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The map label for this gene is siaT [H]

Identifier: 83309992

GI number: 83309992

Start: 952704

End: 953987

Strand: Reverse

Name: siaT [H]

Synonym: amb0893

Alternate gene names: 83309992

Gene position: 953987-952704 (Counterclockwise)

Preceding gene: 83309993

Following gene: 83309988

Centisome position: 19.21

GC content: 63.94

Gene sequence:

>1284_bases
ATGAACTCCGCCGTCATCTTCGGGCTGCTGATCGTGCTGATGCTGACCGGCATGCCCATTTCCATCTCGCTGGGCCTCAC
CGTCCTGTCGTTTCTGTTCCTCTTCACCCAGGTTCCCATCGAATCCGTGGCGCTGAAGCTGTTCACCGGCATCGAGAAGT
TCGAGATCATGGCGATCCCGTTCTTCATCCTGGCCGGCAACTTCCTCACCCATGGCGGCGTGGCGCGGCGCATGATCAAC
TTCGCCACCGCCATGGTCGGCCACTGGTACGGCGGCCTGGGCCTGGCCGGCGTCATGGCCTGCGCCCTGTTCGCCGCCGT
GTCGGGATCGAGCCCGGCCACGGTGGTGGCCATCGGCTCCATCATCCTGCCCGCCATGGTCAAGCAGGGCTTCCCCAACA
AGTTCGGGGCGGGCGTCATCACCACCTCGGGCGCGCTGGGCATCCTGATCCCGCCCTCGCTGGTGATGGTCATGTACGCG
GTGGCCACCAACACCTCGGTGGGCGCCCTGTTCATGGCCGGCGTCATTCCCGGCCTGGTGCTGGCCACCGTGCTGGGCGC
GGTGACCTGGTACATCGCCTGGAAGAACGACTATCCTCGTCTGCCCCCCGCCACCTGGGCCCAGCGTTTCCGGGCGTTCC
GCGAGGCCATCTGGGGGTTGGCCCTGATCGTCATCGTCATCGGTGGCATCTATACCGGTGTCTTCACCCCCACCGAGGCG
GCGGCCATGAGCGCCGTCTACGCCTTCCTGATCGCCGTGTTCGTCTACAAGGATATGCCGCTGAAGGGCGTGGGCAAGAT
CCTGCTGTCCTCGGCCTCCATGTCGGCCATGCTGCTGTACATCATCACCAACGCGGTGCTGTTCAGCTTCGTCCTGGCCA
ACGAGAACATTCCCCACGCCATCGCCGACTGGATCGTCGGCAAGGAGTTGGGAGTGATCGCCTTCCTGCTGGTGGTCAAC
GTGCTGCTGCTGGTGGCGGGCAATTTCATGGAGCCCAGCTCCATCGTGCTGATCATGGCTCCCATCCTGTTCCCGGTGGC
CATGAAGCTGGGCATCGACCCGATTCACTTCGGCATCCTGATCGTGGTCAACATGGAGGTGGGCATGTGCCACCCCCCGG
TGGGCCTCAATCTCTATGTGGCATCGGGAATCACCAAGATGGGCATCACCGAGCTGACCGTGGCGGTGTGGCCCTGGCTG
CTGGCCATGCTGGGCTTTTTGATGGTGGTGACCTACTGGCCGCCGCTGTCCATCTGGCTGCCCCGGGCGTTGGGGGTGAT
GTAA

Upstream 100 bases:

>100_bases
AGCGCGCCGCCCAGGACATCAACTGGTTCGAGATGTCGGACAATCTTCACCCCAAGGACGCCAAAGACGACAAGGGTGAT
CACCAGGGGGAGAAGCGGCC

Downstream 100 bases:

>100_bases
AGCCTCAGGGGCAGGCCCGCAGCCGGGTCTGCCCCTCTTCTTTTTTCAGATCACCACAGACGCCGTTCACGCACAGGCGC
CAGTCGGCGGTGAAATCCGA

Product: TRAP-type C4-dicarboxylate transport system

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNSAVIFGLLIVLMLTGMPISISLGLTVLSFLFLFTQVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVARRMIN
FATAMVGHWYGGLGLAGVMACALFAAVSGSSPATVVAIGSIILPAMVKQGFPNKFGAGVITTSGALGILIPPSLVMVMYA
VATNTSVGALFMAGVIPGLVLATVLGAVTWYIAWKNDYPRLPPATWAQRFRAFREAIWGLALIVIVIGGIYTGVFTPTEA
AAMSAVYAFLIAVFVYKDMPLKGVGKILLSSASMSAMLLYIITNAVLFSFVLANENIPHAIADWIVGKELGVIAFLLVVN
VLLLVAGNFMEPSSIVLIMAPILFPVAMKLGIDPIHFGILIVVNMEVGMCHPPVGLNLYVASGITKMGITELTVAVWPWL
LAMLGFLMVVTYWPPLSIWLPRALGVM

Sequences:

>Translated_427_residues
MNSAVIFGLLIVLMLTGMPISISLGLTVLSFLFLFTQVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVARRMIN
FATAMVGHWYGGLGLAGVMACALFAAVSGSSPATVVAIGSIILPAMVKQGFPNKFGAGVITTSGALGILIPPSLVMVMYA
VATNTSVGALFMAGVIPGLVLATVLGAVTWYIAWKNDYPRLPPATWAQRFRAFREAIWGLALIVIVIGGIYTGVFTPTEA
AAMSAVYAFLIAVFVYKDMPLKGVGKILLSSASMSAMLLYIITNAVLFSFVLANENIPHAIADWIVGKELGVIAFLLVVN
VLLLVAGNFMEPSSIVLIMAPILFPVAMKLGIDPIHFGILIVVNMEVGMCHPPVGLNLYVASGITKMGITELTVAVWPWL
LAMLGFLMVVTYWPPLSIWLPRALGVM
>Mature_427_residues
MNSAVIFGLLIVLMLTGMPISISLGLTVLSFLFLFTQVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVARRMIN
FATAMVGHWYGGLGLAGVMACALFAAVSGSSPATVVAIGSIILPAMVKQGFPNKFGAGVITTSGALGILIPPSLVMVMYA
VATNTSVGALFMAGVIPGLVLATVLGAVTWYIAWKNDYPRLPPATWAQRFRAFREAIWGLALIVIVIGGIYTGVFTPTEA
AAMSAVYAFLIAVFVYKDMPLKGVGKILLSSASMSAMLLYIITNAVLFSFVLANENIPHAIADWIVGKELGVIAFLLVVN
VLLLVAGNFMEPSSIVLIMAPILFPVAMKLGIDPIHFGILIVVNMEVGMCHPPVGLNLYVASGITKMGITELTVAVWPWL
LAMLGFLMVVTYWPPLSIWLPRALGVM

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=382, Percent_Identity=32.1989528795811, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45457; Mature: 45457

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSAVIFGLLIVLMLTGMPISISLGLTVLSFLFLFTQVPIESVALKLFTGIEKFEIMAIP
CCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHH
FFILAGNFLTHGGVARRMINFATAMVGHWYGGLGLAGVMACALFAAVSGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IILPAMVKQGFPNKFGAGVITTSGALGILIPPSLVMVMYAVATNTSVGALFMAGVIPGLV
HHHHHHHHCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LATVLGAVTWYIAWKNDYPRLPPATWAQRFRAFREAIWGLALIVIVIGGIYTGVFTPTEA
HHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AAMSAVYAFLIAVFVYKDMPLKGVGKILLSSASMSAMLLYIITNAVLFSFVLANENIPHA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IADWIVGKELGVIAFLLVVNVLLLVAGNFMEPSSIVLIMAPILFPVAMKLGIDPIHFGIL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEE
IVVNMEVGMCHPPVGLNLYVASGITKMGITELTVAVWPWLLAMLGFLMVVTYWPPLSIWL
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PRALGVM
HHHHCCC
>Mature Secondary Structure
MNSAVIFGLLIVLMLTGMPISISLGLTVLSFLFLFTQVPIESVALKLFTGIEKFEIMAIP
CCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHH
FFILAGNFLTHGGVARRMINFATAMVGHWYGGLGLAGVMACALFAAVSGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IILPAMVKQGFPNKFGAGVITTSGALGILIPPSLVMVMYAVATNTSVGALFMAGVIPGLV
HHHHHHHHCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LATVLGAVTWYIAWKNDYPRLPPATWAQRFRAFREAIWGLALIVIVIGGIYTGVFTPTEA
HHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AAMSAVYAFLIAVFVYKDMPLKGVGKILLSSASMSAMLLYIITNAVLFSFVLANENIPHA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IADWIVGKELGVIAFLLVVNVLLLVAGNFMEPSSIVLIMAPILFPVAMKLGIDPIHFGIL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEE
IVVNMEVGMCHPPVGLNLYVASGITKMGITELTVAVWPWLLAMLGFLMVVTYWPPLSIWL
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PRALGVM
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]