Click here to switch to the map view.

The map label for this gene is yciL [C]

Identifier: 83313225

GI number: 83313225

Start: 4530276

End: 4531322

Strand: Reverse

Name: yciL [C]

Synonym: amb4126

Alternate gene names: 83313225

Gene position: 4531322-4530276 (Counterclockwise)

Preceding gene: 83313226

Following gene: 83313224

Centisome position: 91.23

GC content: 68.39

Gene sequence:

>1047_bases
ATGAGCAAGACCGACCGCCCGGCGTCCGAGGGACAAACTTCGAGCGAGGCGAAGCCGAAGCGCGGCGCCACTGAGGCGCC
CGGAGCGCAGCGGAGGAGCCAAGGGAGCGAGGGCGACCGCCCGGTGTCTGAGGGGCAAACAAAAAGCGAAGGCGAGCGCA
TCGCCAAGCGGCTGGCCCGTGCGGGCTTGTGCTCGCGGCGCGAGGCCGAACGCTGGATCGAGGACGGCCGCGTCACCGTC
AACGGCCATCGCCTGAGTTCTCCCGCCTGCGTGGTCGGGCCGGGCGACATCGTCATCGTCGACGGCATTCCCCTGTCCGA
GCCGGAAAAGACCCGGCTGTGGCGTTACCACAAGCCGGCCGGTCTGGTCACCACCCACAAGGACCCCGAGGGGCGACCGA
CGGTGTTCGACCATCTGCCCGAGGGTATGCCCCGGGTGATCTCGGTGGGACGGCTCGACCTCAATTCCGAAGGCCTGCTG
CTGCTGACCAATGACGGCGAGTTGGCCCGCAAGCTGGAGCTGCCTTCCAATGCCTGGCTGCGGCGCTATCGGGTGCGCGT
CCACGGCGAGGTGTCGGAAGACGCCCTGGCCCGGCTGGAGAACGGCATCACCATCGACGGCATGGCCTATGGTCCCATCA
GCGCCACCCTGGACCGCCGCCAGGGCGCCAATGCCTGGCTGAGCGTTTCCTTGCGCGAGGGCAAGAACCGCGAAATCCGC
CGGGTGATGGAATATCTGGGCTGGCCGGTCTCGCGCCTGATCCGCGTCTCCTATGGCCCGTTCCAACTGGGCACCCTGGA
AGAGGGCGCCGCCGACGAGGTGGCGGGCAAGGTGCTGCGCGAGCAGATGGGCGAGGGCAAGGCGGTCCTCAAGCCCAAGG
CCGAGACCAAGTCGGCGGGCGAGCGCGAAAAGGAACAGCGCGTCGCCGCCAAGGCCCGCAAGCAGAAGCTGGCCGAGGAC
AAGCGCGCCGCGAGCGCCAAAAAAGACAAGCCCTACGAGGCCCGGCAAGCGGGCAAGCCCGATGCGCATCGTCGCCGGTC
TTCATAA

Upstream 100 bases:

>100_bases
CAGCGGGACGGACGTTCTGCATCGGGGTGCAATGGCACCCCGAATATGACATCAGCCCGGCGGATTCGGCCCTGCTGCGC
GCCTTTGTAGGAGCATGCCG

Downstream 100 bases:

>100_bases
GGGCCGCCGCCTGGAGGCCCCTTCGGGCCGCGACACCCGCCCCACCGCCGATCGGGTGCGCCAGGCGCTGTTCGACATCC
TGATGCATTCCGATCTGGTG

Product: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSKTDRPASEGQTSSEAKPKRGATEAPGAQRRSQGSEGDRPVSEGQTKSEGERIAKRLARAGLCSRREAERWIEDGRVTV
NGHRLSSPACVVGPGDIVIVDGIPLSEPEKTRLWRYHKPAGLVTTHKDPEGRPTVFDHLPEGMPRVISVGRLDLNSEGLL
LLTNDGELARKLELPSNAWLRRYRVRVHGEVSEDALARLENGITIDGMAYGPISATLDRRQGANAWLSVSLREGKNREIR
RVMEYLGWPVSRLIRVSYGPFQLGTLEEGAADEVAGKVLREQMGEGKAVLKPKAETKSAGEREKEQRVAAKARKQKLAED
KRAASAKKDKPYEARQAGKPDAHRRRSS

Sequences:

>Translated_348_residues
MSKTDRPASEGQTSSEAKPKRGATEAPGAQRRSQGSEGDRPVSEGQTKSEGERIAKRLARAGLCSRREAERWIEDGRVTV
NGHRLSSPACVVGPGDIVIVDGIPLSEPEKTRLWRYHKPAGLVTTHKDPEGRPTVFDHLPEGMPRVISVGRLDLNSEGLL
LLTNDGELARKLELPSNAWLRRYRVRVHGEVSEDALARLENGITIDGMAYGPISATLDRRQGANAWLSVSLREGKNREIR
RVMEYLGWPVSRLIRVSYGPFQLGTLEEGAADEVAGKVLREQMGEGKAVLKPKAETKSAGEREKEQRVAAKARKQKLAED
KRAASAKKDKPYEARQAGKPDAHRRRSS
>Mature_347_residues
SKTDRPASEGQTSSEAKPKRGATEAPGAQRRSQGSEGDRPVSEGQTKSEGERIAKRLARAGLCSRREAERWIEDGRVTVN
GHRLSSPACVVGPGDIVIVDGIPLSEPEKTRLWRYHKPAGLVTTHKDPEGRPTVFDHLPEGMPRVISVGRLDLNSEGLLL
LTNDGELARKLELPSNAWLRRYRVRVHGEVSEDALARLENGITIDGMAYGPISATLDRRQGANAWLSVSLREGKNREIRR
VMEYLGWPVSRLIRVSYGPFQLGTLEEGAADEVAGKVLREQMGEGKAVLKPKAETKSAGEREKEQRVAAKARKQKLAEDK
RAASAKKDKPYEARQAGKPDAHRRRSS

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=218, Percent_Identity=45.8715596330275, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1790453, Length=229, Percent_Identity=34.061135371179, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=34.2391304347826, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788510, Length=212, Percent_Identity=28.7735849056604, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 38369; Mature: 38238

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTDRPASEGQTSSEAKPKRGATEAPGAQRRSQGSEGDRPVSEGQTKSEGERIAKRLAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AGLCSRREAERWIEDGRVTVNGHRLSSPACVVGPGDIVIVDGIPLSEPEKTRLWRYHKPA
HCCHHHHHHHHHHHCCCEEEECCEECCCEEEECCCCEEEECCCCCCCCCHHHCEEEECCC
GLVTTHKDPEGRPTVFDHLPEGMPRVISVGRLDLNSEGLLLLTNDGELARKLELPSNAWL
CCEEECCCCCCCCHHHHHCCCCCHHHHHHCEEEECCCCEEEEECCCHHHHEECCCCHHHH
RRYRVRVHGEVSEDALARLENGITIDGMAYGPISATLDRRQGANAWLSVSLREGKNREIR
HHHHEEECCCCCHHHHHHHHCCCEECCEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHH
RVMEYLGWPVSRLIRVSYGPFQLGTLEEGAADEVAGKVLREQMGEGKAVLKPKAETKSAG
HHHHHHCCCHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHCCC
EREKEQRVAAKARKQKLAEDKRAASAKKDKPYEARQAGKPDAHRRRSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
SKTDRPASEGQTSSEAKPKRGATEAPGAQRRSQGSEGDRPVSEGQTKSEGERIAKRLAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AGLCSRREAERWIEDGRVTVNGHRLSSPACVVGPGDIVIVDGIPLSEPEKTRLWRYHKPA
HCCHHHHHHHHHHHCCCEEEECCEECCCEEEECCCCEEEECCCCCCCCCHHHCEEEECCC
GLVTTHKDPEGRPTVFDHLPEGMPRVISVGRLDLNSEGLLLLTNDGELARKLELPSNAWL
CCEEECCCCCCCCHHHHHCCCCCHHHHHHCEEEECCCCEEEEECCCHHHHEECCCCHHHH
RRYRVRVHGEVSEDALARLENGITIDGMAYGPISATLDRRQGANAWLSVSLREGKNREIR
HHHHEEECCCCCHHHHHHHHCCCEECCEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHH
RVMEYLGWPVSRLIRVSYGPFQLGTLEEGAADEVAGKVLREQMGEGKAVLKPKAETKSAG
HHHHHHCCCHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHCCC
EREKEQRVAAKARKQKLAEDKRAASAKKDKPYEARQAGKPDAHRRRSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA