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The map label for this gene is slyD [H]

Identifier: 83312354

GI number: 83312354

Start: 3517931

End: 3519016

Strand: Reverse

Name: slyD [H]

Synonym: amb3255

Alternate gene names: 83312354

Gene position: 3519016-3517931 (Counterclockwise)

Preceding gene: 83312357

Following gene: 83312353

Centisome position: 70.85

GC content: 65.38

Gene sequence:

>1086_bases
ATGAAGATCGAAGCCAACACCGCCGTCACCTTACGCTTGAGGGTTGCCACCCCGGACGGCGACGTCGTCGACCCCGGGGC
CGAGCCCCTAAGTTATCTGCACGGAGGCCATGGCGGGCTCTTTCCCAAGCTGGAGGCGGCTCTCGATGGCCTGGGCGCCG
GCGACAGCGTTCAAGTGACATTGGCGCCCGAGGACGGGTTCGGACCCTTTGACACCGCGCTGACCATGACGGTATCGCTG
GACCGCCTCGAGGCGCCTCCCAAGGTCGGCGACGTGCTGGAGCGGGATGTTAACGGCGTCACCCTGCAATACCGCGTGAC
CGCCGTCGGTGACCGGAACGTCGGGCTGGACGGCAACCATCCACTGGCCGGCCAGACATTGGTTTTTTCCGCGACGGTGA
CGGATGTCCGGACGGCCACGCCCGAGGAGGTCGCCGGCGAAGTCGCCACCCTGAATCGGGCGGCGATGGACCTGGCGTCG
AGGGGGCGGGCTGTTGCCCGGGCTAAGGCCGAAGCGGAGGCCGAGGCCGAAGCCGCTATTTTGGCCGAAGCCGAGGCGGC
GGGCCTGGTTGAGAGCTCCTATTTGCCCCAACTGGGTACCCGTATCCGTTTCGTCTTCCGTTCGCAGACCCACAAGCTCT
GCTGGCTGGCGCCCCTGTTCCTTTTGCCGGCGATCGCCACTTGGCTCGGGCTGCGCGGCTGGGAGGTTGCCTGTGGCATT
ACCGTCGCCCTGTGGCTGGCCTGGTGCTTCCTGGCTCCGGGCATTATCGGCAGGGCGATCAAACGCTGGGGTTATCAGTT
CCTGTTCTTCGACTTCTCGCCCAACCTCACCCCCTCCAGGCTGGAGCGCGGTATCGTCAACGGCAGCGCCGCCTTGTCGG
TAATAGCGGTCCTGGCTTTCACCGTGGTCGCGCTGTTTCGCATGCGGCATCTGTCCGATCTGCTGGAGATCATCGGCCTG
GATCTGGCCATTCTCTTTGCGGTCGGTGTCCCCTTGATCATCCTGCTGCCGTTCCTGGTGATAATTCTGACGGCCTTCCG
GGTCAGGCCGGTCATCGACCGGGCTCCGTCCGCTCCGAGGGGCTGA

Upstream 100 bases:

>100_bases
GGATTTGGCCGGCGGGCCATCCACGGCTTGCCCATCGCGGCCGATTGTGGCAGGTCGATAATCCTGCATTTCACAGCAGG
GGTCTCATCCGGGGCGCACC

Downstream 100 bases:

>100_bases
CCGTCATATGGCCCTTGGAGCCGTGCCGTCAGCCACGTATTGTTGTGACAATTGCGGGGGAGGGGCGCATGGACGCCTGG
GACAGTTTGCTGCTCGTGGT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase 2

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKIEANTAVTLRLRVATPDGDVVDPGAEPLSYLHGGHGGLFPKLEAALDGLGAGDSVQVTLAPEDGFGPFDTALTMTVSL
DRLEAPPKVGDVLERDVNGVTLQYRVTAVGDRNVGLDGNHPLAGQTLVFSATVTDVRTATPEEVAGEVATLNRAAMDLAS
RGRAVARAKAEAEAEAEAAILAEAEAAGLVESSYLPQLGTRIRFVFRSQTHKLCWLAPLFLLPAIATWLGLRGWEVACGI
TVALWLAWCFLAPGIIGRAIKRWGYQFLFFDFSPNLTPSRLERGIVNGSAALSVIAVLAFTVVALFRMRHLSDLLEIIGL
DLAILFAVGVPLIILLPFLVIILTAFRVRPVIDRAPSAPRG

Sequences:

>Translated_361_residues
MKIEANTAVTLRLRVATPDGDVVDPGAEPLSYLHGGHGGLFPKLEAALDGLGAGDSVQVTLAPEDGFGPFDTALTMTVSL
DRLEAPPKVGDVLERDVNGVTLQYRVTAVGDRNVGLDGNHPLAGQTLVFSATVTDVRTATPEEVAGEVATLNRAAMDLAS
RGRAVARAKAEAEAEAEAAILAEAEAAGLVESSYLPQLGTRIRFVFRSQTHKLCWLAPLFLLPAIATWLGLRGWEVACGI
TVALWLAWCFLAPGIIGRAIKRWGYQFLFFDFSPNLTPSRLERGIVNGSAALSVIAVLAFTVVALFRMRHLSDLLEIIGL
DLAILFAVGVPLIILLPFLVIILTAFRVRPVIDRAPSAPRG
>Mature_361_residues
MKIEANTAVTLRLRVATPDGDVVDPGAEPLSYLHGGHGGLFPKLEAALDGLGAGDSVQVTLAPEDGFGPFDTALTMTVSL
DRLEAPPKVGDVLERDVNGVTLQYRVTAVGDRNVGLDGNHPLAGQTLVFSATVTDVRTATPEEVAGEVATLNRAAMDLAS
RGRAVARAKAEAEAEAEAAILAEAEAAGLVESSYLPQLGTRIRFVFRSQTHKLCWLAPLFLLPAIATWLGLRGWEVACGI
TVALWLAWCFLAPGIIGRAIKRWGYQFLFFDFSPNLTPSRLERGIVNGSAALSVIAVLAFTVVALFRMRHLSDLLEIIGL
DLAILFAVGVPLIILLPFLVIILTAFRVRPVIDRAPSAPRG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=153, Percent_Identity=39.2156862745098, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 38504; Mature: 38504

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEANTAVTLRLRVATPDGDVVDPGAEPLSYLHGGHGGLFPKLEAALDGLGAGDSVQVT
CEEECCEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEE
LAPEDGFGPFDTALTMTVSLDRLEAPPKVGDVLERDVNGVTLQYRVTAVGDRNVGLDGNH
ECCCCCCCCCHHHEEEEEEHHHHCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC
PLAGQTLVFSATVTDVRTATPEEVAGEVATLNRAAMDLASRGRAVARAKAEAEAEAEAAI
CCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAEAEAAGLVESSYLPQLGTRIRFVFRSQTHKLCWLAPLFLLPAIATWLGLRGWEVACGI
HHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
TVALWLAWCFLAPGIIGRAIKRWGYQFLFFDFSPNLTPSRLERGIVNGSAALSVIAVLAF
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHH
TVVALFRMRHLSDLLEIIGLDLAILFAVGVPLIILLPFLVIILTAFRVRPVIDRAPSAPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
G
C
>Mature Secondary Structure
MKIEANTAVTLRLRVATPDGDVVDPGAEPLSYLHGGHGGLFPKLEAALDGLGAGDSVQVT
CEEECCEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEE
LAPEDGFGPFDTALTMTVSLDRLEAPPKVGDVLERDVNGVTLQYRVTAVGDRNVGLDGNH
ECCCCCCCCCHHHEEEEEEHHHHCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCC
PLAGQTLVFSATVTDVRTATPEEVAGEVATLNRAAMDLASRGRAVARAKAEAEAEAEAAI
CCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAEAEAAGLVESSYLPQLGTRIRFVFRSQTHKLCWLAPLFLLPAIATWLGLRGWEVACGI
HHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
TVALWLAWCFLAPGIIGRAIKRWGYQFLFFDFSPNLTPSRLERGIVNGSAALSVIAVLAF
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHH
TVVALFRMRHLSDLLEIIGLDLAILFAVGVPLIILLPFLVIILTAFRVRPVIDRAPSAPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]