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The map label for this gene is bioC [C]

Identifier: 83310704

GI number: 83310704

Start: 1731608

End: 1732570

Strand: Reverse

Name: bioC [C]

Synonym: amb1605

Alternate gene names: 83310704

Gene position: 1732570-1731608 (Counterclockwise)

Preceding gene: 83310707

Following gene: 83310703

Centisome position: 34.88

GC content: 70.3

Gene sequence:

>963_bases
ATGACCAGACGTGCAACCCTGGCCGGCATGATCTTTCCTTCCCAGAAACGGCATGGACATGCCATACAGCCTGACATGAG
AATCTTCGACCGCCGCCTGGTGCGCAAGCACCGTGACCGCGCTGCCGGCAATTTCGTCGCCCACGACTTCCTGGTGCGCG
AAGTGGCCGAGCGCCTCGCCGACCGCCTGGACGACGTCAAGCGCCGCTTTCCCGTGGCCCTGGACCTGGGGTGCCATACC
GGCGAGATGGCCGACACCCTGAAGGGGCGCGGCGGCATCGAGACCCTGGTGCAATGCGACCTGTCGCCCGCCATGGCGGC
GAAGGCGGCGGCCAACGGCCACCCGACCCTGGCCGCCGACGAGGAATGGCTGCCCTTCGCGGCCCACAGCTTCGATCTAG
TGGTCTCGTGCCTGTCGCTGCACTGGGTCAACGACCTGCCGGGGACCTTGCTGCAGATCCGCCGGGTGCTCAAGCCCGAC
GGCCTGTTCATCGCCGCCCTGCTGGGAGCCGGCACCCTGGGCGAGTTGCGCCAGTCCCTGCAGGAGTCGGAACTGGCCGA
GGAAGGCGGGGTCAGCCCCCGCGTCGCCCCCTTCGCCGACGTCAAGGACCTGGGCGCATTGCTGCAGCGGGCCGGCTTCA
CCCTGCCGGTGGCCGATGCCGACACGGTGCCGGTCAGCTATGCCGATCCCATGCGGCTGATGGCCGATCTGCGCGGCATG
GGCGAGACCAATGCCGTGGCCGAGCAGCGCAAGGGCCTGACCCGGCGCGCCACCCTGCTGCGCGCCATCGCCCTTTACCA
GGAGCGCTTCGCCGGCCCCGACGGCCGCCTGCCCGCCACCTTCCAGGTGCTGACCATGACCGGCTGGGCGCCCCACCCCT
GCCAGCCCACCGCCGCGCCCCAGGGATGCGCCATTCCCGGCTTGCCCGACCTGATGGGCCGCATGAGCCCCGAGACCGAG
TGA

Upstream 100 bases:

>100_bases
GCCGAGAAAGACCATCCCCGACCAGCAGGTGGGGCACAGGCTGCCGGGCTCGGCCACTTCGGTCTGGCATGACAGGCAGA
GCGGCGGCAACAGCGCATCG

Downstream 100 bases:

>100_bases
TGCGCTTCGCCGCCCCCCTGGTCCGTGCCACCCTGATCAAGCGCTACAAGCGCTTCATGGCCGATGTGCGGTTCGACGAC
GGTACCGAGGTCACCGCCCA

Product: SAM-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTRRATLAGMIFPSQKRHGHAIQPDMRIFDRRLVRKHRDRAAGNFVAHDFLVREVAERLADRLDDVKRRFPVALDLGCHT
GEMADTLKGRGGIETLVQCDLSPAMAAKAAANGHPTLAADEEWLPFAAHSFDLVVSCLSLHWVNDLPGTLLQIRRVLKPD
GLFIAALLGAGTLGELRQSLQESELAEEGGVSPRVAPFADVKDLGALLQRAGFTLPVADADTVPVSYADPMRLMADLRGM
GETNAVAEQRKGLTRRATLLRAIALYQERFAGPDGRLPATFQVLTMTGWAPHPCQPTAAPQGCAIPGLPDLMGRMSPETE

Sequences:

>Translated_320_residues
MTRRATLAGMIFPSQKRHGHAIQPDMRIFDRRLVRKHRDRAAGNFVAHDFLVREVAERLADRLDDVKRRFPVALDLGCHT
GEMADTLKGRGGIETLVQCDLSPAMAAKAAANGHPTLAADEEWLPFAAHSFDLVVSCLSLHWVNDLPGTLLQIRRVLKPD
GLFIAALLGAGTLGELRQSLQESELAEEGGVSPRVAPFADVKDLGALLQRAGFTLPVADADTVPVSYADPMRLMADLRGM
GETNAVAEQRKGLTRRATLLRAIALYQERFAGPDGRLPATFQVLTMTGWAPHPCQPTAAPQGCAIPGLPDLMGRMSPETE
>Mature_319_residues
TRRATLAGMIFPSQKRHGHAIQPDMRIFDRRLVRKHRDRAAGNFVAHDFLVREVAERLADRLDDVKRRFPVALDLGCHTG
EMADTLKGRGGIETLVQCDLSPAMAAKAAANGHPTLAADEEWLPFAAHSFDLVVSCLSLHWVNDLPGTLLQIRRVLKPDG
LFIAALLGAGTLGELRQSLQESELAEEGGVSPRVAPFADVKDLGALLQRAGFTLPVADADTVPVSYADPMRLMADLRGMG
ETNAVAEQRKGLTRRATLLRAIALYQERFAGPDGRLPATFQVLTMTGWAPHPCQPTAAPQGCAIPGLPDLMGRMSPETE

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=290, Percent_Identity=46.551724137931, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI86792933, Length=288, Percent_Identity=41.3194444444444, Blast_Score=199, Evalue=4e-51,
Organism=Escherichia coli, GI1786994, Length=245, Percent_Identity=27.3469387755102, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535003, Length=292, Percent_Identity=36.986301369863, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19922210, Length=297, Percent_Identity=43.7710437710438, Blast_Score=238, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 34748; Mature: 34617

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRATLAGMIFPSQKRHGHAIQPDMRIFDRRLVRKHRDRAAGNFVAHDFLVREVAERLA
CCCCHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DRLDDVKRRFPVALDLGCHTGEMADTLKGRGGIETLVQCDLSPAMAAKAAANGHPTLAAD
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCC
EEWLPFAAHSFDLVVSCLSLHWVNDLPGTLLQIRRVLKPDGLFIAALLGAGTLGELRQSL
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
QESELAEEGGVSPRVAPFADVKDLGALLQRAGFTLPVADADTVPVSYADPMRLMADLRGM
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHCC
GETNAVAEQRKGLTRRATLLRAIALYQERFAGPDGRLPATFQVLTMTGWAPHPCQPTAAP
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
QGCAIPGLPDLMGRMSPETE
CCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TRRATLAGMIFPSQKRHGHAIQPDMRIFDRRLVRKHRDRAAGNFVAHDFLVREVAERLA
CCCHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DRLDDVKRRFPVALDLGCHTGEMADTLKGRGGIETLVQCDLSPAMAAKAAANGHPTLAAD
HHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCC
EEWLPFAAHSFDLVVSCLSLHWVNDLPGTLLQIRRVLKPDGLFIAALLGAGTLGELRQSL
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
QESELAEEGGVSPRVAPFADVKDLGALLQRAGFTLPVADADTVPVSYADPMRLMADLRGM
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHCC
GETNAVAEQRKGLTRRATLLRAIALYQERFAGPDGRLPATFQVLTMTGWAPHPCQPTAAP
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
QGCAIPGLPDLMGRMSPETE
CCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]