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The map label for this gene is ubiG

Identifier: 83310710

GI number: 83310710

Start: 1736932

End: 1737681

Strand: Reverse

Name: ubiG

Synonym: amb1611

Alternate gene names: 83310710

Gene position: 1737681-1736932 (Counterclockwise)

Preceding gene: 83310719

Following gene: 83310707

Centisome position: 34.98

GC content: 67.87

Gene sequence:

>750_bases
GTGGAGTTGAAATTCATGGACCACGTGGGCACGGCATCGCCCGAGGAAATCGCCCGGTTCACCGCCATGGCCGAGGCCTG
GTGGGACCCGCAGGGCAAGTTCAAGCCGCTGCACCGCTTCAATCCCGTCCGCCTGGCCTTCATGCGCCGGCATTTCGCCG
CCCATTTCGGCCGTGACGAGAGCCTGATGCGCCCGTTCGAGGGCCTGACCCTGCTGGACGTGGGCAGCGGCGGCGGCCTG
CTGTCCGAGCCCCTGGCCCGCATGGGCTTTGCCGTCACCGGCATCGACGCGGGCGACAAGAACGTGGCCGTCGCCCGCCT
GCACGCCGAGCAGACCGGCGTGCCGGTGGACTACCGTGTATCAACGCCCGAGCAACTCGATCCCAACGAGGCCTTCGACG
TGGTGCTGTCCATGGAAGTGGTCGAGCACGTTCCCGACGTCTCGGCCTTCCTCGGCCACGCCACCGCCCGCCTGAAGCCC
GGCGGCGTGTTCATGGGCGCCACCCTGAACCGCACGGCCAAGGCCTGGGCCCTGGCGGTGGTCGGCGCCGAATACGTGCT
GGGCTGGCTGCCCAAGGGCACCCACGACTGGAACAAGTTCGTCCGCCCCTCGGAATTCGCCGCCATGCTGCGCGATCGCG
GCATCACCGTGCGCCAGATGGCCGGCATGGCCTTCAACCCGCTCAGCGACACCTGGCGCGAGACCGACAATCTCGACGTC
AATTACATGCTGTTCGGGGTCAAGGGCTAA

Upstream 100 bases:

>100_bases
GCGAAAAACTCTCGTTTGCGCGGTTGCCGCCGGAAGGGCGCGTATTCATACTCTGTCGCCCAGCGGGACGCAAGCACGGC
CCCCTTACGAAATGTTGCAG

Downstream 100 bases:

>100_bases
GCCCCGCCCGGCGGCGGAAACACCCCATTTCGGGGGCTTTTGCCCCCGATCCCCCAATCGGGAAGCACAGCTTCCCGAAC
CCTTCAGCTTATTAATCCAT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MELKFMDHVGTASPEEIARFTAMAEAWWDPQGKFKPLHRFNPVRLAFMRRHFAAHFGRDESLMRPFEGLTLLDVGSGGGL
LSEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVPVDYRVSTPEQLDPNEAFDVVLSMEVVEHVPDVSAFLGHATARLKP
GGVFMGATLNRTAKAWALAVVGAEYVLGWLPKGTHDWNKFVRPSEFAAMLRDRGITVRQMAGMAFNPLSDTWRETDNLDV
NYMLFGVKG

Sequences:

>Translated_249_residues
MELKFMDHVGTASPEEIARFTAMAEAWWDPQGKFKPLHRFNPVRLAFMRRHFAAHFGRDESLMRPFEGLTLLDVGSGGGL
LSEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVPVDYRVSTPEQLDPNEAFDVVLSMEVVEHVPDVSAFLGHATARLKP
GGVFMGATLNRTAKAWALAVVGAEYVLGWLPKGTHDWNKFVRPSEFAAMLRDRGITVRQMAGMAFNPLSDTWRETDNLDV
NYMLFGVKG
>Mature_249_residues
MELKFMDHVGTASPEEIARFTAMAEAWWDPQGKFKPLHRFNPVRLAFMRRHFAAHFGRDESLMRPFEGLTLLDVGSGGGL
LSEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVPVDYRVSTPEQLDPNEAFDVVLSMEVVEHVPDVSAFLGHATARLKP
GGVFMGATLNRTAKAWALAVVGAEYVLGWLPKGTHDWNKFVRPSEFAAMLRDRGITVRQMAGMAFNPLSDTWRETDNLDV
NYMLFGVKG

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=39.0946502057613, Blast_Score=192, Evalue=2e-49,
Organism=Escherichia coli, GI1788564, Length=232, Percent_Identity=43.5344827586207, Blast_Score=203, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI115533050, Length=251, Percent_Identity=34.2629482071713, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=274, Percent_Identity=30.2919708029197, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365311, Length=245, Percent_Identity=32.6530612244898, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24585589, Length=266, Percent_Identity=30.4511278195489, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_MAGSA (Q2W6W0)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_420974.1
- ProteinModelPortal:   Q2W6W0
- STRING:   Q2W6W0
- GeneID:   3804635
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb1611
- NMPDR:   fig|342108.5.peg.1439
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   KFITPDE
- PhylomeDB:   Q2W6W0
- ProtClustDB:   PRK05134
- BioCyc:   MMAG342108:AMB1611-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27531; Mature: 27531

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKFMDHVGTASPEEIARFTAMAEAWWDPQGKFKPLHRFNPVRLAFMRRHFAAHFGRDE
CCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
SLMRPFEGLTLLDVGSGGGLLSEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVPVDYRV
HHHCCCCCEEEEEECCCCCHHHHHHHHHCEEEEECCCCCCCEEEEEEEHHHCCCCEEEEE
STPEQLDPNEAFDVVLSMEVVEHVPDVSAFLGHATARLKPGGVFMGATLNRTAKAWALAV
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHH
VGAEYVLGWLPKGTHDWNKFVRPSEFAAMLRDRGITVRQMAGMAFNPLSDTWRETDNLDV
HHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHCCCCCCE
NYMLFGVKG
EEEEEEECC
>Mature Secondary Structure
MELKFMDHVGTASPEEIARFTAMAEAWWDPQGKFKPLHRFNPVRLAFMRRHFAAHFGRDE
CCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
SLMRPFEGLTLLDVGSGGGLLSEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVPVDYRV
HHHCCCCCEEEEEECCCCCHHHHHHHHHCEEEEECCCCCCCEEEEEEEHHHCCCCEEEEE
STPEQLDPNEAFDVVLSMEVVEHVPDVSAFLGHATARLKPGGVFMGATLNRTAKAWALAV
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHH
VGAEYVLGWLPKGTHDWNKFVRPSEFAAMLRDRGITVRQMAGMAFNPLSDTWRETDNLDV
HHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHCCCCCCE
NYMLFGVKG
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA