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The map label for this gene is qor [H]

Identifier: 83309851

GI number: 83309851

Start: 812049

End: 813020

Strand: Reverse

Name: qor [H]

Synonym: amb0752

Alternate gene names: 83309851

Gene position: 813020-812049 (Counterclockwise)

Preceding gene: 83309852

Following gene: 83309850

Centisome position: 16.37

GC content: 68.11

Gene sequence:

>972_bases
ATGAAAGCCGTCGTCTGCCCCGCTTTCGGCCAGGATCTGGTCGTCACCGACTTTCCCGCCCCCGCCATGATCCCGGGCGG
CGTGCGCATCGCCGTGCATGCGGCCGGCGTCAACTTCGCCGACTCGCTGATCACCGGCGGCAAGTACCAGGAAAAGATGG
AGCCGCCCTTCGTGCCGGGCATGGAACTGGCCGGCGTGGTCACCGAGGTGGCCGACGGCGTCACCACGGCCAAGCCCGGC
GACCGGGTGATGGCCACAGTGACCGGCGGCGCCTTCGCCGAGGAAGCGGTGTGCGATCAGACCGACGTCTATGTGCTGCC
CGACGGCCTCGATTTCGTCACCGCCGCCGGTTTTCCCGTGGCCTACGGCACCTCGCATCTGGGCCTCAAGGGCAAGGCGG
GGCTTAAATCCGGCGAGACCCTGGTGGTGCACGGCGCGGCCGGGGGCGTCGGCCTGACCGCCGTCGAGGTGGGCCGGGCG
CTGGGCGCCACCGTCATCGGCACCGCCGGTGGGCCGGACAAGGTCAAGGTGGCGCTGGAGCACGGCGCCCATTTCGGCAT
CGACTACAAGGCCGAGGATATCCGCGAGCGGGTCAAGGCCCTGACCGACGGCCGGGGCGCCGACGTGGTCTACGATCCGG
TGGGCGGACAGGTGTTCGACGCGTCCTTGCGCTCCATCGCCGCCGACGGCCGCATTCTGATCATCGGCTTTGCCGGCGGC
ACGGTGCAGCAGATCCCCGCCAACATCCTGCTGGTCAAGAACGTCACGGTGATCGGCTATTACTGGGGCGCCTACCGCAA
GATTGCGCCGCAAATGGTCCGCGATTCCCTGGGCGAATGCCTGGACTGGTGGGCGGCGGGCAAGCTGTCGCCCCATGTCT
CCAAGGTCATGGACCTGTCCCAGGCGGTAGAGGCCATCGGATTGCTGAAGGGCCGCGCCGCCACGGGGAAAATCGTCCTC
ATTTGTCGATGA

Upstream 100 bases:

>100_bases
CGGTGCCGGTTGGGACACGCCGTTCCAGACGGAGATCCCTCCTCCCGTTGGTCGTCGGGATGACAGACACTTCTGCAACC
CGCCATTCCGGGAAAATCTC

Downstream 100 bases:

>100_bases
GGACGAAACAATCTGTTACCCGATGCGTAATTTACGCGAGGGGGTATATTAGATAGCCTGACTGCAAGTTCTCTTTCCCC
AAAGCCCTTCGGAGACCTCG

Product: NADPH:quinone reductase and related Zn-dependent oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKAVVCPAFGQDLVVTDFPAPAMIPGGVRIAVHAAGVNFADSLITGGKYQEKMEPPFVPGMELAGVVTEVADGVTTAKPG
DRVMATVTGGAFAEEAVCDQTDVYVLPDGLDFVTAAGFPVAYGTSHLGLKGKAGLKSGETLVVHGAAGGVGLTAVEVGRA
LGATVIGTAGGPDKVKVALEHGAHFGIDYKAEDIRERVKALTDGRGADVVYDPVGGQVFDASLRSIAADGRILIIGFAGG
TVQQIPANILLVKNVTVIGYYWGAYRKIAPQMVRDSLGECLDWWAAGKLSPHVSKVMDLSQAVEAIGLLKGRAATGKIVL
ICR

Sequences:

>Translated_323_residues
MKAVVCPAFGQDLVVTDFPAPAMIPGGVRIAVHAAGVNFADSLITGGKYQEKMEPPFVPGMELAGVVTEVADGVTTAKPG
DRVMATVTGGAFAEEAVCDQTDVYVLPDGLDFVTAAGFPVAYGTSHLGLKGKAGLKSGETLVVHGAAGGVGLTAVEVGRA
LGATVIGTAGGPDKVKVALEHGAHFGIDYKAEDIRERVKALTDGRGADVVYDPVGGQVFDASLRSIAADGRILIIGFAGG
TVQQIPANILLVKNVTVIGYYWGAYRKIAPQMVRDSLGECLDWWAAGKLSPHVSKVMDLSQAVEAIGLLKGRAATGKIVL
ICR
>Mature_323_residues
MKAVVCPAFGQDLVVTDFPAPAMIPGGVRIAVHAAGVNFADSLITGGKYQEKMEPPFVPGMELAGVVTEVADGVTTAKPG
DRVMATVTGGAFAEEAVCDQTDVYVLPDGLDFVTAAGFPVAYGTSHLGLKGKAGLKSGETLVVHGAAGGVGLTAVEVGRA
LGATVIGTAGGPDKVKVALEHGAHFGIDYKAEDIRERVKALTDGRGADVVYDPVGGQVFDASLRSIAADGRILIIGFAGG
TVQQIPANILLVKNVTVIGYYWGAYRKIAPQMVRDSLGECLDWWAAGKLSPHVSKVMDLSQAVEAIGLLKGRAATGKIVL
ICR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=31.5950920245399, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=31.5950920245399, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=29.4498381877023, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=37.4384236453202, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI22538446, Length=320, Percent_Identity=27.5, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI22538444, Length=320, Percent_Identity=27.5, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI24308257, Length=345, Percent_Identity=27.536231884058, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI28557745, Length=334, Percent_Identity=26.9461077844311, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI41872631, Length=256, Percent_Identity=26.171875, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=28.0612244897959, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI47519420, Length=369, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI67078404, Length=289, Percent_Identity=24.9134948096886, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=301, Percent_Identity=32.5581395348837, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI226510941, Length=115, Percent_Identity=39.1304347826087, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=332, Percent_Identity=27.710843373494, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI133901712, Length=190, Percent_Identity=33.6842105263158, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133901710, Length=190, Percent_Identity=33.6842105263158, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=266, Percent_Identity=25.9398496240602, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=321, Percent_Identity=24.9221183800623, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=320, Percent_Identity=29.6875, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323961, Length=349, Percent_Identity=26.9340974212034, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=27.0029673590504, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=337, Percent_Identity=24.6290801186944, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=332, Percent_Identity=24.3975903614458, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221330659, Length=307, Percent_Identity=25.0814332247557, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920632, Length=307, Percent_Identity=25.0814332247557, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581345, Length=219, Percent_Identity=27.8538812785388, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33297; Mature: 33297

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVCPAFGQDLVVTDFPAPAMIPGGVRIAVHAAGVNFADSLITGGKYQEKMEPPFVPG
CCEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHCCCCCHHHCCCCCCCC
MELAGVVTEVADGVTTAKPGDRVMATVTGGAFAEEAVCDQTDVYVLPDGLDFVTAAGFPV
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEECCCCCCHHCCCCCE
AYGTSHLGLKGKAGLKSGETLVVHGAAGGVGLTAVEVGRALGATVIGTAGGPDKVKVALE
EECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCEEEEEE
HGAHFGIDYKAEDIRERVKALTDGRGADVVYDPVGGQVFDASLRSIAADGRILIIGFAGG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHHHHHHCCCCEEEEEEECCC
TVQQIPANILLVKNVTVIGYYWGAYRKIAPQMVRDSLGECLDWWAAGKLSPHVSKVMDLS
CHHHCCCCEEEEECEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QAVEAIGLLKGRAATGKIVLICR
HHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MKAVVCPAFGQDLVVTDFPAPAMIPGGVRIAVHAAGVNFADSLITGGKYQEKMEPPFVPG
CCEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHCCCCCHHHCCCCCCCC
MELAGVVTEVADGVTTAKPGDRVMATVTGGAFAEEAVCDQTDVYVLPDGLDFVTAAGFPV
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEECCCCCCHHCCCCCE
AYGTSHLGLKGKAGLKSGETLVVHGAAGGVGLTAVEVGRALGATVIGTAGGPDKVKVALE
EECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCEEEEEE
HGAHFGIDYKAEDIRERVKALTDGRGADVVYDPVGGQVFDASLRSIAADGRILIIGFAGG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHHHHHHCCCCEEEEEEECCC
TVQQIPANILLVKNVTVIGYYWGAYRKIAPQMVRDSLGECLDWWAAGKLSPHVSKVMDLS
CHHHCCCCEEEEECEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QAVEAIGLLKGRAATGKIVLICR
HHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]