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The map label for this gene is corA [H]

Identifier: 83310193

GI number: 83310193

Start: 1162344

End: 1163648

Strand: Reverse

Name: corA [H]

Synonym: amb1094

Alternate gene names: 83310193

Gene position: 1163648-1162344 (Counterclockwise)

Preceding gene: 83310198

Following gene: 83310187

Centisome position: 23.43

GC content: 64.52

Gene sequence:

>1305_bases
ATGTCGCTGTTGGCCGTGACCGAATTGCTGAGCAAGCACAAGATCATCGAGGACATGCTGCGGGCCCAGGCCACGCGCCG
CCCGGAACTGGTCGAGACGGTGGTGCACAACCAGCACACCGCCGAGCTGCGGATGCTGCTGTCCCGGCTGTCGGCCGGCG
AGATCGGCCGGTCACTGGAAAGCGTTTCCCCCGACGACGCCAGGCTGCTGTGGCGCCATGTGGCGCAGGACCGCATGAAC
GATGTTCTGTGGGAGGTCTCCAGCGCGCTGGGCGAGCATCTGGCGGGCAATGTCGAGCCGCAATTCCTCAGCGGCGAGGT
CACGGCCTGTGAACTGGTGGACGGCCGCATGCGGATCATCCAGGTGGTGTCGCGCAGCGAGATGGAAGGGCTGCGGCCGA
TCTGGATCGATACCCTGGGCGCCTCCAAGTCGGAACGGGGCTGGCTCGGGCGGCATTTCGGCCTGGAACTGCCCGACCCC
GAGGATCTGACCGATCTGGAGGTCAGCGCCCGCTTCTATGTGGAGGAGAACGGCGAGCTTCACCTCCACTCCAATTTCCT
GCTGGACCGCGACGGCCAGTCCCGCAGCGTGCCGGTGGCCTTCATCGTCCATGCCGACACCCTGTTCACCGTGCGCAGCG
AGGAGCTGCCGGTGTTCCGCCTGCAGAGGCTGCGCATGCGCAGCCAGCCGGGCGAAGTGTCCGATTGCAAGGACCTGCTG
CTGGCCCTTTACGGCGCCGACATCGAATATTCCGCCGACGCCCTTGAAGACACCTACGAAACGCTGCGCCGGGTCGGCCG
CAAGGTGTTGAGCGAGAACATCAGCGATTCCGACGCCGCCCGCATCCTGGGCAACATCGCCGAGGAGGAGGACCTCAACG
GCCGGATTCGCGGCAACATGCTCGATACCCAGCGCGCCGTCTCATTCCTGCTGCGCGGCCGCCTGCTCAACACCATGCAG
ATGGAAGACGCCCGCGAGATCATCCGCGACATCGAATCGCTGAACACCCATACGGCGTTCCTGTTCGAAAAGATCAACTT
CCTGATGGATGCGACGGTGGGCTTCATCAACATCAACCAGAACCGCCGGGTCTCGCAGCTGACGGTGGCCGGCGTGGTGT
TCATGCCGCTCAACGTGCTGGCCGGCATCGGCGGAATGTCGGAATTCTCCATGATGACCCAGGGCGTTCCCTGGCCCCTG
TCCTATGGCGCCTTCACCGCCGGAATGATCCTGGTGGGATGGGGGACCTATACGGTCCTCAAGGTCTTCGAGGCCCGAAA
CGCCAAGAGACGGGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
TCCATGACAACTTTCAGACGGCTGAAGGCGCACCCTTGAATTCGCCGGGCCGCTTGCGCATGGTCTTTGGCTTTCCACCC
CATAATTCGGGCGAGAATTG

Downstream 100 bases:

>100_bases
CCCGGCGCCCTCAGCGCAGGGCCGGCAGCCCCCGCAGATAGCCCACCGCGCCGCGCTGGTCGACGCGCTTGCGCATCTCG
TCGCGGATCTCGGGGGGATA

Product: Mg2+ and Co2+ transporters; Mg/Co/Ni transporter MgtE

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSLLAVTELLSKHKIIEDMLRAQATRRPELVETVVHNQHTAELRMLLSRLSAGEIGRSLESVSPDDARLLWRHVAQDRMN
DVLWEVSSALGEHLAGNVEPQFLSGEVTACELVDGRMRIIQVVSRSEMEGLRPIWIDTLGASKSERGWLGRHFGLELPDP
EDLTDLEVSARFYVEENGELHLHSNFLLDRDGQSRSVPVAFIVHADTLFTVRSEELPVFRLQRLRMRSQPGEVSDCKDLL
LALYGADIEYSADALEDTYETLRRVGRKVLSENISDSDAARILGNIAEEEDLNGRIRGNMLDTQRAVSFLLRGRLLNTMQ
MEDAREIIRDIESLNTHTAFLFEKINFLMDATVGFININQNRRVSQLTVAGVVFMPLNVLAGIGGMSEFSMMTQGVPWPL
SYGAFTAGMILVGWGTYTVLKVFEARNAKRRAKA

Sequences:

>Translated_434_residues
MSLLAVTELLSKHKIIEDMLRAQATRRPELVETVVHNQHTAELRMLLSRLSAGEIGRSLESVSPDDARLLWRHVAQDRMN
DVLWEVSSALGEHLAGNVEPQFLSGEVTACELVDGRMRIIQVVSRSEMEGLRPIWIDTLGASKSERGWLGRHFGLELPDP
EDLTDLEVSARFYVEENGELHLHSNFLLDRDGQSRSVPVAFIVHADTLFTVRSEELPVFRLQRLRMRSQPGEVSDCKDLL
LALYGADIEYSADALEDTYETLRRVGRKVLSENISDSDAARILGNIAEEEDLNGRIRGNMLDTQRAVSFLLRGRLLNTMQ
MEDAREIIRDIESLNTHTAFLFEKINFLMDATVGFININQNRRVSQLTVAGVVFMPLNVLAGIGGMSEFSMMTQGVPWPL
SYGAFTAGMILVGWGTYTVLKVFEARNAKRRAKA
>Mature_433_residues
SLLAVTELLSKHKIIEDMLRAQATRRPELVETVVHNQHTAELRMLLSRLSAGEIGRSLESVSPDDARLLWRHVAQDRMND
VLWEVSSALGEHLAGNVEPQFLSGEVTACELVDGRMRIIQVVSRSEMEGLRPIWIDTLGASKSERGWLGRHFGLELPDPE
DLTDLEVSARFYVEENGELHLHSNFLLDRDGQSRSVPVAFIVHADTLFTVRSEELPVFRLQRLRMRSQPGEVSDCKDLLL
ALYGADIEYSADALEDTYETLRRVGRKVLSENISDSDAARILGNIAEEEDLNGRIRGNMLDTQRAVSFLLRGRLLNTMQM
EDAREIIRDIESLNTHTAFLFEKINFLMDATVGFININQNRRVSQLTVAGVVFMPLNVLAGIGGMSEFSMMTQGVPWPLS
YGAFTAGMILVGWGTYTVLKVFEARNAKRRAKA

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=304, Percent_Identity=38.8157894736842, Blast_Score=193, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 48781; Mature: 48649

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLAVTELLSKHKIIEDMLRAQATRRPELVETVVHNQHTAELRMLLSRLSAGEIGRSLE
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
SVSPDDARLLWRHVAQDRMNDVLWEVSSALGEHLAGNVEPQFLSGEVTACELVDGRMRII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHHH
QVVSRSEMEGLRPIWIDTLGASKSERGWLGRHFGLELPDPEDLTDLEVSARFYVEENGEL
HHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEEECCCCE
HLHSNFLLDRDGQSRSVPVAFIVHADTLFTVRSEELPVFRLQRLRMRSQPGEVSDCKDLL
EEECCEEEECCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
LALYGADIEYSADALEDTYETLRRVGRKVLSENISDSDAARILGNIAEEEDLNGRIRGNM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCC
LDTQRAVSFLLRGRLLNTMQMEDAREIIRDIESLNTHTAFLFEKINFLMDATVGFININQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCC
NRRVSQLTVAGVVFMPLNVLAGIGGMSEFSMMTQGVPWPLSYGAFTAGMILVGWGTYTVL
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCEEECHHHHHH
KVFEARNAKRRAKA
HHHHHHCCHHHCCC
>Mature Secondary Structure 
SLLAVTELLSKHKIIEDMLRAQATRRPELVETVVHNQHTAELRMLLSRLSAGEIGRSLE
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
SVSPDDARLLWRHVAQDRMNDVLWEVSSALGEHLAGNVEPQFLSGEVTACELVDGRMRII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHHH
QVVSRSEMEGLRPIWIDTLGASKSERGWLGRHFGLELPDPEDLTDLEVSARFYVEENGEL
HHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEEECCCCE
HLHSNFLLDRDGQSRSVPVAFIVHADTLFTVRSEELPVFRLQRLRMRSQPGEVSDCKDLL
EEECCEEEECCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
LALYGADIEYSADALEDTYETLRRVGRKVLSENISDSDAARILGNIAEEEDLNGRIRGNM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCC
LDTQRAVSFLLRGRLLNTMQMEDAREIIRDIESLNTHTAFLFEKINFLMDATVGFININQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCC
NRRVSQLTVAGVVFMPLNVLAGIGGMSEFSMMTQGVPWPLSYGAFTAGMILVGWGTYTVL
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCEEECHHHHHH
KVFEARNAKRRAKA
HHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]