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The map label for this gene is yheS [H]

Identifier: 83312658

GI number: 83312658

Start: 3912663

End: 3914543

Strand: Reverse

Name: yheS [H]

Synonym: amb3559

Alternate gene names: 83312658

Gene position: 3914543-3912663 (Counterclockwise)

Preceding gene: 83312659

Following gene: 83312657

Centisome position: 78.81

GC content: 67.94

Gene sequence:

>1881_bases
ATGCTGCATATCAACGACCTCACTTTCCGCTATGGCGGCCGGGCCATCTTCGAGCAGGCGACCGTTCACATCCCGGCCGG
GGCGCGTGTCGGCCTGGTCGGGCGCAATGGCACCGGCAAGACCACCCTGTTCAAGCTGATCCTGGGCGAACTGCACCCCG
ATGGCGGCGAGATCAACCTGCGCCCCCGCGCCCGGCTGGGCCGGCTGGCCCAGGAGGCGCCCGAGGGCGACATCTCGTTG
ATCGATTGCGTGCTGGCCGCCGACACCGAGCGCACCGCCCTGTTCGAGGAGGCGGAGACCTCCACCGACGGCCACCGCAT
CGCCGAGATCCACGAGCGGCTGATGGCCATCGACGCCCATTCTGCACCGTCGCGGGCCGCCGCCATCCTGTCGGGGCTGG
GCTTCGACGCCGAGGCGCAATTGCAGCCGGTCTCGGACTTCTCGGGCGGCTGGCGCATGCGCGTCGCCCTGGCGGCGTCG
CTGTTCACCGTTCCCGACCTGCTGCTGCTGGACGAGCCCACCAATCACCTGGATCTGGAAGCCACCTTGTGGCTGCAAAG
CCACCTGGCCGCCTATCCCGGCACCCTGGTGGTGATCAGCCACGACCGCGAGATGCTCAACGAGGTGGCCAACCGCATCA
TCCACCTGGAGAACGGCAAGCTGAACGCCTATGGCGGCAATTACGACCGCTTCGAGGCGACCCGCCGGGCCCGCATGGAA
TTGCAGGCCAAGGCCTTCACCAAGCAGCAGGAACAGCGCAAGAAGATCCAGTCCTTCATCGACCGCTTCAAGGCCAAGGC
CACCAAGGCCGCCCAGGCCCAAAGCCGGGTCAAGATGCTCGAGCGCATGGAGATGGTGGTCCCCGTGGTCGAGGACCGCG
CCATGTCCTTCGACTTCCCCGATCCCGAACCGCTCAGCCCGCCCATCATCGCCATCGACCACGGCGTGGCCGGGTATGGC
GACAAGGTGGTGCTGAAGGGGCTCGACATCCGCATCGACATGGACGACCGCATCGCCCTTCTGGGCGCCAACGGCAACGG
CAAGTCGACCCTGGCCAAGATCTTTTCCGGACGCCTCGACCTGCTGAGCGGCCAGTTCCGCAAGCCGCCCAAGCTGAAGA
TCGGCTATTTCGCCCAGCATCAGACCGAGGAATTGCGGCTGGACGAGACGCCCTACGAGCATATGGCCCTGCTGATGAAG
GGCCTGCCCGAGGCCAAGGTCCGCGCCCAGCTTGGCCGCTTCGGCTTCGAGCAGGACCGCGCCAACGTCAAGGTCGCCAG
CCTGTCGGGCGGCGAGAAGTCGCGCCTGCTCTTCGCCCTGATGAGCCGCGAGGCGCCTCACCTGATGATCCTGGACGAGC
CCACCAATCACCTGGACATCGACGCCCGCGAAGCCCTGGTGGCGGCGCTCAACGCCTATGACGGCGCGGTGATCCTGATC
AGCCACGACCCCCATCTGATCGAGCTGGCCGCCGACAGCCTGTGGCTGGTGGGCGATGGCGCGGTCAAGCCCTTCGATGG
CGATCTGGCCGCCTATCGCAAGCTGTTGCTCGACCGGGCCCGCGAGGACCGCCGGGGGGCCAAGCCGGAACGGGTCGGCG
ACGCCGCCCAGCGCAAGGCCGATCGCAAGGCGGCGGCCGGCGCCCGCGCCCAGTTGGCGCCGCTGCGCAAGGCGGCTCTG
GCGGCGGAAAAGGCCCTGGAGGATTTGGTCAAGGCCCAAAAGGTCCTGAGCGGGCAATTGGCCGACCCCAAGCTCTACCA
GGGGCCGCCCGCCAAGGTCACCGAACTGCGGCGCCAGGAAGCCGATCTCGCCCGCCGGGTGGAAGAGGCGGAACTGGCCT
GGCTGGCCGCCCAGGAGGAACTGGAAGCGGCGCAGGCATAG

Upstream 100 bases:

>100_bases
ATCCGGGGACGGCGGGTTATAACCTCATTGAATGAGGAGAGCAACGGTCTCTACAAGCCCGCCTTTGCCGAGAGGGCGCC
GCCGTGCTATTGACGCGGCC

Downstream 100 bases:

>100_bases
GCATTATGCCGCTTCCGGCCACCGGCCTTTCGGTATAAGCTGACCATCACCTTTTCCACCAGGGAATCGCCTCGGTGCCC
ACCGAGTCTTTTGCAACCAA

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MLHINDLTFRYGGRAIFEQATVHIPAGARVGLVGRNGTGKTTLFKLILGELHPDGGEINLRPRARLGRLAQEAPEGDISL
IDCVLAADTERTALFEEAETSTDGHRIAEIHERLMAIDAHSAPSRAAAILSGLGFDAEAQLQPVSDFSGGWRMRVALAAS
LFTVPDLLLLDEPTNHLDLEATLWLQSHLAAYPGTLVVISHDREMLNEVANRIIHLENGKLNAYGGNYDRFEATRRARME
LQAKAFTKQQEQRKKIQSFIDRFKAKATKAAQAQSRVKMLERMEMVVPVVEDRAMSFDFPDPEPLSPPIIAIDHGVAGYG
DKVVLKGLDIRIDMDDRIALLGANGNGKSTLAKIFSGRLDLLSGQFRKPPKLKIGYFAQHQTEELRLDETPYEHMALLMK
GLPEAKVRAQLGRFGFEQDRANVKVASLSGGEKSRLLFALMSREAPHLMILDEPTNHLDIDAREALVAALNAYDGAVILI
SHDPHLIELAADSLWLVGDGAVKPFDGDLAAYRKLLLDRAREDRRGAKPERVGDAAQRKADRKAAAGARAQLAPLRKAAL
AAEKALEDLVKAQKVLSGQLADPKLYQGPPAKVTELRRQEADLARRVEEAELAWLAAQEELEAAQA

Sequences:

>Translated_626_residues
MLHINDLTFRYGGRAIFEQATVHIPAGARVGLVGRNGTGKTTLFKLILGELHPDGGEINLRPRARLGRLAQEAPEGDISL
IDCVLAADTERTALFEEAETSTDGHRIAEIHERLMAIDAHSAPSRAAAILSGLGFDAEAQLQPVSDFSGGWRMRVALAAS
LFTVPDLLLLDEPTNHLDLEATLWLQSHLAAYPGTLVVISHDREMLNEVANRIIHLENGKLNAYGGNYDRFEATRRARME
LQAKAFTKQQEQRKKIQSFIDRFKAKATKAAQAQSRVKMLERMEMVVPVVEDRAMSFDFPDPEPLSPPIIAIDHGVAGYG
DKVVLKGLDIRIDMDDRIALLGANGNGKSTLAKIFSGRLDLLSGQFRKPPKLKIGYFAQHQTEELRLDETPYEHMALLMK
GLPEAKVRAQLGRFGFEQDRANVKVASLSGGEKSRLLFALMSREAPHLMILDEPTNHLDIDAREALVAALNAYDGAVILI
SHDPHLIELAADSLWLVGDGAVKPFDGDLAAYRKLLLDRAREDRRGAKPERVGDAAQRKADRKAAAGARAQLAPLRKAAL
AAEKALEDLVKAQKVLSGQLADPKLYQGPPAKVTELRRQEADLARRVEEAELAWLAAQEELEAAQA
>Mature_626_residues
MLHINDLTFRYGGRAIFEQATVHIPAGARVGLVGRNGTGKTTLFKLILGELHPDGGEINLRPRARLGRLAQEAPEGDISL
IDCVLAADTERTALFEEAETSTDGHRIAEIHERLMAIDAHSAPSRAAAILSGLGFDAEAQLQPVSDFSGGWRMRVALAAS
LFTVPDLLLLDEPTNHLDLEATLWLQSHLAAYPGTLVVISHDREMLNEVANRIIHLENGKLNAYGGNYDRFEATRRARME
LQAKAFTKQQEQRKKIQSFIDRFKAKATKAAQAQSRVKMLERMEMVVPVVEDRAMSFDFPDPEPLSPPIIAIDHGVAGYG
DKVVLKGLDIRIDMDDRIALLGANGNGKSTLAKIFSGRLDLLSGQFRKPPKLKIGYFAQHQTEELRLDETPYEHMALLMK
GLPEAKVRAQLGRFGFEQDRANVKVASLSGGEKSRLLFALMSREAPHLMILDEPTNHLDIDAREALVAALNAYDGAVILI
SHDPHLIELAADSLWLVGDGAVKPFDGDLAAYRKLLLDRAREDRRGAKPERVGDAAQRKADRKAAAGARAQLAPLRKAAL
AAEKALEDLVKAQKVLSGQLADPKLYQGPPAKVTELRRQEADLARRVEEAELAWLAAQEELEAAQA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=41.5270018621974, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI27881506, Length=529, Percent_Identity=38.7523629489603, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI10947137, Length=529, Percent_Identity=38.7523629489603, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=39.7769516728625, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=39.7769516728625, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI171184400, Length=240, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1789751, Length=628, Percent_Identity=45.0636942675159, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1787041, Length=525, Percent_Identity=34.8571428571429, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI1787182, Length=517, Percent_Identity=32.495164410058, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI2367384, Length=524, Percent_Identity=30.1526717557252, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI48994943, Length=513, Percent_Identity=25.5360623781676, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789891, Length=238, Percent_Identity=27.7310924369748, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788165, Length=205, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789586, Length=235, Percent_Identity=29.3617021276596, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=249, Percent_Identity=28.1124497991968, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788644, Length=249, Percent_Identity=26.9076305220884, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081834, Length=235, Percent_Identity=28.936170212766, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=525, Percent_Identity=40.1904761904762, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17559834, Length=545, Percent_Identity=36.697247706422, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17555318, Length=539, Percent_Identity=36.9202226345083, Blast_Score=350, Evalue=9e-97,
Organism=Caenorhabditis elegans, GI17565586, Length=224, Percent_Identity=24.5535714285714, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=552, Percent_Identity=37.5, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=35.9168241965974, Blast_Score=339, Evalue=9e-94,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=29.9479166666667, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324314, Length=430, Percent_Identity=26.2790697674419, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323278, Length=423, Percent_Identity=26.9503546099291, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=40.0379506641366, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24642252, Length=542, Percent_Identity=38.0073800738007, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI18859989, Length=542, Percent_Identity=38.0073800738007, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=35.3159851301115, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24659289, Length=232, Percent_Identity=28.8793103448276, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 68786; Mature: 68786

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHINDLTFRYGGRAIFEQATVHIPAGARVGLVGRNGTGKTTLFKLILGELHPDGGEINL
CEEECCEEEECCCEEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
RPRARLGRLAQEAPEGDISLIDCVLAADTERTALFEEAETSTDGHRIAEIHERLMAIDAH
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
SAPSRAAAILSGLGFDAEAQLQPVSDFSGGWRMRVALAASLFTVPDLLLLDEPTNHLDLE
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCCCCE
ATLWLQSHLAAYPGTLVVISHDREMLNEVANRIIHLENGKLNAYGGNYDRFEATRRARME
EHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCEEECCCCCCHHHHHHHHHHHH
LQAKAFTKQQEQRKKIQSFIDRFKAKATKAAQAQSRVKMLERMEMVVPVVEDRAMSFDFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
DPEPLSPPIIAIDHGVAGYGDKVVLKGLDIRIDMDDRIALLGANGNGKSTLAKIFSGRLD
CCCCCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHCCHHH
LLSGQFRKPPKLKIGYFAQHQTEELRLDETPYEHMALLMKGLPEAKVRAQLGRFGFEQDR
HHCCCCCCCCCEEEEEECCCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
ANVKVASLSGGEKSRLLFALMSREAPHLMILDEPTNHLDIDAREALVAALNAYDGAVILI
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
SHDPHLIELAADSLWLVGDGAVKPFDGDLAAYRKLLLDRAREDRRGAKPERVGDAAQRKA
ECCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHH
DRKAAAGARAQLAPLRKAALAAEKALEDLVKAQKVLSGQLADPKLYQGPPAKVTELRRQE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ADLARRVEEAELAWLAAQEELEAAQA
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHINDLTFRYGGRAIFEQATVHIPAGARVGLVGRNGTGKTTLFKLILGELHPDGGEINL
CEEECCEEEECCCEEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
RPRARLGRLAQEAPEGDISLIDCVLAADTERTALFEEAETSTDGHRIAEIHERLMAIDAH
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
SAPSRAAAILSGLGFDAEAQLQPVSDFSGGWRMRVALAASLFTVPDLLLLDEPTNHLDLE
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCCCCCE
ATLWLQSHLAAYPGTLVVISHDREMLNEVANRIIHLENGKLNAYGGNYDRFEATRRARME
EHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCEEECCCCCCHHHHHHHHHHHH
LQAKAFTKQQEQRKKIQSFIDRFKAKATKAAQAQSRVKMLERMEMVVPVVEDRAMSFDFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
DPEPLSPPIIAIDHGVAGYGDKVVLKGLDIRIDMDDRIALLGANGNGKSTLAKIFSGRLD
CCCCCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHCCHHH
LLSGQFRKPPKLKIGYFAQHQTEELRLDETPYEHMALLMKGLPEAKVRAQLGRFGFEQDR
HHCCCCCCCCCEEEEEECCCCCHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
ANVKVASLSGGEKSRLLFALMSREAPHLMILDEPTNHLDIDAREALVAALNAYDGAVILI
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
SHDPHLIELAADSLWLVGDGAVKPFDGDLAAYRKLLLDRAREDRRGAKPERVGDAAQRKA
ECCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHH
DRKAAAGARAQLAPLRKAALAAEKALEDLVKAQKVLSGQLADPKLYQGPPAKVTELRRQE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ADLARRVEEAELAWLAAQEELEAAQA
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]