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The map label for this gene is actP [H]

Identifier: 83311826

GI number: 83311826

Start: 2913845

End: 2915530

Strand: Reverse

Name: actP [H]

Synonym: amb2727

Alternate gene names: 83311826

Gene position: 2915530-2913845 (Counterclockwise)

Preceding gene: 83311827

Following gene: 83311819

Centisome position: 58.7

GC content: 64.53

Gene sequence:

>1686_bases
ATGAAGACGACCAAGACCGCAATCGCGTCCGCGCTCGCCTTCGGCGGCACGGCGCTCCTGGCCTCCGCCGCCCTGGCGGC
CGGCGCCGACATGGGTGGGGCTGAAAAGCAGGCCACCAACTGGCACGCCATCATCATGTTCGTGATCTTCGTGGGCATGA
CCCTGGGCATCACCTACTGGGCGGCCGGACGCACCAAGACCGCCGCCGACTTCTACGCCGCCGGCGGTGGCATCACCGGT
TTCCAGAATGGCCTGGCCATCGCGGGCGACTACATGTCGGCCGCGTCGTTCCTGGGCATTTCCGCCCTGGTCTACGGCTC
GGGCTATGACGGCCTGATCTTCTCGGTGGGCTGGCTGGTCGGCTGGCCGATCATCCTGTTCCTGATCGCCGAGCGTCTGC
GCAACCTGGGCAAGTACACCTTCGCCGACGTGTGCGGCTATCGCCTTGCCCGCACGCCGATCCGCACCTTCGCCGCCACC
GGCTCGCTGATCGTCGTGATCTTCTATCTGATCGGCCAGATGGTCGGTGCTGGCCAGCTGATCAAGCTGCTGTTCGGCAT
GGACTACATCTACGCCGTGATGATCGTCGGCGCGCTGATGATGGTCTACGTCACCTTCGGCGGCATGGTTGCCACCACCT
GGGTACAGATCATCAAGGCCTGCCTGCTGCTGGGCGGCGCGACCTTCATCGCCTTCGGCGTGATGAGCCATTTCGGCTTC
TCGTTCGAGAAGCTGTTCGTCAAGGCCATCGAAGTGCATCCCAAGAAGGTGGCGATCATGGCGCCGGGCGCCCTGGTCAC
CAATCCGGTGGACGCCATCTCGCTGGGCATGGCGCTGATGTTCGGCACCGCCGGCCTGCCCCATATCCTCATGCGCTTCT
TCACCGTTCCCGATGCGCGTGAGGCCCGCAAGTCGGTGTTCTATGCCACCGGCTTCATCGGCTACTTCTACATCCTGACC
TTCATCATCGGCTTCGGCGCCATCACCCTGGTGGCGACCAATCCGGAATACCTGACCAAGGGCCTCGGCTCCCTGGATCT
GAAGGGCGGCAACAACATGGCCGCGGTGTGGCTGGCTCACGCTATCGGTGGTGACCTGTTCCTCGGCTTTATCTCGGCCG
TGGCCTTCGCCACCATCCTGGCGGTGGTGTCGGGCCTGACCCTGGCGGGCGCGTCGGCGATTTCGCACGACCTGTACGCC
AGCGTCATCATGCACGGCCAAGCCACCGAAGGCAGGGAAGTGACCGTCTCCAAGATCGCCTCCATCGGCCTCGGCATCAT
CGCCGTGCTGCTGGGTCTGGTCTTCGAGAAGCAGAACGTGGCGTTCATCGTGGCGCTCACCTTCTCGGTCGCGGCTTCGG
CCAACTTCCCGGTGCTGGTGCTGTCCATGTTCTGGGGCGGCCTGACCACCCGTGGCGCCGTGCTCGGCGGCATGATCGGC
CTGCTGATGTCGGTGATCATGGTGGTTCTGTCCAAGGCGGTGTGGGTGCAGAGCTTCGGCTTCAAGGCCGAGATCTTCCC
GTTCGCCTATCCGGCCCTGTTCTCGGTGCCGGCGGCCTTCTTCTTCTCCTGGTTGTTCTCGATCCTCGACAACAGCCCGC
AGGCTCAGGCTGAACGCGCCGCCTACGAAGCCCAGTCCATCCGGTCCGAGACCGGCCTGGGTGCCGAAGGCGCCGCCAGC
CACTAA

Upstream 100 bases:

>100_bases
GCGTCATCTTGTCGGCCATCGCGCTGACCGGCATCTATGTCTATCGCGCCAATGGCGAGTTCGACGACATGAACCGCCAG
ATTCTCGAGGATTCCCGCTG

Downstream 100 bases:

