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The map label for this gene is gpt [H]

Identifier: 83313407

GI number: 83313407

Start: 4714203

End: 4714658

Strand: Reverse

Name: gpt [H]

Synonym: amb4308

Alternate gene names: 83313407

Gene position: 4714658-4714203 (Counterclockwise)

Preceding gene: 83313411

Following gene: 83313406

Centisome position: 94.92

GC content: 67.11

Gene sequence:

>456_bases
ATGACCCTCGATCCCGCCTTTTCTCATGCCTGTTCCCTGTCGTGGGAAGAGATCCATTCGGTGTCGCGCCGGCTGGCCCG
CAAGCTCAGGGACAAGGGGCCGTTCACCGGAATCATCGCCGTGGCCCGCGGCGGGCTGGTCCCCGCCGCCATCCTGGCCA
CCGAGTTGGGAATTCGGCAGGTGGATACCGTGTGCATCGCCGGCTATGATGAAAGCACGCGCCATGACCTGGAAATCCTC
AAGCGGGTTCCGGGCGACGGCACCGGCTGGCTGGTGGTGGACGATCTGGTGGATACCGGGCGCACCGCCCAGGCCATCCG
CGACATGCTGCCGGGCGGCCATTACGCCACCCTCTACGCCAAGCCCTCGGGCCGGCCCCTGGTCCACACCCATGTGGAGG
ACGTGGGTCAGAAAACCTGGCTGGTCTTCCCCTGGGAGGCTCCCGAGCGGGCCTGA

Upstream 100 bases:

>100_bases
AGCATCGGGCGGCTGTTCCTATCGGTGGCTGGGCGATTGTTGCGAAATTGCCGCCCGCCGTCCAGAGTGGCGATACCGCT
CATTATGCAACCGGACCGCC

Downstream 100 bases:

>100_bases
GCGGCCGGACGTGAGGCAACCTATGGAAATCGCCCGGGCGCGTAACCATGTATGAAAAATGGCTGTTACGACTAACTCAT
TAATACCAAAGCCCTAACTG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTLDPAFSHACSLSWEEIHSVSRRLARKLRDKGPFTGIIAVARGGLVPAAILATELGIRQVDTVCIAGYDESTRHDLEIL
KRVPGDGTGWLVVDDLVDTGRTAQAIRDMLPGGHYATLYAKPSGRPLVHTHVEDVGQKTWLVFPWEAPERA

Sequences:

>Translated_151_residues
MTLDPAFSHACSLSWEEIHSVSRRLARKLRDKGPFTGIIAVARGGLVPAAILATELGIRQVDTVCIAGYDESTRHDLEIL
KRVPGDGTGWLVVDDLVDTGRTAQAIRDMLPGGHYATLYAKPSGRPLVHTHVEDVGQKTWLVFPWEAPERA
>Mature_150_residues
TLDPAFSHACSLSWEEIHSVSRRLARKLRDKGPFTGIIAVARGGLVPAAILATELGIRQVDTVCIAGYDESTRHDLEILK
RVPGDGTGWLVVDDLVDTGRTAQAIRDMLPGGHYATLYAKPSGRPLVHTHVEDVGQKTWLVFPWEAPERA

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=140, Percent_Identity=52.1428571428571, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 16536; Mature: 16405

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDPAFSHACSLSWEEIHSVSRRLARKLRDKGPFTGIIAVARGGLVPAAILATELGIRQ
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCHHHHHHHHHCHHH
VDTVCIAGYDESTRHDLEILKRVPGDGTGWLVVDDLVDTGRTAQAIRDMLPGGHYATLYA
HCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEE
KPSGRPLVHTHVEDVGQKTWLVFPWEAPERA
CCCCCCEEEHHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TLDPAFSHACSLSWEEIHSVSRRLARKLRDKGPFTGIIAVARGGLVPAAILATELGIRQ
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCHHHHHHHHHCHHH
VDTVCIAGYDESTRHDLEILKRVPGDGTGWLVVDDLVDTGRTAQAIRDMLPGGHYATLYA
HCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEE
KPSGRPLVHTHVEDVGQKTWLVFPWEAPERA
CCCCCCEEEHHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA