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The map label for this gene is ubiA [H]

Identifier: 83591911

GI number: 83591911

Start: 679120

End: 680043

Strand: Direct

Name: ubiA [H]

Synonym: Rru_A0572

Alternate gene names: 83591911

Gene position: 679120-680043 (Clockwise)

Preceding gene: 83591906

Following gene: 83591912

Centisome position: 15.6

GC content: 66.13

Gene sequence:

>924_bases
ATGGGCGCGAGCGACACGCTGATCGGCGATATGCCGCGGGATGGCTGGGTCGACCGGATGGCTCCGGGGGTGATCCGGCC
TTATCTGAAACTGATGCGGCTTGATCGGCCGATCGGCACGTGGCTGCTGTTGTTTCCCTGCTGGTGGAGCCAGTCGATGG
CCGCGCAGGGCTGGCCCGATCTGTGGCTGGCCGCCCTGTTCGCCGCCGGCGCTTTGGTCATGCGCGGCGCGGGCTGCACC
TTCAACGATATCGTCGACCGGGATTTCGATGCCCAGGTGGCGCGCACCGCCGCCCGGCCGATTCCCAGCGGCGCCGTCAG
TCGCAAAAAGGCGGTGGTCTTTCTGGGCGCGCAGTTGCTGGTCGGGCTGGCGGTGCTGCTCAGCCTCAACGGCTTTTCGA
TCTGGCTGGGCGTCGCCTCGTTGATCTTGGTCTTTGGTTATCCCTTCATGAAGCGCATCACCTACTGGCCGCAGGCGTGG
CTGGGGCTGACCTTCACCTATGGGGCGCTGATGGGCTGGGCGGCGGTGCGCGGATCGCTTGATCCGGCGCCCTTGCTGCT
CTATGCCGCCTGCTTCTTCTGGACCCTGCATTACGACACCATCTATGCCCATCAGGACAAAGAAGACGACCTGCTGGTCG
GGGTGAAATCCTCGGCCCTGGCCCTGGGGTCGAACACCCGTCCGGCCCTGGTGGTGTTTTCCACCCTGATGATGGCGCTG
GTCGCCGCCGCCGGCTGGCAGGCCGGCTTGTCCTGGCCGTTCTGGGCGCTGCTGGGTCTGCCCGCCGCCCATCTGGCTTG
GCAGATCTGGCGGGTCGATATTCATGACTCGCCCGTCTGCCTTATGATCTTCAAGAGCAACCGGTTCGTCGGATGGCTCC
TGCTGGCGGCGATCGTCGCCGGGCGGGCGCCCGGTGGCGTCTGA

Upstream 100 bases:

>100_bases
GGGTGGCGGACACCATACTGTACCGGCTATAAGGGGCAAGTCTGGGCTGAGAGCTGCTCTAGCCAGACAAGGCGATGAAA
AAACAACGGACGGAACGAGC

Downstream 100 bases:

>100_bases
CCCCAACGCCTTCGTTCTGGCCGGAACCGCCATCACCACCCCGCCGCTCCTCCCCGAGATGAGCCTGTATCTGGCGACCG
AGGTCACCCCGCTGTGGGAG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MGASDTLIGDMPRDGWVDRMAPGVIRPYLKLMRLDRPIGTWLLLFPCWWSQSMAAQGWPDLWLAALFAAGALVMRGAGCT
FNDIVDRDFDAQVARTAARPIPSGAVSRKKAVVFLGAQLLVGLAVLLSLNGFSIWLGVASLILVFGYPFMKRITYWPQAW
LGLTFTYGALMGWAAVRGSLDPAPLLLYAACFFWTLHYDTIYAHQDKEDDLLVGVKSSALALGSNTRPALVVFSTLMMAL
VAAAGWQAGLSWPFWALLGLPAAHLAWQIWRVDIHDSPVCLMIFKSNRFVGWLLLAAIVAGRAPGGV

Sequences:

>Translated_307_residues
MGASDTLIGDMPRDGWVDRMAPGVIRPYLKLMRLDRPIGTWLLLFPCWWSQSMAAQGWPDLWLAALFAAGALVMRGAGCT
FNDIVDRDFDAQVARTAARPIPSGAVSRKKAVVFLGAQLLVGLAVLLSLNGFSIWLGVASLILVFGYPFMKRITYWPQAW
LGLTFTYGALMGWAAVRGSLDPAPLLLYAACFFWTLHYDTIYAHQDKEDDLLVGVKSSALALGSNTRPALVVFSTLMMAL
VAAAGWQAGLSWPFWALLGLPAAHLAWQIWRVDIHDSPVCLMIFKSNRFVGWLLLAAIVAGRAPGGV
>Mature_306_residues
GASDTLIGDMPRDGWVDRMAPGVIRPYLKLMRLDRPIGTWLLLFPCWWSQSMAAQGWPDLWLAALFAAGALVMRGAGCTF
NDIVDRDFDAQVARTAARPIPSGAVSRKKAVVFLGAQLLVGLAVLLSLNGFSIWLGVASLILVFGYPFMKRITYWPQAWL
GLTFTYGALMGWAAVRGSLDPAPLLLYAACFFWTLHYDTIYAHQDKEDDLLVGVKSSALALGSNTRPALVVFSTLMMALV
AAAGWQAGLSWPFWALLGLPAAHLAWQIWRVDIHDSPVCLMIFKSNRFVGWLLLAAIVAGRAPGGV

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=285, Percent_Identity=52.6315789473684, Blast_Score=291, Evalue=7e-79,
Organism=Escherichia coli, GI1790473, Length=268, Percent_Identity=38.0597014925373, Blast_Score=174, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=48.2394366197183, Blast_Score=253, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI32565247, Length=284, Percent_Identity=44.7183098591549, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17553720, Length=343, Percent_Identity=36.734693877551, Blast_Score=200, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI32565245, Length=144, Percent_Identity=50, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=50, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=44.7457627118644, Blast_Score=219, Evalue=5e-58,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=51.6129032258064, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33555; Mature: 33424

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASDTLIGDMPRDGWVDRMAPGVIRPYLKLMRLDRPIGTWLLLFPCWWSQSMAAQGWPD
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHH
LWLAALFAAGALVMRGAGCTFNDIVDRDFDAQVARTAARPIPSGAVSRKKAVVFLGAQLL
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHEEEHHHHH
VGLAVLLSLNGFSIWLGVASLILVFGYPFMKRITYWPQAWLGLTFTYGALMGWAAVRGSL
HHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DPAPLLLYAACFFWTLHYDTIYAHQDKEDDLLVGVKSSALALGSNTRPALVVFSTLMMAL
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHH
VAAAGWQAGLSWPFWALLGLPAAHLAWQIWRVDIHDSPVCLMIFKSNRFVGWLLLAAIVA
HHHHCCCCCCCCHHHHHHCCCHHHHEEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHH
GRAPGGV
CCCCCCC
>Mature Secondary Structure 
GASDTLIGDMPRDGWVDRMAPGVIRPYLKLMRLDRPIGTWLLLFPCWWSQSMAAQGWPD
CCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHH
LWLAALFAAGALVMRGAGCTFNDIVDRDFDAQVARTAARPIPSGAVSRKKAVVFLGAQLL
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHEEEHHHHH
VGLAVLLSLNGFSIWLGVASLILVFGYPFMKRITYWPQAWLGLTFTYGALMGWAAVRGSL
HHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DPAPLLLYAACFFWTLHYDTIYAHQDKEDDLLVGVKSSALALGSNTRPALVVFSTLMMAL
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHH
VAAAGWQAGLSWPFWALLGLPAAHLAWQIWRVDIHDSPVCLMIFKSNRFVGWLLLAAIVA
HHHHCCCCCCCCHHHHHHCCCHHHHEEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHH
GRAPGGV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA