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The map label for this gene is lolC [H]

Identifier: 83311671

GI number: 83311671

Start: 2756798

End: 2758042

Strand: Reverse

Name: lolC [H]

Synonym: amb2572

Alternate gene names: 83311671

Gene position: 2758042-2756798 (Counterclockwise)

Preceding gene: 83311672

Following gene: 83311670

Centisome position: 55.53

GC content: 64.98

Gene sequence:

>1245_bases
ATGATTTTCAATTCGTTCGAGCGCATGGTGGCGTTCCGCTATCTGCGGGCCCGGCGCAAGGAAGGCTTCATTTCGGTGAT
CGCCGGCTTCTCCCTTGCGGGGATCGGCCTGGGCGTCGCCACGCTGATCGTGGTGATGGCGGTGATGAACGGCTTTCGCC
ACGAGTTGCTGGGCCGCATTCTCGGCATCAATGGCCATATCGGCGTCTATGGCAGCGGCGCGCCGCTGTCGGGCTACGAC
CCGCTGGCCGACTCCATCCGCAAGCTGCCGGGCGTGACCCGGGTGATTCCCACCGCCGAAGGCCAGGTCTTCGCCACCTC
GTCCGGCGGCGGAACGGGGGCCATCGTGCGCGGCGTGCGCGGCCAAGACCTGCTGACCCGGCCGGTCTTCCAGAAGAAGT
ACCGCGGCAATCCCGCCGATTTCGCTGGCGACGACGCGGTGGTGATCGGCAAGCGCCTGGCCGACAAGCTGGGCGTGCGC
ATCGGCGATTCCATCTCGCTGATCTCGCCCAAGGGCAACGTCACCGCCTTCGGCACCGTGCCGCGCATGCGCGGCTACCG
CGTGGTGGGAACCTTTGACGTCGGCATGTTCGAATACGATTCCGGCTTCATCTTCATGCCGCTGGAGGCTGCCCAGACCT
ATTTCCGGCTGCCCGAACAGGTGACTCAGATCGAGGTGTTCCTGGAAAACCCCGACATGGTGCCCGAGACCCGCAAGGCC
ATCTGGGACCTGACCGGCACCACCGCCACCATCTATGACTGGCAGCAGGCCAACGCCAACTTCTTCAACGCCATCCAGGT
AGAGCGGAACGTCATGTTCCTGATTCTCACCCTGATCATCCTGGTGGCGGCCTTCAACATCATCTCCAGCCTGATCATGC
TGGTGAAGGACAAGGGGCGCGACATCGCCATCCTGCGCACCATGGGGGCGACGCGGGGGATGATCCTGCGCATCTTCTTC
CTGGCCGGGGCCTCGGTGGGGGTGGTGGGCACGGTGGCGGGCACCGTGCTGGGGGTGGCCTTCGCCACCAACATCGAAAA
CATCCGCCAGTTCATCCAGTCGATCATCGGGCGCGAGCTGTTCGCCGCCGAGATCTACTTCCTCACCCAACTGCCGGCCC
GGGTCGAGACGCGCGAGGTGGTCACCGTGGTGCTGATGGCCCTGGGCCTGTCCTTCGCTGCCACCATCTACCCGGCCTGG
CGCGCCGCCAAGCTCGATCCGGTGGAGGCCCTGCGCTATGAATAA

Upstream 100 bases:

>100_bases
CGCCCTGGCCGAGGCCTGCGCCAGGCGCGGCGTGCGGTAGCGTTGCCAAGCGGGCCGCCTTTGCCTATTGTCCCCGTCCA
GGATTGATCGGCGGGGTTCC

Downstream 100 bases:

>100_bases
CCACGGCCTGAAGCTGGACAACATCCGCCGCGCCTTCAAGCAGGGCAAGGATGACCTGGAGGTGCTGAAAGGCGCCAACC
TGGAGATCAGGGCGGGAGAG

Product: ABC-type transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIFNSFERMVAFRYLRARRKEGFISVIAGFSLAGIGLGVATLIVVMAVMNGFRHELLGRILGINGHIGVYGSGAPLSGYD
PLADSIRKLPGVTRVIPTAEGQVFATSSGGGTGAIVRGVRGQDLLTRPVFQKKYRGNPADFAGDDAVVIGKRLADKLGVR
IGDSISLISPKGNVTAFGTVPRMRGYRVVGTFDVGMFEYDSGFIFMPLEAAQTYFRLPEQVTQIEVFLENPDMVPETRKA
IWDLTGTTATIYDWQQANANFFNAIQVERNVMFLILTLIILVAAFNIISSLIMLVKDKGRDIAILRTMGATRGMILRIFF
LAGASVGVVGTVAGTVLGVAFATNIENIRQFIQSIIGRELFAAEIYFLTQLPARVETREVVTVVLMALGLSFAATIYPAW
RAAKLDPVEALRYE

Sequences:

>Translated_414_residues
MIFNSFERMVAFRYLRARRKEGFISVIAGFSLAGIGLGVATLIVVMAVMNGFRHELLGRILGINGHIGVYGSGAPLSGYD
PLADSIRKLPGVTRVIPTAEGQVFATSSGGGTGAIVRGVRGQDLLTRPVFQKKYRGNPADFAGDDAVVIGKRLADKLGVR
IGDSISLISPKGNVTAFGTVPRMRGYRVVGTFDVGMFEYDSGFIFMPLEAAQTYFRLPEQVTQIEVFLENPDMVPETRKA
IWDLTGTTATIYDWQQANANFFNAIQVERNVMFLILTLIILVAAFNIISSLIMLVKDKGRDIAILRTMGATRGMILRIFF
LAGASVGVVGTVAGTVLGVAFATNIENIRQFIQSIIGRELFAAEIYFLTQLPARVETREVVTVVLMALGLSFAATIYPAW
RAAKLDPVEALRYE
>Mature_414_residues
MIFNSFERMVAFRYLRARRKEGFISVIAGFSLAGIGLGVATLIVVMAVMNGFRHELLGRILGINGHIGVYGSGAPLSGYD
PLADSIRKLPGVTRVIPTAEGQVFATSSGGGTGAIVRGVRGQDLLTRPVFQKKYRGNPADFAGDDAVVIGKRLADKLGVR
IGDSISLISPKGNVTAFGTVPRMRGYRVVGTFDVGMFEYDSGFIFMPLEAAQTYFRLPEQVTQIEVFLENPDMVPETRKA
IWDLTGTTATIYDWQQANANFFNAIQVERNVMFLILTLIILVAAFNIISSLIMLVKDKGRDIAILRTMGATRGMILRIFF
LAGASVGVVGTVAGTVLGVAFATNIENIRQFIQSIIGRELFAAEIYFLTQLPARVETREVVTVVLMALGLSFAATIYPAW
RAAKLDPVEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=405, Percent_Identity=32.0987654320988, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787360, Length=418, Percent_Identity=33.0143540669856, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45107; Mature: 45107

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFNSFERMVAFRYLRARRKEGFISVIAGFSLAGIGLGVATLIVVMAVMNGFRHELLGRI
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGINGHIGVYGSGAPLSGYDPLADSIRKLPGVTRVIPTAEGQVFATSSGGGTGAIVRGVR
CCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCEEECCC
GQDLLTRPVFQKKYRGNPADFAGDDAVVIGKRLADKLGVRIGDSISLISPKGNVTAFGTV
CCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHCCEECCCEEEECCCCCEEEEECC
PRMRGYRVVGTFDVGMFEYDSGFIFMPLEAAQTYFRLPEQVTQIEVFLENPDMVPETRKA
CCCCCEEEEEEEECCEEEECCCEEEEEHHHHHHHHHCHHHHEEEEEEECCCCCCCHHHHH
IWDLTGTTATIYDWQQANANFFNAIQVERNVMFLILTLIILVAAFNIISSLIMLVKDKGR
HHHCCCCEEEEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIAILRTMGATRGMILRIFFLAGASVGVVGTVAGTVLGVAFATNIENIRQFIQSIIGREL
CEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHH
FAAEIYFLTQLPARVETREVVTVVLMALGLSFAATIYPAWRAAKLDPVEALRYE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MIFNSFERMVAFRYLRARRKEGFISVIAGFSLAGIGLGVATLIVVMAVMNGFRHELLGRI
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGINGHIGVYGSGAPLSGYDPLADSIRKLPGVTRVIPTAEGQVFATSSGGGTGAIVRGVR
CCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCEEECCC
GQDLLTRPVFQKKYRGNPADFAGDDAVVIGKRLADKLGVRIGDSISLISPKGNVTAFGTV
CCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHCCEECCCEEEECCCCCEEEEECC
PRMRGYRVVGTFDVGMFEYDSGFIFMPLEAAQTYFRLPEQVTQIEVFLENPDMVPETRKA
CCCCCEEEEEEEECCEEEECCCEEEEEHHHHHHHHHCHHHHEEEEEEECCCCCCCHHHHH
IWDLTGTTATIYDWQQANANFFNAIQVERNVMFLILTLIILVAAFNIISSLIMLVKDKGR
HHHCCCCEEEEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIAILRTMGATRGMILRIFFLAGASVGVVGTVAGTVLGVAFATNIENIRQFIQSIIGREL
CEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHH
FAAEIYFLTQLPARVETREVVTVVLMALGLSFAATIYPAWRAAKLDPVEALRYE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]