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The map label for this gene is yciL [C]

Identifier: 83591991

GI number: 83591991

Start: 772842

End: 773723

Strand: Direct

Name: yciL [C]

Synonym: Rru_A0652

Alternate gene names: 83591991

Gene position: 772842-773723 (Clockwise)

Preceding gene: 83591990

Following gene: 83591992

Centisome position: 17.75

GC content: 69.05

Gene sequence:

>882_bases
ATGAGTGGGGATAGCGAACGGATCGCCAAGGTCATCGCCCGCGCCGGCATATGCTCGCGCCGCGATGCCGAAAAGCTGAT
CGTCGAGGGGCGGGTGACGCTCAACGGCCGCAAGGTCGAGACGCCGGCCACCCTGGTCGCCGCCAGCGATACGGTGACGG
TCGACGGCAAGCCGCTGCCCGCCCTCGAACCGGCCCGGCTGTGGCGTTACAACAAGCCGATCGGTCTGGTCACCAGCCAT
CGCGACGAACAGGGCCGGCCGACGGTGTTCGAGCGTCTGCCCGCCACCCTGCCCCGGGTGATTTCGGTGGGCCGCCTTGA
TCTCAACAGCGAAGGCTTGCTGCTGTTGACCAATGACGGCGAACTGGCCCGCCGGTTGGAACATCCCAGCCAGGGCTGGC
TGCGCCGCTACCGCGTGCGCGTGCATGGCGCCCCCGATCCGGTGAAACTGGCCGCCCTGGAAAAGGGCGTGACGGTGGAA
GGCGTGGCCTATGGCTCGATCCGCGTCGCCCTCGAACGCCAGCAAGGGGCCAATGCTTGGCTGTCGGTGTCGCTGCGCGA
GGGCAAGAACCGCGAAATCCGCCGGGTCATGGAGCATCTGGGGCTGCCGGTGTCGCGGCTGATCCGCGTCGCCTATGGCC
CGTTCCAGCTCGGCCAGCTTGAAGAGGGCACGGTCGACGAGATCCCGGGCAAGATCATGCGCGAGCAATTGGGCAAGGAC
GCCCCGCCGCCGCCGCGCCGCGCCGAAGCCAAGGCCAAGGGCAACAAAGGCGCCGCCCCGCCGCCCAAAGGAACGCTGAG
CCTGCCCGAATCCTCCAACACCGGTCGGGTGGCCCGCATCGCCCGCGCCACCCGGCGCGCCCATAAGCCGGAGCCGTCGT
AA

Upstream 100 bases:

>100_bases
TCTGTCTGGGGGTGCAATGGCACCCCGAATATGCCATCAGCGCGGCCGACACGGCGATCTTTGACGCCTTCGTCGCCGCA
AGCCGGGGGGGAGAGGGCGC

Downstream 100 bases:

>100_bases
TGCGCATCGTTGGCGGCCGGCTCAAGGGCAAGGTGCTGACCGCCCCGGTCGGCCCCGCCGTGCGGCCCACCGGGGATCGC
ACCCGGGAAGCGCTGTTCAA

Product: pseudouridine synthase, Rsu

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSGDSERIAKVIARAGICSRRDAEKLIVEGRVTLNGRKVETPATLVAASDTVTVDGKPLPALEPARLWRYNKPIGLVTSH
RDEQGRPTVFERLPATLPRVISVGRLDLNSEGLLLLTNDGELARRLEHPSQGWLRRYRVRVHGAPDPVKLAALEKGVTVE
GVAYGSIRVALERQQGANAWLSVSLREGKNREIRRVMEHLGLPVSRLIRVAYGPFQLGQLEEGTVDEIPGKIMREQLGKD
APPPPRRAEAKAKGNKGAAPPPKGTLSLPESSNTGRVARIARATRRAHKPEPS

Sequences:

>Translated_293_residues
MSGDSERIAKVIARAGICSRRDAEKLIVEGRVTLNGRKVETPATLVAASDTVTVDGKPLPALEPARLWRYNKPIGLVTSH
RDEQGRPTVFERLPATLPRVISVGRLDLNSEGLLLLTNDGELARRLEHPSQGWLRRYRVRVHGAPDPVKLAALEKGVTVE
GVAYGSIRVALERQQGANAWLSVSLREGKNREIRRVMEHLGLPVSRLIRVAYGPFQLGQLEEGTVDEIPGKIMREQLGKD
APPPPRRAEAKAKGNKGAAPPPKGTLSLPESSNTGRVARIARATRRAHKPEPS
>Mature_292_residues
SGDSERIAKVIARAGICSRRDAEKLIVEGRVTLNGRKVETPATLVAASDTVTVDGKPLPALEPARLWRYNKPIGLVTSHR
DEQGRPTVFERLPATLPRVISVGRLDLNSEGLLLLTNDGELARRLEHPSQGWLRRYRVRVHGAPDPVKLAALEKGVTVEG
VAYGSIRVALERQQGANAWLSVSLREGKNREIRRVMEHLGLPVSRLIRVAYGPFQLGQLEEGTVDEIPGKIMREQLGKDA
PPPPRRAEAKAKGNKGAAPPPKGTLSLPESSNTGRVARIARATRRAHKPEPS

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=219, Percent_Identity=44.2922374429224, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=36.9565217391304, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790453, Length=231, Percent_Identity=31.6017316017316, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788510, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 32012; Mature: 31881

Theoretical pI: Translated: 11.10; Mature: 11.10

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDSERIAKVIARAGICSRRDAEKLIVEGRVTLNGRKVETPATLVAASDTVTVDGKPLP
CCCCHHHHHHHHHHHCCCCCCCCHHEEEECEEEECCEEECCCEEEEEECCEEEECCCCCC
ALEPARLWRYNKPIGLVTSHRDEQGRPTVFERLPATLPRVISVGRLDLNSEGLLLLTNDG
CCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCH
ELARRLEHPSQGWLRRYRVRVHGAPDPVKLAALEKGVTVEGVAYGSIRVALERQQGANAW
HHHHHHCCCCHHHHHEEEEEECCCCCCEEEEEHHCCCEEEEEEECEEEEEEECCCCCCEE
LSVSLREGKNREIRRVMEHLGLPVSRLIRVAYGPFQLGQLEEGTVDEIPGKIMREQLGKD
EEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHCCC
APPPPRRAEAKAKGNKGAAPPPKGTLSLPESSNTGRVARIARATRRAHKPEPS
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGDSERIAKVIARAGICSRRDAEKLIVEGRVTLNGRKVETPATLVAASDTVTVDGKPLP
CCCHHHHHHHHHHHCCCCCCCCHHEEEECEEEECCEEECCCEEEEEECCEEEECCCCCC
ALEPARLWRYNKPIGLVTSHRDEQGRPTVFERLPATLPRVISVGRLDLNSEGLLLLTNDG
CCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCH
ELARRLEHPSQGWLRRYRVRVHGAPDPVKLAALEKGVTVEGVAYGSIRVALERQQGANAW
HHHHHHCCCCHHHHHEEEEEECCCCCCEEEEEHHCCCEEEEEEECEEEEEEECCCCCCEE
LSVSLREGKNREIRRVMEHLGLPVSRLIRVAYGPFQLGQLEEGTVDEIPGKIMREQLGKD
EEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHCCC
APPPPRRAEAKAKGNKGAAPPPKGTLSLPESSNTGRVARIARATRRAHKPEPS
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA