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The map label for this gene is atpA

Identifier: 83313240

GI number: 83313240

Start: 4546729

End: 4548258

Strand: Reverse

Name: atpA

Synonym: amb4141

Alternate gene names: 83313240

Gene position: 4548258-4546729 (Counterclockwise)

Preceding gene: 83313241

Following gene: 83313239

Centisome position: 91.57

GC content: 64.38

Gene sequence:

>1530_bases
ATGGAAATCCGCGCCGCGGAAATCTCCGCAATCCTCAAGCAACAGATCGCCACCTTCGGGACCGAGGCGGAAGTTGCCGA
GGTCGGTCAGGTGCTGTCTGTCGGTGACGGCATCGCCCGCGTGCACGGCCTCGACAAGGTCCAGGCCGGCGAGATGGTCG
AATTCCCGGGTGGCATCAAGGGTATGGCGCTGAACCTCGAGACCGACAATGTCGGTGTCGTGATCTTCGGCGACGACCGC
AACATCAAGGAAGGCGACGTCGTCAAGCGGACCGGCTCCATCGTGGACGTTCCGGTCGGCAAGGGCCTGCTGGGCCGCGT
CGTCGACGCTCTCGGCAATCCCATCGACGGCAAGGGCCCCATCGAGGCTGCTTCGCGCCAGCGCGTGGACGTCAAGGCCC
CGGGCATCATTCCGCGTAAGTCGGTGCACGAGCCCATGTCCACCGGCATCAAGGCCGTGGACGCCCTGATCCCCATCGGC
CGCGGTCAGCGCGAGCTGGTCATCGGCGATCGCCAGACCGGCAAGACCGCCATCCTGGTCGACACCATCATCAACCAGAA
GCGCTGGCATGACGCCAACGACGAGAAGGCGAAGCTGTTCTGCATCTACGTCGCCGTCGGTCAGAAGCGCTCCACCGTCG
CCCAGATCGTCAAGACCCTGACCGATTACGGCGCCATGGACTACACCATCGTGGTGGCCGCGACCGCGTCGGAGCCCGCT
CCGCTGCAGTTCATCGCCCCCTACGCCGGCTGCACCATGGGCGAGTATTTTCGCGACAACGGCATGCATGCCCTGATCAT
CTATGATGATCTGTCCAAGCAGGCCGTCGCCTACCGTCAGATGTCGCTGCTGCTGCGCCGCCCGCCGGGCCGCGAAGCCT
ATCCCGGCGACGTGTTCTACCTGCACTCGCGCCTGCTCGAGCGCGCCGCCAAGATGGGCGACGCCGCCGGCGCCGGCTCG
CTGACCGCTCTGCCGGTCATCGAGACCCAGGCCAACGACGTGTCGGCCTACATCCCCACCAACGTGATCTCGATCACCGA
CGGCCAGATCTTCCTGGAAACCGAACTGTTCTATAAGGGCATCCGCCCCGCCGTGAACGTCGGTCTGTCGGTGTCGCGCG
TCGGCTCCGCCGCCCAGATCAAGGCGATGAAGCAGGTTGCGGGCTCGATCAAGCTGGAACTGGCCCAGTATCGTGAAATG
GCTGCCTTCGCGCAGTTCGCTTCCGACCTGGATCCGGCCACCCAGAAGCTGCTGGCCCGTGGCGCGCGTCTGACCGAGCT
GCTGAAGCAGCCGCAGTTCTCGCCCATGGCGACGGAAGAGGAAGTCATTTCCATCTACGCCGGCGTGAAGGGCTATCTGG
ACAAGATCGACGTGCGCCAGGTCGGCCGCTTCGAGTCGTCCCTGCTGTCGGAAATCAAGTCGAAGGCGCCGGAAATTCTG
ACCGCCATCGCCACCGAGAAGCAGATCAGCGCCCAGACCGAAGAGAAGCTCAAGGCGTTCCTCGACGCGTTCTCCAAGAC
CTTCGCTTAA

Upstream 100 bases:

>100_bases
TGCTGGGCGGCCTGGTGGTTCAGGTCGGTTCCCGCATGGTTGACAGCTCGCTGAAGACGAAGCTGCAGCATCTCAAGCTC
GCTATGAAAGGGGTTGGATA

Downstream 100 bases:

>100_bases
CCGTCCCGTGGGAGTTTAGGTTATGGCGAGTCTCAAGGACCTGCGGATGAAGATCGTGAGCGTCAAATCGACGCGCAAGA
TCACGTCCGCCATGAAGATG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MEIRAAEISAILKQQIATFGTEAEVAEVGQVLSVGDGIARVHGLDKVQAGEMVEFPGGIKGMALNLETDNVGVVIFGDDR
NIKEGDVVKRTGSIVDVPVGKGLLGRVVDALGNPIDGKGPIEAASRQRVDVKAPGIIPRKSVHEPMSTGIKAVDALIPIG
RGQRELVIGDRQTGKTAILVDTIINQKRWHDANDEKAKLFCIYVAVGQKRSTVAQIVKTLTDYGAMDYTIVVAATASEPA
PLQFIAPYAGCTMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMGDAAGAGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETELFYKGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKLELAQYREM
AAFAQFASDLDPATQKLLARGARLTELLKQPQFSPMATEEEVISIYAGVKGYLDKIDVRQVGRFESSLLSEIKSKAPEIL
TAIATEKQISAQTEEKLKAFLDAFSKTFA

Sequences:

>Translated_509_residues
MEIRAAEISAILKQQIATFGTEAEVAEVGQVLSVGDGIARVHGLDKVQAGEMVEFPGGIKGMALNLETDNVGVVIFGDDR
NIKEGDVVKRTGSIVDVPVGKGLLGRVVDALGNPIDGKGPIEAASRQRVDVKAPGIIPRKSVHEPMSTGIKAVDALIPIG
RGQRELVIGDRQTGKTAILVDTIINQKRWHDANDEKAKLFCIYVAVGQKRSTVAQIVKTLTDYGAMDYTIVVAATASEPA
PLQFIAPYAGCTMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMGDAAGAGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETELFYKGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKLELAQYREM
AAFAQFASDLDPATQKLLARGARLTELLKQPQFSPMATEEEVISIYAGVKGYLDKIDVRQVGRFESSLLSEIKSKAPEIL
TAIATEKQISAQTEEKLKAFLDAFSKTFA
>Mature_509_residues
MEIRAAEISAILKQQIATFGTEAEVAEVGQVLSVGDGIARVHGLDKVQAGEMVEFPGGIKGMALNLETDNVGVVIFGDDR
NIKEGDVVKRTGSIVDVPVGKGLLGRVVDALGNPIDGKGPIEAASRQRVDVKAPGIIPRKSVHEPMSTGIKAVDALIPIG
RGQRELVIGDRQTGKTAILVDTIINQKRWHDANDEKAKLFCIYVAVGQKRSTVAQIVKTLTDYGAMDYTIVVAATASEPA
PLQFIAPYAGCTMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMGDAAGAGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETELFYKGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKLELAQYREM
AAFAQFASDLDPATQKLLARGARLTELLKQPQFSPMATEEEVISIYAGVKGYLDKIDVRQVGRFESSLLSEIKSKAPEIL
TAIATEKQISAQTEEKLKAFLDAFSKTFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=503, Percent_Identity=74.155069582505, Blast_Score=770, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=503, Percent_Identity=74.155069582505, Blast_Score=770, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=296, Percent_Identity=29.3918918918919, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI19913426, Length=355, Percent_Identity=27.887323943662, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI32189394, Length=320, Percent_Identity=25, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=27.0161290322581, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1790172, Length=518, Percent_Identity=56.3706563706564, Blast_Score=583, Evalue=1e-167,
Organism=Escherichia coli, GI1790170, Length=366, Percent_Identity=25.4098360655738, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788251, Length=344, Percent_Identity=27.0348837209302, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=74.9502982107356, Blast_Score=773, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=74.9502982107356, Blast_Score=771, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=69.3836978131213, Blast_Score=698, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=294, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=335, Percent_Identity=26.5671641791045, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=297, Percent_Identity=26.2626262626263, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=57.8947368421053, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=74, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565854, Length=260, Percent_Identity=25.7692307692308, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=70.1195219123506, Blast_Score=742, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=332, Percent_Identity=29.2168674698795, Blast_Score=123, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6322581, Length=404, Percent_Identity=24.7524752475248, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=72.8712871287129, Blast_Score=755, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=304, Percent_Identity=27.3026315789474, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646341, Length=304, Percent_Identity=27.3026315789474, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136796, Length=304, Percent_Identity=27.3026315789474, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24638766, Length=428, Percent_Identity=24.2990654205607, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574560, Length=379, Percent_Identity=24.2744063324538, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24583992, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_MAGSA (Q2VZN0)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423504.1
- ProteinModelPortal:   Q2VZN0
- SMR:   Q2VZN0
- STRING:   Q2VZN0
- GeneID:   3803335
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4141
- NMPDR:   fig|342108.5.peg.3721
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- PhylomeDB:   Q2VZN0
- ProtClustDB:   PRK09281
- BioCyc:   MMAG342108:AMB4141-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54850; Mature: 54850

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAAEISAILKQQIATFGTEAEVAEVGQVLSVGDGIARVHGLDKVQAGEMVEFPGGIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLETDNVGVVIFGDDRNIKEGDVVKRTGSIVDVPVGKGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IEAASRQRVDVKAPGIIPRKSVHEPMSTGIKAVDALIPIGRGQRELVIGDRQTGKTAILV
CCHHCCCCEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTIINQKRWHDANDEKAKLFCIYVAVGQKRSTVAQIVKTLTDYGAMDYTIVVAATASEPA
HHHHCHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
PLQFIAPYAGCTMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CEEEECCCCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMGDAAGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETELFYKG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEHHHHHHC
IRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLAR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GARLTELLKQPQFSPMATEEEVISIYAGVKGYLDKIDVRQVGRFESSLLSEIKSKAPEIL
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIATEKQISAQTEEKLKAFLDAFSKTFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIRAAEISAILKQQIATFGTEAEVAEVGQVLSVGDGIARVHGLDKVQAGEMVEFPGGIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLETDNVGVVIFGDDRNIKEGDVVKRTGSIVDVPVGKGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IEAASRQRVDVKAPGIIPRKSVHEPMSTGIKAVDALIPIGRGQRELVIGDRQTGKTAILV
CCHHCCCCEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTIINQKRWHDANDEKAKLFCIYVAVGQKRSTVAQIVKTLTDYGAMDYTIVVAATASEPA
HHHHCHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
PLQFIAPYAGCTMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CEEEECCCCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMGDAAGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETELFYKG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEHHHHHHC
IRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLAR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GARLTELLKQPQFSPMATEEEVISIYAGVKGYLDKIDVRQVGRFESSLLSEIKSKAPEIL
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIATEKQISAQTEEKLKAFLDAFSKTFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA