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The map label for this gene is trpS [H]

Identifier: 83313507

GI number: 83313507

Start: 4811880

End: 4812686

Strand: Reverse

Name: trpS [H]

Synonym: amb4408

Alternate gene names: 83313507

Gene position: 4812686-4811880 (Counterclockwise)

Preceding gene: 83313508

Following gene: 83313506

Centisome position: 96.89

GC content: 63.07

Gene sequence:

>807_bases
ATGATCGCCGCCGGCGTCGATCCGGCCAAGCACATCGTCTTCAACCAGTCCATGGTTCCGGCCCATGCCCAGTTGGCCTG
GATCTTCAATTGCGTCGCGCGCATGGGCTGGCTGAACCGCATGACCCAGTTCAAGGACAAGGCGGGCAAGCACAAGGAGA
ACGCCTCGGTCGGGCTGTTCGCCTATCCCAACCTGATGAGCGCCGACATCCTGACCTACAAGGCCACCCATGTGCCGGTG
GGCGAGGACCAGAAGCAGCATCTGGAACTGGCCCGCGACACCGCCCAGAAGTTCAACAACGATTTCGGCGTCGAGTTCTT
CCCGCTGCCCGAGCCCATCATTCCGCCCGAGGCGGCGCGCATCATGAGCTTGCGCGACGGGTCCAAGAAGATGAGCAAGT
CCGACGAGTCCGATTACTCGCGCATCAACATGACCGACGATGCCGACACCATCGCCCTGAAGATCCGCAAGGCCAAGACC
GACCTGGAGCCCCTGCCCGGCGCCATGGAAGGGCTTGAAGGCCGTCCCGAGGCTTCCAACCTGCTGGGGATCTACGCCGC
GCTGTCCGGCAAGGAGAAGGCCCAGGTGGTGACCCAGTTCGAAGGCCAGCAGTTCTCGGACTTCAAGAAGGAATTGGTGG
ACCTGGCCGTCTCGGTGCTGGGCCCCATCAATACCGAGATGAAGCGCCTGATGACCGATACCGCTCATATCGACGCCGTC
CTGCGCTCGGGTGCCGAACGGGCCGACGCCATCGCGGCGCCGATCATCAAGGACGTCTACGACATCGTCGGGTTCCTGCG
GCCGTGA

Upstream 100 bases:

>100_bases
CGCGTACGAGTGCATCTTCTGCATCGTCGATATGCATGCCATCACCTTGTGGCAGGACCCCAAGGAGCTGACCCGCAACA
TCCGCGAGGTCACCGCCGGC

Downstream 100 bases:

>100_bases
CCCAGCGCTTCGCCGAAACCCTGCTGAACGCCGTCGCCGCCGCCCTGGCGGGCGTGGCCGCCGTGCTGCGCCATCCGTCG
CGCCGTTTCGTCCTGTGGGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MIAAGVDPAKHIVFNQSMVPAHAQLAWIFNCVARMGWLNRMTQFKDKAGKHKENASVGLFAYPNLMSADILTYKATHVPV
GEDQKQHLELARDTAQKFNNDFGVEFFPLPEPIIPPEAARIMSLRDGSKKMSKSDESDYSRINMTDDADTIALKIRKAKT
DLEPLPGAMEGLEGRPEASNLLGIYAALSGKEKAQVVTQFEGQQFSDFKKELVDLAVSVLGPINTEMKRLMTDTAHIDAV
LRSGAERADAIAAPIIKDVYDIVGFLRP

Sequences:

>Translated_268_residues
MIAAGVDPAKHIVFNQSMVPAHAQLAWIFNCVARMGWLNRMTQFKDKAGKHKENASVGLFAYPNLMSADILTYKATHVPV
GEDQKQHLELARDTAQKFNNDFGVEFFPLPEPIIPPEAARIMSLRDGSKKMSKSDESDYSRINMTDDADTIALKIRKAKT
DLEPLPGAMEGLEGRPEASNLLGIYAALSGKEKAQVVTQFEGQQFSDFKKELVDLAVSVLGPINTEMKRLMTDTAHIDAV
LRSGAERADAIAAPIIKDVYDIVGFLRP
>Mature_268_residues
MIAAGVDPAKHIVFNQSMVPAHAQLAWIFNCVARMGWLNRMTQFKDKAGKHKENASVGLFAYPNLMSADILTYKATHVPV
GEDQKQHLELARDTAQKFNNDFGVEFFPLPEPIIPPEAARIMSLRDGSKKMSKSDESDYSRINMTDDADTIALKIRKAKT
DLEPLPGAMEGLEGRPEASNLLGIYAALSGKEKAQVVTQFEGQQFSDFKKELVDLAVSVLGPINTEMKRLMTDTAHIDAV
LRSGAERADAIAAPIIKDVYDIVGFLRP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=266, Percent_Identity=40.6015037593985, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI41352700, Length=114, Percent_Identity=52.6315789473684, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1789786, Length=265, Percent_Identity=44.5283018867925, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71982800, Length=267, Percent_Identity=38.2022471910112, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71982793, Length=267, Percent_Identity=38.2022471910112, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6320474, Length=279, Percent_Identity=38.3512544802867, Blast_Score=176, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24666151, Length=270, Percent_Identity=36.6666666666667, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 29544; Mature: 29544

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAGVDPAKHIVFNQSMVPAHAQLAWIFNCVARMGWLNRMTQFKDKAGKHKENASVGLF
CCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AYPNLMSADILTYKATHVPVGEDQKQHLELARDTAQKFNNDFGVEFFPLPEPIIPPEAAR
ECCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
IMSLRDGSKKMSKSDESDYSRINMTDDADTIALKIRKAKTDLEPLPGAMEGLEGRPEASN
HHHHCCCHHHHHCCCCCCCCEECCCCCCCEEEEEEEHHHCCCCCCCCHHHCCCCCCCHHH
LLGIYAALSGKEKAQVVTQFEGQQFSDFKKELVDLAVSVLGPINTEMKRLMTDTAHIDAV
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRSGAERADAIAAPIIKDVYDIVGFLRP
HHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAAGVDPAKHIVFNQSMVPAHAQLAWIFNCVARMGWLNRMTQFKDKAGKHKENASVGLF
CCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AYPNLMSADILTYKATHVPVGEDQKQHLELARDTAQKFNNDFGVEFFPLPEPIIPPEAAR
ECCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
IMSLRDGSKKMSKSDESDYSRINMTDDADTIALKIRKAKTDLEPLPGAMEGLEGRPEASN
HHHHCCCHHHHHCCCCCCCCEECCCCCCCEEEEEEEHHHCCCCCCCCHHHCCCCCCCHHH
LLGIYAALSGKEKAQVVTQFEGQQFSDFKKELVDLAVSVLGPINTEMKRLMTDTAHIDAV
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRSGAERADAIAAPIIKDVYDIVGFLRP
HHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]