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The map label for this gene is coxS [H]

Identifier: 83311981

GI number: 83311981

Start: 3082293

End: 3082754

Strand: Reverse

Name: coxS [H]

Synonym: amb2882

Alternate gene names: 83311981

Gene position: 3082754-3082293 (Counterclockwise)

Preceding gene: 83311984

Following gene: 83311980

Centisome position: 62.06

GC content: 69.91

Gene sequence:

>462_bases
ATGCGTGTCGCGTTCACCCTGAACGGCCGCGAGGTGGAGGCCGAGGTGGAGCCCAACACCTTGCTGGTGGCGCTGCTGCG
CGAGGGCTTCGGCCTGACGGGGACCCATGTGGGCTGCGACACCGGCCAGTGCGGCGCCTGCACCGTTCACCTGGACGGCC
GCGCCGTCAAATCCTGCCTGATCCTGGCCGCCCAGGCCGACGGGCGCAGCGTTCTGACCATCGAGGGCGTCGCCGAGGGC
GGGACCCTTCACCCGCTGCAGGCGGCGTTCCGCGACCGTCATGCCTTGCAATGCGGTTTCTGCACGCCCGGCATGGTGAT
GAGCGGTCTGGATCTGGTCGCCCATCTGGACAGCCCCGACGAGGCGGCCATCCGCCACGGCCTGGACGGCAATCTGTGCC
GCTGCACCGGCTATCGCCCCATCGTCGAGGCCATCGCCCAGACCATCGGGGAGAAGGGCTGA

Upstream 100 bases:

>100_bases
CGTCGAGGCATGATTTAACGGCTATGGGCATCGGGACCGGTTTCCTTGCAACGGCGCCGATGATAGCGTCGTCCGGAGCG
CAAATCAAAGGAGCGAGCCC

Downstream 100 bases:

>100_bases
TGTTTCCCTTCGACTATCTCCGCCCCCAAAGCGTCGCCGAGGCCGTCTGTGCCCATGATGGCGAGGAGCGGCGCTATCTG
GCGGGAGGCCAGAGCCTGCT

Product: aerobic-type carbon monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRVAFTLNGREVEAEVEPNTLLVALLREGFGLTGTHVGCDTGQCGACTVHLDGRAVKSCLILAAQADGRSVLTIEGVAEG
GTLHPLQAAFRDRHALQCGFCTPGMVMSGLDLVAHLDSPDEAAIRHGLDGNLCRCTGYRPIVEAIAQTIGEKG

Sequences:

>Translated_153_residues
MRVAFTLNGREVEAEVEPNTLLVALLREGFGLTGTHVGCDTGQCGACTVHLDGRAVKSCLILAAQADGRSVLTIEGVAEG
GTLHPLQAAFRDRHALQCGFCTPGMVMSGLDLVAHLDSPDEAAIRHGLDGNLCRCTGYRPIVEAIAQTIGEKG
>Mature_153_residues
MRVAFTLNGREVEAEVEPNTLLVALLREGFGLTGTHVGCDTGQCGACTVHLDGRAVKSCLILAAQADGRSVLTIEGVAEG
GTLHPLQAAFRDRHALQCGFCTPGMVMSGLDLVAHLDSPDEAAIRHGLDGNLCRCTGYRPIVEAIAQTIGEKG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=155, Percent_Identity=41.2903225806452, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=39.4736842105263, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1789232, Length=150, Percent_Identity=46.6666666666667, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=38.5542168674699, Blast_Score=117, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=162, Percent_Identity=41.358024691358, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=43.1372549019608, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=40.2597402597403, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17737937, Length=153, Percent_Identity=43.1372549019608, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=35.625, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=35.625, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=35.7142857142857, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=35.7142857142857, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647193, Length=155, Percent_Identity=35.4838709677419, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16026; Mature: 16026

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAFTLNGREVEAEVEPNTLLVALLREGFGLTGTHVGCDTGQCGACTVHLDGRAVKSCL
CEEEEEECCEEEEEEECCCHHEEEEHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHEEE
ILAAQADGRSVLTIEGVAEGGTLHPLQAAFRDRHALQCGFCTPGMVMSGLDLVAHLDSPD
EEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEECCCCCHHHHHCCHHEEECCCCH
EAAIRHGLDGNLCRCTGYRPIVEAIAQTIGEKG
HHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVAFTLNGREVEAEVEPNTLLVALLREGFGLTGTHVGCDTGQCGACTVHLDGRAVKSCL
CEEEEEECCEEEEEEECCCHHEEEEHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHEEE
ILAAQADGRSVLTIEGVAEGGTLHPLQAAFRDRHALQCGFCTPGMVMSGLDLVAHLDSPD
EEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEECCCCCHHHHHCCHHEEECCCCH
EAAIRHGLDGNLCRCTGYRPIVEAIAQTIGEKG
HHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]