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The map label for this gene is cph2 [H]

Identifier: 83312993

GI number: 83312993

Start: 4303434

End: 4305110

Strand: Reverse

Name: cph2 [H]

Synonym: amb3894

Alternate gene names: 83312993

Gene position: 4305110-4303434 (Counterclockwise)

Preceding gene: 83312995

Following gene: 83312992

Centisome position: 86.67

GC content: 69.29

Gene sequence:

>1677_bases
ATGAGCACATCAGGGGAAAAATCCAGGGCGAAGTCCCCGCAAGGAGGGCGGCCCATGCTGGTCTTGGGGGCCGAGGGGTT
GAACGCCTTTCCCGGCCCCGCATTGCTGCTCGACCATGATGGTTCCATCCTGGCCGCCAATCACCGGGCCGAGCCGCTGG
TCCAGGCGGTGGCGCAGGACCGGCTCGGCTGCCTTTCGGCCCTGCTGGCCCAGCCCGGTGCCACCTCGGTGGAGAGTCTG
CCGCTGGTCAGCGGCGGCACCCTGATTCTCGATCTGGTGTCCATTCCCACCGAAGGCGGCCAGACCGTGCTGTTCGGCCG
CGACGTGACCCTGGAGCGCAACCTGCGGGCCGCCCTGGTGGAATCGCGCCAGCGCTACAAGGACCTGGTGGAGATTTCCA
GCGATTTCGCCTGGGAGACCGGCGCCGACGGCCATTTCGTCTTCGTCAGCCCCAAGGGCGCCCTGGGTTTCGCCGCCGAC
GAACTGGTGGGGCGCCGTCCCGCCGACTTCGTGCTGCAGGAGGAAAGCACCCACGGCCCCGGCCCCTTCGACGCGGTGTC
GCCGGTGGAGGACATCGAGGTATGGATGCGCCAGTCCGACGGCAATCCGCTCTGCCTTCTGGCCTCGTCCACGCCCATCC
GGGGCGATGGCGGCGAGTGGCGCGGCGCCCGCGGGGTCTGCCGCGACGTGACCCAGGAGCGGCTGCGCGACGCGGCGCTG
TCGCGCGCCAACAACCGCGAACGCCTGCTCAGCTACATCGTGCGCACCATCCGCGACGAGGTGGACCCGGCCGACATGCT
GAAGGCGGCGGCCGAGGCCACCGCCCGGGCGCTGGGCGCCACCGGCTGCCAGATCTTCCGCATCCAGTCCGACGATTCCG
ATTTCGCGCCATCGGCCGAATACGGCACCTTCGGCGATGCCCGTCCGGTGCTCGACACCTTCGAGGCCAGCGACCATTAC
GACGCCGACCTGGGCGACTGGCGGGTGCTGGCCAGCGTCTGCCGCTATCGCCACTCCATCAACGGCGCCGTGCTGCTGTG
GCGGGAGATGAGCCGCGCCGCCTGGAGCGACGACGACCGCCTGCTCATCGACGACGTGGCCAACCAGGTGGGTCTGGCTT
CCGAGCAGATCACCAACCACGAGCGCATGGTCAAGCTGTCGCGCACCGACGGCCTGACCGGGCTGTTCAACCGCCGCGCC
TTCTTCGAGGAGATCGCCCGGCGCTTCCACCGCCTGAAGCGCGAGGGCAAGCCGGCGGCCCTGATCTATGTGGATCTCGA
CAACTTCAAGGCGGTCAACGACGTCCACGGCCACCAGACCGGCGACGAGGCCCTGCTGGCGGTGCGCGACCTGCTGTTGC
AGCACACGCGGCCCATCGATCTGGTGGCGCGCCTGGGCGGCGACGAATTCGCCATCTGGCTGGAAGCCGCCGAGGAGCAC
ATCGCCGTCAAGCGCTGCCAGGACGTGCTGGAGGCGGCCAAGGATCTGGATCGCTTCTCCGGCTCGCCGGAAAAGCCATT
GGGATGTTCCCTCGGCGTGGCGGTGCATGGCGGCAGCTACAACGAGGCGCTGGAAGACCTGATCGCCCGCGCCGACAAGG
CCATGTACGAGGTCAAGCGCAGCGGCAAGGGTGCTTGGCGCATCGCGCCGGCCGCCGAGGACGGAGGCGCCGCGTGA

Upstream 100 bases:

>100_bases
GCCCCGGCCTCCGTGGCAAGCACCCCCCTTTAGGGGATCGTTAAGCGCCTATGCCTATGGTAGGAACTAAGGACGACAGG
ATGGGCCGGATCCGCACTCA

Downstream 100 bases:

>100_bases
CCGGCTTTCTCAAGCGCTTGTTCGGCGCCGGGCGCAAGGGACCGCTGGACTACGAGCAGGCCAAGGAACTGGCCGCCCAT
CCCGATTCCAAGGTGCGCGC

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSTSGEKSRAKSPQGGRPMLVLGAEGLNAFPGPALLLDHDGSILAANHRAEPLVQAVAQDRLGCLSALLAQPGATSVESL
PLVSGGTLILDLVSIPTEGGQTVLFGRDVTLERNLRAALVESRQRYKDLVEISSDFAWETGADGHFVFVSPKGALGFAAD
ELVGRRPADFVLQEESTHGPGPFDAVSPVEDIEVWMRQSDGNPLCLLASSTPIRGDGGEWRGARGVCRDVTQERLRDAAL
SRANNRERLLSYIVRTIRDEVDPADMLKAAAEATARALGATGCQIFRIQSDDSDFAPSAEYGTFGDARPVLDTFEASDHY
DADLGDWRVLASVCRYRHSINGAVLLWREMSRAAWSDDDRLLIDDVANQVGLASEQITNHERMVKLSRTDGLTGLFNRRA
FFEEIARRFHRLKREGKPAALIYVDLDNFKAVNDVHGHQTGDEALLAVRDLLLQHTRPIDLVARLGGDEFAIWLEAAEEH
IAVKRCQDVLEAAKDLDRFSGSPEKPLGCSLGVAVHGGSYNEALEDLIARADKAMYEVKRSGKGAWRIAPAAEDGGAA

Sequences:

>Translated_558_residues
MSTSGEKSRAKSPQGGRPMLVLGAEGLNAFPGPALLLDHDGSILAANHRAEPLVQAVAQDRLGCLSALLAQPGATSVESL
PLVSGGTLILDLVSIPTEGGQTVLFGRDVTLERNLRAALVESRQRYKDLVEISSDFAWETGADGHFVFVSPKGALGFAAD
ELVGRRPADFVLQEESTHGPGPFDAVSPVEDIEVWMRQSDGNPLCLLASSTPIRGDGGEWRGARGVCRDVTQERLRDAAL
SRANNRERLLSYIVRTIRDEVDPADMLKAAAEATARALGATGCQIFRIQSDDSDFAPSAEYGTFGDARPVLDTFEASDHY
DADLGDWRVLASVCRYRHSINGAVLLWREMSRAAWSDDDRLLIDDVANQVGLASEQITNHERMVKLSRTDGLTGLFNRRA
FFEEIARRFHRLKREGKPAALIYVDLDNFKAVNDVHGHQTGDEALLAVRDLLLQHTRPIDLVARLGGDEFAIWLEAAEEH
IAVKRCQDVLEAAKDLDRFSGSPEKPLGCSLGVAVHGGSYNEALEDLIARADKAMYEVKRSGKGAWRIAPAAEDGGAA
>Mature_557_residues
STSGEKSRAKSPQGGRPMLVLGAEGLNAFPGPALLLDHDGSILAANHRAEPLVQAVAQDRLGCLSALLAQPGATSVESLP
LVSGGTLILDLVSIPTEGGQTVLFGRDVTLERNLRAALVESRQRYKDLVEISSDFAWETGADGHFVFVSPKGALGFAADE
LVGRRPADFVLQEESTHGPGPFDAVSPVEDIEVWMRQSDGNPLCLLASSTPIRGDGGEWRGARGVCRDVTQERLRDAALS
RANNRERLLSYIVRTIRDEVDPADMLKAAAEATARALGATGCQIFRIQSDDSDFAPSAEYGTFGDARPVLDTFEASDHYD
ADLGDWRVLASVCRYRHSINGAVLLWREMSRAAWSDDDRLLIDDVANQVGLASEQITNHERMVKLSRTDGLTGLFNRRAF
FEEIARRFHRLKREGKPAALIYVDLDNFKAVNDVHGHQTGDEALLAVRDLLLQHTRPIDLVARLGGDEFAIWLEAAEEHI
AVKRCQDVLEAAKDLDRFSGSPEKPLGCSLGVAVHGGSYNEALEDLIARADKAMYEVKRSGKGAWRIAPAAEDGGAA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=32.620320855615, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=30.5732484076433, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=32.1637426900585, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=31.638418079096, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=35.9756097560976, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=90, Percent_Identity=40, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.7560975609756, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=32.5153374233129, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 60567; Mature: 60435

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSGEKSRAKSPQGGRPMLVLGAEGLNAFPGPALLLDHDGSILAANHRAEPLVQAVAQD
CCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHH
RLGCLSALLAQPGATSVESLPLVSGGTLILDLVSIPTEGGQTVLFGRDVTLERNLRAALV
HHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
ESRQRYKDLVEISSDFAWETGADGHFVFVSPKGALGFAADELVGRRPADFVLQEESTHGP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCHHEEECCCCCCC
GPFDAVSPVEDIEVWMRQSDGNPLCLLASSTPIRGDGGEWRGARGVCRDVTQERLRDAAL
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SRANNRERLLSYIVRTIRDEVDPADMLKAAAEATARALGATGCQIFRIQSDDSDFAPSAE
HHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
YGTFGDARPVLDTFEASDHYDADLGDWRVLASVCRYRHSINGAVLLWREMSRAAWSDDDR
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCC
LLIDDVANQVGLASEQITNHERMVKLSRTDGLTGLFNRRAFFEEIARRFHRLKREGKPAA
CHHHHHHHHHCCCHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LIYVDLDNFKAVNDVHGHQTGDEALLAVRDLLLQHTRPIDLVARLGGDEFAIWLEAAEEH
EEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHH
IAVKRCQDVLEAAKDLDRFSGSPEKPLGCSLGVAVHGGSYNEALEDLIARADKAMYEVKR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SGKGAWRIAPAAEDGGAA
CCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
STSGEKSRAKSPQGGRPMLVLGAEGLNAFPGPALLLDHDGSILAANHRAEPLVQAVAQD
CCCCCCHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHH
RLGCLSALLAQPGATSVESLPLVSGGTLILDLVSIPTEGGQTVLFGRDVTLERNLRAALV
HHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
ESRQRYKDLVEISSDFAWETGADGHFVFVSPKGALGFAADELVGRRPADFVLQEESTHGP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCHHEEECCCCCCC
GPFDAVSPVEDIEVWMRQSDGNPLCLLASSTPIRGDGGEWRGARGVCRDVTQERLRDAAL
CCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SRANNRERLLSYIVRTIRDEVDPADMLKAAAEATARALGATGCQIFRIQSDDSDFAPSAE
HHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
YGTFGDARPVLDTFEASDHYDADLGDWRVLASVCRYRHSINGAVLLWREMSRAAWSDDDR
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCC
LLIDDVANQVGLASEQITNHERMVKLSRTDGLTGLFNRRAFFEEIARRFHRLKREGKPAA
CHHHHHHHHHCCCHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LIYVDLDNFKAVNDVHGHQTGDEALLAVRDLLLQHTRPIDLVARLGGDEFAIWLEAAEEH
EEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHH
IAVKRCQDVLEAAKDLDRFSGSPEKPLGCSLGVAVHGGSYNEALEDLIARADKAMYEVKR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SGKGAWRIAPAAEDGGAA
CCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]