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The map label for this gene is purE [H]

Identifier: 83311301

GI number: 83311301

Start: 2398264

End: 2398785

Strand: Reverse

Name: purE [H]

Synonym: amb2202

Alternate gene names: 83311301

Gene position: 2398785-2398264 (Counterclockwise)

Preceding gene: 83311304

Following gene: 83311300

Centisome position: 48.29

GC content: 70.69

Gene sequence:

>522_bases
ATGGTCAAAGCGGCCCCCATCCAGGTCGGCATCATCATGGGCAGCCAGTCCGACTGGGAGACCATGCGCCATGCCGCCCA
GGTGCTCAGCGACCTGGGCATCGCCTTCGAGACCCGGGTGGTCTCGGCCCATCGCACCCCCAAGCGCCTTTACGACTACG
CCACCTCGGCCAAGGGCCGCGGCCTCAAGGTGATCATCGCCGGTGCCGGCGGGGCCGCCCATCTGCCGGGAATGGCCGCC
GCCATGACCACGTTGCCGGTGTTCGGCGTCCCGGTGGAGAGCAAGGCGCTGAAGGGCCTGGATTCGCTGCTGTCCATCGT
CCAGATGCCCGGCGGCATCCCGGTGGGAACCCTGGCCATCGGCAAGGCGGGCGCCACCAATGCCGCCCTGCTGGCCGGCG
CGGTGATCGCCCTGATGGACGAGGCCGTGGACAAGGCGCTGGAGGCCTGGCGCGCCCGCCAGACCGAGTCCGTGGCCGAG
GCCCCGGTGGACCCCGATTCTCCCGACCTGATCCGCCCGTGA

Upstream 100 bases:

>100_bases
AGGGGCACTGTCTGAAATTTCGCCAATACGTCCTTGCGTCCGGGACGCGGCTGCATATAATTCCGCCCTTTCTCTTCCCT
AGGCAGGGCAAGGAACGAGC

Downstream 100 bases:

>100_bases
GCCACGATCCCGCGTCGTCTCCGCTGCCGCCCGGCAGCACCATCGGCATTATCGGCGGCGGCCAGTTGGGCCGCATGGCC
GCCCTGGCGGCGGCGCGGCT

Product: phosphoribosylcarboxyaminoimidazole mutase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MVKAAPIQVGIIMGSQSDWETMRHAAQVLSDLGIAFETRVVSAHRTPKRLYDYATSAKGRGLKVIIAGAGGAAHLPGMAA
AMTTLPVFGVPVESKALKGLDSLLSIVQMPGGIPVGTLAIGKAGATNAALLAGAVIALMDEAVDKALEAWRARQTESVAE
APVDPDSPDLIRP

Sequences:

>Translated_173_residues
MVKAAPIQVGIIMGSQSDWETMRHAAQVLSDLGIAFETRVVSAHRTPKRLYDYATSAKGRGLKVIIAGAGGAAHLPGMAA
AMTTLPVFGVPVESKALKGLDSLLSIVQMPGGIPVGTLAIGKAGATNAALLAGAVIALMDEAVDKALEAWRARQTESVAE
APVDPDSPDLIRP
>Mature_173_residues
MVKAAPIQVGIIMGSQSDWETMRHAAQVLSDLGIAFETRVVSAHRTPKRLYDYATSAKGRGLKVIIAGAGGAAHLPGMAA
AMTTLPVFGVPVESKALKGLDSLLSIVQMPGGIPVGTLAIGKAGATNAALLAGAVIALMDEAVDKALEAWRARQTESVAE
APVDPDSPDLIRP

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=163, Percent_Identity=58.8957055214724, Blast_Score=159, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=57.3333333333333, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17804; Mature: 17804

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAAPIQVGIIMGSQSDWETMRHAAQVLSDLGIAFETRVVSAHRTPKRLYDYATSAKGR
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
GLKVIIAGAGGAAHLPGMAAAMTTLPVFGVPVESKALKGLDSLLSIVQMPGGIPVGTLAI
CEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GKAGATNAALLAGAVIALMDEAVDKALEAWRARQTESVAEAPVDPDSPDLIRP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVKAAPIQVGIIMGSQSDWETMRHAAQVLSDLGIAFETRVVSAHRTPKRLYDYATSAKGR
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
GLKVIIAGAGGAAHLPGMAAAMTTLPVFGVPVESKALKGLDSLLSIVQMPGGIPVGTLAI
CEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GKAGATNAALLAGAVIALMDEAVDKALEAWRARQTESVAEAPVDPDSPDLIRP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]