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The map label for this gene is pleC [H]

Identifier: 83591406

GI number: 83591406

Start: 76073

End: 78394

Strand: Direct

Name: pleC [H]

Synonym: Rru_A0066

Alternate gene names: 83591406

Gene position: 76073-78394 (Clockwise)

Preceding gene: 83591400

Following gene: 83591407

Centisome position: 1.75

GC content: 66.67

Gene sequence:

>2322_bases
ATGATCAAATGGTCCTCTTTTCGTCTTGAAAAAATGGAGGCTGATGTGGGTCGGCAGGACCATTCTCCGCAGTCTCTTGC
CGTCTTGCGCAGCCACCCGATGGTCCGCGCCATTCTTGACGCCCTGACCCTGCCCGCGGCGGTGATCATGGCCCGCGACG
GCCGGGTTCTCGAGGGCAACGCCGCCTTCTTCGAGGCCCTGGGCCGGCCGGCCGACGCCGTGCTCGACCATCCCGCCCCC
TTTGACGTGTCGATCGCCGACGCGGCGGCGACGGCCGGCGGCCCGGCCAGCCCTCCGCCCTCGCGCCGGCGCTGTGCTTT
CCTGCGCGCCGATGGCGTTCTCGTTCAGGCCACCTTGGGGGTTGGCGTTCTGGAAGGGGTGGCCGGGCTGGTGCTGGTCA
CCCTGGATGGCATCGCCGGGGCCGATGGCTGTCCGCTGCGCCGACGGGCCGAAGCGACGGTGCCCTGCGCCGCCGACCGC
TTCCGCTCGCTTTTCGATCTGGCGCCGATCGGCATGGCGATGCTCGATGGCGAGCGCCGCTGGCGACAGGCCAATAGCGT
GATGTGCCGGCTGCTGGGTGTTCCCTTCGAAGGGTTGGCCGCGAAGCGCTGGTCCGATAGCGTCCACCCCGAAGACCGCG
GCCGTGACGAACGCTTTTTCGCCAGTCTGCTGCGGAACGACGACAAGGCCAGCACCACCAATCTGCGGCTGGTCGCCGCC
GATGGCCGGGTGGTGCCGGTCACCCTGTCGCTGGGCGTGATGCGCGATGGACCGAAGGGGCAGTCCGACCAGATCCTTGT
GCTGGTCCAAGACATTTCCGAACGGGTGGACTGGGAAGCGACCAAGGCCGAGAACGAGGCCCGGCTGCGTTCGCTGATCA
ACGCCACCACCGATGCGATTTTCCTGCTTGATCCCGATGGTGCCATCCGGGTCATCAACCGCGCCGGAGCCCGGTTGCTG
GGCACCACGGCGCGGGCGGCGGCGGGCCGCAGCTTCTATGAGTTCCTCGACGCTCCGCAGGCGACGGAGCGACGCGCCCT
GTTTGGCGAAGTGCTGGCGACCCTGCTGCCGGTCAACGGCATCGAGCGCTGGGGCGAGCGTTGGCTCGATATGGTGGTTT
TTCCGGTGGTCGACGGCGATGGCAAGGCGATGGGGGTGACGCTGTTCACCCGCGATATCACCTCGCGCCGCGAAGCCGAG
GACCGGGCGCGGGCCGCCGAGCGCCATCTGCTTGAGGCCACCGAACTGATGTCGGCGGCGATGCTGCTGTTCGACCCCCA
GGGTATTCTGGTCTTGATCAACTCCGCCTGCCGGGCCGCCCTGCCCGACCTGGAGGACATCCTTCATCCCGGCCTGAGCT
TTATCGAACTGCGCGCCGCCATCGTCGCCCGCCGGTTGTTTGTCCAGGCGATCACCGAGTCGCAGGGCGGGATCAAGGGC
GGAACGCCCGGTCCGGCGCCGATCGAGGTCCGCGGCAAGGACGGGCGGTGGCTGTTGATACGCCAGAGCGCGACCTCAAG
CGGCTATACCCTGATCCTGGGCACCGATATCACCGAATTGAAACGGCGCGAGCGGGCCTTGGCCGATGCCAAGGAAGTCG
CCGAATACGCCAACCGGGCCAAAAGCGAGTTTCTGGCCAATATGAGCCATGAACTGCGCACGCCGCTCAACGCCATCATC
GGTTTTTCCGATATCACCCGCCATCAGATGTTCGGGCGGCTCGATAACCCGGTCTATGTGGATTACGCCCGCAACATCTA
TGACTCGGGCACGCATCTGCTGGAGATCATCAGCGATATCCTGGATCTGGCCAAGATCGAGGCCGGCGAACTGGGGCTCG
ACGAGGAGGAGGTCGATGCCGCCCGTCTGGTCGACAGCGCCATCCAGATGGTGACGCCGCGCGCCACGTCCAAACGCATC
GCCTTGACCAACCTGCTGACCGGCGATCTGCCCCGCTTGTGGTGCGATCCCTTGCGACTCAAGCAGGTGCTGATCAACCT
GTTGTCCAATGCCGTCAAATACACCCAGGAAGACGGGGCGGTGGCGGTGACCGCCCGGCTGGCCGGCGGGGACGGTCTGG
CGATTTCGGTGATCGACACCGGCATCGGCATGGACGAGGCCGGCATTCAGGTGGCGATGACCGCCTTTGGTCAGGTCGAA
AGCCCCTATTCCCGCCGCCAGGGCGGCACCGGCCTGGGCTTGCCGCTGACCCGCAAGCTGACCGAGGCCCATCAGGGGTG
TTTGACCATCGCCAGCCGCCCGGGCGAGGGCACGACGGTGACCATCCTGCTGCCCGCCCATCGCCTGCGGGCCGCTTCTT
AG

Upstream 100 bases:

>100_bases
ACCGGTAATCACCGGTGAAGGGATCGTCCAAGTCGGCGGCCTTCACCCCTTGGCCGGAGCGGGGTGTTTTCCATCGTTTC
CTGGCGAAGGGGCGTGGGAT

Downstream 100 bases:

>100_bases
CCGTGAGGGCGGCGCGCTGGACGGCCGAGGCGGCCGATTTGCCCGCCGTCGCCGGAGCCTATCTGCTGCTGATCGATCTG
GCGCGGCCGGTGGCGTTGGC

Product: PAS/PAC sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MIKWSSFRLEKMEADVGRQDHSPQSLAVLRSHPMVRAILDALTLPAAVIMARDGRVLEGNAAFFEALGRPADAVLDHPAP
FDVSIADAAATAGGPASPPPSRRRCAFLRADGVLVQATLGVGVLEGVAGLVLVTLDGIAGADGCPLRRRAEATVPCAADR
FRSLFDLAPIGMAMLDGERRWRQANSVMCRLLGVPFEGLAAKRWSDSVHPEDRGRDERFFASLLRNDDKASTTNLRLVAA
DGRVVPVTLSLGVMRDGPKGQSDQILVLVQDISERVDWEATKAENEARLRSLINATTDAIFLLDPDGAIRVINRAGARLL
GTTARAAAGRSFYEFLDAPQATERRALFGEVLATLLPVNGIERWGERWLDMVVFPVVDGDGKAMGVTLFTRDITSRREAE
DRARAAERHLLEATELMSAAMLLFDPQGILVLINSACRAALPDLEDILHPGLSFIELRAAIVARRLFVQAITESQGGIKG
GTPGPAPIEVRGKDGRWLLIRQSATSSGYTLILGTDITELKRRERALADAKEVAEYANRAKSEFLANMSHELRTPLNAII
GFSDITRHQMFGRLDNPVYVDYARNIYDSGTHLLEIISDILDLAKIEAGELGLDEEEVDAARLVDSAIQMVTPRATSKRI
ALTNLLTGDLPRLWCDPLRLKQVLINLLSNAVKYTQEDGAVAVTARLAGGDGLAISVIDTGIGMDEAGIQVAMTAFGQVE
SPYSRRQGGTGLGLPLTRKLTEAHQGCLTIASRPGEGTTVTILLPAHRLRAAS

Sequences:

>Translated_773_residues
MIKWSSFRLEKMEADVGRQDHSPQSLAVLRSHPMVRAILDALTLPAAVIMARDGRVLEGNAAFFEALGRPADAVLDHPAP
FDVSIADAAATAGGPASPPPSRRRCAFLRADGVLVQATLGVGVLEGVAGLVLVTLDGIAGADGCPLRRRAEATVPCAADR
FRSLFDLAPIGMAMLDGERRWRQANSVMCRLLGVPFEGLAAKRWSDSVHPEDRGRDERFFASLLRNDDKASTTNLRLVAA
DGRVVPVTLSLGVMRDGPKGQSDQILVLVQDISERVDWEATKAENEARLRSLINATTDAIFLLDPDGAIRVINRAGARLL
GTTARAAAGRSFYEFLDAPQATERRALFGEVLATLLPVNGIERWGERWLDMVVFPVVDGDGKAMGVTLFTRDITSRREAE
DRARAAERHLLEATELMSAAMLLFDPQGILVLINSACRAALPDLEDILHPGLSFIELRAAIVARRLFVQAITESQGGIKG
GTPGPAPIEVRGKDGRWLLIRQSATSSGYTLILGTDITELKRRERALADAKEVAEYANRAKSEFLANMSHELRTPLNAII
GFSDITRHQMFGRLDNPVYVDYARNIYDSGTHLLEIISDILDLAKIEAGELGLDEEEVDAARLVDSAIQMVTPRATSKRI
ALTNLLTGDLPRLWCDPLRLKQVLINLLSNAVKYTQEDGAVAVTARLAGGDGLAISVIDTGIGMDEAGIQVAMTAFGQVE
SPYSRRQGGTGLGLPLTRKLTEAHQGCLTIASRPGEGTTVTILLPAHRLRAAS
>Mature_773_residues
MIKWSSFRLEKMEADVGRQDHSPQSLAVLRSHPMVRAILDALTLPAAVIMARDGRVLEGNAAFFEALGRPADAVLDHPAP
FDVSIADAAATAGGPASPPPSRRRCAFLRADGVLVQATLGVGVLEGVAGLVLVTLDGIAGADGCPLRRRAEATVPCAADR
FRSLFDLAPIGMAMLDGERRWRQANSVMCRLLGVPFEGLAAKRWSDSVHPEDRGRDERFFASLLRNDDKASTTNLRLVAA
DGRVVPVTLSLGVMRDGPKGQSDQILVLVQDISERVDWEATKAENEARLRSLINATTDAIFLLDPDGAIRVINRAGARLL
GTTARAAAGRSFYEFLDAPQATERRALFGEVLATLLPVNGIERWGERWLDMVVFPVVDGDGKAMGVTLFTRDITSRREAE
DRARAAERHLLEATELMSAAMLLFDPQGILVLINSACRAALPDLEDILHPGLSFIELRAAIVARRLFVQAITESQGGIKG
GTPGPAPIEVRGKDGRWLLIRQSATSSGYTLILGTDITELKRRERALADAKEVAEYANRAKSEFLANMSHELRTPLNAII
GFSDITRHQMFGRLDNPVYVDYARNIYDSGTHLLEIISDILDLAKIEAGELGLDEEEVDAARLVDSAIQMVTPRATSKRI
ALTNLLTGDLPRLWCDPLRLKQVLINLLSNAVKYTQEDGAVAVTARLAGGDGLAISVIDTGIGMDEAGIQVAMTAFGQVE
SPYSRRQGGTGLGLPLTRKLTEAHQGCLTIASRPGEGTTVTILLPAHRLRAAS

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=39.3162393162393, Blast_Score=149, Evalue=8e-37,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=36.078431372549, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1788713, Length=279, Percent_Identity=35.84229390681, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=38.4297520661157, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=35.1351351351351, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=28.2352941176471, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=262, Percent_Identity=29.7709923664122, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786912, Length=297, Percent_Identity=28.956228956229, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1786600, Length=282, Percent_Identity=26.5957446808511, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=27.7992277992278, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=28.2608695652174, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=26.6375545851528, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=25.1968503937008, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.1082251082251, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83527; Mature: 83527

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWSSFRLEKMEADVGRQDHSPQSLAVLRSHPMVRAILDALTLPAAVIMARDGRVLEGN
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCEEEECC
AAFFEALGRPADAVLDHPAPFDVSIADAAATAGGPASPPPSRRRCAFLRADGVLVQATLG
HHHHHHHCCCHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCHHCEEEEEECCEEEEEEHH
VGVLEGVAGLVLVTLDGIAGADGCPLRRRAEATVPCAADRFRSLFDLAPIGMAMLDGERR
HHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WRQANSVMCRLLGVPFEGLAAKRWSDSVHPEDRGRDERFFASLLRNDDKASTTNLRLVAA
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEE
DGRVVPVTLSLGVMRDGPKGQSDQILVLVQDISERVDWEATKAENEARLRSLINATTDAI
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCHHCCCHHHHHHHHHHCCCCEE
FLLDPDGAIRVINRAGARLLGTTARAAAGRSFYEFLDAPQATERRALFGEVLATLLPVNG
EEECCCCCEEHHHHCCCHHHCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
IERWGERWLDMVVFPVVDGDGKAMGVTLFTRDITSRREAEDRARAAERHLLEATELMSAA
HHHHHHHHHHEEEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLFDPQGILVLINSACRAALPDLEDILHPGLSFIELRAAIVARRLFVQAITESQGGIKG
HHHCCCCCEEEEEEHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPGPAPIEVRGKDGRWLLIRQSATSSGYTLILGTDITELKRRERALADAKEVAEYANRA
CCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KSEFLANMSHELRTPLNAIIGFSDITRHQMFGRLDNPVYVDYARNIYDSGTHLLEIISDI
HHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHH
LDLAKIEAGELGLDEEEVDAARLVDSAIQMVTPRATSKRIALTNLLTGDLPRLWCDPLRL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCHHHHCCHHHH
KQVLINLLSNAVKYTQEDGAVAVTARLAGGDGLAISVIDTGIGMDEAGIQVAMTAFGQVE
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEHHHHHCCCC
SPYSRRQGGTGLGLPLTRKLTEAHQGCLTIASRPGEGTTVTILLPAHRLRAAS
CCHHHCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEEECHHHHCCCC
>Mature Secondary Structure
MIKWSSFRLEKMEADVGRQDHSPQSLAVLRSHPMVRAILDALTLPAAVIMARDGRVLEGN
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCEEEECC
AAFFEALGRPADAVLDHPAPFDVSIADAAATAGGPASPPPSRRRCAFLRADGVLVQATLG
HHHHHHHCCCHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCHHCEEEEEECCEEEEEEHH
VGVLEGVAGLVLVTLDGIAGADGCPLRRRAEATVPCAADRFRSLFDLAPIGMAMLDGERR
HHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WRQANSVMCRLLGVPFEGLAAKRWSDSVHPEDRGRDERFFASLLRNDDKASTTNLRLVAA
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEE
DGRVVPVTLSLGVMRDGPKGQSDQILVLVQDISERVDWEATKAENEARLRSLINATTDAI
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCHHCCCHHHHHHHHHHCCCCEE
FLLDPDGAIRVINRAGARLLGTTARAAAGRSFYEFLDAPQATERRALFGEVLATLLPVNG
EEECCCCCEEHHHHCCCHHHCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
IERWGERWLDMVVFPVVDGDGKAMGVTLFTRDITSRREAEDRARAAERHLLEATELMSAA
HHHHHHHHHHEEEEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLFDPQGILVLINSACRAALPDLEDILHPGLSFIELRAAIVARRLFVQAITESQGGIKG
HHHCCCCCEEEEEEHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPGPAPIEVRGKDGRWLLIRQSATSSGYTLILGTDITELKRRERALADAKEVAEYANRA
CCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KSEFLANMSHELRTPLNAIIGFSDITRHQMFGRLDNPVYVDYARNIYDSGTHLLEIISDI
HHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHH
LDLAKIEAGELGLDEEEVDAARLVDSAIQMVTPRATSKRIALTNLLTGDLPRLWCDPLRL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCHHHHCCHHHH
KQVLINLLSNAVKYTQEDGAVAVTARLAGGDGLAISVIDTGIGMDEAGIQVAMTAFGQVE
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEHHHHHCCCC
SPYSRRQGGTGLGLPLTRKLTEAHQGCLTIASRPGEGTTVTILLPAHRLRAAS
CCHHHCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]