>100_bases
GGCATGGATACGGTTTGAAGGGAGGGGCATCGGGAAACCGATGCCCTTCTTTCATGGGAAATCCATGAAAAAAGGGCGCC
TACCACGAGGGTAGGCGCCA

Product: symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKTTKTAIASALAFGGTALLASAALAAGADMGGAEKQATNWHAIIMFVIFVGMTLGITYWAAGRTKTAADFYAAGGGITG
FQNGLAIAGDYMSAASFLGISALVYGSGYDGLIFSVGWLVGWPIILFLIAERLRNLGKYTFADVCGYRLARTPIRTFAAT
GSLIVVIFYLIGQMVGAGQLIKLLFGMDYIYAVMIVGALMMVYVTFGGMVATTWVQIIKACLLLGGATFIAFGVMSHFGF
SFEKLFVKAIEVHPKKVAIMAPGALVTNPVDAISLGMALMFGTAGLPHILMRFFTVPDAREARKSVFYATGFIGYFYILT
FIIGFGAITLVATNPEYLTKGLGSLDLKGGNNMAAVWLAHAIGGDLFLGFISAVAFATILAVVSGLTLAGASAISHDLYA
SVIMHGQATEGREVTVSKIASIGLGIIAVLLGLVFEKQNVAFIVALTFSVAASANFPVLVLSMFWGGLTTRGAVLGGMIG
LLMSVIMVVLSKAVWVQSFGFKAEIFPFAYPALFSVPAAFFFSWLFSILDNSPQAQAERAAYEAQSIRSETGLGAEGAAS
H

Sequences:

>Translated_561_residues
MKTTKTAIASALAFGGTALLASAALAAGADMGGAEKQATNWHAIIMFVIFVGMTLGITYWAAGRTKTAADFYAAGGGITG
FQNGLAIAGDYMSAASFLGISALVYGSGYDGLIFSVGWLVGWPIILFLIAERLRNLGKYTFADVCGYRLARTPIRTFAAT
GSLIVVIFYLIGQMVGAGQLIKLLFGMDYIYAVMIVGALMMVYVTFGGMVATTWVQIIKACLLLGGATFIAFGVMSHFGF
SFEKLFVKAIEVHPKKVAIMAPGALVTNPVDAISLGMALMFGTAGLPHILMRFFTVPDAREARKSVFYATGFIGYFYILT
FIIGFGAITLVATNPEYLTKGLGSLDLKGGNNMAAVWLAHAIGGDLFLGFISAVAFATILAVVSGLTLAGASAISHDLYA
SVIMHGQATEGREVTVSKIASIGLGIIAVLLGLVFEKQNVAFIVALTFSVAASANFPVLVLSMFWGGLTTRGAVLGGMIG
LLMSVIMVVLSKAVWVQSFGFKAEIFPFAYPALFSVPAAFFFSWLFSILDNSPQAQAERAAYEAQSIRSETGLGAEGAAS
H
>Mature_561_residues
MKTTKTAIASALAFGGTALLASAALAAGADMGGAEKQATNWHAIIMFVIFVGMTLGITYWAAGRTKTAADFYAAGGGITG
FQNGLAIAGDYMSAASFLGISALVYGSGYDGLIFSVGWLVGWPIILFLIAERLRNLGKYTFADVCGYRLARTPIRTFAAT
GSLIVVIFYLIGQMVGAGQLIKLLFGMDYIYAVMIVGALMMVYVTFGGMVATTWVQIIKACLLLGGATFIAFGVMSHFGF
SFEKLFVKAIEVHPKKVAIMAPGALVTNPVDAISLGMALMFGTAGLPHILMRFFTVPDAREARKSVFYATGFIGYFYILT
FIIGFGAITLVATNPEYLTKGLGSLDLKGGNNMAAVWLAHAIGGDLFLGFISAVAFATILAVVSGLTLAGASAISHDLYA
SVIMHGQATEGREVTVSKIASIGLGIIAVLLGLVFEKQNVAFIVALTFSVAASANFPVLVLSMFWGGLTTRGAVLGGMIG
LLMSVIMVVLSKAVWVQSFGFKAEIFPFAYPALFSVPAAFFFSWLFSILDNSPQAQAERAAYEAQSIRSETGLGAEGAAS
H

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=530, Percent_Identity=20.5660377358491, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1790503, Length=561, Percent_Identity=65.4188948306595, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=528, Percent_Identity=25.3787878787879, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59026; Mature: 59026

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA