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The map label for this gene is ctaC [H]

Identifier: 83311269

GI number: 83311269

Start: 2354260

End: 2355141

Strand: Reverse

Name: ctaC [H]

Synonym: amb2170

Alternate gene names: 83311269

Gene position: 2355141-2354260 (Counterclockwise)

Preceding gene: 83311274

Following gene: 83311268

Centisome position: 47.41

GC content: 63.15

Gene sequence:

>882_bases
ATGACTGCGGATGAAGAGACGGCAGGGAGGGACATTCGCATGAACAGGTCCACTCAGGCCCTCATGGCGGCGGCTGTGTT
AATTGGTCTGGCACCGGTGGCCATGGCCGGGGAGCCGCAACCTTGGGCCCTCTCGTTCCAGCACGGGGTCTCCCCCACCA
TGGAACGCATCACCTCATTGGCCACCTTCATCAACGGCGTGATCGTGGTGATCACTCTGCTGGTATCCGGGCTGCTGCTT
TATGCCTGCACCCGCTTCAGGGCCGACCGCAACCCCAAGCCGGCCACCTGGTCGCACAACACGCCGCTGGAGGTCGTCTG
GACCGCCATACCGGCGGTGATCCTGCTGCTGATCGCCATACCATCGTTCCGGCTGCTCTACTTCATGGACCGCGTCCATG
ACGCCGACATGACGCTGAAGATCGTCGGCCACCAGTGGTACTGGACCTACGAGTATCCCGATCACGACTTCAAGTTCGAC
AGCAACATGGTGCAGGCCGAGGACCTAAAGCCCGGCCAGCCGCGCCTGCTGACCGCCGACAACACCCTGGTGGTGCCGGC
CGGCGTGCCCATCCGCCTGCAGATGACCGCCGACGACGTGATCCATTCGTGGTCGGTGCCGGCGTTCGGCATCAAGACCG
ACGCAGTGCCCGGACGGCTTAACGAGACCTGGGTGCAGGTCAACGAGCCCGGCACCTATTACGGCCAATGTTCGCAATTG
TGCGGCGTCAACCATGGCTTCATGCCGGTGCACGTCAAGGCGGTGCCCAAGGAAGAATTCCTGGCCTGGGTCGCCCAGGC
CAAGAAGACCTATGCCCACCTGGACGGCAGCCGTCCGGAAACTGCCGTCGCACTTGCCGAAACCGGGGGGAAAAGTCCAT
GA

Upstream 100 bases:

>100_bases
GCCTTCGGGTTTTTTGCCCCTGGGGCTTGGAATGCCCAAGCAGCAACCCCACTAATAAGAATGACTTTCAGACGCAGTAA
TTCATCCGTGAGTGGGAGAG

Downstream 100 bases:

>100_bases
GCACCGCAATCACCCATGATCACGGGCACGCCCAGCCCCACGGCTGGCGGCGCTGGCTCTATTCCACCAACCACAAGGAC
ATCGGCACGCTGTACCTGAT

Product: Heme/copper-type cytochrome/quinol oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTADEETAGRDIRMNRSTQALMAAAVLIGLAPVAMAGEPQPWALSFQHGVSPTMERITSLATFINGVIVVITLLVSGLLL
YACTRFRADRNPKPATWSHNTPLEVVWTAIPAVILLLIAIPSFRLLYFMDRVHDADMTLKIVGHQWYWTYEYPDHDFKFD
SNMVQAEDLKPGQPRLLTADNTLVVPAGVPIRLQMTADDVIHSWSVPAFGIKTDAVPGRLNETWVQVNEPGTYYGQCSQL
CGVNHGFMPVHVKAVPKEEFLAWVAQAKKTYAHLDGSRPETAVALAETGGKSP

Sequences:

>Translated_293_residues
MTADEETAGRDIRMNRSTQALMAAAVLIGLAPVAMAGEPQPWALSFQHGVSPTMERITSLATFINGVIVVITLLVSGLLL
YACTRFRADRNPKPATWSHNTPLEVVWTAIPAVILLLIAIPSFRLLYFMDRVHDADMTLKIVGHQWYWTYEYPDHDFKFD
SNMVQAEDLKPGQPRLLTADNTLVVPAGVPIRLQMTADDVIHSWSVPAFGIKTDAVPGRLNETWVQVNEPGTYYGQCSQL
CGVNHGFMPVHVKAVPKEEFLAWVAQAKKTYAHLDGSRPETAVALAETGGKSP
>Mature_292_residues
TADEETAGRDIRMNRSTQALMAAAVLIGLAPVAMAGEPQPWALSFQHGVSPTMERITSLATFINGVIVVITLLVSGLLLY
ACTRFRADRNPKPATWSHNTPLEVVWTAIPAVILLLIAIPSFRLLYFMDRVHDADMTLKIVGHQWYWTYEYPDHDFKFDS
NMVQAEDLKPGQPRLLTADNTLVVPAGVPIRLQMTADDVIHSWSVPAFGIKTDAVPGRLNETWVQVNEPGTYYGQCSQLC
GVNHGFMPVHVKAVPKEEFLAWVAQAKKTYAHLDGSRPETAVALAETGGKSP

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=218, Percent_Identity=45.4128440366972, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1786635, Length=221, Percent_Identity=24.8868778280543, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6226540, Length=246, Percent_Identity=41.0569105691057, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32308; Mature: 32176

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADEETAGRDIRMNRSTQALMAAAVLIGLAPVAMAGEPQPWALSFQHGVSPTMERITSL
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHH
ATFINGVIVVITLLVSGLLLYACTRFRADRNPKPATWSHNTPLEVVWTAIPAVILLLIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PSFRLLYFMDRVHDADMTLKIVGHQWYWTYEYPDHDFKFDSNMVQAEDLKPGQPRLLTAD
HHHHHHHHHHHHCCCCEEEEEEECEEEEEEECCCCCCCCCCCCEECCCCCCCCCEEEECC
NTLVVPAGVPIRLQMTADDVIHSWSVPAFGIKTDAVPGRLNETWVQVNEPGTYYGQCSQL
CEEEEECCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
CGVNHGFMPVHVKAVPKEEFLAWVAQAKKTYAHLDGSRPETAVALAETGGKSP
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TADEETAGRDIRMNRSTQALMAAAVLIGLAPVAMAGEPQPWALSFQHGVSPTMERITSL
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHH
ATFINGVIVVITLLVSGLLLYACTRFRADRNPKPATWSHNTPLEVVWTAIPAVILLLIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PSFRLLYFMDRVHDADMTLKIVGHQWYWTYEYPDHDFKFDSNMVQAEDLKPGQPRLLTAD
HHHHHHHHHHHHCCCCEEEEEEECEEEEEEECCCCCCCCCCCCEECCCCCCCCCEEEECC
NTLVVPAGVPIRLQMTADDVIHSWSVPAFGIKTDAVPGRLNETWVQVNEPGTYYGQCSQL
CEEEEECCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
CGVNHGFMPVHVKAVPKEEFLAWVAQAKKTYAHLDGSRPETAVALAETGGKSP
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA