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The map label for this gene is atpH

Identifier: 83313241

GI number: 83313241

Start: 4548258

End: 4548812

Strand: Reverse

Name: atpH

Synonym: amb4142

Alternate gene names: 83313241

Gene position: 4548812-4548258 (Counterclockwise)

Preceding gene: 83313243

Following gene: 83313240

Centisome position: 91.58

GC content: 63.42

Gene sequence:

>555_bases
GTGCCTTCCGAAACTATTGGCGTGATCGCCGACCGCTATGCCACCGCTCTCTTCGAGTTGGCCGATTCTTCCGGCTCGCT
CGACCAGGTTGCCGGTGATCTCAAGACGCTCCAGGCCATGCTGCGCGAAAGCGCGGACCTGCGCCGCGTCGTCGACAGCC
CCGTGCTGAGCCGCAACGACCAGGGCAAGGCGATCTCCGCCGTTGCCAAGGCCGCCGGCTTTTCCGAGCTGACGAACAAA
TTTCTTGGTCTGGCGGCTCAAAACCGCCGGCTGCACACCCTTTCGGGGGTGATTGCATCCTATCTTGGCCGGTTGGCGGC
CCGTCGCGGGGAAAAGTCCGCGACGGTGGCTTCCGCCGTGGCTCTCTCGCCGGCCCAGCAAGACGCCCTTACCACCGCCC
TTAAGGCAGCCTTCGGCGGCAATGTCGCCGTCGACGTCAAGGTTGATCCCAGCTTGCTGGGCGGCCTGGTGGTTCAGGTC
GGTTCCCGCATGGTTGACAGCTCGCTGAAGACGAAGCTGCAGCATCTCAAGCTCGCTATGAAAGGGGTTGGATAA

Upstream 100 bases:

>100_bases
CGACGCGCCGACAGGGGGGCTAATCCTGCAGGCGCCAGAATTATGTTGCCTTTCAATAGGTTACGGCTGCCGGTTCGACC
CTATCCAAGGACTTGCCCAG

Downstream 100 bases:

>100_bases
TGGAAATCCGCGCCGCGGAAATCTCCGCAATCCTCAAGCAACAGATCGCCACCTTCGGGACCGAGGCGGAAGTTGCCGAG
GTCGGTCAGGTGCTGTCTGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MPSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRNDQGKAISAVAKAAGFSELTNK
FLGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAVALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQV
GSRMVDSSLKTKLQHLKLAMKGVG

Sequences:

>Translated_184_residues
MPSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRNDQGKAISAVAKAAGFSELTNK
FLGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAVALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQV
GSRMVDSSLKTKLQHLKLAMKGVG
>Mature_183_residues
PSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRNDQGKAISAVAKAAGFSELTNKF
LGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAVALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQVG
SRMVDSSLKTKLQHLKLAMKGVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=184, Percent_Identity=34.7826086956522, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71984710, Length=181, Percent_Identity=35.3591160220994, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71984717, Length=181, Percent_Identity=35.3591160220994, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320504, Length=170, Percent_Identity=30, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647054, Length=175, Percent_Identity=38.2857142857143, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647056, Length=103, Percent_Identity=40.7766990291262, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_MAGSA (Q2VZM9)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423505.1
- ProteinModelPortal:   Q2VZM9
- SMR:   Q2VZM9
- STRING:   Q2VZM9
- GeneID:   3803336
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4142
- NMPDR:   fig|342108.5.peg.3722
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   SIGDKYV
- PhylomeDB:   Q2VZM9
- ProtClustDB:   PRK05758
- BioCyc:   MMAG342108:AMB4142-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19088; Mature: 18957

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRND
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCC
QGKAISAVAKAAGFSELTNKFLGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAV
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQVGSRMVDSSLKTKLQHLKLAM
HHCCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVG
HCCC
>Mature Secondary Structure 
PSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRND
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCC
QGKAISAVAKAAGFSELTNKFLGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAV
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQVGSRMVDSSLKTKLQHLKLAM
HHCCHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA