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The map label for this gene is tetA [H]

Identifier: 83311096

GI number: 83311096

Start: 2158631

End: 2158972

Strand: Reverse

Name: tetA [H]

Synonym: amb1997

Alternate gene names: 83311096

Gene position: 2158972-2158631 (Counterclockwise)

Preceding gene: 83311104

Following gene: 83311095

Centisome position: 43.47

GC content: 55.56

Gene sequence:

>342_bases
ATGAATACAAGGATTTTCATGGACTATTACCATGAGATTGATTTTCCATCTTTATTCGCGACGCGAGGCTGGATGGCCTT
CCCCATTATGATTCTTCTCGCTTCCGGCGGCATCGGGATGCCCGCGTTGCAGGCCATGCTGTCCAGGCAGGTAGATGACG
ACCATCAGGGACAGCTTCAAGGATCGCTCGCGGCTCTTACCAGCCTAACTTCGATCATTGGACCGCTGATCGTCACGGCG
ATTTATGCCCGCTCGGCGAGCACATGGAACGGGTTGGCATGGTTCGTAGGCGCCGCCCTATACCTTGTCTGGCTCCCCGC
GTTGCGTCCGCGTGCATTTTAG

Upstream 100 bases:

>100_bases
AGCGCATTGACCATCGGGATACTGAAGGGAGATTCCATCATCTCTTAGAAAGATCACCATCTCTTTTGTTTCAATTTGCA
TATAGCTACCTGGAGGATTT

Downstream 100 bases:

>100_bases
TTGGGAACAGTTCTCAACTCTGTCCCATAAAAATCAGCATATTCCCATCTATCCCATATCCAGCGCATTGACCATCGGGA
TACTGAAGGGAGATTCCATC

Product: hypothetical protein

Products: NA

Alternate protein names: TetA(C) [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MNTRIFMDYYHEIDFPSLFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQGSLAALTSLTSIIGPLIVTA
IYARSASTWNGLAWFVGAALYLVWLPALRPRAF

Sequences:

>Translated_113_residues
MNTRIFMDYYHEIDFPSLFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQGSLAALTSLTSIIGPLIVTA
IYARSASTWNGLAWFVGAALYLVWLPALRPRAF
>Mature_113_residues
MNTRIFMDYYHEIDFPSLFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQGSLAALTSLTSIIGPLIVTA
IYARSASTWNGLAWFVGAALYLVWLPALRPRAF

Specific function: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 12449; Mature: 12449

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRIFMDYYHEIDFPSLFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQ
CCCEEEEHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHH
GSLAALTSLTSIIGPLIVTAIYARSASTWNGLAWFVGAALYLVWLPALRPRAF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTRIFMDYYHEIDFPSLFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQ
CCCEEEEHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHH
GSLAALTSLTSIIGPLIVTAIYARSASTWNGLAWFVGAALYLVWLPALRPRAF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 383387; 6337373; 6307828; 1517220 [H]