Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 83312298

GI number: 83312298

Start: 3467321

End: 3468676

Strand: Reverse

Name: glmM

Synonym: amb3199

Alternate gene names: 83312298

Gene position: 3468676-3467321 (Counterclockwise)

Preceding gene: 83312299

Following gene: 83312296

Centisome position: 69.83

GC content: 67.4

Gene sequence:

>1356_bases
ATGACGCGCAAGCTGTTCGGCACCGACGGGATCAGGGGCACCGCCAACACCGACCCCATGACGGCCGAGATGGCCATGAA
ACTGGGCATGGCGGCGGGAAGGCACTTCACCCGCGGCGATCATCGCCACGTGGTGGTGATCGGCAAGGACACCCGTCTGT
CGGGCTATCTGCTGGAGCCGGCTCTGACCGCGGGTTTCATCTCGGTGGGCATGGACGTGGTGCTGCTGGGCCCGTTGCCC
ACGCCGGCGGTGGCCTTGCTGACGCGGTCCATGCGCGCCGATCTCGGCGTGATGATCTCGGCGTCGCACAATCCCTATGA
GGATAACGGCATCAAGCTGTTCGGCCCCGATGGCTTCAAGCTCTCCGACGAGGACGAGCTGACCATCGAGGCCTCCATGT
CCAACGGACTGGAATCCTGCCGGGTGGGCTCGGACCATCTGGGCCGCGCCAAGCGCCTGGACGATGCGGCCGGGCGCTAT
ATCGAATACGCCAAGTACACCTTCCCGCGCGGCCTGCGCCTGGACGGCCTGAAGATCGTGGTCGATTGCGCCAACGGCGC
CGCCTACAAGGTGGCCCCCACCGTGCTGTGGGAACTAGGCGCCGAGGTGATTCCCGTGGCGGTGAATCCCGACGGCTTCA
ACATCAACAAGAATTGCGGTTCGCTGCACACCGAGACCATGCGCGAGCAGGTGGTGGCCCATGGCGCCCATCTGGGCATC
GCGCTCGACGGCGACGCCGACCGGGTGGTGCTGTGCGACGAACTGGGCCACATGATCGACGGCGACCAGTTGATGGCGCT
GATCGGCGATCTGTGGCACCGCTCGGGTCAGCTGAAGGGCGGCGGCATCGTCGCCACGGTGATGTCCAATTTGGGGCTGG
AGCGCTTTCTGGACCAGCGGGGCCTGAAGACCATCCGCACGGCGGTGGGCGACCGCTATGTGCTGGAGCACATGCGCCGC
GACGGCTTCAACGTGGGTGGCGAGCAGTCGGGCCATATCATCCTGTCGGACCATTCCACCACCGGCGACGGTTTGGTGGC
GGGGTTGCAGGTGCTGGCCGCGCTGGTGCAGTCGGGCAAGCCGGCCAGCGAGATGCTGCGCCTGTTCACGCCGCTGCCCC
AGGTGCTGAAGAATGTACGGGTGGCCAAGGGCTCGGTGGCCGAGGTGCTGGCCGCGCCCGCCGTCGAGGCCGCCATCCGC
GATGCCGAAGCCAAGCTGGCCGGGCAGGGCCGTCTGCTGATCCGCAAGTCGGGGACCGAGCCGCTGATCCGGGTGATGGC
CGAAGGCGAGGACGAGGGCCTGGTCGAGGCCTCGGTCGATGCCATCGTCGAGACCATCCGCCGGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
GTCCTGACCCGTAGGGCAGGATGCCCAACCCTTTCTCCTTCCCTTCGCCTTTCCGGCTTGCTATCCAATCCTCCTTTCGG
ACGAAGGGAAGCATAACGGG

Downstream 100 bases:

>100_bases
GGGCGTAAAAAAGGGGGCTTCTGCCCCCTTGCCTTGATCCCGGCTGTTAAGCCGCCGCCGTGGCGGCTTCGGGAGCGAAG
CGCTCCACCACCCGGCTCAT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTRKLFGTDGIRGTANTDPMTAEMAMKLGMAAGRHFTRGDHRHVVVIGKDTRLSGYLLEPALTAGFISVGMDVVLLGPLP
TPAVALLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFKLSDEDELTIEASMSNGLESCRVGSDHLGRAKRLDDAAGRY
IEYAKYTFPRGLRLDGLKIVVDCANGAAYKVAPTVLWELGAEVIPVAVNPDGFNINKNCGSLHTETMREQVVAHGAHLGI
ALDGDADRVVLCDELGHMIDGDQLMALIGDLWHRSGQLKGGGIVATVMSNLGLERFLDQRGLKTIRTAVGDRYVLEHMRR
DGFNVGGEQSGHIILSDHSTTGDGLVAGLQVLAALVQSGKPASEMLRLFTPLPQVLKNVRVAKGSVAEVLAAPAVEAAIR
DAEAKLAGQGRLLIRKSGTEPLIRVMAEGEDEGLVEASVDAIVETIRRAAG

Sequences:

>Translated_451_residues
MTRKLFGTDGIRGTANTDPMTAEMAMKLGMAAGRHFTRGDHRHVVVIGKDTRLSGYLLEPALTAGFISVGMDVVLLGPLP
TPAVALLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFKLSDEDELTIEASMSNGLESCRVGSDHLGRAKRLDDAAGRY
IEYAKYTFPRGLRLDGLKIVVDCANGAAYKVAPTVLWELGAEVIPVAVNPDGFNINKNCGSLHTETMREQVVAHGAHLGI
ALDGDADRVVLCDELGHMIDGDQLMALIGDLWHRSGQLKGGGIVATVMSNLGLERFLDQRGLKTIRTAVGDRYVLEHMRR
DGFNVGGEQSGHIILSDHSTTGDGLVAGLQVLAALVQSGKPASEMLRLFTPLPQVLKNVRVAKGSVAEVLAAPAVEAAIR
DAEAKLAGQGRLLIRKSGTEPLIRVMAEGEDEGLVEASVDAIVETIRRAAG
>Mature_450_residues
TRKLFGTDGIRGTANTDPMTAEMAMKLGMAAGRHFTRGDHRHVVVIGKDTRLSGYLLEPALTAGFISVGMDVVLLGPLPT
PAVALLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFKLSDEDELTIEASMSNGLESCRVGSDHLGRAKRLDDAAGRYI
EYAKYTFPRGLRLDGLKIVVDCANGAAYKVAPTVLWELGAEVIPVAVNPDGFNINKNCGSLHTETMREQVVAHGAHLGIA
LDGDADRVVLCDELGHMIDGDQLMALIGDLWHRSGQLKGGGIVATVMSNLGLERFLDQRGLKTIRTAVGDRYVLEHMRRD
GFNVGGEQSGHIILSDHSTTGDGLVAGLQVLAALVQSGKPASEMLRLFTPLPQVLKNVRVAKGSVAEVLAAPAVEAAIRD
AEAKLAGQGRLLIRKSGTEPLIRVMAEGEDEGLVEASVDAIVETIRRAAG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=51.5695067264574, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788361, Length=459, Percent_Identity=27.2331154684096, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_MAGSA (Q2W2C2)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422562.1
- HSSP:   Q9P4V2
- ProteinModelPortal:   Q2W2C2
- SMR:   Q2W2C2
- STRING:   Q2W2C2
- GeneID:   3805288
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb3199
- NMPDR:   fig|342108.5.peg.2871
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q2W2C2
- ProtClustDB:   PRK14315
- BioCyc:   MMAG342108:AMB3199-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48052; Mature: 47921

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLFGTDGIRGTANTDPMTAEMAMKLGMAAGRHFTRGDHRHVVVIGKDTRLSGYLLEP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECH
ALTAGFISVGMDVVLLGPLPTPAVALLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFK
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCE
LSDEDELTIEASMSNGLESCRVGSDHLGRAKRLDDAAGRYIEYAKYTFPRGLRLDGLKIV
ECCCCCEEEEECHHCCHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEE
VDCANGAAYKVAPTVLWELGAEVIPVAVNPDGFNINKNCGSLHTETMREQVVAHGAHLGI
EECCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ALDGDADRVVLCDELGHMIDGDQLMALIGDLWHRSGQLKGGGIVATVMSNLGLERFLDQR
EECCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
GLKTIRTAVGDRYVLEHMRRDGFNVGGEQSGHIILSDHSTTGDGLVAGLQVLAALVQSGK
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
PASEMLRLFTPLPQVLKNVRVAKGSVAEVLAAPAVEAAIRDAEAKLAGQGRLLIRKSGTE
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
PLIRVMAEGEDEGLVEASVDAIVETIRRAAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRKLFGTDGIRGTANTDPMTAEMAMKLGMAAGRHFTRGDHRHVVVIGKDTRLSGYLLEP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECH
ALTAGFISVGMDVVLLGPLPTPAVALLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFK
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCE
LSDEDELTIEASMSNGLESCRVGSDHLGRAKRLDDAAGRYIEYAKYTFPRGLRLDGLKIV
ECCCCCEEEEECHHCCHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEE
VDCANGAAYKVAPTVLWELGAEVIPVAVNPDGFNINKNCGSLHTETMREQVVAHGAHLGI
EECCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ALDGDADRVVLCDELGHMIDGDQLMALIGDLWHRSGQLKGGGIVATVMSNLGLERFLDQR
EECCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
GLKTIRTAVGDRYVLEHMRRDGFNVGGEQSGHIILSDHSTTGDGLVAGLQVLAALVQSGK
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
PASEMLRLFTPLPQVLKNVRVAKGSVAEVLAAPAVEAAIRDAEAKLAGQGRLLIRKSGTE
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
PLIRVMAEGEDEGLVEASVDAIVETIRRAAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA