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The map label for this gene is arsC [H]

Identifier: 83312439

GI number: 83312439

Start: 3631187

End: 3631630

Strand: Reverse

Name: arsC [H]

Synonym: amb3340

Alternate gene names: 83312439

Gene position: 3631630-3631187 (Counterclockwise)

Preceding gene: 83312440

Following gene: 83312438

Centisome position: 73.11

GC content: 65.32

Gene sequence:

>444_bases
ATGGGGGACCTGCCCTCCGCCGTACTGTTCTGCTGCACCATGAACGCGGTGCGGTCGCCCATGGCGGAAGGCATCATGAA
GCGCATCCACGGCAAGCGCGTCTATGTCTATTCCGTCGGCGTGCGCCGGGGCGAGCCCGATCCCTTCGTGGTCCAGGTGA
TGGACGAGATCGGCATCGACGTCTCCAAGCACAAGCCGCGCCTGTTCGAGGAACTGGAGGACGACAGCTTCGACGTGGTG
GTCTCGCTGTCGCCCGAGGCCCAGCACAAGGCGGTGGACCTGACCCGGCACAACGCCTGCGAGGTGGAGTTCTGGCCCAC
CTTCGATCCCACCCTGATCGAAGGCAGCCGCGAGGTTCGCCTCGATGCCTACCGCGCGGTGCGCGATGAATTGGAACGCC
ACATCCGCAAGCGGTTCCCGCCTTCGGGCATGGCGCGGGAATAA

Upstream 100 bases:

>100_bases
CTGCGCGAACGCCTGGGGGGGAAGATCGACGTGGATTTCGATACGGCGCGGCGCCTGTTCACCCTGATCTGCGTCCTCCA
TATCAGGGGGTAGGGGGGAG

Downstream 100 bases:

>100_bases
TAACCCCTTCCATGCTCGAAAAGGCTTGACCAAAACCCTGCCTGCGCTCACTTATCTTCGCGCGCGCAAAACCCAGTTCG
GAGGCCAAATGGCGAAAGAG

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MGDLPSAVLFCCTMNAVRSPMAEGIMKRIHGKRVYVYSVGVRRGEPDPFVVQVMDEIGIDVSKHKPRLFEELEDDSFDVV
VSLSPEAQHKAVDLTRHNACEVEFWPTFDPTLIEGSREVRLDAYRAVRDELERHIRKRFPPSGMARE

Sequences:

>Translated_147_residues
MGDLPSAVLFCCTMNAVRSPMAEGIMKRIHGKRVYVYSVGVRRGEPDPFVVQVMDEIGIDVSKHKPRLFEELEDDSFDVV
VSLSPEAQHKAVDLTRHNACEVEFWPTFDPTLIEGSREVRLDAYRAVRDELERHIRKRFPPSGMARE
>Mature_146_residues
GDLPSAVLFCCTMNAVRSPMAEGIMKRIHGKRVYVYSVGVRRGEPDPFVVQVMDEIGIDVSKHKPRLFEELEDDSFDVVV
SLSPEAQHKAVDLTRHNACEVEFWPTFDPTLIEGSREVRLDAYRAVRDELERHIRKRFPPSGMARE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16814; Mature: 16683

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDLPSAVLFCCTMNAVRSPMAEGIMKRIHGKRVYVYSVGVRRGEPDPFVVQVMDEIGID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
VSKHKPRLFEELEDDSFDVVVSLSPEAQHKAVDLTRHNACEVEFWPTFDPTLIEGSREVR
CCCCCCHHHHHCCCCCEEEEEEECCCCCHHEECCCCCCCEEEEEECCCCCCEECCCCHHH
LDAYRAVRDELERHIRKRFPPSGMARE
HHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GDLPSAVLFCCTMNAVRSPMAEGIMKRIHGKRVYVYSVGVRRGEPDPFVVQVMDEIGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
VSKHKPRLFEELEDDSFDVVVSLSPEAQHKAVDLTRHNACEVEFWPTFDPTLIEGSREVR
CCCCCCHHHHHCCCCCEEEEEEECCCCCHHEECCCCCCCEEEEEECCCCCCEECCCCHHH
LDAYRAVRDELERHIRKRFPPSGMARE
HHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA