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The map label for this gene is tsaA [H]

Identifier: 83309763

GI number: 83309763

Start: 715512

End: 716135

Strand: Reverse

Name: tsaA [H]

Synonym: amb0664

Alternate gene names: 83309763

Gene position: 716135-715512 (Counterclockwise)

Preceding gene: 83309768

Following gene: 83309762

Centisome position: 14.42

GC content: 63.94

Gene sequence:

>624_bases
ATGTCCGACACGATTCAGAGCCCGACCTCCCTGGTCACCAAAGCCGCCCCTGACTTCACCGCCCCGGCGGTGATGCCGGA
CAACGAGATCAATCCGGCGTTCAACCTGAAGTCGTACCTGGCTGGCTCCTACGGCATCGTGTTCTTCTATCCGCTGGACT
TCACCTTCGTGTGTCCGTCGGAGATCCTGGCCCACGATCACCGCGTCAAGGCCTTCGCCGAGCGCAACACCAAGGTCATC
GCCGTCAGCGTCGATTCCCACTTCACCCACCTGGCCTGGAAGAACACCCCCGTCGACAAGGGCGGCCTGGGCAACGTCCA
GTTCCCCATGGTGGCCGACCTGACCAAGGACATCGCCAAGTCCTATGGCGTCCTGCTGCCGGGTGGCGTGGCGCTGCGCG
GCACCTTCGTGATCGACAAGAACGGCGTGGTCCAGTCGGCCCATGTGAACAACCTGCCGCTGGGCCGCAACGTGGACGAG
GCGCTGCGCCTGATCGACGCGCTGCAGTTCTCGGAAGAGCATGGCGAGGTCTGCCCCGCCGGCTGGAACAAGGGCAAGGC
CGGCATGAAGCCCAATCCCAACGGCGTTGCCGAATACCTGGCCAAGCACGCTTCCGAGCTGTAA

Upstream 100 bases:

>100_bases
TGGCAGCTGTTTTGTAATCATTCCATCTTGCGCGACACGGCAATCCAGACTAGATTTGTCGGCATCATTTTTGTCCAAGC
CCTATGAGGGAGCCTTTCTA

Downstream 100 bases:

>100_bases
GGCTTTTGTAAGATAGGGAGGGCGCGCCGCTTGCCAGCGGCGCGCCCTCTCCTTATGCTGTGACGCAATAATTTCGAAAA
GTCCGGGAAGCATCGCGATG

Product: peroxiredoxin

Products: NA

Alternate protein names: 26 kDa antigen; Thioredoxin reductase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDTIQSPTSLVTKAAPDFTAPAVMPDNEINPAFNLKSYLAGSYGIVFFYPLDFTFVCPSEILAHDHRVKAFAERNTKVI
AVSVDSHFTHLAWKNTPVDKGGLGNVQFPMVADLTKDIAKSYGVLLPGGVALRGTFVIDKNGVVQSAHVNNLPLGRNVDE
ALRLIDALQFSEEHGEVCPAGWNKGKAGMKPNPNGVAEYLAKHASEL

Sequences:

>Translated_207_residues
MSDTIQSPTSLVTKAAPDFTAPAVMPDNEINPAFNLKSYLAGSYGIVFFYPLDFTFVCPSEILAHDHRVKAFAERNTKVI
AVSVDSHFTHLAWKNTPVDKGGLGNVQFPMVADLTKDIAKSYGVLLPGGVALRGTFVIDKNGVVQSAHVNNLPLGRNVDE
ALRLIDALQFSEEHGEVCPAGWNKGKAGMKPNPNGVAEYLAKHASEL
>Mature_206_residues
SDTIQSPTSLVTKAAPDFTAPAVMPDNEINPAFNLKSYLAGSYGIVFFYPLDFTFVCPSEILAHDHRVKAFAERNTKVIA
VSVDSHFTHLAWKNTPVDKGGLGNVQFPMVADLTKDIAKSYGVLLPGGVALRGTFVIDKNGVVQSAHVNNLPLGRNVDEA
LRLIDALQFSEEHGEVCPAGWNKGKAGMKPNPNGVAEYLAKHASEL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=203, Percent_Identity=49.7536945812808, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=50.7936507936508, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=50.7936507936508, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=50.7936507936508, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI5802974, Length=194, Percent_Identity=51.0309278350515, Blast_Score=198, Evalue=2e-51,
Organism=Homo sapiens, GI32483377, Length=162, Percent_Identity=54.9382716049383, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=49.4791666666667, Blast_Score=195, Evalue=3e-50,
Organism=Homo sapiens, GI4758638, Length=194, Percent_Identity=30.4123711340206, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI33188454, Length=85, Percent_Identity=50.5882352941176, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1786822, Length=153, Percent_Identity=35.9477124183007, Blast_Score=110, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193204376, Length=199, Percent_Identity=46.2311557788945, Blast_Score=184, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI32565831, Length=195, Percent_Identity=46.6666666666667, Blast_Score=183, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17554494, Length=162, Percent_Identity=50, Blast_Score=177, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI25153706, Length=180, Percent_Identity=26.1111111111111, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=43.1578947368421, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320661, Length=190, Percent_Identity=40.5263157894737, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319407, Length=186, Percent_Identity=30.1075268817204, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656348, Length=200, Percent_Identity=50, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17864676, Length=200, Percent_Identity=50, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17738015, Length=195, Percent_Identity=50.7692307692308, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17157991, Length=190, Percent_Identity=44.7368421052632, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24641739, Length=190, Percent_Identity=44.7368421052632, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=45.360824742268, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI17975518, Length=181, Percent_Identity=33.1491712707182, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24652436, Length=181, Percent_Identity=32.5966850828729, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24652434, Length=181, Percent_Identity=32.5966850828729, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22320; Mature: 22188

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTIQSPTSLVTKAAPDFTAPAVMPDNEINPAFNLKSYLAGSYGIVFFYPLDFTFVCPS
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCEEEECCH
EILAHDHRVKAFAERNTKVIAVSVDSHFTHLAWKNTPVDKGGLGNVQFPMVADLTKDIAK
HHHHCHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
SYGVLLPGGVALRGTFVIDKNGVVQSAHVNNLPLGRNVDEALRLIDALQFSEEHGEVCPA
HCCEECCCCEEEEEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GWNKGKAGMKPNPNGVAEYLAKHASEL
CCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SDTIQSPTSLVTKAAPDFTAPAVMPDNEINPAFNLKSYLAGSYGIVFFYPLDFTFVCPS
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCEEEECCH
EILAHDHRVKAFAERNTKVIAVSVDSHFTHLAWKNTPVDKGGLGNVQFPMVADLTKDIAK
HHHHCHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
SYGVLLPGGVALRGTFVIDKNGVVQSAHVNNLPLGRNVDEALRLIDALQFSEEHGEVCPA
HCCEECCCCEEEEEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GWNKGKAGMKPNPNGVAEYLAKHASEL
CCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 1987145 [H]