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The map label for this gene is arpC [H]

Identifier: 83312530

GI number: 83312530

Start: 3757261

End: 3758652

Strand: Reverse

Name: arpC [H]

Synonym: amb3431

Alternate gene names: 83312530

Gene position: 3758652-3757261 (Counterclockwise)

Preceding gene: 83312532

Following gene: 83312529

Centisome position: 75.67

GC content: 70.26

Gene sequence:

>1392_bases
GTGACCAGAAAAGCCCTTTCCGCCCTTGCCCTCGTCGTGCTGTCGGCCTGCTCGGTGGGTGACGAGTATGTGCGCCCCCC
GGCGCCGCCGCCGGCCCAGTGGAAGAACGCGGCCCAGGGCAATGTCTGGCCGGGGAGCGACTGGTGGCGGCAGTTCAATT
CGCCGCGTCTGGACGAATTGATGGCGCGGGCCCGGACCGCCAATTTCGATCTGGCCGCCGCCACGGCGCGGGTGCGTCAG
GCCGATGCCCAACTGGGGGTGGCCGGGGCGTCGCTGTTGCCCTCGCTGTCCGCCTCGGCCGGCGAGACCCGGGCGCGGGC
GTCGCGGGCGGCCAGCACCACCACCACCACCAAGGCGCGGCACACCAGCACCACCAGCGCCACCCTGACCGCCAGCTACG
AGATCGATTTCTGGGGCAAGAACGCCGCGGCGGTCGACGCGGCCCAGGCCGCGGCCGAGGCGTCGCGCTTCGATTTGCAG
ACGGCGGTCCTGACCGCCCAGTCGGGGGTGGCCACCACCTATTTCGAGATCCTGGGCCTGCAGGAACGCATCCGGCTGGT
CAAGGAATCCATCGCCAATTCCGAAGGCATCCTGGCGGTGTTCAGCGATCGCCAGCGGGCGGGCACCGCCACCTCGCTGG
ATGTGGCGCAGCAGGAAAGCGTGCTGGCCACCCAACGGGCGACCCTGGCGCCGCTGGAGCGCCAGATGCGCCAGGACTAC
AACGCCCTGGCCATTCTGACCGGACGCATGCCCGAGGAATTCGCCCTGGTGCCCGAGACCCTGGGCGGCCTGGCCGTGCC
GGTGGTGGGGGCGGGGCTGCCGTCGGAACTGCTGGCCCGGCGGCCCGACGTGCAATCGGCCGAGGCATCCCTGCGCGCCG
CCAACGCCGATATCGCGGCGGCCCGCGCCGCGTGGTTTCCCGCCATCTCGCTGACGGGGCAGGGAGGCTTTCAGAGCCTG
GACCTGCTGAAGATGATGACGGCGCAAAGCCTGCTGTGGTCAGTGGCCTCCACCGCCACCCAAACCATCTTCGACGGTGG
CAAGATCGCCGGGACGGTGGAGCAGAAGCGCGCCCGCTTCGAGGAACTGTCCCAGACCTACCGCAAGGCGGTGGCTTCGG
CCTTCTCCGACGTGGAGAACGCCCTGATCGCCGTGGAGATGGCGGTCGAGGAGGTGGAATCCCAGCGCCGCGCCGAGGCC
ACGGCACGCCGCGCCTTCGAGATCGCCCAGGCCCAGATGGCCGGCGGCATCGTCGACGTCACCACCGTGCTCAACACCCA
AAAGACCCTGTTCTCGGCCCAGGATGCCCTGGCCCAGGCCCGGCTGTCCCAGATGCAGGCCATCGTCGGCCTCTACAAGG
CCTTGGGTGGCGGCTGGCAGGCGGGGAAGTGA

Upstream 100 bases:

>100_bases
ATATTTTGCAGGGCAGACGTGAATGCCTTGTAACCGGGACACGACGCTTCCGTTATCGTAATATCAACAGCGCCGCGCCG
GGCCGCCAGGAGATCCAGAC

Downstream 100 bases:

>100_bases
TCGACTGAGTCGATTTCAAAAACAGCTTTAACTCGTTTCATTCGATCAGTTTGTTTCTGTAGGGTTTCTCCATCGGATCA
CACCAAGGAGATGACCCCAA

Product: Outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTRKALSALALVVLSACSVGDEYVRPPAPPPAQWKNAAQGNVWPGSDWWRQFNSPRLDELMARARTANFDLAAATARVRQ
ADAQLGVAGASLLPSLSASAGETRARASRAASTTTTTKARHTSTTSATLTASYEIDFWGKNAAAVDAAQAAAEASRFDLQ
TAVLTAQSGVATTYFEILGLQERIRLVKESIANSEGILAVFSDRQRAGTATSLDVAQQESVLATQRATLAPLERQMRQDY
NALAILTGRMPEEFALVPETLGGLAVPVVGAGLPSELLARRPDVQSAEASLRAANADIAAARAAWFPAISLTGQGGFQSL
DLLKMMTAQSLLWSVASTATQTIFDGGKIAGTVEQKRARFEELSQTYRKAVASAFSDVENALIAVEMAVEEVESQRRAEA
TARRAFEIAQAQMAGGIVDVTTVLNTQKTLFSAQDALAQARLSQMQAIVGLYKALGGGWQAGK

Sequences:

>Translated_463_residues
MTRKALSALALVVLSACSVGDEYVRPPAPPPAQWKNAAQGNVWPGSDWWRQFNSPRLDELMARARTANFDLAAATARVRQ
ADAQLGVAGASLLPSLSASAGETRARASRAASTTTTTKARHTSTTSATLTASYEIDFWGKNAAAVDAAQAAAEASRFDLQ
TAVLTAQSGVATTYFEILGLQERIRLVKESIANSEGILAVFSDRQRAGTATSLDVAQQESVLATQRATLAPLERQMRQDY
NALAILTGRMPEEFALVPETLGGLAVPVVGAGLPSELLARRPDVQSAEASLRAANADIAAARAAWFPAISLTGQGGFQSL
DLLKMMTAQSLLWSVASTATQTIFDGGKIAGTVEQKRARFEELSQTYRKAVASAFSDVENALIAVEMAVEEVESQRRAEA
TARRAFEIAQAQMAGGIVDVTTVLNTQKTLFSAQDALAQARLSQMQAIVGLYKALGGGWQAGK
>Mature_462_residues
TRKALSALALVVLSACSVGDEYVRPPAPPPAQWKNAAQGNVWPGSDWWRQFNSPRLDELMARARTANFDLAAATARVRQA
DAQLGVAGASLLPSLSASAGETRARASRAASTTTTTKARHTSTTSATLTASYEIDFWGKNAAAVDAAQAAAEASRFDLQT
AVLTAQSGVATTYFEILGLQERIRLVKESIANSEGILAVFSDRQRAGTATSLDVAQQESVLATQRATLAPLERQMRQDYN
ALAILTGRMPEEFALVPETLGGLAVPVVGAGLPSELLARRPDVQSAEASLRAANADIAAARAAWFPAISLTGQGGFQSLD
LLKMMTAQSLLWSVASTATQTIFDGGKIAGTVEQKRARFEELSQTYRKAVASAFSDVENALIAVEMAVEEVESQRRAEAT
ARRAFEIAQAQMAGGIVDVTTVLNTQKTLFSAQDALAQARLSQMQAIVGLYKALGGGWQAGK

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=463, Percent_Identity=28.0777537796976, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI2367348, Length=501, Percent_Identity=25.5489021956088, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49049; Mature: 48918

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKALSALALVVLSACSVGDEYVRPPAPPPAQWKNAAQGNVWPGSDWWRQFNSPRLDEL
CCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCCHHHH
MARARTANFDLAAATARVRQADAQLGVAGASLLPSLSASAGETRARASRAASTTTTTKAR
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
HTSTTSATLTASYEIDFWGKNAAAVDAAQAAAEASRFDLQTAVLTAQSGVATTYFEILGL
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QERIRLVKESIANSEGILAVFSDRQRAGTATSLDVAQQESVLATQRATLAPLERQMRQDY
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NALAILTGRMPEEFALVPETLGGLAVPVVGAGLPSELLARRPDVQSAEASLRAANADIAA
CEEEEEECCCCHHHHHCHHHHCCEEHHHHCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHH
ARAAWFPAISLTGQGGFQSLDLLKMMTAQSLLWSVASTATQTIFDGGKIAGTVEQKRARF
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHH
EELSQTYRKAVASAFSDVENALIAVEMAVEEVESQRRAEATARRAFEIAQAQMAGGIVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
TTVLNTQKTLFSAQDALAQARLSQMQAIVGLYKALGGGWQAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TRKALSALALVVLSACSVGDEYVRPPAPPPAQWKNAAQGNVWPGSDWWRQFNSPRLDEL
CHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCCHHHH
MARARTANFDLAAATARVRQADAQLGVAGASLLPSLSASAGETRARASRAASTTTTTKAR
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
HTSTTSATLTASYEIDFWGKNAAAVDAAQAAAEASRFDLQTAVLTAQSGVATTYFEILGL
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QERIRLVKESIANSEGILAVFSDRQRAGTATSLDVAQQESVLATQRATLAPLERQMRQDY
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NALAILTGRMPEEFALVPETLGGLAVPVVGAGLPSELLARRPDVQSAEASLRAANADIAA
CEEEEEECCCCHHHHHCHHHHCCEEHHHHCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHH
ARAAWFPAISLTGQGGFQSLDLLKMMTAQSLLWSVASTATQTIFDGGKIAGTVEQKRARF
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHH
EELSQTYRKAVASAFSDVENALIAVEMAVEEVESQRRAEATARRAFEIAQAQMAGGIVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
TTVLNTQKTLFSAQDALAQARLSQMQAIVGLYKALGGGWQAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]