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The map label for this gene is arcB

Identifier: 82752215

GI number: 82752215

Start: 2652847

End: 2653857

Strand: Reverse

Name: arcB

Synonym: SAB2509c

Alternate gene names: 82752215

Gene position: 2653857-2652847 (Counterclockwise)

Preceding gene: 82752216

Following gene: 82752214

Centisome position: 96.77

GC content: 33.04

Gene sequence:

>1011_bases
ATGACAGAAATTCAAAAACCGTATGATTTAAAAGGCAGATCATTATTAAAAGAAAGTGATTTTACCAAAGTAGAATTCGA
AGGACTTATTGATTTTGCAATTACATTAAAAGAGTATAAGAAAAACGGTATTAAGCATCACTACTTATCTGGAAAAAATA
TTGCACTACTATTCGAAAAGAATTCGACGAGAACGCGTGCAGCGTTTACAGTTGCGTCTATTGATTTAGGTGCACATCCA
GAATTTTTAGGGAAAAATGATATTCAATTAGGCAAAAAAGAATCTGTAGAGGATACTGCGAAAGTATTAGGTAGAATGTT
CGATGGTATTGAATTCCGTGGTTTTTCACAACAAGCTGTTGAAGATTTAGCGAAGTTCTCTGGTGTACCGGTGTGGAATG
GATTAACAGACGATTGGCATCCTACACAAATGTTAGCTGATTTTATGACAATAAAAGAGAATTTTGGATATCTAGAAGGA
ATAAACTTAACTTACGTTGGAGATGGACGTAATAATATTGCGCATTCATTAATGGTAGCAGGTGCTATGTTAGGTGTTAA
TGTAAGAATTTGTACACCTAAATCATTAAATCCAAAAGAGGCATATGTTGATATTGCAAAAGAAAAAGCGAGTCAATATG
GTGGTTCAGTCATGATTACGGATAATATTGCAGAAGCAGTTGAAAATACAGATGCTATATATACAGATGTTTGGGTATCG
ATGGGTGAAGAAAGTGAATTTGAACAACGTATTAATTTATTAAAAGACTATCAAGTGAATCAACAGATGTTTGATTTAAC
AGGTAAAGATTCAACGATATTCTTACATTGTTTACCAGCATTCCATGATACAAATACACTTTATGGACAAGAAATTTATG
AAAAATATGGATTAGCTGAAATGGAAGTTACAGACCAAATCTTTAGAAGTGAACATTCAAAAGTGTTTGATCAAGCTGAA
AATAGAATGCATACAATTAAGGCAGTAATGGCAGCAACATTGGGGAGTTAA

Upstream 100 bases:

>100_bases
GCGAGTTGGTACGTGGACGTGGGGGTCCTAGATGTATGAGTCAACCACTATTCAGAGAAGACATTTAACGTAATAAATTA
TAGAAACGAGGGTGAAAATA

Downstream 100 bases:

>100_bases
TCACTAAATGGAACGATATGAATATGATGTGTCTGATGATATAAGTGTCATATACAGACACCTCATATTGGTATTAAAGG
AGAAATGAATATGAACGAAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTEIQKPYDLKGRSLLKESDFTKVEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHP
EFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEG
INLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAE
NRMHTIKAVMAATLGS

Sequences:

>Translated_336_residues
MTEIQKPYDLKGRSLLKESDFTKVEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHP
EFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEG
INLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAE
NRMHTIKAVMAATLGS
>Mature_335_residues
TEIQKPYDLKGRSLLKESDFTKVEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHPE
FLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGI
NLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVSM
GEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAEN
RMHTIKAVMAATLGS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=37.3493975903614, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI18105007, Length=340, Percent_Identity=26.7647058823529, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=51.3595166163142, Blast_Score=344, Evalue=4e-96,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=51.2269938650307, Blast_Score=343, Evalue=9e-96,
Organism=Escherichia coli, GI48994908, Length=346, Percent_Identity=26.3005780346821, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI2367364, Length=335, Percent_Identity=27.7611940298507, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=179, Percent_Identity=30.7262569832402, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=34.3283582089552, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322331, Length=279, Percent_Identity=25.8064516129032, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24642586, Length=338, Percent_Identity=27.2189349112426, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37791; Mature: 37660

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIQKPYDLKGRSLLKESDFTKVEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
CCCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
HHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCEEECCEEEEEECCCHHHHHHHHHH
GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHH
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
CCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCH
MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEIQKPYDLKGRSLLKESDFTKVEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
CCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
HHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCEEECCEEEEEECCCHHHHHHHHHH
GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHH
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
CCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCH
MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA