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The map label for this gene is degS [H]

Identifier: 83312237

GI number: 83312237

Start: 3383420

End: 3384937

Strand: Reverse

Name: degS [H]

Synonym: amb3138

Alternate gene names: 83312237

Gene position: 3384937-3383420 (Counterclockwise)

Preceding gene: 83312238

Following gene: 83312236

Centisome position: 68.15

GC content: 68.84

Gene sequence:

>1518_bases
TTGACGTTTCTAAATAGGGTGAAGACCTTAAGCGGCCAAGGCGCTATCATCTTCCTTGTAAATCCCGGGGCGCCACAACC
CGGGTGGAGCGTCAAGGGAGAAGCCATGAGCTCGCGGTGGGGCAAGACGATGGCGATGCTGATCGCCATGGGCGGCGCGT
TGCCCGTCCAGGCGGCCTGTTTGGCGCGCCCGTCGTCCACTGCCGAACTGGCCCAATGCTCCACCGCCGCCGCCGCCGGC
GATTCCGTTGCCGCCCGGATGTTGGGCGATGTGATGGGCGATCCCACCCAGCGCCATTACGATCCCGCCACGGCTTTGTC
CTGGTGGGAGCAGGCCGCCGCCGCAGGAGACGGTCTGGCGTTGCGTCGTCTGTTCGATGCCCACTGGTATGGCCGCGGCA
CGCCCAAGGATCTGGCCAAGGCCAGGACCTATCTGGCCAAGGCGGTGGCGGGCGGAGCCCAGTGGGCTCGGCTGGTGCGG
GCCGTCCTGGCGGAAGGGGAGGAGCCCGGCCTCGCCGCCGACCTGTACAACGGCCTGGCGGCCGAGGGCAATTGTCTAGC
CCAGTTGCGCCTCGCCCATGGCCACGACCGGGGCGGCTGGGTCGAGAAGAACCGCTCGCAAGCCCTCTATTGGGCCAATG
TGGCGGGGCTGGCGGGACGAAACGAGCCGCCGCCCGAGGATCACCCCCTGTTCGAGAACCGCTTTCACTATCGCGATTGC
ACCAGCGAGGCCTACTTCCTGCGGCAGGAGCTGGCCCACAATCTGGCGTCGGACCTGCGGGGGCGGGTGGAGGAGTCGGC
GGCGGCGTGGAAGCCCGGTCGGATGCCCGAGCGTCAGGGGCCGGTGGAGGCGCCTCCAGCCATCGGCGTGACGCCGGTCG
GGCTGGGCTCCGGCGCCGCGGCCAAGCTGCCGGACTGGCGGCCGCTTGCCGCGTCGTTGCAGCGGCCGGCGGGCCGGTCG
CGCCTGGGGGCCGAGGACGTGTTCGCCACGGTGGGCCGGTCGGTCTATGTGGTGATCGCCGCCCGCACCGAAGACGAACT
GAGGGCCAAAAAGGGCCGTTTCGGGTCGGCGGTGGCCATGGATGAACGCACCGTGGTGACCAATTGCCACGTCATCGACG
AGATGTCGGTGATTCTGCTGCGCCAGGGCGGGCAGACCATGCGGGCGACGCCATCGGGCGGGGACGAGGCCACCGACCGC
TGCCTGATGACCGTTTCGCCCGGGCGTCTGTCGGCTGTCCCGGGAATTCGCGCCTGGGAGGATCTGCGGGTGGGCGAGAC
GGTCTATTCCATCGGCGCGCCCAAAGGACTGGAGGCGACCTTGGGCCAAGGCCTGGTCTCGGGACTGCGGACCATCAAGG
GCCTGCGCTACGTCCAGACCACGGCCCCCATTTCCCAGGGGTCCTCGGGGGGAGGGCTGTTCGACTCGGCGGGCAATCTG
GTGGGCATTACCACCTTTCACATCCGCGACGCCGACGGACTCAACTTCGCCATCGCCGCCGAGGATTTCTTCCGGTGA

Upstream 100 bases:

>100_bases
AGGGCTCGGCGCCGGAGGCTCCGCCCGCCGAGTAAGGCGCGCTGGAGACTGGTAACGGTAGCATCCCCGCTTCCTGAAAA
GGAGGCGGGGATGACTTTTT

Downstream 100 bases:

>100_bases
CGGCCGCCAAGCGCGTGGGGCGCGACGATTCCTTCATCGTCCTGCCCCTGGGGCCGCTGGGACTGGGGCTTCCCAAATGG
ATGCCCCTGGTGATTGTCTA

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTFLNRVKTLSGQGAIIFLVNPGAPQPGWSVKGEAMSSRWGKTMAMLIAMGGALPVQAACLARPSSTAELAQCSTAAAAG
DSVAARMLGDVMGDPTQRHYDPATALSWWEQAAAAGDGLALRRLFDAHWYGRGTPKDLAKARTYLAKAVAGGAQWARLVR
AVLAEGEEPGLAADLYNGLAAEGNCLAQLRLAHGHDRGGWVEKNRSQALYWANVAGLAGRNEPPPEDHPLFENRFHYRDC
TSEAYFLRQELAHNLASDLRGRVEESAAAWKPGRMPERQGPVEAPPAIGVTPVGLGSGAAAKLPDWRPLAASLQRPAGRS
RLGAEDVFATVGRSVYVVIAARTEDELRAKKGRFGSAVAMDERTVVTNCHVIDEMSVILLRQGGQTMRATPSGGDEATDR
CLMTVSPGRLSAVPGIRAWEDLRVGETVYSIGAPKGLEATLGQGLVSGLRTIKGLRYVQTTAPISQGSSGGGLFDSAGNL
VGITTFHIRDADGLNFAIAAEDFFR

Sequences:

>Translated_505_residues
MTFLNRVKTLSGQGAIIFLVNPGAPQPGWSVKGEAMSSRWGKTMAMLIAMGGALPVQAACLARPSSTAELAQCSTAAAAG
DSVAARMLGDVMGDPTQRHYDPATALSWWEQAAAAGDGLALRRLFDAHWYGRGTPKDLAKARTYLAKAVAGGAQWARLVR
AVLAEGEEPGLAADLYNGLAAEGNCLAQLRLAHGHDRGGWVEKNRSQALYWANVAGLAGRNEPPPEDHPLFENRFHYRDC
TSEAYFLRQELAHNLASDLRGRVEESAAAWKPGRMPERQGPVEAPPAIGVTPVGLGSGAAAKLPDWRPLAASLQRPAGRS
RLGAEDVFATVGRSVYVVIAARTEDELRAKKGRFGSAVAMDERTVVTNCHVIDEMSVILLRQGGQTMRATPSGGDEATDR
CLMTVSPGRLSAVPGIRAWEDLRVGETVYSIGAPKGLEATLGQGLVSGLRTIKGLRYVQTTAPISQGSSGGGLFDSAGNL
VGITTFHIRDADGLNFAIAAEDFFR
>Mature_504_residues
TFLNRVKTLSGQGAIIFLVNPGAPQPGWSVKGEAMSSRWGKTMAMLIAMGGALPVQAACLARPSSTAELAQCSTAAAAGD
SVAARMLGDVMGDPTQRHYDPATALSWWEQAAAAGDGLALRRLFDAHWYGRGTPKDLAKARTYLAKAVAGGAQWARLVRA
VLAEGEEPGLAADLYNGLAAEGNCLAQLRLAHGHDRGGWVEKNRSQALYWANVAGLAGRNEPPPEDHPLFENRFHYRDCT
SEAYFLRQELAHNLASDLRGRVEESAAAWKPGRMPERQGPVEAPPAIGVTPVGLGSGAAAKLPDWRPLAASLQRPAGRSR
LGAEDVFATVGRSVYVVIAARTEDELRAKKGRFGSAVAMDERTVVTNCHVIDEMSVILLRQGGQTMRATPSGGDEATDRC
LMTVSPGRLSAVPGIRAWEDLRVGETVYSIGAPKGLEATLGQGLVSGLRTIKGLRYVQTTAPISQGSSGGGLFDSAGNLV
GITTFHIRDADGLNFAIAAEDFFR

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=168, Percent_Identity=31.547619047619, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789630, Length=159, Percent_Identity=34.5911949685535, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786356, Length=154, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789629, Length=141, Percent_Identity=34.0425531914894, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 53564; Mature: 53433

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLNRVKTLSGQGAIIFLVNPGAPQPGWSVKGEAMSSRWGKTMAMLIAMGGALPVQAAC
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
LARPSSTAELAQCSTAAAAGDSVAARMLGDVMGDPTQRHYDPATALSWWEQAAAAGDGLA
HCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCHH
LRRLFDAHWYGRGTPKDLAKARTYLAKAVAGGAQWARLVRAVLAEGEEPGLAADLYNGLA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
AEGNCLAQLRLAHGHDRGGWVEKNRSQALYWANVAGLAGRNEPPPEDHPLFENRFHYRDC
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TSEAYFLRQELAHNLASDLRGRVEESAAAWKPGRMPERQGPVEAPPAIGVTPVGLGSGAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
AKLPDWRPLAASLQRPAGRSRLGAEDVFATVGRSVYVVIAARTEDELRAKKGRFGSAVAM
CCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEEEECCHHHHHHHCCCCCCEEEE
DERTVVTNCHVIDEMSVILLRQGGQTMRATPSGGDEATDRCLMTVSPGRLSAVPGIRAWE
CCCEEEEECEEHHHCEEEEECCCCCEEEECCCCCCHHHCCEEEEECCCCEECCCCCCCHH
DLRVGETVYSIGAPKGLEATLGQGLVSGLRTIKGLRYVQTTAPISQGSSGGGLFDSAGNL
HHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCE
VGITTFHIRDADGLNFAIAAEDFFR
EEEEEEEEECCCCCEEEEECHHHCC
>Mature Secondary Structure 
TFLNRVKTLSGQGAIIFLVNPGAPQPGWSVKGEAMSSRWGKTMAMLIAMGGALPVQAAC
CHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
LARPSSTAELAQCSTAAAAGDSVAARMLGDVMGDPTQRHYDPATALSWWEQAAAAGDGLA
HCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCHH
LRRLFDAHWYGRGTPKDLAKARTYLAKAVAGGAQWARLVRAVLAEGEEPGLAADLYNGLA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
AEGNCLAQLRLAHGHDRGGWVEKNRSQALYWANVAGLAGRNEPPPEDHPLFENRFHYRDC
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TSEAYFLRQELAHNLASDLRGRVEESAAAWKPGRMPERQGPVEAPPAIGVTPVGLGSGAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
AKLPDWRPLAASLQRPAGRSRLGAEDVFATVGRSVYVVIAARTEDELRAKKGRFGSAVAM
CCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEEEECCHHHHHHHCCCCCCEEEE
DERTVVTNCHVIDEMSVILLRQGGQTMRATPSGGDEATDRCLMTVSPGRLSAVPGIRAWE
CCCEEEEECEEHHHCEEEEECCCCCEEEECCCCCCHHHCCEEEEECCCCEECCCCCCCHH
DLRVGETVYSIGAPKGLEATLGQGLVSGLRTIKGLRYVQTTAPISQGSSGGGLFDSAGNL
HHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCE
VGITTFHIRDADGLNFAIAAEDFFR
EEEEEEEEECCCCCEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]