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The map label for this gene is mcpA [H]

Identifier: 83310967

GI number: 83310967

Start: 2008004

End: 2010025

Strand: Reverse

Name: mcpA [H]

Synonym: amb1868

Alternate gene names: 83310967

Gene position: 2010025-2008004 (Counterclockwise)

Preceding gene: 83310968

Following gene: 83310966

Centisome position: 40.47

GC content: 70.92

Gene sequence:

>2022_bases
ATGACCGCCAAGTCCACCCTGCTCGACCGCTTCTCCATCCGGACCCGCATCTACGCTCTGGCCGGGGGACTGTGCGCCCT
GGCCGCCGGTCTGGCGGCTCTCGGCTATGTCTCCCTCAGCAATGTCATGGCCGACCTCGGCGAGGTCGGGCGCATCTCGG
CCAACGCCCAGCGGGTGGTGGAAATCGACCGGGACATCGCCGCCGCCCGCCGCAACGTCCTGGGCTTCGCCAATTCCGGC
GATGTCCGCATGCGTGATCGGGCCAATGAGCTGCTGACCACCCTGGCCAGCCAACTGGAAGAGTCGGTCGCCACCCATCG
CAACGCCGAGCGCCGGGCCATCCTGGTGGAGATGCGCGACCTGGTCGGCAGCTATCGCGCCTTGTTCGAGCAGGTGGTGG
CCAGCCGCCAGCGCCGCGACGAAAGCATCAAGCTGCAGCAGGGCGCGGCGGAAAAAGCCACCCAGACCATGAGCAGGCTG
CTGGCCGACGCCCTGGCCGCCGGCCGGGTCGATTTCGTCGCCCATGCGTCCCAGGCCCAGGAAAAGCTTTCCCTGGCGCG
GCTCAGCGTCGCCCGCTTCATCTCCATGGGAGATCCCGCCTTCATCGAGCGCGCCGAAGGCCATCTGAATGCTTTCGACG
GCATCGCCGCCACCCTGGACGCCCGCACCGGCAGCGCCGCCGACCGCGAGGGACTGGCCGAGGCGCGGAGCACCGTCGCC
GCCTTCCGCGACGCCATGCGCCAGACGGCCACCGCGATGATCTCGACCCGCCGGGTGGTGGAGGTGGACATGCCGGCCAC
CGGCGAGAAGTTCGCGGCCTTGGCGGCCGGCGTGCGCAACCTGCAAAAGGCCGCCGTCACCGAGGTCAGCCAGAGCAGCA
ACCGCCGCGCCGCCACCTTTACCATGGCCCTGGCCCTGGCCTCCCTGGCGGCGGTCGGCGGCGGCATGCTGTTCTCGGTG
ATCCTGGCCCGCGGCGTGGCGGTTCCCCTGACCGGCATGACCGACGCCATGTCCCACCTGGCCAAAGGCGACCACACCGT
CTCGATCCCCGGCGTCGGGCGCCAGGACGAGATCGGCGCCATGGCCAGCGCCGTCCAGGTGTTCCGCGACAGCATGGTCC
GGGCCGAAACCCTGGCCGCCGAGCAGGAGCAGGCCCGCCTCGCCCAGCTGGCCCGGGCCAGCCATATCGAGGCCTCGGCT
CGCCAGTTCGAAGCCAATGTCTTGAAGGTGGTCAGCGATCTGGGCCAGGCGGTGGGCCGGCTGGACAACACCTCCACCTC
CATGGCCGGCATCGCCACCAAGACCTCCGAGCGGGCCGCCGCCGTGGCCGCCGCCTCGACTCAAGCTACCTGCAACGTGC
AGACGGTGGCCGCCGCCGCCGAGGAGCTGTCCGCCTCGGTGACCGAAATCAGCCGGCGCGTCTCGGACTCCACCCGCATC
ACCGCCCAGGCGGTGGACATGGCCCGGCGGACCAATTCCCTGGTGGGCGGGCTGACTAGCAGCACCGACCGCATCGGCCA
GGTGGTCGGGCTGATCACCGACATCGCCGCCCAGACCAGCCTGCTGGCCATGAACGCCACCGTCGAGGCCGCCCGCGCCG
GGGAAAGCGGCAAGGGCTTCGCCGTGGTCGCGTCCGAGGTGAAGAAGCTGGCGCAGCAGACCGCCCGGGCCACCGGCGAG
ATCACCACCTATGTCGCCGAAGTCCAGGGCGCCGGCGCCCATACCGCCGGGGCGCTTCAGGACATCACCGGCATCATCGC
CCGCCTGGACGAGATCAGCAGCGCCATCGCCGCCGCGGTGGAGCAGCAAAGCGCCGCCACCTCGGAGATCGCCCGCAACG
CCAATCAGGCGGCCGGCGGCACCGAAGAGGTCAATCGCCACATCCACGGGGTGACCGAGGAGGCCAGCCAGACCGGCAGC
GCGTCGGGCCGGGTGCGCGGCGAGGCGGCCAGCCTGACCCGCCACGCCGCCGCCATTCACTCCGAGGTGGAGACCTTCCT
CTCCAACGTGCGCTGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCCCCGCGAAATACCTGTGCCGGAATGGCAAGCGCCGCTTTCTGCCCCATCCTGAACCTGTCTCGCCCTTCCACCCCG
ATCACCGGGAGATCCAAGAC

Downstream 100 bases:

>100_bases
CCCGCCCCTCCATTCGAAAGGACTTTCCCATGCACGTCAGCGAACGAATGGCCGCCATCCGGGCCAGAACGCAGGACACC
ATCGCCCGCCTGGACCGCGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MTAKSTLLDRFSIRTRIYALAGGLCALAAGLAALGYVSLSNVMADLGEVGRISANAQRVVEIDRDIAAARRNVLGFANSG
DVRMRDRANELLTTLASQLEESVATHRNAERRAILVEMRDLVGSYRALFEQVVASRQRRDESIKLQQGAAEKATQTMSRL
LADALAAGRVDFVAHASQAQEKLSLARLSVARFISMGDPAFIERAEGHLNAFDGIAATLDARTGSAADREGLAEARSTVA
AFRDAMRQTATAMISTRRVVEVDMPATGEKFAALAAGVRNLQKAAVTEVSQSSNRRAATFTMALALASLAAVGGGMLFSV
ILARGVAVPLTGMTDAMSHLAKGDHTVSIPGVGRQDEIGAMASAVQVFRDSMVRAETLAAEQEQARLAQLARASHIEASA
RQFEANVLKVVSDLGQAVGRLDNTSTSMAGIATKTSERAAAVAAASTQATCNVQTVAAAAEELSASVTEISRRVSDSTRI
TAQAVDMARRTNSLVGGLTSSTDRIGQVVGLITDIAAQTSLLAMNATVEAARAGESGKGFAVVASEVKKLAQQTARATGE
ITTYVAEVQGAGAHTAGALQDITGIIARLDEISSAIAAAVEQQSAATSEIARNANQAAGGTEEVNRHIHGVTEEASQTGS
ASGRVRGEAASLTRHAAAIHSEVETFLSNVRCA

Sequences:

>Translated_673_residues
MTAKSTLLDRFSIRTRIYALAGGLCALAAGLAALGYVSLSNVMADLGEVGRISANAQRVVEIDRDIAAARRNVLGFANSG
DVRMRDRANELLTTLASQLEESVATHRNAERRAILVEMRDLVGSYRALFEQVVASRQRRDESIKLQQGAAEKATQTMSRL
LADALAAGRVDFVAHASQAQEKLSLARLSVARFISMGDPAFIERAEGHLNAFDGIAATLDARTGSAADREGLAEARSTVA
AFRDAMRQTATAMISTRRVVEVDMPATGEKFAALAAGVRNLQKAAVTEVSQSSNRRAATFTMALALASLAAVGGGMLFSV
ILARGVAVPLTGMTDAMSHLAKGDHTVSIPGVGRQDEIGAMASAVQVFRDSMVRAETLAAEQEQARLAQLARASHIEASA
RQFEANVLKVVSDLGQAVGRLDNTSTSMAGIATKTSERAAAVAAASTQATCNVQTVAAAAEELSASVTEISRRVSDSTRI
TAQAVDMARRTNSLVGGLTSSTDRIGQVVGLITDIAAQTSLLAMNATVEAARAGESGKGFAVVASEVKKLAQQTARATGE
ITTYVAEVQGAGAHTAGALQDITGIIARLDEISSAIAAAVEQQSAATSEIARNANQAAGGTEEVNRHIHGVTEEASQTGS
ASGRVRGEAASLTRHAAAIHSEVETFLSNVRCA
>Mature_672_residues
TAKSTLLDRFSIRTRIYALAGGLCALAAGLAALGYVSLSNVMADLGEVGRISANAQRVVEIDRDIAAARRNVLGFANSGD
VRMRDRANELLTTLASQLEESVATHRNAERRAILVEMRDLVGSYRALFEQVVASRQRRDESIKLQQGAAEKATQTMSRLL
ADALAAGRVDFVAHASQAQEKLSLARLSVARFISMGDPAFIERAEGHLNAFDGIAATLDARTGSAADREGLAEARSTVAA
FRDAMRQTATAMISTRRVVEVDMPATGEKFAALAAGVRNLQKAAVTEVSQSSNRRAATFTMALALASLAAVGGGMLFSVI
LARGVAVPLTGMTDAMSHLAKGDHTVSIPGVGRQDEIGAMASAVQVFRDSMVRAETLAAEQEQARLAQLARASHIEASAR
QFEANVLKVVSDLGQAVGRLDNTSTSMAGIATKTSERAAAVAAASTQATCNVQTVAAAAEELSASVTEISRRVSDSTRIT
AQAVDMARRTNSLVGGLTSSTDRIGQVVGLITDIAAQTSLLAMNATVEAARAGESGKGFAVVASEVKKLAQQTARATGEI
TTYVAEVQGAGAHTAGALQDITGIIARLDEISSAIAAAVEQQSAATSEIARNANQAAGGTEEVNRHIHGVTEEASQTGSA
SGRVRGEAASLTRHAAAIHSEVETFLSNVRCA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=347, Percent_Identity=28.8184438040346, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=25.3869969040248, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788194, Length=257, Percent_Identity=32.6848249027237, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1789453, Length=217, Percent_Identity=33.1797235023041, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788195, Length=195, Percent_Identity=32.3076923076923, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70111; Mature: 69980

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKSTLLDRFSIRTRIYALAGGLCALAAGLAALGYVSLSNVMADLGEVGRISANAQRVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EIDRDIAAARRNVLGFANSGDVRMRDRANELLTTLASQLEESVATHRNAERRAILVEMRD
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LVGSYRALFEQVVASRQRRDESIKLQQGAAEKATQTMSRLLADALAAGRVDFVAHASQAQ
HHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EKLSLARLSVARFISMGDPAFIERAEGHLNAFDGIAATLDARTGSAADREGLAEARSTVA
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AFRDAMRQTATAMISTRRVVEVDMPATGEKFAALAAGVRNLQKAAVTEVSQSSNRRAATF
HHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TMALALASLAAVGGGMLFSVILARGVAVPLTGMTDAMSHLAKGDHTVSIPGVGRQDEIGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHH
MASAVQVFRDSMVRAETLAAEQEQARLAQLARASHIEASARQFEANVLKVVSDLGQAVGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDNTSTSMAGIATKTSERAAAVAAASTQATCNVQTVAAAAEELSASVTEISRRVSDSTRI
CCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TAQAVDMARRTNSLVGGLTSSTDRIGQVVGLITDIAAQTSLLAMNATVEAARAGESGKGF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVVASEVKKLAQQTARATGEITTYVAEVQGAGAHTAGALQDITGIIARLDEISSAIAAAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQSAATSEIARNANQAAGGTEEVNRHIHGVTEEASQTGSASGRVRGEAASLTRHAAAIH
HHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
SEVETFLSNVRCA
HHHHHHHHHCCCC
>Mature Secondary Structure 
TAKSTLLDRFSIRTRIYALAGGLCALAAGLAALGYVSLSNVMADLGEVGRISANAQRVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EIDRDIAAARRNVLGFANSGDVRMRDRANELLTTLASQLEESVATHRNAERRAILVEMRD
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LVGSYRALFEQVVASRQRRDESIKLQQGAAEKATQTMSRLLADALAAGRVDFVAHASQAQ
HHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EKLSLARLSVARFISMGDPAFIERAEGHLNAFDGIAATLDARTGSAADREGLAEARSTVA
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AFRDAMRQTATAMISTRRVVEVDMPATGEKFAALAAGVRNLQKAAVTEVSQSSNRRAATF
HHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TMALALASLAAVGGGMLFSVILARGVAVPLTGMTDAMSHLAKGDHTVSIPGVGRQDEIGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHH
MASAVQVFRDSMVRAETLAAEQEQARLAQLARASHIEASARQFEANVLKVVSDLGQAVGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDNTSTSMAGIATKTSERAAAVAAASTQATCNVQTVAAAAEELSASVTEISRRVSDSTRI
CCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TAQAVDMARRTNSLVGGLTSSTDRIGQVVGLITDIAAQTSLLAMNATVEAARAGESGKGF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVVASEVKKLAQQTARATGEITTYVAEVQGAGAHTAGALQDITGIIARLDEISSAIAAAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQSAATSEIARNANQAAGGTEEVNRHIHGVTEEASQTGSASGRVRGEAASLTRHAAAIH
HHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
SEVETFLSNVRCA
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]