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The map label for this gene is moaE [H]

Identifier: 83312894

GI number: 83312894

Start: 4192797

End: 4193273

Strand: Reverse

Name: moaE [H]

Synonym: amb3795

Alternate gene names: 83312894

Gene position: 4193273-4192797 (Counterclockwise)

Preceding gene: 83312895

Following gene: 83312893

Centisome position: 84.42

GC content: 67.3

Gene sequence:

>477_bases
ATGGCCGTTCGGGTGCAGCGCGAGGATTTCGATCCCGGCGCCGAGCTGGAGCGTTTTTCATCGGGCAAGACCAGCGTGGG
CGGCATCTGCCTGTTCGTCGGGCTGGTGCGCGATTATGCCGGCCATGATCCGGCCAGCGGCGCCGCCGTCAACGCCATGA
CCCTGGAACATTATCCCGGCATGACCGAGCGCCAGTTGGAGGCCATCGAAGCCGAGGCCCGCCAGCGCTGGCCCCTGGAT
GATACCCTGGTCATTCATCGCTTCGGCCGGCTGGAGCCGGGCGAGCGCATCGTGCTGGTGGCGGCGTCGTCGGCCCACCG
CGATGCCGCCTTCGAGGCCTGCCGTTTCCTCATGGACTGGCTGAAGACCAAGGCGCCGTTCTGGAAGGTGGAACATACCC
CGGAGGGTGATGCCTGGGTCGAGGCCAAGCAATCCGACGACGCGGCGGCGTCGCGCTGGGACAAGGGGACTCCCTGA

Upstream 100 bases:

>100_bases
ACGGTCCGCGTCGCCGTGAACCAGGATTACGGCAACCTGGACACTCCGGTGAAGGCCGGCGACGAGGTGGCGTTCTTCCC
GCCCGTCACAGGAGGCTGAC

Downstream 100 bases:

>100_bases
TTTCCCAGGGGCAAAAGGCTGCGCCATCGGAGCGGTCGGGTCAAGCTCAATCGTCTTTTACCTTTTGTTAACCTCTTGAC
TTGTGGTAGGCTTGGGGCCT

Product: molybdopterin converting factor, large subunit

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAVRVQREDFDPGAELERFSSGKTSVGGICLFVGLVRDYAGHDPASGAAVNAMTLEHYPGMTERQLEAIEAEARQRWPLD
DTLVIHRFGRLEPGERIVLVAASSAHRDAAFEACRFLMDWLKTKAPFWKVEHTPEGDAWVEAKQSDDAAASRWDKGTP

Sequences:

>Translated_158_residues
MAVRVQREDFDPGAELERFSSGKTSVGGICLFVGLVRDYAGHDPASGAAVNAMTLEHYPGMTERQLEAIEAEARQRWPLD
DTLVIHRFGRLEPGERIVLVAASSAHRDAAFEACRFLMDWLKTKAPFWKVEHTPEGDAWVEAKQSDDAAASRWDKGTP
>Mature_157_residues
AVRVQREDFDPGAELERFSSGKTSVGGICLFVGLVRDYAGHDPASGAAVNAMTLEHYPGMTERQLEAIEAEARQRWPLDD
TLVIHRFGRLEPGERIVLVAASSAHRDAAFEACRFLMDWLKTKAPFWKVEHTPEGDAWVEAKQSDDAAASRWDKGTP

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=37.1681415929204, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787003, Length=127, Percent_Identity=58.2677165354331, Blast_Score=151, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356259, Length=123, Percent_Identity=34.9593495934959, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17555; Mature: 17424

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVQREDFDPGAELERFSSGKTSVGGICLFVGLVRDYAGHDPASGAAVNAMTLEHYPG
CCEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
MTERQLEAIEAEARQRWPLDDTLVIHRFGRLEPGERIVLVAASSAHRDAAFEACRFLMDW
CCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LKTKAPFWKVEHTPEGDAWVEAKQSDDAAASRWDKGTP
HHCCCCCEEEECCCCCCCEEECCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
AVRVQREDFDPGAELERFSSGKTSVGGICLFVGLVRDYAGHDPASGAAVNAMTLEHYPG
CEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
MTERQLEAIEAEARQRWPLDDTLVIHRFGRLEPGERIVLVAASSAHRDAAFEACRFLMDW
CCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LKTKAPFWKVEHTPEGDAWVEAKQSDDAAASRWDKGTP
HHCCCCCEEEECCCCCCCEEECCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]