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The map label for this gene is ctaD [H]

Identifier: 83311268

GI number: 83311268

Start: 2352665

End: 2354263

Strand: Reverse

Name: ctaD [H]

Synonym: amb2169

Alternate gene names: 83311268

Gene position: 2354263-2352665 (Counterclockwise)

Preceding gene: 83311269

Following gene: 83311267

Centisome position: 47.4

GC content: 64.23

Gene sequence:

>1599_bases
ATGAGCACCGCAATCACCCATGATCACGGGCACGCCCAGCCCCACGGCTGGCGGCGCTGGCTCTATTCCACCAACCACAA
GGACATCGGCACGCTGTACCTGATCTTCTCGGTGATCGCCGGGCTGCTGGGGGGCGCCATGTCCATCGTCATCCGCATGC
AGCTGGCCCATCCGGGCGGCACCATCTTCAACGGCGACTGGCACATGTACAATGTGTTCGTCACCGCCCACGCGCTGACC
ATGGTGTTCTTCACGGTGATGCCCGCCCTGATCGGCGGCTTCGGCAACTGGTTCGTGCCGCTGATGATCGGCGCGCCGGA
CATGGCCTTTCCCCGGCTGAACAACATCAGCTTCTGGCTGCTGCCCCCCGCCTTCATCATGATGCTGCTGTCCATGGTCG
AAGGCGCCGGAGCCGGCACCGGCTGGACGCTCTATCCCCCGCTGTCCACCGCCTATCACCCCGACGCCTCGGTGGACTTC
GCCATTCTGGGCCTGCATCTGGCCGGCATCAGTTCGGTGCTGGGTGCCATCAACTTCGTCTGCACCATTCTCAACATGCG
CGCGCCGGGCATGACCATGCACCGCATGCCGCTGTTCGTCTGGGCCATGCTGGTCACCGCCTTCCTGCTGCTGCTGTCCA
TTCCGGTGCTGGCGGGCGCGCTGACCATGCTGCTCACCGACCGCAATTTCGGCACCACCTTCTTCGCCCCGGCCGGCGGC
GGCGATCCCCTGCTCTACCAGCACCTGTTCTGGTTCTTCGGCCACCCTGAAGTCTACATCATGATCCTGCCGGCCTTCGG
CATCATCAGCCACATCATCGCCACCTTCTCCAAGAAGCCGGTATTCGGCTATCTCGGCATGGCCTATGCCATGGTGGCCA
TCGGCTTCGTCGGCTTCGTGGTCTGGGCGCACCATATGTTCACCACCGGCCTGGCGGTGGACACCCGCGCCTACTTCACC
GCCGCCACCCTGGTGATCGCCGTGCCCACCGGCATCAAGGTCTTCAGCTGGATCGCCACCATGTGGGGCGGATCCATCAC
CTTCCGGGTTCCCATGATGTGGGCGGTGGGTTTCGTCTTCCTGTTCACCATGGGCGGCGTCACCGGCGTGGTGCTGGCCA
ACAACCCCGTGGACGTGGCCCTGCACGACACCTATTACGTGGTCGCCCATTTCCACTACGTGCTGAGTCTGGGCGCGGTC
TTCGCCATCTTCGCCGGCTTCTACTACTGGATCGGCAAGATGAGCGGGCACCAGTATCCCGAGACCCTGGGCAAGATCCA
TTTCTGGCTGACCTTCGTGGGCGTCAATATCGCCTTCTTCCCGCAGCATTTCCTGGGCGCCCAGGGCATGCCGCGCCGCG
TGCCGGACTATCCCGACGCCTTCGCCGGGTGGAACATGGTGTCGTCCATCGGCGCCTATATCGCCTTTGCCGGCACGGCG
TTCTTCCTGGTGGTGGTGTGGCGTACCTTTACCGCCGGCAAGGCGGTGGAAGCCAATCCCTGGGGTTCGGGCGCCACCAC
GCTGGAATGGTCGGTCAGTTCGCCGCCGCCGCTGCACAGCTTCGACGGGCTGCCCCATATCGGCACTCCGGCGGAGTAA

Upstream 100 bases:

>100_bases
TCCTGGCCTGGGTCGCCCAGGCCAAGAAGACCTATGCCCACCTGGACGGCAGCCGTCCGGAAACTGCCGTCGCACTTGCC
GAAACCGGGGGGAAAAGTCC

Downstream 100 bases:

>100_bases
GGGGCATGAGCCCCCTGCGCCGGACCCAAGCGACCCTGGCGGGACTGGTAGTGATCATCGCCGCCATGGTCGGGCTGGTG
ATCGGCAGCGTGCCGCTCTA

Product: Heme/copper-type cytochrome/quinol oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSTAITHDHGHAQPHGWRRWLYSTNHKDIGTLYLIFSVIAGLLGGAMSIVIRMQLAHPGGTIFNGDWHMYNVFVTAHALT
MVFFTVMPALIGGFGNWFVPLMIGAPDMAFPRLNNISFWLLPPAFIMMLLSMVEGAGAGTGWTLYPPLSTAYHPDASVDF
AILGLHLAGISSVLGAINFVCTILNMRAPGMTMHRMPLFVWAMLVTAFLLLLSIPVLAGALTMLLTDRNFGTTFFAPAGG
GDPLLYQHLFWFFGHPEVYIMILPAFGIISHIIATFSKKPVFGYLGMAYAMVAIGFVGFVVWAHHMFTTGLAVDTRAYFT
AATLVIAVPTGIKVFSWIATMWGGSITFRVPMMWAVGFVFLFTMGGVTGVVLANNPVDVALHDTYYVVAHFHYVLSLGAV
FAIFAGFYYWIGKMSGHQYPETLGKIHFWLTFVGVNIAFFPQHFLGAQGMPRRVPDYPDAFAGWNMVSSIGAYIAFAGTA
FFLVVVWRTFTAGKAVEANPWGSGATTLEWSVSSPPPLHSFDGLPHIGTPAE

Sequences:

>Translated_532_residues
MSTAITHDHGHAQPHGWRRWLYSTNHKDIGTLYLIFSVIAGLLGGAMSIVIRMQLAHPGGTIFNGDWHMYNVFVTAHALT
MVFFTVMPALIGGFGNWFVPLMIGAPDMAFPRLNNISFWLLPPAFIMMLLSMVEGAGAGTGWTLYPPLSTAYHPDASVDF
AILGLHLAGISSVLGAINFVCTILNMRAPGMTMHRMPLFVWAMLVTAFLLLLSIPVLAGALTMLLTDRNFGTTFFAPAGG
GDPLLYQHLFWFFGHPEVYIMILPAFGIISHIIATFSKKPVFGYLGMAYAMVAIGFVGFVVWAHHMFTTGLAVDTRAYFT
AATLVIAVPTGIKVFSWIATMWGGSITFRVPMMWAVGFVFLFTMGGVTGVVLANNPVDVALHDTYYVVAHFHYVLSLGAV
FAIFAGFYYWIGKMSGHQYPETLGKIHFWLTFVGVNIAFFPQHFLGAQGMPRRVPDYPDAFAGWNMVSSIGAYIAFAGTA
FFLVVVWRTFTAGKAVEANPWGSGATTLEWSVSSPPPLHSFDGLPHIGTPAE
>Mature_531_residues
STAITHDHGHAQPHGWRRWLYSTNHKDIGTLYLIFSVIAGLLGGAMSIVIRMQLAHPGGTIFNGDWHMYNVFVTAHALTM
VFFTVMPALIGGFGNWFVPLMIGAPDMAFPRLNNISFWLLPPAFIMMLLSMVEGAGAGTGWTLYPPLSTAYHPDASVDFA
ILGLHLAGISSVLGAINFVCTILNMRAPGMTMHRMPLFVWAMLVTAFLLLLSIPVLAGALTMLLTDRNFGTTFFAPAGGG
DPLLYQHLFWFFGHPEVYIMILPAFGIISHIIATFSKKPVFGYLGMAYAMVAIGFVGFVVWAHHMFTTGLAVDTRAYFTA
ATLVIAVPTGIKVFSWIATMWGGSITFRVPMMWAVGFVFLFTMGGVTGVVLANNPVDVALHDTYYVVAHFHYVLSLGAVF
AIFAGFYYWIGKMSGHQYPETLGKIHFWLTFVGVNIAFFPQHFLGAQGMPRRVPDYPDAFAGWNMVSSIGAYIAFAGTAF
FLVVVWRTFTAGKAVEANPWGSGATTLEWSVSSPPPLHSFDGLPHIGTPAE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=61.3412228796844, Blast_Score=608, Evalue=1e-174,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=43.050193050193, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6226519, Length=526, Percent_Identity=57.4144486692015, Blast_Score=616, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=61.8012422360248, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=56.2753036437247, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6226522, Length=169, Percent_Identity=32.5443786982249, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6226521, Length=66, Percent_Identity=46.969696969697, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58166; Mature: 58035

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAITHDHGHAQPHGWRRWLYSTNHKDIGTLYLIFSVIAGLLGGAMSIVIRMQLAHPGG
CCCCEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
TIFNGDWHMYNVFVTAHALTMVFFTVMPALIGGFGNWFVPLMIGAPDMAFPRLNNISFWL
CEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEE
LPPAFIMMLLSMVEGAGAGTGWTLYPPLSTAYHPDASVDFAILGLHLAGISSVLGAINFV
CCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CTILNMRAPGMTMHRMPLFVWAMLVTAFLLLLSIPVLAGALTMLLTDRNFGTTFFAPAGG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GDPLLYQHLFWFFGHPEVYIMILPAFGIISHIIATFSKKPVFGYLGMAYAMVAIGFVGFV
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VWAHHMFTTGLAVDTRAYFTAATLVIAVPTGIKVFSWIATMWGGSITFRVPMMWAVGFVF
HHHHHHHHHCCEECHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHH
LFTMGGVTGVVLANNPVDVALHDTYYVVAHFHYVLSLGAVFAIFAGFYYWIGKMSGHQYP
HHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ETLGKIHFWLTFVGVNIAFFPQHFLGAQGMPRRVPDYPDAFAGWNMVSSIGAYIAFAGTA
HHHHHHHHHHHHHHHHHEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FFLVVVWRTFTAGKAVEANPWGSGATTLEWSVSSPPPLHSFDGLPHIGTPAE
HHHHHHHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STAITHDHGHAQPHGWRRWLYSTNHKDIGTLYLIFSVIAGLLGGAMSIVIRMQLAHPGG
CCCEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
TIFNGDWHMYNVFVTAHALTMVFFTVMPALIGGFGNWFVPLMIGAPDMAFPRLNNISFWL
CEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEE
LPPAFIMMLLSMVEGAGAGTGWTLYPPLSTAYHPDASVDFAILGLHLAGISSVLGAINFV
CCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CTILNMRAPGMTMHRMPLFVWAMLVTAFLLLLSIPVLAGALTMLLTDRNFGTTFFAPAGG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GDPLLYQHLFWFFGHPEVYIMILPAFGIISHIIATFSKKPVFGYLGMAYAMVAIGFVGFV
CCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VWAHHMFTTGLAVDTRAYFTAATLVIAVPTGIKVFSWIATMWGGSITFRVPMMWAVGFVF
HHHHHHHHHCCEECHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHH
LFTMGGVTGVVLANNPVDVALHDTYYVVAHFHYVLSLGAVFAIFAGFYYWIGKMSGHQYP
HHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ETLGKIHFWLTFVGVNIAFFPQHFLGAQGMPRRVPDYPDAFAGWNMVSSIGAYIAFAGTA
HHHHHHHHHHHHHHHHHEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FFLVVVWRTFTAGKAVEANPWGSGATTLEWSVSSPPPLHSFDGLPHIGTPAE
HHHHHHHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]