Click here to switch to the map view.

The map label for this gene is cbiD

Identifier: 83311741

GI number: 83311741

Start: 2830284

End: 2831357

Strand: Reverse

Name: cbiD

Synonym: amb2642

Alternate gene names: 83311741

Gene position: 2831357-2830284 (Counterclockwise)

Preceding gene: 83311742

Following gene: 83311729

Centisome position: 57.0

GC content: 68.34

Gene sequence:

>1074_bases
GTGGCTGACGAACAAGCACTGCGACAGGGCTGGACTACCGGGGCCTGCGCCACAGCGGCGGCCAAGGCGGCGTGCTGTGC
GTTGCTGGGTGATGGCTTTCCCGATCCGGTCGGCATCGACCTGCCGGGGGGGCGCACGCCGGCCTTTGCCCTGGCCTTGG
CCGAGATGGGGGAGGGCTGGGCCCGGGCTGGAATCGTCAAGGATGCCGGTGACGATCCGGACGTAACCCATGGTGCCACC
ATCATCGCCACTCTGCGCCATGGGATTGCCGGGGCCGGCCTGGTGTTCAGGGCAGGGCGGGGCGTTGGGATTGTGACCCG
GCCGGGTCTGCCGCTGGCCGTCGGCGAGCCGGCGATCAATCCCGTTCCCCGTCGGCTGATGGCTGAGGCCGTGGCCGCCA
TCGCCGCCCGTCACGGCATGGCCTGCGACCTGGAGATCGAGATTTCCGTGCCGGGCGGTGAGGACATCGCCCTTCGCACC
TGGAATCCCCGCCTCGGCATTCTGGGCGGCATTTCCATTTTAGGGACCACCGGCGTGGTCATTCCTTATTCCTGCTCCGC
CTGGATTCACTCCATCCAGCGCGGCATCGACGTGGCTCGGGCCTGTGGATTGATCCATGTGGCCGGCTGCGTCGGTTCCA
CCTCGGAGAAGGCGGTGCGCAAGGTGCGCGGGCTGGGAGAGGAGGCGATCATCGACATGGGTGATTTCGCCGGCGGCATG
TTGAAATATCTGCGTCGCCATCCCATTCCCCGCGTCACCATCGCCGGCGGCTTCGCCAAGATGTGCAAGCTGGCGGCGGG
TCAGATGGATTTGCATTCAAGCCGCTCGCAGGTGGACATGGTCTGGCTGGCCGCCCAACTGAGGTCGCTGGGGGCGGATG
CGGCCCTGGTCGCCGCCTCGGCCCAGGCCAACACCGCCCTGGAGGTGCTGGAACTGGCGGAGGGATTCCCCCTGGGCCAG
GCCATCGCCCGCCAGGCCCGGGCGGCGGCGCGGGAGGTGCTCGATAATCCCGAGGTCAGCCTCGACGTGCTGGTGGTCGA
TCGCCAGGGCCGGGTGATCGGCGACGCTCACTGA

Upstream 100 bases:

>100_bases
TTTGGCGTGGTGCGGAAACCGACGCTGGACGGCAACGCCTGATCTTGTCCTCATGAATTTCATGCTATGACGTGCCGGAC
GTATTTGGCGGCGGACGCTC

Downstream 100 bases:

>100_bases
TTTGTGGGGGGCTAGGCCCCTTGATCAGATGCCCCTGACCCAAGCCGCTGCGTCTTCCGCCGAACCGGCGCATGCCGTTT
CGGGGCGGAGGGGTCGTTCC

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MADEQALRQGWTTGACATAAAKAACCALLGDGFPDPVGIDLPGGRTPAFALALAEMGEGWARAGIVKDAGDDPDVTHGAT
IIATLRHGIAGAGLVFRAGRGVGIVTRPGLPLAVGEPAINPVPRRLMAEAVAAIAARHGMACDLEIEISVPGGEDIALRT
WNPRLGILGGISILGTTGVVIPYSCSAWIHSIQRGIDVARACGLIHVAGCVGSTSEKAVRKVRGLGEEAIIDMGDFAGGM
LKYLRRHPIPRVTIAGGFAKMCKLAAGQMDLHSSRSQVDMVWLAAQLRSLGADAALVAASAQANTALEVLELAEGFPLGQ
AIARQARAAAREVLDNPEVSLDVLVVDRQGRVIGDAH

Sequences:

>Translated_357_residues
MADEQALRQGWTTGACATAAAKAACCALLGDGFPDPVGIDLPGGRTPAFALALAEMGEGWARAGIVKDAGDDPDVTHGAT
IIATLRHGIAGAGLVFRAGRGVGIVTRPGLPLAVGEPAINPVPRRLMAEAVAAIAARHGMACDLEIEISVPGGEDIALRT
WNPRLGILGGISILGTTGVVIPYSCSAWIHSIQRGIDVARACGLIHVAGCVGSTSEKAVRKVRGLGEEAIIDMGDFAGGM
LKYLRRHPIPRVTIAGGFAKMCKLAAGQMDLHSSRSQVDMVWLAAQLRSLGADAALVAASAQANTALEVLELAEGFPLGQ
AIARQARAAAREVLDNPEVSLDVLVVDRQGRVIGDAH
>Mature_356_residues
ADEQALRQGWTTGACATAAAKAACCALLGDGFPDPVGIDLPGGRTPAFALALAEMGEGWARAGIVKDAGDDPDVTHGATI
IATLRHGIAGAGLVFRAGRGVGIVTRPGLPLAVGEPAINPVPRRLMAEAVAAIAARHGMACDLEIEISVPGGEDIALRTW
NPRLGILGGISILGTTGVVIPYSCSAWIHSIQRGIDVARACGLIHVAGCVGSTSEKAVRKVRGLGEEAIIDMGDFAGGML
KYLRRHPIPRVTIAGGFAKMCKLAAGQMDLHSSRSQVDMVWLAAQLRSLGADAALVAASAQANTALEVLELAEGFPLGQA
IARQARAAAREVLDNPEVSLDVLVVDRQGRVIGDAH

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_MAGSA (Q2W3X9)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422005.1
- ProteinModelPortal:   Q2W3X9
- SMR:   Q2W3X9
- STRING:   Q2W3X9
- GeneID:   3804750
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2642
- NMPDR:   fig|342108.5.peg.2338
- eggNOG:   COG1903
- HOGENOM:   HBG705387
- OMA:   RRGWTTG
- ProtClustDB:   PRK00075
- BioCyc:   MMAG342108:AMB2642-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 36766; Mature: 36635

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEQALRQGWTTGACATAAAKAACCALLGDGFPDPVGIDLPGGRTPAFALALAEMGEGW
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCH
ARAGIVKDAGDDPDVTHGATIIATLRHGIAGAGLVFRAGRGVGIVTRPGLPLAVGEPAIN
HHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCEEECCCCCC
PVPRRLMAEAVAAIAARHGMACDLEIEISVPGGEDIALRTWNPRLGILGGISILGTTGVV
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCCCHHCCHHHHCCCCEE
IPYSCSAWIHSIQRGIDVARACGLIHVAGCVGSTSEKAVRKVRGLGEEAIIDMGDFAGGM
EECCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCHHHEEECHHHHHHH
LKYLRRHPIPRVTIAGGFAKMCKLAAGQMDLHSSRSQVDMVWLAAQLRSLGADAALVAAS
HHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
AQANTALEVLELAEGFPLGQAIARQARAAAREVLDNPEVSLDVLVVDRQGRVIGDAH
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEECCCC
>Mature Secondary Structure 
ADEQALRQGWTTGACATAAAKAACCALLGDGFPDPVGIDLPGGRTPAFALALAEMGEGW
CCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCH
ARAGIVKDAGDDPDVTHGATIIATLRHGIAGAGLVFRAGRGVGIVTRPGLPLAVGEPAIN
HHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCEEECCCCCC
PVPRRLMAEAVAAIAARHGMACDLEIEISVPGGEDIALRTWNPRLGILGGISILGTTGVV
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCCCHHCCHHHHCCCCEE
IPYSCSAWIHSIQRGIDVARACGLIHVAGCVGSTSEKAVRKVRGLGEEAIIDMGDFAGGM
EECCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCHHHEEECHHHHHHH
LKYLRRHPIPRVTIAGGFAKMCKLAAGQMDLHSSRSQVDMVWLAAQLRSLGADAALVAAS
HHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
AQANTALEVLELAEGFPLGQAIARQARAAAREVLDNPEVSLDVLVVDRQGRVIGDAH
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA