGCCTTCTGTCGTCGCTGGCCGCTCCG
TTCCCGGCCATGCTGATAAAAATCTACTGTGCGGCCTACCCCGGTGTGCGGATCCTCTATAGCGAAGGCGGCGCGGCCGA
TCATAGAGCGGCCCTCCAACACCACCGGCTTGACCTGGCTTTTCTGCCCCATCCGGAAAAGGCGGAGGGATGCGACGCCT
TGGGCCTTTGGGAAGAGCGCCTTTTTGCGGCGATGGCCCAGGACGATCCTCTCACGAGGCACGATGTCGTCACATGGGAC
GATCTGCGGGAACGCCATTTCATCTTCAGCGAGGTGCCGCCGGGACCCGAACTCCTGGATTACTTGACCGAACGCCTCGT
GGGATTCGGATTTCTGCTCAAAGCCGACTTGCTAACCGTCTACCGGGATACGGTGATGCGGGTTATCGCCAACGGTTCCG
ACGTGACCGTGATTGGCGAGGCGAGAGTCTCGCACCCGATTCAGGGGGTAGCATGTCGACCCATCACCGGCGAAAGCCTG
TTCTTTCACGCGGTGTGGCTGCCAACGAACGACAACCCCGCCTTTCGCCGCTTCCTCAGCTTGGCCAAGGTATTATCGAA
ACAATGTTCGGTCTGCGAGTTGAAAGAGGGACTTGCCGGACCTTCGGGCGAAGATCACAGCGTGATGGATGAAACGAGCG
CCAGCTTGGAACGAAAATCGCGTCTCCTCAAAATCGTGTCGGAACGATGCGCCACCTGCCTTCTCAAAAAGGCCATCGCC
GATTAG

Upstream 100 bases:

>100_bases
CTGGAATTGCACGCGACAGCCAGGACCTACATGGCTTCCGTCTCCTGGCAGTGTAATTGCCGTAGCCGAGCACGGAAGCT
TCCGGCGCGCGGCGGGGGCG

Downstream 100 bases:

>100_bases
AGTGCACGCGCCCCCAGTCGCGCCCCCGATTTCGTTTCTGATTTGCCCTACTCAGCGGAAAAACTTGACGGAGTGGCCAC
CGATTTTGCGACAGGACTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGIRVSTISRCIGHLEDEIGVALFLRRPNGVTLTFAGEQFLVRARRAMTEVRHAICEAGIAGTGRNGFVRLGLLSSLAAP
FPAMLIKIYCAAYPGVRILYSEGGAADHRAALQHHRLDLAFLPHPEKAEGCDALGLWEERLFAAMAQDDPLTRHDVVTWD
DLRERHFIFSEVPPGPELLDYLTERLVGFGFLLKADLLTVYRDTVMRVIANGSDVTVIGEARVSHPIQGVACRPITGESL
FFHAVWLPTNDNPAFRRFLSLAKVLSKQCSVCELKEGLAGPSGEDHSVMDETSASLERKSRLLKIVSERCATCLLKKAIA
D

Sequences:

>Translated_321_residues
MGIRVSTISRCIGHLEDEIGVALFLRRPNGVTLTFAGEQFLVRARRAMTEVRHAICEAGIAGTGRNGFVRLGLLSSLAAP
FPAMLIKIYCAAYPGVRILYSEGGAADHRAALQHHRLDLAFLPHPEKAEGCDALGLWEERLFAAMAQDDPLTRHDVVTWD
DLRERHFIFSEVPPGPELLDYLTERLVGFGFLLKADLLTVYRDTVMRVIANGSDVTVIGEARVSHPIQGVACRPITGESL
FFHAVWLPTNDNPAFRRFLSLAKVLSKQCSVCELKEGLAGPSGEDHSVMDETSASLERKSRLLKIVSERCATCLLKKAIA
D
>Mature_320_residues
GIRVSTISRCIGHLEDEIGVALFLRRPNGVTLTFAGEQFLVRARRAMTEVRHAICEAGIAGTGRNGFVRLGLLSSLAAPF
PAMLIKIYCAAYPGVRILYSEGGAADHRAALQHHRLDLAFLPHPEKAEGCDALGLWEERLFAAMAQDDPLTRHDVVTWDD
LRERHFIFSEVPPGPELLDYLTERLVGFGFLLKADLLTVYRDTVMRVIANGSDVTVIGEARVSHPIQGVACRPITGESLF
FHAVWLPTNDNPAFRRFLSLAKVLSKQCSVCELKEGLAGPSGEDHSVMDETSASLERKSRLLKIVSERCATCLLKKAIAD

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=231, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=222, Percent_Identity=27.9279279279279, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35332; Mature: 35201

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRVSTISRCIGHLEDEIGVALFLRRPNGVTLTFAGEQFLVRARRAMTEVRHAICEAGI
CCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
AGTGRNGFVRLGLLSSLAAPFPAMLIKIYCAAYPGVRILYSEGGAADHRAALQHHRLDLA
CCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCEE
FLPHPEKAEGCDALGLWEERLFAAMAQDDPLTRHDVVTWDDLRERHFIFSEVPPGPELLD
ECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCEEECCCCCCHHHHH
YLTERLVGFGFLLKADLLTVYRDTVMRVIANGSDVTVIGEARVSHPIQGVACRPITGESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCCCEEECCCCCCCE
FFHAVWLPTNDNPAFRRFLSLAKVLSKQCSVCELKEGLAGPSGEDHSVMDETSASLERKS
EEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RLLKIVSERCATCLLKKAIAD
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIRVSTISRCIGHLEDEIGVALFLRRPNGVTLTFAGEQFLVRARRAMTEVRHAICEAGI
CCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
AGTGRNGFVRLGLLSSLAAPFPAMLIKIYCAAYPGVRILYSEGGAADHRAALQHHRLDLA
CCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCEE
FLPHPEKAEGCDALGLWEERLFAAMAQDDPLTRHDVVTWDDLRERHFIFSEVPPGPELLD
ECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCEEECCCCCCHHHHH
YLTERLVGFGFLLKADLLTVYRDTVMRVIANGSDVTVIGEARVSHPIQGVACRPITGESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCCCEEECCCCCCCE
FFHAVWLPTNDNPAFRRFLSLAKVLSKQCSVCELKEGLAGPSGEDHSVMDETSASLERKS
EEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RLLKIVSERCATCLLKKAIAD
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]