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The map label for this gene is hdfR [H]

Identifier: 83313440

GI number: 83313440

Start: 4745486

End: 4746343

Strand: Reverse

Name: hdfR [H]

Synonym: amb4341

Alternate gene names: 83313440

Gene position: 4746343-4745486 (Counterclockwise)

Preceding gene: 83313441

Following gene: 83313439

Centisome position: 95.55

GC content: 65.5

Gene sequence:

>858_bases
ATGAATATCGATCTCGCCCGCACCTTCCTGGAAATCGTCGACACCGGAAACTTCAACAAGGCCGCCGAGCGATTGTCGGT
GACCCAGTCGACGGTCAGCATGCGCATCCGCGCCCTGGAGGAAGAGCTGGGGCGGCCGTTGTTCGTGCGCTCAAAATCGG
GCACCCAGTTGACCGCGGCCGGCATGCAGTTTCGCCGCTATGCCACCACCATGGTCCGGGTCTGGGAGCAGGCGCGCCAG
GAACTGGCCCTGCCGGCGGGATTTCGCACCGTGCTGAACGTGGGTGGCCAGTTCTCCCTGTGGGACCGCCTGCTGGTCCA
GTGGATTCCCTGGATGCGCACCGCCATGCCCGACGTGGCGCTGAAGGCCGAGGTCGGGGGATCTGACAGTCTGATGCGCC
AGCTGATCGAGGGCATGCTGGATCTGGTGGTGATGTATTCGCCGCTGTCGCGTCCGGGCCTGCACATCGAGAAGCTGCTG
GAAGAGCGTTTGGTCCTGGTTTCTACCCGGCGGCGCGCCGTGGCGGAATGGGACGAGGATTACGTTCTGGTGGACTGGGG
GCCGGAATTCCGCGCCGCCCACAGTCAGGCTTTTCCCGATCTCAAGACGCCGGCGGTCCAGGTGGGCTTGGGGGCCTTGG
GGCTGCAACACGTCCTGGCCTATGGCGGCACCGGCTATTTCCCCATGCGGGTGGTGCGCTCGTACCTGTCGGCGGGCCGG
CTGTTCGAAGTCACCGGGGCGCCGGAATTCCGCCGCCCGGCCTATCTGGTCCACGCCGAGGACGAAACCCGCGAGGACTG
GTTCGACACCGCGCTGGACGGCTTGCGCTATGTCGCCTCGCTGGAAAATGAGGACTGA

Upstream 100 bases:

>100_bases
CGATTACCAGCCGCGGGGTAGTTGAAGTTTCCGCGCGGTTCGGATAAAACGCTGCTTCTATTGCAGCGCAGCATAATGCT
GCCTCCGTTCTGGCCGCATC

Downstream 100 bases:

>100_bases
CCGTCCCCGTTTTTTCCCTAATCAGTGCTCATGGTTGTGGCCGCCGAGGTCTTCCTCGGCGTGCTTATGCTCGTGCGGCT
TCCAGGCGTGCTTGGCCTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNIDLARTFLEIVDTGNFNKAAERLSVTQSTVSMRIRALEEELGRPLFVRSKSGTQLTAAGMQFRRYATTMVRVWEQARQ
ELALPAGFRTVLNVGGQFSLWDRLLVQWIPWMRTAMPDVALKAEVGGSDSLMRQLIEGMLDLVVMYSPLSRPGLHIEKLL
EERLVLVSTRRRAVAEWDEDYVLVDWGPEFRAAHSQAFPDLKTPAVQVGLGALGLQHVLAYGGTGYFPMRVVRSYLSAGR
LFEVTGAPEFRRPAYLVHAEDETREDWFDTALDGLRYVASLENED

Sequences:

>Translated_285_residues
MNIDLARTFLEIVDTGNFNKAAERLSVTQSTVSMRIRALEEELGRPLFVRSKSGTQLTAAGMQFRRYATTMVRVWEQARQ
ELALPAGFRTVLNVGGQFSLWDRLLVQWIPWMRTAMPDVALKAEVGGSDSLMRQLIEGMLDLVVMYSPLSRPGLHIEKLL
EERLVLVSTRRRAVAEWDEDYVLVDWGPEFRAAHSQAFPDLKTPAVQVGLGALGLQHVLAYGGTGYFPMRVVRSYLSAGR
LFEVTGAPEFRRPAYLVHAEDETREDWFDTALDGLRYVASLENED
>Mature_285_residues
MNIDLARTFLEIVDTGNFNKAAERLSVTQSTVSMRIRALEEELGRPLFVRSKSGTQLTAAGMQFRRYATTMVRVWEQARQ
ELALPAGFRTVLNVGGQFSLWDRLLVQWIPWMRTAMPDVALKAEVGGSDSLMRQLIEGMLDLVVMYSPLSRPGLHIEKLL
EERLVLVSTRRRAVAEWDEDYVLVDWGPEFRAAHSQAFPDLKTPAVQVGLGALGLQHVLAYGGTGYFPMRVVRSYLSAGR
LFEVTGAPEFRRPAYLVHAEDETREDWFDTALDGLRYVASLENED

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=260, Percent_Identity=30, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788297, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=161, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32195; Mature: 32195

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDLARTFLEIVDTGNFNKAAERLSVTQSTVSMRIRALEEELGRPLFVRSKSGTQLTAA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHH
GMQFRRYATTMVRVWEQARQELALPAGFRTVLNVGGQFSLWDRLLVQWIPWMRTAMPDVA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCE
LKAEVGGSDSLMRQLIEGMLDLVVMYSPLSRPGLHIEKLLEERLVLVSTRRRAVAEWDED
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
YVLVDWGPEFRAAHSQAFPDLKTPAVQVGLGALGLQHVLAYGGTGYFPMRVVRSYLSAGR
EEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
LFEVTGAPEFRRPAYLVHAEDETREDWFDTALDGLRYVASLENED
EEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIDLARTFLEIVDTGNFNKAAERLSVTQSTVSMRIRALEEELGRPLFVRSKSGTQLTAA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHH
GMQFRRYATTMVRVWEQARQELALPAGFRTVLNVGGQFSLWDRLLVQWIPWMRTAMPDVA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCE
LKAEVGGSDSLMRQLIEGMLDLVVMYSPLSRPGLHIEKLLEERLVLVSTRRRAVAEWDED
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
YVLVDWGPEFRAAHSQAFPDLKTPAVQVGLGALGLQHVLAYGGTGYFPMRVVRSYLSAGR
EEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
LFEVTGAPEFRRPAYLVHAEDETREDWFDTALDGLRYVASLENED
EEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA