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The map label for this gene is gpsA

Identifier: 83313105

GI number: 83313105

Start: 4413664

End: 4414491

Strand: Reverse

Name: gpsA

Synonym: amb4006

Alternate gene names: 83313105

Gene position: 4414491-4413664 (Counterclockwise)

Preceding gene: 83313106

Following gene: 83313104

Centisome position: 88.87

GC content: 71.62

Gene sequence:

>828_bases
ATGAAAAAAGTCGGTGTGATCGGCGGAGGGGCATGGGGAACGGCATTGGCGCTGACCGCCCGGCGGGCGGGGCGCGACGT
GGTGCTGTGGGCCCGCGAGCCCCAGGTGGTGGACGACATCAATGTCCGCCACGTCAACTCCGACTTCCTGCCCGGAATCG
ATCTCGATCCCGCCTTGCGCGCCACCGTCGATCTGGCCGATGCGGCCGATGCCGACGCGGTGCTGCTGGTGTCGCCCGCC
CAGCACCTGCGCGCCGCCGCCCGCGCCCTGGCGCCGCACTGGCGGGCCGGTGTTCCCGCCGTCATCTGTTCCAAGGGCAT
CGAGCTGTCCACCTGCGCCCTGATGCAGGATGCAATCGCGGCCGAACTGCCCCAGGCGCCCATCGCCGTGTTGTCCGGCC
CCACCTTCGCCATCGAGGTGGCGCGGGGCCTGCCCACCGCCATCACCCTGGCCTGCGCCGCGCCCGAACTGGGCCGCAAG
CTGGTGGAGGCACTGGGCACCGCCAGCTTCCGCCCCTATCTGTCCGACGATCTGGTGGGGGCTCAGATCGGGGGCGCCGT
CAAGAACGTGCTGGCCATCGCCTGCGGCATCGTCGAGGGGCGCGGCCTGGGCGACAATGCCCGCGCAGCCCTGATCACCC
GCGGGCTGGCCGAGATGACCCGCCTGGCCATGGCCAAGGGCGGGCGGCCCGAGACCCTGATGGGCCTGTCGGGTCTGGGC
GACCTGATCCTCACCGCCTCGTCCACCCAGTCGCGCAACTATTCCTGGGCTTCGCCCTGGGCGAGGGCCGCGCCCTGGCC
GACATCCTGGGCGAGCGCCATTCGGTGA

Upstream 100 bases:

>100_bases
AAGGCGCCGCCGCTCTGCGACGGAACCCACAAGACGCTGTGATCGCTTGCCCGCGCTCCGCCATCGGGGTAAACCGGGGG
ACGGCAATGGCGGGGGCTTC

Downstream 100 bases:

>100_bases
CCGAAGGCGTCTACAGCGCCGGCGCCGTGGTCGACATGGCCGGGCGCACCGGGGTCGAGATGCCCATCTCGGCGGCGGTG
ATGCGGTGATCAATGGTGGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKKVGVIGGGAWGTALALTARRAGRDVVLWAREPQVVDDINVRHVNSDFLPGIDLDPALRATVDLADAADADAVLLVSPA
QHLRAAARALAPHWRAGVPAVICSKGIELSTCALMQDAIAAELPQAPIAVLSGPTFAIEVARGLPTAITLACAAPELGRK
LVEALGTASFRPYLSDDLVGAQIGGAVKNVLAIACGIVEGRGLGDNARAALITRGLAEMTRLAMAKGGRPETLMGLSGLG
DLILTASSTQSRNYSWASPWARAAPWPTSWASAIR

Sequences:

>Translated_275_residues
MKKVGVIGGGAWGTALALTARRAGRDVVLWAREPQVVDDINVRHVNSDFLPGIDLDPALRATVDLADAADADAVLLVSPA
QHLRAAARALAPHWRAGVPAVICSKGIELSTCALMQDAIAAELPQAPIAVLSGPTFAIEVARGLPTAITLACAAPELGRK
LVEALGTASFRPYLSDDLVGAQIGGAVKNVLAIACGIVEGRGLGDNARAALITRGLAEMTRLAMAKGGRPETLMGLSGLG
DLILTASSTQSRNYSWASPWARAAPWPTSWASAIR
>Mature_275_residues
MKKVGVIGGGAWGTALALTARRAGRDVVLWAREPQVVDDINVRHVNSDFLPGIDLDPALRATVDLADAADADAVLLVSPA
QHLRAAARALAPHWRAGVPAVICSKGIELSTCALMQDAIAAELPQAPIAVLSGPTFAIEVARGLPTAITLACAAPELGRK
LVEALGTASFRPYLSDDLVGAQIGGAVKNVLAIACGIVEGRGLGDNARAALITRGLAEMTRLAMAKGGRPETLMGLSGLG
DLILTASSTQSRNYSWASPWARAAPWPTSWASAIR

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=279, Percent_Identity=32.9749103942652, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI24307999, Length=278, Percent_Identity=30.5755395683453, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790037, Length=254, Percent_Identity=45.6692913385827, Blast_Score=197, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI32564399, Length=276, Percent_Identity=30.0724637681159, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32564403, Length=285, Percent_Identity=29.4736842105263, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193210136, Length=285, Percent_Identity=29.4736842105263, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17507425, Length=276, Percent_Identity=28.2608695652174, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320181, Length=276, Percent_Identity=34.0579710144928, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=292, Percent_Identity=33.5616438356164, Blast_Score=112, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136204, Length=273, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17136200, Length=273, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17136202, Length=273, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI22026922, Length=275, Percent_Identity=25.4545454545455, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281362270, Length=236, Percent_Identity=28.8135593220339, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45551945, Length=236, Percent_Identity=28.8135593220339, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648969, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_MAGSA (Q2W015)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423369.1
- HSSP:   P21695
- ProteinModelPortal:   Q2W015
- SMR:   Q2W015
- STRING:   Q2W015
- GeneID:   3804923
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4006
- NMPDR:   fig|342108.5.peg.3600
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   ALVACCK
- BioCyc:   MMAG342108:AMB4006-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 28446; Mature: 28446

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 188-188 BINDING 105-105 BINDING 105-105 BINDING 137-137 BINDING 252-252

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGVIGGGAWGTALALTARRAGRDVVLWAREPQVVDDINVRHVNSDFLPGIDLDPALR
CCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHH
ATVDLADAADADAVLLVSPAQHLRAAARALAPHWRAGVPAVICSKGIELSTCALMQDAIA
HEEECCCCCCCCEEEEECCHHHHHHHHHHHCCHHHCCCCHHHHHCCCCHHHHHHHHHHHH
AELPQAPIAVLSGPTFAIEVARGLPTAITLACAAPELGRKLVEALGTASFRPYLSDDLVG
HHCCCCCEEEECCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHH
AQIGGAVKNVLAIACGIVEGRGLGDNARAALITRGLAEMTRLAMAKGGRPETLMGLSGLG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
DLILTASSTQSRNYSWASPWARAAPWPTSWASAIR
CEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MKKVGVIGGGAWGTALALTARRAGRDVVLWAREPQVVDDINVRHVNSDFLPGIDLDPALR
CCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHH
ATVDLADAADADAVLLVSPAQHLRAAARALAPHWRAGVPAVICSKGIELSTCALMQDAIA
HEEECCCCCCCCEEEEECCHHHHHHHHHHHCCHHHCCCCHHHHHCCCCHHHHHHHHHHHH
AELPQAPIAVLSGPTFAIEVARGLPTAITLACAAPELGRKLVEALGTASFRPYLSDDLVG
HHCCCCCEEEECCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHH
AQIGGAVKNVLAIACGIVEGRGLGDNARAALITRGLAEMTRLAMAKGGRPETLMGLSGLG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
DLILTASSTQSRNYSWASPWARAAPWPTSWASAIR
CEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA